CN206355178U - A kind of experimental rig that animal model is depressurized for brain trauma controlling - Google Patents
A kind of experimental rig that animal model is depressurized for brain trauma controlling Download PDFInfo
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- CN206355178U CN206355178U CN201621041652.0U CN201621041652U CN206355178U CN 206355178 U CN206355178 U CN 206355178U CN 201621041652 U CN201621041652 U CN 201621041652U CN 206355178 U CN206355178 U CN 206355178U
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- Prior art keywords
- pressure
- hydraulic shock
- pipe
- experimental rig
- housing
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Abstract
The utility model discloses a kind of experimental rig that animal model is depressurized for brain trauma controlling, including housing, the pressure sensor of pressure in housing can be monitored by being provided with described housing；One end of hydraulic shock pipe is communicated with the top of described housing, the other end of hydraulic shock pipe is connected with one end of check valve, the other end of check valve is connected with one end of hydraulic shock room, the end face of the other end of hydraulic shock room is elastic membrane, pressure regulation liquid is filled with hydraulic shock room, the liquid supplementation pipe that liquid is adjusted for supplementing pressure, jump bit impact elasticity film are also communicated with hydraulic shock room so that the pressure regulation liquid in hydraulic shock room is unidirectionally entered in hydraulic shock pipe by check valve.The animal model of a set of controlling decompression can be set up for brain trauma, by changing the conditions such as hydraulic shock intensity and decompression rate, controlling that can be systematically to brain trauma depressurizes the experiment of carry out system.
Description
Technical field
The utility model belongs to brain damage testing field, is related to controlling decompression, and in particular to one kind is used for brain trauma control
Property processed depressurizes the experimental rig of animal model.
Background technology
The levels of thyroid hormone in craniocerebral trauma patients death rate is up to 30%~60%, and how to reduce the prognosis of the death rate and improvement patient is
The important topic that neurosurgical doctor pays special attention to.Standard large trauma craniotomy has obtained extensively should in such patient
With.
Decompressive craniectomy (decompressive craniectomuy, DC) is the treatment intractable cranium of severe traumatic head injury
The effective ways of high pressure patient.Controlling decompression is effectively reduced the correlation such as acute encephalocele in art, postoperative cerebral infarction simultaneously in art
Send out the incidence of disease.
Complicated by postoperative cerebral infarction is one of severe complication after craniotomy on patients with severe craniocerebral injury, is seen children are quite a few,
The death rate and disability rate of patient can substantially be increased, how discussion reduces severe cranial brain injury cerebral infarction incidence and improvement
The prognosis of patient has important research meaning.The heavy cranium of retrospective comparative study operative treatment children is depressurized using controlling in art
Brain injury patient, works well.
Based on above-mentioned clinical experience, controlling decompression method has clinically had more application, but in clinical practice
The experience of more dependence medical personnel is operated in journey, and still nobody depressurizes carry out science to the controlling of encephalic operation
System experimentation, provides certain law for clinic and guides, also no in the prior art to be tested for controlling decompression
Special purpose device so that researcher is difficult to the controlling decompression test of system.
The content of the invention
In view of the deficienciess of the prior art, the purpose of this utility model is to be used for brain trauma controlling there is provided one kind
The experimental rig of animal model is depressurized, solves to be difficult in the prior art systematically for brain trauma being controlled property decompression test
Technical problem.
In order to solve the above-mentioned technical problem, the utility model, which is adopted the following technical scheme that, is achieved：
A kind of experimental rig that animal model is depressurized for brain trauma controlling, including it is placed on experimental animal for sealing
The pressure sensor of pressure in housing can be monitored by being provided with the housing that the bottom on head is opened, described housing；
One end of hydraulic shock pipe, the other end of hydraulic shock pipe and the one of check valve are communicated with the top of described housing
End is connected, and the other end of check valve is connected with one end of hydraulic shock room, and the end face of the other end of hydraulic shock room is elastic membrane,
It is filled with hydraulic shock room on pressure regulation liquid, hydraulic shock room and is also communicated with the liquid supplementation pipe that liquid is adjusted for supplementing pressure,
Jump bit impact elasticity film so that the pressure regulation liquid in hydraulic shock room is unidirectionally entered in hydraulic shock pipe by check valve；
Pressure is also communicated with described housing and maintains pipe, pressure maintains to be provided with pressure-regulating valve, housing and pressure on pipe
When power maintains to adjust liquid full of pressure in pipe, pressure maintains the pressure that pipe is used in adjustment housings.
The utility model also has following distinguishing feature：
Described housing is transparent shell.
Described housing is made of glass or transparent plastic.
Described transparent plastic is lucite.
Described elastic membrane is made of elastomeric material.
Described pressure regulation liquid is synthetic cerebrospinal fluid or physiological saline.
Described hydraulic shock room is arranged in fixed seat.
The utility model compared with prior art, has the following technical effect that：
Experimental rig of the present utility model, the animal model of a set of controlling decompression can be set up for brain trauma, is passed through
The condition such as hydraulic shock intensity and decompression rate of change, controlling that can be systematically to brain trauma depressurizes the examination of carry out system
Test, be easy to experimenter to find optimal controlling reduced pressure, provide beneficial guidance for clinical practice operation, it is to avoid directly
Depressurize the secondary damage brought.
Brief description of the drawings
Fig. 1 is overall structure diagram of the present utility model.
Fig. 2 is use state schematic diagram of the present utility model.
The implication of the label of each in figure is：1- housings, 2- pressure sensors, 3- hydraulic shock pipes, 4- check valves, 5- hydraulic pressure
Impulse chamber, 6- elastic membranes, 7- liquid supplementation pipes, 8- jump bits, 9- pressure maintains pipe, 10- pressure-regulating valves, 11- experimental animals, 12-
Fixed seat.
Explanation is further explained in detail to particular content of the present utility model with reference to embodiments.
Embodiment
Specific embodiment of the utility model given below is, it is necessary to which explanation is that the utility model is not limited to following tool
Body embodiment, all equivalents done on the basis of technical scheme each fall within protection domain of the present utility model.
Embodiment：
Above-mentioned technical proposal is deferred to, as depicted in figs. 1 and 2, the present embodiment provides a kind of brain trauma controlling that is used for and depressurized
The experimental rig of animal model, including the housing 1 opened for the bottom that sealing is placed on the head of experimental animal 11, described shell
The pressure sensor 2 of pressure in housing 1 can be monitored by being provided with body 1；
The top of described housing 1 is communicated with one end of hydraulic shock pipe 3, the other end and the check valve 4 of hydraulic shock pipe 3
One end be connected, the other end of check valve 4 is connected with one end of hydraulic shock room 5, and the end face of the other end of hydraulic shock room 5 is
It is filled with pressure regulation liquid, hydraulic shock room 5 and is also communicated with for supplementing pressure regulation liquid in elastic membrane 6, hydraulic shock room 5
Liquid supplementation pipe 7, the impact elasticity film 6 of jump bit 8 so that in hydraulic shock room 5 pressure regulation liquid pass through check valve 4 unidirectionally enter
In hydraulic shock pipe 3；
Pressure is also communicated with described housing 1 and maintains pipe 9, pressure maintains to be provided with pressure-regulating valve 10, housing on pipe 9
1 and pressure maintain pipe 9 in full of pressure adjust liquid when, pressure maintain pipe 9 be used for adjustment housings 1 in pressure.
Housing 1 is transparent shell, is easy to observation, and housing 1 is made of glass or transparent plastic, and transparent plastic is preferably
Lucite.
Elastic membrane 6 is made of elastomeric material.
Pressure regulation liquid is synthetic cerebrospinal fluid or physiological saline, and the preferably cerebrospinal fluid with experimental animal 11 is closer artificial
Cerebrospinal fluid.
Hydraulic shock room 5 is arranged in fixed seat 12, is easy to preferably apply impulsive force.
The course of work of the present utility model is as described below：
Experimental rig of the present utility model is in use, remove one piece of skull on the head of experimental animal 11, by gluing etc.
The bottom end seal that transparent housing 1 is opened is fixed on the head of experimental animal 11 by mode, covers the head of experimental animal 11 and removes
The part of skull so that housing 1 is internally formed a sealed cavity, then maintains pipe 9 to inject people into housing 1 by pressure
Make and synthetic cerebrospinal fluid is also filled with cerebrospinal fluid, hydraulic shock pipe 3 and hydraulic shock room 5, keep the pressure in intracranial pressure and housing 1
Dynamic balance.
By impacting the elastic membrane 6 of the end face of hammering blow hydraulic shock room 5, impact strength is controlled, a series of impacts are designed strong
The experiment of degree or number of shocks, for simulating brain trauma, in whole impact process, is maintained in the adjustment housings 1 of pipe 9 by pressure
The pressure in portion so that the pressure inside housing 1 remains balance with intracranial pressure, to ensure the brain tissue constant volume of encephalic, no
Expansion.
After the completion of being impacted according to default experimental condition, set a series of decompression rates according to test requirements document and tested,
Pipe 9 is maintained to carry out having with controlling decompression by pressure, the influence caused under test different condition to brain tissue.
Claims (7)
1. a kind of experimental rig that animal model is depressurized for brain trauma controlling, including it is placed on experimental animal for sealing
(11) housing (1) that the bottom on head is opened, it is characterised in that：Being provided with described housing (1) can monitor in housing (1)
The pressure sensor (2) of pressure；
Be communicated with one end of hydraulic shock pipe (3) at the top of described housing (1), the other end of hydraulic shock pipe (3) with it is unidirectional
One end of valve (4) is connected, and the other end of check valve (4) is connected with the one end of hydraulic shock room (5), hydraulic shock room (5) it is another
The end face of one end is that pressure regulation liquid is filled with elastic membrane (6), hydraulic shock room (5), and hydraulic shock room is also communicated with (5)
The liquid supplementation pipe (7) of liquid, jump bit (8) impact elasticity film (6) so that the pressure in hydraulic shock room (5) are adjusted for supplementing pressure
Power adjusts liquid and unidirectionally entered by check valve (4) in hydraulic shock pipe (3)；
Pressure is also communicated with described housing (1) and maintains pipe (9), pressure maintains to be provided with pressure-regulating valve (10) on pipe (9),
When housing (1) and pressure maintain to adjust liquid full of pressure in pipe (9), pressure maintains the pressure that pipe (9) is used in adjustment housings (1)
Power.
2. experimental rig as claimed in claim 1, it is characterised in that：Described housing (1) is transparent shell.
3. experimental rig as claimed in claim 2, it is characterised in that：Described housing (1) uses glass or transparent plastic
It is made.
4. experimental rig as claimed in claim 3, it is characterised in that：Described transparent plastic is lucite.
5. experimental rig as claimed in claim 1, it is characterised in that：Described elastic membrane (6) is made of elastomeric material.
6. experimental rig as claimed in claim 1, it is characterised in that：Described pressure regulation liquid is synthetic cerebrospinal fluid or physiology
Salt solution.
7. experimental rig as claimed in claim 1, it is characterised in that：Described hydraulic shock room (5) is arranged on fixed seat
(12) on.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621041652.0U CN206355178U (en) | 2016-09-07 | 2016-09-07 | A kind of experimental rig that animal model is depressurized for brain trauma controlling |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621041652.0U CN206355178U (en) | 2016-09-07 | 2016-09-07 | A kind of experimental rig that animal model is depressurized for brain trauma controlling |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206355178U true CN206355178U (en) | 2017-07-28 |
Family
ID=59369307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621041652.0U Expired - Fee Related CN206355178U (en) | 2016-09-07 | 2016-09-07 | A kind of experimental rig that animal model is depressurized for brain trauma controlling |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206355178U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108158690A (en) * | 2017-12-12 | 2018-06-15 | 河北医科大学第二医院 | Rat hydraulic shock craniocerebral injury equipment and experimental method |
| CN110063809A (en) * | 2019-04-01 | 2019-07-30 | 王春晖 | A kind of shock tube experiment device hurt for simulating animal skull brain pact |
-
2016
- 2016-09-07 CN CN201621041652.0U patent/CN206355178U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108158690A (en) * | 2017-12-12 | 2018-06-15 | 河北医科大学第二医院 | Rat hydraulic shock craniocerebral injury equipment and experimental method |
| CN108158690B (en) * | 2017-12-12 | 2024-03-15 | 河北医科大学第二医院 | Rat hydraulic impact craniocerebral injury equipment and experimental method |
| CN110063809A (en) * | 2019-04-01 | 2019-07-30 | 王春晖 | A kind of shock tube experiment device hurt for simulating animal skull brain pact |
| CN110063809B (en) * | 2019-04-01 | 2023-11-24 | 王春晖 | Shock tube experimental device for simulating animal craniocerebral impact injury |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170728 Termination date: 20180907 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |