CN206252516U - Quantitative determination ovulation device - Google Patents

Quantitative determination ovulation device Download PDF

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Publication number
CN206252516U
CN206252516U CN201620861782.2U CN201620861782U CN206252516U CN 206252516 U CN206252516 U CN 206252516U CN 201620861782 U CN201620861782 U CN 201620861782U CN 206252516 U CN206252516 U CN 206252516U
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module
data
ovulation
quantitative determination
saliva
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CN201620861782.2U
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刘钢
黄金麟
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Measurement (shanghai) Medical Technology Co Ltd
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Measurement (shanghai) Medical Technology Co Ltd
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Abstract

The utility model discloses a kind of quantitative determination ovulation device, including saliva collection module, image capture module, data transmission module and power module, it is characterised in that the saliva collection module is used to gather saliva;Described image acquisition module is used to gather the view data of saliva crystallization, including miniature microscope equipment;The data transmission module is used to carry out the data transfer that image capture module is gathered to external equipment APP modules the treatment and statistical analysis of data;The power module is used to be powered to described image acquisition module and data transmission module.Present apparatus simple operation, efficient, measuring accuracy is high, can accurately extrapolate the ovulation period in ten a few houres.

Description

Quantitative determination ovulation device
Technical field
The utility model is related to medical apparatus detection field, more particularly to a kind of quantitative determination ovulation device.
Background technology
From the point of view of in current prior art, the detailed mechanism and details of human ovulation are also not very clear.But around ovulation, body The feedback regulation formed between the hormones such as interior FSH, LH, estrogen and the gonadotropin-releasing hormone (GRH) by hypothalamus secretion is anti- Should, cause preovulatory hormonal readiness regular and the change of fierceness, it is the inducement that corpus luteum is formed after ovulation is completed and ovulated. It is observed that being played an important role to the generation ovulated to three hormone peak values:First estrogen peak value occurs, induction GnRH releases Increase, thus trigger LH, FSH and almost synchronously reach secretion peak value.During induced ovulation occurs, FSH and LH must be assisted Same-action, only a certain proportion of FSH and LH cooperates with mutually ability effectively induced ovulation, when LH induction ovulations are used alone, ovum Whole ruptures are used a certain proportion of FSH and LH to coordinate when inducing ovulation by the ovarian follicle that nest has been raised, only ripe ovum Bubble just rupture ovulation.
Monitoring ovary ovulation may be used to lower indirect method and be monitored.
(1)Basal body temperature monitoring:Body temperature when basal body temperature refers to early morning inertia, row relatively low always in preovulatory phase Substantially increase about 0.2~0.5 DEG C after ovum, be continued until menstruation.Though easy to be economical, accuracy is poor.
(2)Ovulation prediction is monitored:In the first half of menstrual cycle, uterine neck does not secrete mucus, and vulva is also very dry.Hereafter The a small amount of sticky and opaque mucus of uterine neck secretion.Before will occurring to ovulation, with the appearance on estrogen peak, Ovulation prediction becomes Obtain thin, transparent, limpid, amount also increases, referred to as fertility type mucus.Troublesome poeration.
(3) test paper method:The test paper for having and surveying and ovulate is sold on the market, can buy self testing.Test paper is placed on oneself In urine, if two red lines occurs in " wicket " of test paper, explanation will ovulate.This method needs continuous several times to detect.But Disturbing factor is more, can qualitative or Quasi-quantitative measurement.
(4)Ultrasonoscopy is monitored(B ultrasonic)
It is general to start monitoring in the 10th day menstrual cycle, the change of FD is observed, in the FD of preovulatory 4 days Averagely about increase 3mm daily, in preovulatory follicle maturation about 17~25mm, ovarian follicle disappears after ovulation, and continuous monitoring is visible in ovulation Preceding ovarian follicle is constantly grown up, and when maximum ovarian follicle disappears, points out to ovulate.The method reliability, but continuous monitoring is needed, expense Height, it is time-consuming.
(5)Saliva ovulation detector
Scientific research finds that now the physical chemistry of saliva can be influenceed and change by estrogen, salt content With some enzyme materials also in change.Be can be seen that by ultramicroscopic observation, crystal habit and its cervical mucus of saliva Crystal habit is very much like, shows the pattern of a kind of similar fern or plant leaf blade channels and collaterals, this fernlike crystal image It is general to start appearance at preovulatory 2-3 days, it is the most clear to ovulation period.Gradually crushed after ovulation, dissolving, until be changed into spot Dot pattern.Therefore, the products based on saliva detection all in the market are in accordance with above-mentioned principle, by oneself saliva The observation of crystallization, oneself is visually observed and the general onset of ovulation for judging tested person and the non-onset of ovulation.But due to being by seeing Oneself is examined to visually observe, without any quantitative target, so influenceed by subjective eyesight and microscopical resolution ratio, and The interference of the factors such as the optics of environment cannot be excluded, results contrast is obscured, and only can probably extrapolate measured substantially Ovulation situation, extrapolates and be would be possible within couple of days ovulation, but cannot determine that measured is ovulated the specific time, and this is to keeping away Had little significance for the pregnant and women that becomes pregnant.
Detection method or device for more than, there is the defect of its own, therefore, urgent need is a kind of easy to detect, accurately Degree ovulation detecting device again higher.
Utility model content
To solve the above problems, the utility model provides a kind of portable, efficient, accuracy detection means higher, The ovulation period in 24 hours can accurately be extrapolated.
The purpose of this utility model is achieved through the following technical solutions:
A kind of quantitative determination ovulation device, including saliva collection module, image capture module, data transmission module and power supply Module, the saliva collection module is used to gather saliva;
Described image acquisition module is used to gather the view data of saliva crystallization, including miniature microscope equipment;
The data transmission module is used to carry out data transfer to the external equipment APP modules that image capture module is gathered The treatment and statistical analysis of data;
The power module is used to be powered to described image acquisition module and data transmission module.
Further, above-mentioned saliva collection module includes micro fluidic device, and the micro fluidic device is by two panels PDMA resins It is bonded, including injection port, microchannel and chamber.
Further, above-mentioned image capture module also includes data memory module and signal processing module, and the data are deposited Storage module is used to store the data signal of miniature microscope equipment output;The signal processing module is exported to miniature microscope equipment Data signal is processed and exported to digital data transmission module.
Further, above-mentioned miniature microscope equipment is a miniature Laser Scanning Confocal Microscope, including light emitting diode, lens group Part, photoelectric detector and chip.
Further, above-mentioned data transmission module is connected in wirelessly or non-wirelessly form with external equipment APP modules.
Further, above-mentioned data transmission module includes bluetooth module, wireless connection external equipment APP modules.
Further, above-mentioned quantitative determination ovulation device also includes temperature collect module, and the temperature collect module includes Temperature sensor, the temperature data of the temperature collect module collection is transmitted to external equipment APP moulds by data transmission module Block.
Further, above-mentioned quantitative determination ovulation device is flat cuboid, square or cylinder, the quantitative inspection Surveying ovulation device also includes housing main body and housing cove.The beneficial effects of the utility model are:Arranged in human body according to saliva Ovum phase and the difference of non-onset of ovulation saliva crystal habit, the collection based on saliva crystallographic image data and the data to gathering are set up Algorithm model and standard curve, can be according to the ovulation period of the personal data accurate detection tester of tester;In addition combined with The collection of tester's temperature data simultaneously sets up algorithm model and standard curve, further increases the ovulation period of tester Accuracy.Present apparatus small volume and less weight, it is moderate, it is easy to carry, can be repeatedly detected, it is easy to tester's self testing.
Brief description of the drawings
Fig. 1 the utility model embodiments quantitative determination ovulation apparatus structure schematic diagram;
Fig. 2 the utility model embodiments quantitative determination ovulation device schematic flow sheet;
Fig. 3 the utility model embodiment saliva collecting device schematic diagrames;
The saliva aspect graph of Fig. 4 different times.
1. housing main body;2. housing cove;3. saliva collecting device;30. substrates;31. injection ports;32. microchannels; 33. chambers;4. temperature sensor.
Specific embodiment
Principle of the present utility model and design are described further with specific embodiment below in conjunction with the accompanying drawings:
As shown in figures 1 and 3, a kind of quantitative determination ovulation device, including housing main body 1, housing cove 2, and part is embedding Enter the saliva collecting device 3 in shell 1(Grafting), the saliva collecting device 3 is by two panels PDMA resins(Substrate)Bonding and Into micro fluidic device, including substrate 30, injection port 31, microchannel 32 and chamber 33;
As shown in Fig. 2 housing main body 1 in be provided with for gather view data figure acquisition module, for gathering saliva The temperature collect module of temperature data, data transmission module and power module, the data transmission module is by figure acquisition module The data transfer gathered with temperature collect module to external equipment APP modules, the data transmission module includes bluetooth module, with Outside APP modules wireless connection, the external equipment can be the intelligent terminals such as mobile phone or computer;The figure acquisition module bag Include the miniature microscope equipment and signal processing module being made up of light emitting diode, lens assembly, photoelectric detector and chip etc., institute Stating signal processing module can be processed the data signal of miniature microscope equipment output;The temperature collect module includes setting In the temperature sensor 4 in chamber 33;The power module is used for figure acquisition module, temperature collect module and data transfer Module for power supply, can be used battery as the power module of the present apparatus, and battery case is button cell, it is also possible in the reserved charging in end Port, configuration charging base completes charge function.
When using, by size about 8-20 mm wides, 3-5 centimetres, the micro fluidic device placement of about 3--15 millimeters of thickness are about In tester oral cavity, about 5-30 seconds are placed, using capillary theory, the saliva of collection is entered in a subtle way by injection port Circulation road, reaches chamber, gathers the saliva of about several hectolambdas, takes out afterwards, dries naturally, the time of one minute or so, saliva Condense.The utility model can also use other commercially available saliva collecting devices, and other devices are used cooperatively with the utility model. The utility model saliva collecting device, due to the detection for same tester's Salivary Parameters, can soak the device clear water Bubble 1-2 minutes, reuses after drying, and can reuse about 3000 times, greatly reduces cost.
Gather the view data of saliva crystallization and carry out analog-to-digital conversion by miniature microscope equipment and produce image digital signal, Digital data transmission is carried out after the amplification of signal, demodulation, filtering and buffering, modulation treatment by number successively to signal processing module Exporting outside APP modules according to transport module carries out the treatment and statistical analysis of data.
Need to carry out two months deep learnings in early stage, that is, user needs continuously to measure the bimestrial time, often Its detection 1-3 times, records testing result at that time, and carries out statistical analysis to the data for gathering by software systems, sets up personalized Model and algorithm, according to data, model and algorithm is obtained, comprehensively for the specific data of each tester, to the row of tester Ovum situation is precisely detected and is judged that data according to quantization etc. detect the specific time of ovulation.By unsupervised depth Degree study, only needs the distribution character of estimated data or data is polymerized into certain number of a few classes, saliva form can be divided into gas Bubble, point-like, circle, semicircle, several classifications such as ellipse, strip, zigzag and irregular shape, will be extracted by APP To figure signal carry out classification analysis automatically, it can be deduced that the time result of ovulation.
As shown in figure 4, the saliva form of different times has following change:(One)The onset of ovulation:Image is in the sheep of intensive intersection Dentation(Pteridophyte is lobate), about 8~24 hours, sexual life possibility of becoming pregnant was maximum.(Two)Preovulatory phase:Image is in fern shape (Pteridophyte is lobate)Mix with spot air bubble-shaped, prompt for being in about 3~4 days before or after the onset of ovulation, sexual life is possible to Become pregnant.(Three)Safe period:Image is in mottled or air bubble-shaped, is the non-onset of ovulation.
At the same time, the temperature signal of the saliva that the temperature sensor for using cooperatively together will be gathered passes through data transfer mould Block exports to external equipment APP modules the treatment and statistical analysis for carrying out data, similarly, by the continuous bimestrial depth of early stage Degree study, sets up personalized model and algorithm, sets up corresponding body temperature standard curve.Temperature sensor can be arranged on saliva receipts In acquisition means.
To detect that the temperature curve for obtaining is combined with view data, the degree of accuracy of judgement can be improved, 24h makes in advance Prediction, highest can shift to an earlier date 5h and be predicted, and substantially increase the accuracy of detection.
In addition, it is to be understood that for those of ordinary skills, can according to the technical solution of the utility model and its Inventive concept is subject to equivalent or change, and the right that all these changes or replacement should all belong to appended by the utility model will The protection domain asked.

Claims (10)

1. a kind of quantitative determination ovulation device, including saliva collection module, image capture module, data transmission module and power supply mould Block, it is characterised in that the saliva collection module is used to gather saliva;
Described image acquisition module is used to gather the view data of saliva crystallization, including miniature microscope equipment;
The data transmission module is used to for data transfer to the external equipment APP modules that image capture module is gathered to carry out data Treatment and statistical analysis;
The power module is used to be powered to described image acquisition module and data transmission module.
2. quantitative determination according to claim 1 ovulation device, it is characterised in that the saliva collection module includes miniflow Control device, the micro fluidic device is formed by two panels PDMA resin-bondings, including injection port, microchannel and chamber.
3. quantitative determination according to claim 1 ovulation device, it is characterised in that described image acquisition module also includes number According to memory module and signal processing module, the data memory module is used to store the data signal of miniature microscope equipment output; The signal processing module is processed and exported to data transmission module to the data signal that miniature microscope equipment is exported.
4. quantitative determination according to claim 2 ovulation device, it is characterised in that described image acquisition module also includes number According to memory module and signal processing module, the data memory module is used to store the data signal of miniature microscope equipment output; The signal processing module is processed and exported to data transmission module to the data signal that miniature microscope equipment is exported.
5. the quantitative determination ovulation device according to claim 1-4 any claims, it is characterised in that described miniature aobvious Microdevice is a miniature Laser Scanning Confocal Microscope, including light emitting diode, lens assembly, photoelectric detector and chip.
6. the quantitative determination ovulation device according to claim 1-4 any claims, it is characterised in that the data are passed Defeated module includes bluetooth module, wireless connection external equipment APP modules.
7. according to claim 5 any claim quantitative determination ovulation device, it is characterised in that the data transfer Module includes bluetooth module, wireless connection external equipment APP modules.
8. according to claim 1-4 any claims quantitative determination ovulation device, it is characterised in that the quantitative inspection Surveying ovulation device also includes temperature collect module, and the temperature collect module includes temperature sensor, the temperature collect module The temperature data of collection is transmitted to external equipment APP modules by data transmission module.
9. quantitative determination according to claim 6 ovulation device, it is characterised in that the quantitative determination ovulation device is also wrapped Temperature collect module is included, the temperature collect module includes temperature sensor, the temperature data of the temperature collect module collection Transmitted to external equipment APP modules by data transmission module.
10. according to any claim of claim 1-4,7 or 9 quantitative determination ovulation device, it is characterised in that it is described Quantitative determination ovulation device is flat cuboid, square or cylinder, and the quantitative determination ovulation device also includes shell Main body and housing cove.
CN201620861782.2U 2016-08-10 2016-08-10 Quantitative determination ovulation device Active CN206252516U (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107714096A (en) * 2016-08-10 2018-02-23 量准(上海)医疗科技有限公司 A kind of quantitative detection ovulation device and detection method
TWI701640B (en) * 2019-04-26 2020-08-11 林渝宸 Ovulation prediction method based on saliva crystallization

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107714096A (en) * 2016-08-10 2018-02-23 量准(上海)医疗科技有限公司 A kind of quantitative detection ovulation device and detection method
TWI701640B (en) * 2019-04-26 2020-08-11 林渝宸 Ovulation prediction method based on saliva crystallization

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