CN206434300U - A kind of spy is multispectral to excite imaging system - Google Patents
A kind of spy is multispectral to excite imaging system Download PDFInfo
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- CN206434300U CN206434300U CN201621028445.1U CN201621028445U CN206434300U CN 206434300 U CN206434300 U CN 206434300U CN 201621028445 U CN201621028445 U CN 201621028445U CN 206434300 U CN206434300 U CN 206434300U
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- light source
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- laser light
- imaging
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Abstract
The utility model provides that a kind of spy is multispectral to excite imaging system, including:Laser light source unit, white light source portion, optical coupling portion and based endoscopic imaging portion, laser light source unit and white light source portion connect optical coupling portion respectively, and optical coupling portion connection based endoscopic imaging portion, laser light source unit includes at least one LASER Light Source;One of LASER Light Source at least one LASER Light Source sends laser, and white light source portion sends white light, and laser and white light enter based endoscopic imaging portion after being merged through optical coupling portion, realizes and multispectral is excited into picture.The multispectral laser spectrum for exciting imaging system to select laser light source unit according to imaging demand of spy of the present utility model, and adjust the light source power in laser light source unit and white light source portion, excitation source power is big, spectral band is narrow, image contrast is high, the selection of spectral band is flexible, meets the imaging demand of multi-spectrum endoscopic.
Description
Technical field
The utility model is related to endoscope illuminator and technical field of imaging, more particularly to a kind of spy is multispectral is excited into
As system.
Background technology
White light endoscopic is a kind of common checking tool, with the advantage such as invasive low, wound is small.White light endoscopic leads to
Clear high-quality coloured image can be often provided, it is convenient to check diseased region and abdomen be opened, but due to some lesions
Position or important structure and normal portions have similar shape, color etc., and lesion is distinguished only by coloured image
There is certain difficulty in position and normal portions.
In recent years, optical molecular image technology is increasingly becoming study hotspot, and it can observe cell knot on a molecular scale
Structure make a variation, wherein fluorescent molecules imaging technology as optical molecular iconography an important branch, by high specific, height
The advantage such as spatial resolution, high time resolution, fast and convenient, achieves good development, in recent years fluorescent molecules imaging skill
Art is applied to also achieve preferable progress in pathological tissues identification.
Fluorescent molecules imaging technology is applied in endoscopic imaging, can improve image contrast, fluorescent specific mark
Position can help to recognize specific position.And in order to not lose color image information, white light and fluorescence binary channels simultaneously into
Picture, can demarcating privileged site in real time in coloured image, there is provided more imaging region information.
For the imaging of existing white fluorescence binary channels, multispectral excitation source is typically using the illumination of full spectral coverage plus optical filter
The mode of switching produces multiple excitation spectrum light sources, and this mode has that excitation source power is small, spectral band is wide, imaging pair
The problem of not higher than degree.
Utility model content
(1) technical problem to be solved
In order to solve the problem of prior art is present, the utility model provides a kind of multispectral picture that is excited into of spy and is
System.
(2) technical scheme
The utility model provides that a kind of spy is multispectral to excite imaging system, including:Laser light source unit 200, white light
Light source portion 100, optical coupling portion 400 and based endoscopic imaging portion 500;Wherein, 100 points of the laser light source unit 200 and white light source portion
The optical coupling portion 400 is not connected, and the optical coupling portion 400 connects the based endoscopic imaging portion 500, the laser light source unit 200
Including at least one LASER Light Source;One of LASER Light Source at least one described LASER Light Source sends laser, described white
Radiant portion 100 sends white light, and the laser and white light enter the based endoscopic imaging portion after being merged through the optical coupling portion 400
500, realize and multispectral be excited into picture.
Preferably, in addition to:Control unit 300;The control unit 300 connects the white light source portion 100 and LASER Light Source
One of LASER Light Source in portion 200, its at least one LASER Light Source according to being selected imaging demand sends laser, and adjusts
Save the light source power in the LASER Light Source and white light source portion 100.
Preferably, the optical coupling portion 400 includes:White light source interface 401, LASER Light Source interface 402, white light optical fiber
403rd, laser fiber 404, fiber coupler 405, multimode fibre 406, optical tunnel 407 and endoscope illuminator interface 408;Wherein,
The white light source interface 401 is connected with white light source portion 100, and the white light source interface 401 connects light through white light optical fiber 403
Fine coupler 405, the LASER Light Source interface 402 is connected with laser light source unit 200, and the LASER Light Source interface 402 is through laser
Optical fiber 404 connects fiber coupler 405, and the fiber coupler 405 connects optical tunnel 407, the even light through multimode fibre 406
Rod 407 connects endoscopic imaging portion 500 through endoscope illuminator interface 408.
Preferably, the white light enters optical coupling portion 400 by white light source interface 401, and through the white light optical fiber 403
Into fiber coupler 405;The laser enters optical coupling portion 400 by LASER Light Source interface 402, and through laser fiber 404
Into fiber coupler 405;The fiber coupler 405 by white light together with laser fusion, and through the multimode fibre 406
Send into optical tunnel 407, after the optical tunnel 407 uniformly collimation, interior peep into is sent into by the endoscope illuminator interface 408
Picture portion 500.
Preferably, the based endoscopic imaging portion 500 includes endoscopic portion 502;The endoscopic portion 502 includes:Endoscope light
Source introducing port, the endoscope illuminator introducing port is matched with the endoscope illuminator interface 408 of optical coupling portion, the endoscope illuminator
Interface 408 threads directly into endoscope illuminator introducing port by screw socket.
Preferably, the optical tunnel 407 is polygon glass column, or the ducted body that inwall is reflecting surface.
Preferably, in addition to:Image processing part 600;The based endoscopic imaging portion 500 also includes:Imaging section 501, and with institute
Image processing part 600 is stated to connect;The endoscopic portion 502 also includes:It is imaged light guide bundles and excites illumination light guide bundles;By optical coupling
Laser and white light after the fusion of portion 400 excite illumination light guide bundles irradiation search coverage 503 described in, from the search coverage 503
The light for reflecting or sending enters imaging section 501 through the imaging light guide bundles, and image is sent into image processing part by the imaging section 501
600 are handled, and obtain colour-fluorescent fusion image.
Preferably, at least one described LASER Light Source includes:LASER Light Source 1, LASER Light Source 2 202 and LASER Light Source
3 203;Wherein, the LASER Light Source 1 be 785 ± 10nm wave bands laser, for excite indocyanine green and
IRDye800CW fluorescence imaging reagents;The LASER Light Source 2 202 is the laser of 685 ± 10nm wave bands, for exciting
IRDye680CW fluorescence imaging reagents;The LASER Light Source 3 203 is the laser of 390-440nm wave bands, for autofluorescence
Imaging;The white light source portion 100 is the white light source of 400-650nm wave bands, for providing illumination to search coverage 503, is gone forward side by side
Row visual light imaging.
Preferably, the imaging section 501 includes:White light camera and fluorescence camera.
Preferably, the control unit 300 is computer or single-chip microcomputer.
(3) beneficial effect
Excite imaging system to have following to have it can be seen from the above technical proposal that spy of the present utility model is multispectral
Beneficial effect:
Control unit can select the laser spectrum of laser light source unit according to imaging demand, and adjust laser light source unit and white
The light source power in radiant portion, excitation source power is big, spectral band is narrow, and image contrast is high, and the selection of spectral band is flexible
It is convenient, meet the imaging demand of multi-spectrum endoscopic.
Brief description of the drawings
Fig. 1 for the utility model embodiment the multispectral overall schematic for exciting imaging system of spy;
Fig. 2 is the structure chart of the optical coupling portion of the utility model embodiment;
Fig. 3 for the utility model embodiment the multispectral structure chart for exciting imaging system of spy.
【Symbol description】
100- white light sources portion;200- laser light source units;300- control units;400- optical coupling portions;500 based endoscopic imaging portions;
600- image processing parts;
201- LASER Light Sources one;202- LASER Light Sources two;203- LASER Light Sources three;401- white light source interfaces;402- swashs
Radiant interface;403- white light optical fiber;404- laser fibers;405- fiber couplers;406- multimode fibres;407- optical tunnels;
408- endoscope illuminator interfaces;501- imaging sections;502- endoscopic portions;503- search coverages.
Embodiment
The utility model, which is that a kind of spy is multispectral, excites imaging system, and the system includes:White light source portion, can be provided
The excitation source portion of three spectral coverage laser, optical coupling portion, its by white light and laser fusion to together, while send into endoscopic portion,
Control unit, it controls output and the regulation light source power of white light source and excitation source;Endoscopic imaging portion, carry out it is multispectral into
Picture.The utility model is merged multiple spectral coverage light by light path fusion method, and the exciting light of multiple single spectral coverages can be produced simultaneously,
Meet the imaging demand of multi-spectrum endoscopic.
For the purpose of this utility model, technical scheme and advantage is more clearly understood, below in conjunction with specific embodiment, and
Referring to the drawings, the utility model is further described.
In the utility model embodiment, imaging system is excited there is provided a kind of spy is multispectral as shown in Figure 1, bag
Include:Laser light source unit 200, white light source portion 100, optical coupling portion 400, control unit 300, based endoscopic imaging portion 500 and image procossing
Portion 600.Wherein,
Please referring also to Fig. 3, laser light source unit 200 includes LASER Light Source 1, LASER Light Source 2 202 and LASER Light Source
3 203, LASER Light Source 1 sends the first laser that wave band is 785 ± 10nm, for exciting indocyanine green and IRDye800CW
Deng fluorescence imaging reagent, LASER Light Source 2 202 sends the second laser that wave band is 685 ± 10nm, for exciting IRDye680CW
Deng fluorescence imaging reagent;LASER Light Source 3 203 sends the 3rd laser that wave band is 390-440nm, for auto-fluorescence imaging;In vain
Radiant portion 100 sends the white light of 400-650nm wave bands, for search coverage 503 provide illumination, and carry out visible ray into
Picture.
Fig. 2 is referred to, what optical coupling portion 400 sent for merging the white light and laser light source unit 200 in white light source portion 100
Laser.Wherein, optical coupling portion 400 includes:White light optical fiber 403, laser fiber 404, fiber coupler 405, the and of multimode fibre 406
Optical tunnel 407, optical coupling portion 400 is connected by white light source interface 401 with white light source portion 100, white light source interface 401
Fiber coupler 405 is connected through white light optical fiber 403, optical coupling portion 400 passes through LASER Light Source interface 402 and laser light source unit 200
It is connected, LASER Light Source interface 402 connects fiber coupler 405 through laser fiber 404, and fiber coupler 405 is through multimode fibre
406 connection optical tunnels 407, optical tunnel 407 connects endoscopic imaging portion 500 through endoscope illuminator interface 408.
Wherein, white light optical fiber 403 and laser fiber 404 are coupled as multimode fibre 406 by fiber coupler 405, and it passes through
By white light optical fiber 403 and laser fiber 404 and together with burn and melt stretching, optical fiber core condenses together to form multimode fibre 406.
The ducted body that optical tunnel 407 can be polygon glass column or inwall is reflecting surface, incides even light
The light of rod inwall reaches the purpose of uniform light after multiple reflections.
The connection white light source of control unit 300 portion 100 and laser light source unit 200, it selects LASER Light Source according to imaging demand
The laser spectrum in portion 200, and adjust the light source power in laser light source unit 200 and white light source portion 100.
Control unit 300 can be using controllers such as computer, single-chip microcomputers.
Based endoscopic imaging portion 500 includes imaging section 501 and endoscopic portion 502, and is connected with image processing part 600, wherein, into
Picture portion 501 includes white light camera and fluorescence camera, and endoscopic portion 502 includes endoscope illuminator introducing port, imaging light guide bundles and swashed
Issue permit bright light guide bundles.Endoscope illuminator introducing port is matched with the endoscope illuminator interface 408 of optical coupling portion 400, endoscope illuminator
Interface 408 can thread directly into endoscope illuminator introducing port, convenient operation, it is easy to dismantle by screw socket.Fluorescence camera can include
Near-infrared fluorescent camera and Cerenkov fluorescence camera.
The spy of the utility model embodiment is multispectral to excite imaging system, laser light source unit 200 and white light source portion
100 send laser and white light, and white light enters optical coupling portion 400 by white light source interface 401, and enters through white light optical fiber 403
Fiber coupler 405;Laser enters optical coupling portion 400 by LASER Light Source interface 402, and enters optical fiber through laser fiber 404
Coupler 405;
Fiber coupler 405 sends into white light in optical tunnel 407 together with laser fusion, and through multimode fibre 406, warp
After the uniform collimation of optical tunnel 407, based endoscopic imaging portion is sent into by endoscope illuminator interface 408 and endoscope illuminator introducing port
500, and through exciting illumination light guide bundles irradiation search coverage 503, the imaged light guide bundles of light for reflecting or sending from search coverage 503
Into imaging section 501, it is imaged by white light camera and fluorescence camera, and image feeding image processing part 600 is handled, so that
Obtain colour-fluorescent fusion image.Wherein, control unit 300 can select the laser light of laser light source unit 200 according to imaging demand
Spectrum, specifically, the control of control unit 300 LASER Light Source 1, LASER Light Source 2 202 and LASER Light Source 3 203, selection wherein it
One sends laser, for example, it is desired to when exciting the fluorescence imaging reagent such as indocyanine green and IRDye800CW, select LASER Light Source one
201 send first laser laser, it is necessary to which when exciting the fluorescence imaging reagent such as IRDye680CW, selection LASER Light Source 2 202 is sent
Second laser is, it is necessary to which during auto-fluorescence imaging, selection LASER Light Source 3 203 sends the 3rd laser;And laser light can be adjusted
Source 1, LASER Light Source 2 202, the light source power in LASER Light Source 3 203 and white light source portion 100, to realize multispectral excite
Imaging.
As can be seen here, spy of the present utility model is multispectral excites imaging system, and control unit can be according to imaging demand
The laser spectrum of laser light source unit is selected, and adjusts the light source power in laser light source unit and white light source portion, relative to existing
The multispectral excitation source of technology produces multiple excitation spectrum light sources by the way of the illumination of full spectral coverage plus optical filter switching, excites
Light source power is big, and spectral band is narrow, and the selection of spectral band is flexible, meets the imaging demand of multi-spectrum endoscopic.
So far, the present embodiment is described in detail combined accompanying drawing.According to above description, those skilled in the art
Multispectral to spy of the present utility model imaging system should be excited to have clear understanding.
It should be noted that in accompanying drawing or specification text, the implementation for not illustrating or describing is affiliated technology
Form known to a person of ordinary skill in the art, is not described in detail in field.In addition, above-mentioned definition to each element and not only limiting
Various concrete structures, shape or the mode mentioned in embodiment, those of ordinary skill in the art can be carried out simply more to it
Change or replace, for example:
(1) direction term mentioned in embodiment, is only ginseng such as " on ", " under ", "front", "rear", "left", "right"
The direction of accompanying drawing is examined, not for limiting protection domain of the present utility model;
(2) consideration that above-described embodiment can be based on design and reliability, the collocation that is mixed with each other is used or and other embodiment
Mix and match is used, i.e., technical characteristic not in be the same as Example can freely form more embodiments.
In summary, spy of the present utility model is multispectral excites imaging system, and control unit can be according to imaging demand
The laser spectrum of laser light source unit is selected, and adjusts the light source power in laser light source unit and white light source portion, relative to existing
The multispectral excitation source of technology produces multiple excitation spectrum light sources by the way of the illumination of full spectral coverage plus optical filter switching, excites
Light source power is big, and spectral band is narrow, and the selection of spectral band is flexible, meets the imaging demand of multi-spectrum endoscopic.
Particular embodiments described above, has carried out entering one to the purpose of this utility model, technical scheme and beneficial effect
Step is described in detail, be should be understood that and be the foregoing is only specific embodiment of the utility model, is not limited to this
Utility model, all within spirit of the present utility model and principle, any modification, equivalent substitution and improvements done etc. all should be wrapped
It is contained within protection domain of the present utility model.
Claims (10)
1. a kind of spy is multispectral to excite imaging system, it is characterised in that including:Laser light source unit (200), white light source portion
(100), optical coupling portion (400) and based endoscopic imaging portion (500);Wherein,
The laser light source unit (200) and white light source portion (100) connect the optical coupling portion (400), the optical coupling respectively
Portion (400) connects the based endoscopic imaging portion (500), and the laser light source unit (200) includes at least one LASER Light Source;
One of LASER Light Source at least one described LASER Light Source sends laser, and the white light source portion (100) sends
White light, the laser and white light enter the based endoscopic imaging portion (500) after being merged through the optical coupling portion (400), realize light more
Spectrum is excited into picture.
2. spy as claimed in claim 1 is multispectral to excite imaging system, it is characterised in that also include:Control unit
(300);
The control unit (300) connects the white light source portion (100) and laser light source unit (200), and it is selected according to imaging demand
The one of LASER Light Source selected at least one described LASER Light Source sends laser, and adjusts the LASER Light Source and white light light
The light source power in source portion (100).
3. spy as claimed in claim 1 is multispectral to excite imaging system, it is characterised in that
The optical coupling portion (400) includes:White light source interface (401), LASER Light Source interface (402), white light optical fiber (403),
Laser fiber (404), fiber coupler (405), multimode fibre (406), optical tunnel (407) and endoscope illuminator interface (408);
Wherein,
The white light source interface (401) is connected with white light source portion (100), and the white light source interface (401) is through white light light
Fine (403) connection fiber coupler (405), the LASER Light Source interface (402) is connected with laser light source unit (200), described to swash
Radiant interface (402) connects fiber coupler (405) through laser fiber (404), and the fiber coupler (405) is through multimode light
Fine (406) connection optical tunnel (407), the optical tunnel (407) connects endoscopic imaging portion through endoscope illuminator interface (408)
(500)。
4. spy as claimed in claim 3 is multispectral to excite imaging system, it is characterised in that
The white light enters optical coupling portion (400) by white light source interface (401), and enters through the white light optical fiber (403)
Fiber coupler (405);The laser enters optical coupling portion (400) by LASER Light Source interface (402), and through laser fiber
(404) fiber coupler (405) is entered;
White light is sent into optical tunnel by the fiber coupler (405) together with laser fusion, and through the multimode fibre (406)
(407) in, after the optical tunnel (407) uniformly collimation, based endoscopic imaging portion is sent into by the endoscope illuminator interface (408)
(500)。
5. spy as claimed in claim 3 is multispectral to excite imaging system, it is characterised in that the based endoscopic imaging portion
(500) endoscopic portion (502) is included;
The endoscopic portion (502) includes:Endoscope illuminator introducing port, the endoscope illuminator introducing port and optical coupling portion it is interior
Endoscope light source interface (408) is matched, and the endoscope illuminator interface (408) threads directly into endoscope illuminator by screw socket and imported
Mouthful.
6. spy as claimed in claim 3 is multispectral to excite imaging system, it is characterised in that the optical tunnel (407) is
Polygon glass column, or the ducted body that inwall is reflecting surface.
7. spy as claimed in claim 5 is multispectral to excite imaging system, it is characterised in that also include:Image processing part
(600);The based endoscopic imaging portion (500) also includes:Imaging section (501), and be connected with described image processing unit (600);It is described
Endoscopic portion (502) also includes:It is imaged light guide bundles and excites illumination light guide bundles;
Illumination light guide bundles irradiation search coverage (503) is excited described in by the laser and white light after optical coupling portion (400) fusion, from
Search coverage (503) reflection or the light sent enter imaging section (501), the imaging section through the imaging light guide bundles
(501) image is sent into image processing part (600) to be handled, obtains colour-fluorescent fusion image.
8. spy as claimed in claim 1 is multispectral to excite imaging system, it is characterised in that at least one described laser light
Source includes:LASER Light Source one (201), LASER Light Source two (202) and LASER Light Source three (203);Wherein,
The LASER Light Source one (201) is the laser of 785 ± 10nm wave bands, for exciting indocyanine green and IRDye800CW glimmering
Photoimaging reagent;
The LASER Light Source two (202) is the laser of 685 ± 10nm wave bands, for exciting IRDye680CW fluorescence imagings to try
Agent;
The LASER Light Source three (203) is the laser of 390-440nm wave bands, for auto-fluorescence imaging;
The white light source portion (100) is the white light source of 400-650nm wave bands, for providing illumination to search coverage (503), and
Carry out visual light imaging.
9. spy as claimed in claim 7 is multispectral to excite imaging system, it is characterised in that imaging section (501) bag
Include:White light camera and fluorescence camera.
10. spy as claimed in claim 2 is multispectral to excite imaging system, it is characterised in that the control unit (300) is
Computer or single-chip microcomputer.
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CN201621028445.1U CN206434300U (en) | 2016-08-31 | 2016-08-31 | A kind of spy is multispectral to excite imaging system |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109945971A (en) * | 2019-04-11 | 2019-06-28 | 福州大学 | Visualization fluorescent optical sensor and preparation method thereof for UV detection |
CN111974753A (en) * | 2020-08-05 | 2020-11-24 | 中国人民解放军陆军装甲兵学院 | Laser cleaning cleanliness online monitoring device, system and method |
-
2016
- 2016-08-31 CN CN201621028445.1U patent/CN206434300U/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109945971A (en) * | 2019-04-11 | 2019-06-28 | 福州大学 | Visualization fluorescent optical sensor and preparation method thereof for UV detection |
CN111974753A (en) * | 2020-08-05 | 2020-11-24 | 中国人民解放军陆军装甲兵学院 | Laser cleaning cleanliness online monitoring device, system and method |
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