CN206080497U - Attached formula cancer cell abnormal temperature probe of skin - Google Patents
Attached formula cancer cell abnormal temperature probe of skin Download PDFInfo
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- CN206080497U CN206080497U CN201620280385.6U CN201620280385U CN206080497U CN 206080497 U CN206080497 U CN 206080497U CN 201620280385 U CN201620280385 U CN 201620280385U CN 206080497 U CN206080497 U CN 206080497U
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0271—Thermal or temperature sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/029—Humidity sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6832—Means for maintaining contact with the body using adhesives
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Abstract
The utility model belongs to the technical field of human parameter measures, a attached formula cancer cell abnormal temperature probe of skin is proposed, this probe contains attached formula body surface physiological parameters measuring device, and the device includes: flexible base member, temperature, measurement human parameter's sensor, and adhesion layer. The utility model discloses structure to the adhesion layer is improved, and the hydrogel layer who has the fretwork shape through the selection makes as the adhesion layer measuring device can closely combine with the measuring point to solved because sluggish the change and unsafe problem of measurement that heat capacity that the adhesion layer material has itself was brought, still improved attached formula cancer cell abnormal temperature probe of skin's lasting measurement capability. This probe can be attached on skin and last the monitor as body temperature and use by the continuation to abnormal temperature to producing because of the cancer cell abnormal metabolism surveys.
Description
Technical field
The utility model belongs to human parameters fields of measurement, more particularly to a kind of sticking type human parameters skin attachment formula cancer
Cell abnormal temperature probe.
Background technology
With the continuous advance and development of wearable technology, increasing wearable device product is also following.
How the human parameters such as temperature, the humidity of human body are monitored using wearable technology, so as to for health evaluation and test data are provided, this into
For a demand.
Utility model content
For the measurement of human parameters, the utility model sticking type skin attachment formula cancer cell exception to be disclosed
Temperature probe can be used as a kind of electronic equipment, and with common wearable product, such as earphone, socks, shoe-pad is combined, so as to straight
Connect and be attached to human body surface, so as to be used for it is long-term, constantly monitor the human parameters such as temperature, humidity of human body, be medical diagnosis or
Health evaluation and test provides data.
By taking measurement temperature as an example, for sticking type temperature measuring equipment, an important performance indications are temperature measurement accuracies,
And affect the factor of temperature measurement accuracy a lot.In the research process of applicant, thermometric dress is improved by providing adhesion layer
Put the tightness degree fitted with human body thermometric position.
During using the temperature measuring equipment with adhesion layer, it has been found that the adhesion layer area for using is larger, adhesion
Material is more, can bring impact to the measurement of temperature.Because adhesion layer, with larger thermal capacity, so as to itself can be from body
Table absorbs a number of heat, makes the temperature environment around temperature sensor deviate from real state.Such as temperature rises sharply
During rapid drawdown, human body produce heat absorption or release effects may because affected by adhesion layer and so that temperature sensor is surveyed
The temperature change for obtaining can lag behind actual Temperature changing.
Applicant further found that, under different temperature conditionss, the quantity of perspiration of the precipitation of body surface is different, and this can cause body surface micro-
Humidity under atmosphere is different.That is, when shell temperature is raised, if with perspiring, temperature and humidity will produce association.
The humidity of human body surface is monitored using humidity sensor, sets up single appraisement system, or humidity combines body surface
Temperature information carries out overall merit, becomes the important research direction of human parameters monitoring.In view of the association of shell temperature and humidity,
Individually monitoring shell temperature or humidity are still meaningful, still can solve the problem that the measurement of human parameters and asking for monitoring
Topic, this will embody in the utility model.Certainly, during the human parameters as to sweat is measured,
Special sensing device as perspiration sensor can also be adopted in addition to using humidity sensor, perspiration sensor can be with opposite
The biomarker of object table, such as protein, sodium, lactic acid, protein etc. are detected.
For now, how to be reduced or eliminated due to measured deviation caused by adhesion material thermal capacity, become and urgently solve
Problem certainly.
The utility model proposes a kind of skin attachment formula cancer cell abnormal temperature probe, the probe includes sticking type body
Table physiological parameter measurement mechanism, the measurement apparatus include：Flexible substrate, is provided with conducting part；At least one body surface physiology is joined
Number sensor, is fixed on the first side of the flexible substrate, electrically connects with the conducting part；And adhesion layer, in hollow out shape,
It is distributed in around the body surface physiological parameter sensors.
Preferably, matrix is flexible substrate, but is not excluded for the matrix semi-rigid or rigid material of selection.
Preferably, the body surface physiological parameter sensors are temperature sensor, humidity sensor, Temperature Humidity Sensor, sweat
At least one in liquid sensor.
Preferably, the hollow out shape includes the closed pattern around body surface physiological parameter sensors described at least one.
Preferably, the body surface physiological parameter sensors, including electrically connecting with the conducting part respectively, and at least in part
The temperature sensor surrounded by the closed pattern, and/or humidity sensor, and/or perspiration sensor.
Preferably, the closed pattern is annulus, elliptical ring, Fang Huan, three square rings or irregular ring-shaped.
Preferably, the hollow out shape includes the discrete figure of multistage around body surface physiological parameter sensors described at least one
Case.
Preferably, the body surface physiological parameter sensors, including electrically connecting with the conducting part respectively and at least in part
The temperature sensor surrounded by the multistage discrete pattern, and/or humidity sensor, and/or perspiration sensor.
Preferably, the multistage discrete pattern is annulus, elliptical ring, Fang Huan, three square rings or by camber line line segment and/or line
The irregular discontinuous ring-shaped of Duan Zucheng.
Preferably, the hollow out shape includes the pattern interlaced with the sensor.
Preferably, the sensor is divided into multiple regions by the hollow out shape.
Preferably, each in the plurality of region includes at least one of described sensor.
Preferably, the carrier is gas permeable material.
Preferably, the adhesion layer includes hydrogel.
Preferably, the adhesion layer corresponds to the region of the sensor by hollow out.
Preferably, heat-conducting layer, covers the temperature sensor, and the height of the heat-conducting layer is not less than the adhesion layer.
Preferably, the heat-conducting layer is heat-conducting glue.
Preferably, the heat-conducting glue is a kind of or many in organosilicon heat-conducting glue, epoxy resin, polyurethane adhesive or heat-conducting silicone grease
The combination planted.
Preferably, the heat-conducting glue includes metal packing.
Preferably, adherent layer, the adherent layer is arranged on the adhesion layer.
Preferably, the temperature sensor is thermistor, and the conducting part is printed circuit.
Preferably, the flexible substrate is provided with through hole, and in the lead to the hole site adhered layer and temperature sensor are not provided with.
Preferably, the flexible substrate is X-shaped, and four branches of the X-shaped flexible substrate are relative to the through hole edge
Radial distribution；The sensor is arranged in four branches.
Preferably, the flexible substrate is to be shaped as cover body；The sensor is arranged on the cover body.
Preferably, the hydrogel is temperature sensitive type water gel or photaesthesia type hydrogel or electric sensitive hydrogel.
Preferably, the hollow out is shaped as array configuration.
Preferably, the unit in the array configuration is straight-flanked ring or circular rings.
Preferably, the hollow out is shaped as irregularly shaped, the irregularly shaped matching human body thermometric surface.
Preferably, described device is used to measure the physiological parameter of breast surface.
Preferably, the hollow out shape is used to reduce adhesive layer material volume, and/or the hollow out shape is used to reduce viscous
Attached layer and the area of attachment on thermometric surface.
That is, hollow out shape of the said apparatus by setting adhesion layer, can reduce adhesion layer from External absorbability heat
Amount, avoids impact of the adhesion layer to true measuring environment as far as possible, and this contributes to weakening heat absorption or the release effect that human body is produced
The not accurate enough negative effect of the result measured by related sensor should be caused because being affected by adhesion layer, so as to
Enough improve the accuracy of the human body parameter acquisitions such as temperature, humidity or humiture.
More importantly it is that above-mentioned sticking type body surface physiological parameter skin attachment formula cancer cell abnormal temperature probe can be answered
For skin attachment formula cancer cell abnormal temperature probe.Skin attachment formula cancer cell abnormal temperature probe with the device,
In above-mentioned and some other application scenarios, can be attached at by continuation and continue to monitor instrument on skin and as body temperature and use,
So as to detect to the abnormal temperature produced because of cancer cell abnormal metabolism.
Description of the drawings
In order to be illustrated more clearly that the utility model embodiment or technical scheme of the prior art, below will be to embodiment
Or the accompanying drawing to be used needed for description of the prior art is briefly described, it should be apparent that, drawings in the following description are only
It is some embodiments of the present utility model, for those of ordinary skill in the art, in the premise for not paying creative work
Under, can be with according to these other accompanying drawings of accompanying drawings acquisition；
Figure 1A is a kind of cross-sectional view of the sticking type temperature measuring equipment according to one embodiment of the present utility model；
Figure 1B is that a kind of cross-section structure of the sticking type temperature measuring equipment according to another embodiment of the present utility model is illustrated
Figure；
Fig. 2 is that a kind of cross-section structure of the sticking type temperature measuring equipment according to another embodiment of the present utility model is illustrated
Figure；
Fig. 3 is a kind of structural representation of the sticking type temperature measuring equipment according to another embodiment of the present utility model；
Fig. 4 is according to the temperature change hesitation measurement result figure caused due to adhesive layer material of the present utility model；
Fig. 5 is the sticking type temperature measuring equipment figure with hollow out adhesion layer according to one embodiment of the present utility model；
Fig. 6 is the sticking type temperature measuring equipment figure with hollow out adhesion layer according to another embodiment of the present utility model；
Fig. 7 is the local of the hollow out adhesion layer close-shaped with one-part form according to one embodiment of the present utility model
Figure；
Fig. 8 is the local of the hollow out adhesion layer with multistage discrete pattern according to another embodiment of the present utility model
Figure；
Fig. 9 is the local of the hollow out adhesion layer with straight-flanked ring array pattern according to one embodiment of the present utility model
Figure；
Figure 10 is the hollow out adhesion layer with elliptical ring array pattern according to another embodiment of the present utility model
Local map；
Figure 11 is the Local map of the hollow out adhesion layer with irregular pattern according to one embodiment of the present utility model.
Specific embodiment
In order that those skilled in the art more fully understand the technical scheme in the utility model embodiment, below in conjunction with
Accompanying drawing in the utility model embodiment, is clearly and completely described to the technical scheme in the utility model embodiment, shows
So, described embodiment is only a part of embodiment of the utility model, rather than the embodiment of whole.It is new based on this practicality
Embodiment in type, the every other enforcement that those of ordinary skill in the art are obtained under the premise of creative work is not made
Example, belongs to the scope of the utility model protection.
As previously mentioned, in view of the association of shell temperature and humidity, individually monitoring shell temperature or humidity are still
It is significant, still can solve the problem that the problem of measurement and the monitoring of human parameters.For ease of description, following embodiment mainly with
Human parameters to be measured illustrates each technical scheme of the present utility model for temperature.Because the utility model has used body surface
Temperature and associating that body surface is perspired, then the embodiment of corresponding measurement humidity will not be described in great detail.
In one embodiment, the utility model provides a kind of sticking type temperature measuring equipment, and the temperature measuring equipment includes flexibility
Matrix 101, temperature sensor 102 and adhesion layer 103.
Sensor can be one, or multiple, as long as meeting basic measurement demand.Flexible substrate 101
Can be made by the material with flexible nature, but be not excluded for when matrix needs specific shape using semi-rigid or
Rigid material, as an example, can be realized using flexible PCB, and flexible PCB at least includes following component：
(1) base material：The base material of flexible PCB can select polyimides.In order to ensure comfort level of the human body to base material,
The base material of 25 μ m-thicks can be selected.It is a little hard if necessary to circuit board, the thickness of base material can be increased, such as from the base of 50 μ m-thicks
Material., whereas if needing circuit board a little soft, then base material of 13 μ m-thicks etc. is can select.
(2) transparent adhesive tape of base material：It is divided into two kinds of epoxy resin and polyethylene, base material and transparent adhesive tape thereon are thicker, circuit
Plate is harder.If circuit board has bending than larger region, can select than relatively thin base material and transparent adhesive tape to reduce Copper Foil table
The stress in face, the chance that micro-crack occurs in such Copper Foil is smaller.For such region, lamina can be as far as possible selected.
(3) Copper Foil：It is divided into two kinds of calendering copper and cathode copper.Calendering copper intensity is high, resistant to bending but expensive.Cathode copper
Much, but intensity difference, frangibility are commonly used in the occasion of little bending to low price.The selection of copper thickness will be according to lead
Depending on minimum widith and minimum spacing.Copper Foil is thinner, and accessible minimum widith and spacing are less.In the utility model embodiment
From calendering copper, and ensure that the rolling direction of Copper Foil is consistent with the main bending direction of circuit board.
(4) diaphragm and its transparent adhesive tape：For the scheme in the application, due to there is bending than larger circuit
Plate, from 13 μm of diaphragm.The material of transparent adhesive tape can select epoxy resin and polyethylene both one of, transparent adhesive tape is set
Thickness is 13 μm.
(5) pad coating：Using electronickelling+chemical plating layer gold, the THICKNESS CONTROL of electroless nickel layer at 0.5-2 μm, chemical plating
The THICKNESS CONTROL of layer gold is at 0.05-0.1 μm.
The flexible substrate 101 is internally provided with conducting part 106 (referring to Fig. 3), and the conducting part is at least one printing
Circuit, the printed circuit can have the metal material with excellent conductive performance and bending resistance such as Copper Foil to be made, can be with
Free bend, winding, folding, can require arbitrarily to arrange according to space layout, and arbitrarily move and flexible in three dimensions, from
And reach the integration of components and parts (such as temperature sensor) assembling and wire connection.
In order to the collecting temperature data from human body target, needs are provided with TEMP in sticking type temperature measuring equipment
Device 102, these temperature sensors 102 such as may be used from the surface of object to be measured collecting temperature data at predetermined intervals
Gathered a temperature data per five minutes to arrange, and continuous collecting is for a period of time (such as 10 hours).The temperature of all generations
Data are stored in a portable storage device.Sensor 102 is fixed on the side of flexible substrate, and and flexible substrate
Interior circuit connection.Lasting collection, it is clear that be conducive to monitoring related data in a period of time.
Temperature sensor 102 can be to be realized, for example using the sensor of multiplex pattern, and temperature sensor 102 can
To be realized by thermistor, based on the difference of thermo-sensitive material, thermistor again can as needed using semiconductor temperature-sensitive electricity
Resistance, metal thermo-sensitive resistance and alloy thermal responsive resistance.
In addition, sticking type temperature measuring equipment also includes adhesion layer 103, and the main purpose of adhesion layer 103 is to pass temperature
Sensor is fixed on human body, and referring to Figure 1A, Figure 1B, adhesion layer can be arranged on flexible substrate using various ways.Adhesion layer
Presence and sticking type skin attachment formula cancer cell abnormal temperature probe, the particularly employing of flexible substrate, it is clear that also have
Beneficial to monitoring related data in a period of time.
As shown in Figure 1A, adhesion layer is directly overlayed on temperature sensor 102 and flexible substrate, and this mode has been implemented
Come more convenient, be easy to adhesion layer cutting in the preparation and batch production.
In addition to aforesaid way, referring to Figure 1B, adhesion layer 103 can also be arranged in addition to temperature sensor 102
Other regions, adhesion layer 103 is provided with through hole at the position that installation settings has temperature sensor, so that temperature sensor
Can be arranged in through hole, other regions outside through hole, adhesion layer 103 directly connects with flexible base board 101.
Adhesion layer can be made by the sticking material of various tools, for example, can adopt skin is had compared with
Strongly adherent and can painless detached hydrogel.
The fixed forms such as traditional adhesive tape are replaced with hydrogel layer, the temperature sensor of temperature measuring equipment can be caused more just
Profit, human body surface of closely fitting, so that carrying out heat with being more fully contacted between temperature sensor and the tested area of body surface
Transmission, lifts the certainty of measurement of temperature measuring equipment.
Based on the sticking type temperature measuring equipment of said structure design, preferable beneficial effect can be realized, to measure chest region
As a example by the temperature in domain, respectively using following three kinds of different types of temperature measuring equipments：(1) ordinary electronic formula clinical thermometer (certain company type
Number for MC-246 thermometer product)；(2) temperature sensing device in the present embodiment；(3) intrusive mood blood heat measuring instrument.
By repeatedly measurement, for research object body temperature by above-mentioned three kinds of body temperature skin attachment formula cancer cell abnormal temperature
The measurement result of probe is followed successively by：1) 36.77 DEG C, 2) 36.86 DEG C, 3) 36.90 DEG C.
Using the temperature data measured by intrusive mood blood heat measuring instrument as standard reference data；According to grinding to 100
Study carefully the statistics of the axillaty temperature measurement result of object, ordinary electronic clinical thermometer surveys data positioned at intrusive mood blood heat measuring instrument
Within the error burst of [- 0.97% ,+0.31%] of surveyed temperature data, measurement data relative to standard reference data point
Cloth center is generally within -0.57%.And the temperature sensing device in the present embodiment is surveyed data and is surveyed positioned at intrusive mood blood heat
Amount instrument is surveyed within the error burst of [- 0.19% ,+0.06%] of temperature data, and measurement data is relative to standard reference data
Distribution center generally within -0.08%, the degree of accuracy of its measurement data, hence it is evident that survey data better than ordinary electronic clinical thermometer.
In addition to adhesion layer is set, for the ease of fixing temperature measuring equipment, some fixing devices can be set.Referring to figure
3, to test human breast temperature as a example by, through hole 105 can be set on flexible substrate, the position of through hole 105 be not provided with paste
Layer and temperature sensor.Through hole 105 is used to be socketed nipple or body other protuberances, and to help this is fixed body is installed on
On.Flexible substrate is set to X-shape, and this shape is easy to be pasted onto the breast portion of human body, and the space for taking is less, when
So, in addition to X-shape, flexible substrate is it can also be provided that other common shapes, such as Y shape shape etc..
In order to ensure the accuracy and validity of measurement temperature, referring to Fig. 2, one is covered on temperature sensor 102
Heat-conducting part 104 so that heat-conducting part is higher than adhered layer 103, such that it is able to guarantee, when temperature sensing device is sticked on body, to lead
Hot portion is fully fitted on skin, strengthens the accuracy of heat-transfer effect and sensor senses body temperature.Specifically, heat-conducting part can be with
It is made using various materials with thermal conduction characteristic, such as heat-conducting part can be heat-conducting glue, for carrying out the biography of heat
Lead, heat-conducting glue can be one or more in epoxy resin, organosilicon heat-conducting glue, polyurethane adhesive, heat-conducting silicone grease；It is wherein more excellent
Selection of land, is mixed with the metal dusts such as aluminium powder, copper powder, iron powder in heat-conducting glue, this can strengthen its thermal conductivity.
The temperature measuring equipment of said structure is increased, its thermometric accuracy is further improved, with chest region
As a example by the temperature survey in domain, respectively using following three kinds of different types of temperature measuring equipments：(1) (certain is public for ordinary electronic formula clinical thermometer
The thermometer product of department's model MC-246)；(2) temperature sensing device in the present embodiment；(3) intrusive mood blood heat measurement
Instrument.
It is different by above-mentioned three kinds of body temperature skin attachment formula cancer cell for the body temperature of a certain example research object by repeatedly measurement
The measurement result of normal temperature probe is followed successively by：1) 36.77 DEG C, 2) 36.86 DEG C, 3) 36.90 DEG C.
Using the temperature data measured by intrusive mood blood heat measuring instrument as standard reference data；According to grinding to 100
Study carefully the statistics of the axillaty temperature measurement result of object, ordinary electronic clinical thermometer surveys data positioned at intrusive mood blood heat measuring instrument
Within the error burst of [- 0.97% ,+0.31%] of surveyed temperature data, measurement data relative to standard reference data point
Cloth center is generally within -0.57%.And the temperature sensing device in the present embodiment is surveyed data and is surveyed positioned at intrusive mood blood heat
Amount instrument is surveyed within the error burst of [- 0.10% ,+0.02%] of temperature data, and measurement data is relative to standard reference data
Distribution center generally within -0.04%, the degree of accuracy of its measurement data, hence it is evident that survey data better than ordinary electronic clinical thermometer.
Viscosity is reduced to prevent adhesion layer contamination dust, adherent layer is coated with adhesion layer, adherent layer specifically can be with
For a plastic paper.
Used as a specific embodiment, adhesion layer 103 is made by hydrogel material.Hydrogel material is directly used
In contacting with tissue, the infection of micro-organisms in vitro can be prevented, suppress the loss of body fluid, transmission oxygen to wound, generally
The healing of wound can be promoted.
After hydrogel is transplanted or is expelled to organism, hydrogel is able to maintain that or is embedded in water to body fluid control release
Medicine in gel, it is, in general, that there is two kinds of control release, one kind is to discharge small molecule as gel application thing,
Another kind of situation is that the polymeric substrate containing medicine gradually decomposes, and in this case, drug diffusion enters surrounding environment, by
The biodegradation rate control of material.Sometimes hydrogel loads medicine as micella, and the speed of insoluble drug release is by by adjusting friendship
The chemical composition of connection degree and hydrogel has realized that since particularly progress in Intelligent Hydrogel comes out, the use of hydrogel is more extensive.
Specifically, hydrogel can adopt temperature sensitive type water gel, common temperature sensitive type water gel to include：From
The polypropylene milling aqueous amine gel of sonization, poly- (dihexyl of N, N mono-) acrylamide gel and poly- (N- isopropyls) acrylamide
Hydrogel etc..
In addition, hydrogel can also be using photaesthesia type hydrogel and electric sensitive hydrogel.
In experimentation, if it is found by the applicant that adhesion layer 103 is glued when in use using continuous shape in uniform thickness
Attached layer laminating skin surface, when body temperature changes, adhesion layer can either raise with the reduction of temperature and radiate or inhale
Heat, so as to hinder the temperature change around temperature sensor, this can cause the human body temperature change that temperature sensor senses are arrived stagnant
After actual change, temperature sensing sensitivity is had influence on.Test result shows, the size and adhesion layer of adhesion layer volume (quality)
It is the delayed main factor of impact temperature change with the contact area on thermometric surface.As Fig. 4 actual temperature change with measure
The contrast of temperature variation curve, the sluggishness of temperature change can increase as the change of adhesion layer volume (quality) is big.When using same
The adhesive layer material of sample volume, but using the adhesion layer of different-thickness, find the sluggishness of temperature change with adhesion layer and thermometric
The increase of the contact area on surface (skin) and increase.
In order to solve the above problems, because temperature change hysteresis is because the thermal capacity of adhesive layer material itself causes
, on the premise of not affecting to adhere to firmness, reducing the volume (quality) of adhesive layer material then can greatly reduce due to adhesion
The thermal capacitance of layer material.In addition, adhesion layer is bigger with the contact area on thermometric surface, then the area of heat transfer is bigger, therefore,
The contact area for reducing adhesion layer with thermometric surface is also to improve temperature change hysteresis.Using in both modes at least
A kind of hesitation to temperature improves.
In one embodiment, while ensureing that adhesion is firm, hollow out is carried out to adhesion layer, reduces the material of adhesion layer
With adhesion layer and the contact area on thermometric surface, the adhesion layer after hollow out is in that continuous one-part form is close-shaped in local, and this is closed
Close shape, between thermometric surface and flexible substrate 101 formed local closing space, due to the close-shaped thermal capacitance it is little, and
And contact little with thermometric surface, and local micro climate is formed in closing space, temperature sensor can insusceptibly for the local
Carry out temperature information collection.
In one embodiment, described device can also include that the adhesion layer after humidity sensor, and hollow out is in local
Multistage discrete pattern, multistage discrete pattern surrounds temperature sensor and humidity sensor surrounding, and this set can increase temperature
The opening of the local that Humidity Sensor Array is located, can enable Temperature Humidity Sensor array to collect closest to nature shape
The humiture parameter in body surface microenvironment under state.
In one embodiment, described device can also arrange perspiration sensor to substitute humidity sensor, the sensor
The composition in sweat can be analyzed, more rich data are collected in help, there is provided specialization suggestion, by the way that perspiration sensor is integrated
In one piece of little paster, then it is close on skin, it becomes possible to detect the biomarker that can be shown that your health in sweat,
Such as moisture, electrolyte, sodium, lactic acid, protein.The biomarker collected can be analyzed by default algorithm.One
Aspect can individually evaluate biological condition, it is recognised that when requiring supplementation with moisture, need that how much water drunk, and need to drink pure water
Or sports drink.Even, it can be with early warning heatstroke and hyperkinetic danger.In electrolyte balance detection and water content detection
Outside, the sensor technology can also monitor the pH value of muscular fatigue degree, physical demands level, breathing and skin so can effectively drop
Situations such as knotting in harmonic motion occurs.On the other hand the body temperature situation that can be obtained with combination temperature sensor, temperature and sweat are passed
The appraisement system of sensor composition will carry out strong monitoring to human body situation.
In other embodiment, the adhesion layer after hollow out can be alternately arranging with temperature-humidity sensor.
In the above-described embodiments, temperature sensor, humidity sensor, perspiration sensor, Temperature Humidity Sensor respectively with biography
Lead portion and form electrical connection, which ensure that the individual transmission of the signal that sensor is obtained.
In measurement process, different measurement patterns can be taken into account, in the embodiment corresponding to Fig. 5, flexible substrate quilt
The shape of brassiere is fabricated to, to measure to the temperature at breast, the adhesion layer after hollow out includes：In local in continuous
One-part form is close-shaped, and in another local multistage discrete pattern.Array of temperature sensor and humidity sensor are wrapped
In humiture pattern of different shapes.Pierced pattern can greatly reduce the thermal capacitance of adhesive layer material and act on to local temperature
Affect, the close-shaped of local can also make temperature sensor unaffected using local micro climate is formed in closing space
Ground locally carries out temperature information collection for this；Another enables Temperature Humidity Sensor array locally by multistage discrete pattern
Enough collect the humiture parameter in the body surface microenvironment closest under nature.By the gathered data of two local temperatures
The temperature hysteresis effect that can cause to adhesive layer material is further corrected.
In the embodiment corresponding to Fig. 6, flexible substrate is made into the shape of brassiere, to enter to the temperature at breast
Row measurement, wherein there is 3 groups of Temperature Humidity Sensor arrays, the adhesion layer after hollow out with closed manners be discretely arranged at 3 groups it is warm and humid
Between degree sensor array.When using, adhesion part 1-4 is fitted on the skin at the positions such as breast so that 3 groups of Temperature Humidity Sensors
Array can respectively measure the temperature humidity information of corresponding position.Flexible substrate is made up of gas permeable material, so as to without prejudice to body surface exists
Radiating and moisture evaporation under nature so that Temperature Humidity Sensor array can capture the temperature humidity under nature
Information.
In the corresponding embodiments of Fig. 5-8, adhesion layer after hollow out local in annulus, elliptical ring, straight-flanked ring, three square rings,
Or the irregular ring-shaped being made up of camber line line segment and/or line segment.Above-mentioned adhesion layer be also configured to one-part form it is close-shaped or
Person's multistage discrete pattern, different pierced pattern is arranged on flexible substrate of different shapes, to be adapted to different portions
Position carries out temperature survey.
In the corresponding embodiments of Fig. 9-11, adhesion layer can also be set to the array configuration of certain pattern.Glue in Fig. 9
Attached layer is become the array configuration of straight-flanked ring composition by hollow out, each one group of temperature and moisture sensors of straight-flanked ring inside wrapping, should
Class engraved structure is more suitable for relatively flat thermometric surface, be for example arranged at abdominal belt, wrist strap or headband with to belly, wrist or
Person's head carries out thermometric.
Adhesion layer is become the array configuration of elliptical ring composition by hollow out in Figure 10, each one group of temperature of elliptical ring inside wrapping
And humidity sensor, such sensor is equally applicable for relatively flat thermometric surface, for example, is arranged at abdominal belt, wrist strap or headband
To carry out thermometric to belly, wrist or head.Additionally, oval or circle can engrave more materials relative to square,
Annular is also slightly better than square configuration with the adhesiving effect on thermometric surface.
Adhesion layer becomes semi-open irregularly shaped by hollow out in Figure 11, and the shape can more fit the difference of human body
Thermometric surface, it is micro- that semi-open shape enables to the body surface that Temperature Humidity Sensor array can be collected closest under nature
Humiture parameter in environment.
In other embodiment, adhesion layer array can be the array of pierced pattern of different shapes composition or from
Scattered shape.
In figure, humidity sensor is represented with " rhombus ", and temperature sensor or perspiration sensor are represented with " square ".
For sensor, it surround by pierced pattern, partly surround or with hollow out figure by alternately arranging, can is single
The temperature sensor array that either single humidity sensor or the two combination are formed, can also be and be integrated with temperature and humidity
The Temperature Humidity Sensor of measurement function.
Temperature measuring equipment in above-mentioned some embodiments, also serves as cancer cell thermometer, for detecting, monitoring human body, especially
It is body surface, auxiliary such that it is able to from the index of Temperature changing because of the growth of cancer cell, canceration and issuable temperature anomaly
Helping carries out examination, the health evaluating work of disease (such as cancer).
Particularly, above-described embodiment is more by taking measurement temperature as an example, and some embodiments then combine measurement humidity.As discussed above
Described, above-mentioned each embodiment is to carry out example human parameters skin attachment of the present utility model with the temperature measuring equipment of measurement temperature
Formula cancer cell abnormal temperature probe.Because the utility model has used shell temperature with associating that body surface is perspired, then corresponding
The embodiment of measurement humidity repeat no more, accordingly to measure based on humidity, also no longer go to live in the household of one's in-laws on getting married with reference to the embodiment of measurement temperature
State.
More importantly it is that above-mentioned sticking type body surface physiological parameter skin attachment formula cancer cell abnormal temperature probe can be answered
For skin attachment formula cancer cell abnormal temperature probe.Skin attachment formula cancer cell abnormal temperature probe with the device,
In above-mentioned and some other application scenarios, can be attached at by continuation and continue to monitor instrument on skin and as body temperature and use,
So as to detect to the abnormal temperature produced because of cancer cell abnormal metabolism.
The above, specific embodiment only of the present utility model, but protection domain of the present utility model do not limit to
In this, any those familiar with the art in the technical scope that the utility model is disclosed, the change that can be readily occurred in
Change or replace, all should cover within protection domain of the present utility model.Therefore, protection domain of the present utility model should be with right
The protection domain of requirement is defined.
Claims (25)
1. a kind of skin attachment formula cancer cell abnormal temperature probe, the probe includes sticking type body surface physiological parameter measurement dress
Put, it is characterised in that the measurement apparatus include：Flexible substrate, is provided with conducting part；At least one body surface physiological parameter is sensed
Device, is fixed on the first side of the flexible substrate, electrically connects with the conducting part；And adhesion layer, in hollow out shape, it is distributed in
Around the body surface physiological parameter sensors.
2. skin attachment formula cancer cell abnormal temperature probe according to claim 1, it is characterised in that：The body surface physiology
Parameter sensors are at least one in temperature sensor, humidity sensor, Temperature Humidity Sensor, perspiration sensor.
3. skin attachment formula cancer cell abnormal temperature probe according to claim 1, it is characterised in that：The hollow out shape
Including the closed pattern around body surface physiological parameter sensors described at least one.
4. skin attachment formula cancer cell abnormal temperature probe according to claim 3, it is characterised in that：The body surface physiology
Parameter sensors, including electrically connecting with the conducting part respectively, and the temperature surrounded by the closed pattern at least in part is passed
Sensor, and/or humidity sensor, and/or perspiration sensor.
5. skin attachment formula cancer cell abnormal temperature probe according to claim 3, it is characterised in that：The closed pattern
For annulus, elliptical ring, Fang Huan, three square rings or irregular ring-shaped.
6. skin attachment formula cancer cell abnormal temperature probe according to claim 1, it is characterised in that：The hollow out shape
Including the multistage discrete pattern around body surface physiological parameter sensors described at least one.
7. skin attachment formula cancer cell abnormal temperature probe according to claim 6, it is characterised in that：The body surface physiology
Parameter sensors, including the temperature for electrically connecting with the conducting part respectively and surrounded by the multistage discrete pattern at least in part
Degree sensor, and/or humidity sensor, and/or perspiration sensor.
8. skin attachment formula cancer cell abnormal temperature probe according to claim 6, it is characterised in that：The multistage is discrete
Pattern is annulus, elliptical ring, Fang Huan, three square rings or the irregular discontinuous ring-shaped being made up of line segment.
9. skin attachment formula cancer cell abnormal temperature probe according to claim 1, it is characterised in that：The hollow out shape
Comprising the pattern interlaced with the sensor.
10. skin attachment formula cancer cell abnormal temperature probe according to claim 1, it is characterised in that：The hollow out shape
The sensor is divided into multiple regions by shape.
11. skin attachment formula cancer cell abnormal temperature probes according to claim 10, it is characterised in that：The plurality of area
Each in domain includes at least one of described sensor.
The 12. skin attachment formula cancer cell abnormal temperature probes according to any one of claim 1-11, it is characterised in that：Institute
Flexible substrate is stated for gas permeable material.
The 13. skin attachment formula cancer cell abnormal temperature probes according to any one of claim 1-11, it is characterised in that：Institute
Adhesion layer is stated including hydrogel.
14. skin attachment formula cancer cell abnormal temperature probes according to claim 1, it is characterised in that：
The adhesion layer corresponds to the region of the sensor by hollow out.
15. skin attachment formula cancer cell abnormal temperature probes according to claim 2, it is characterised in that：
Heat-conducting layer, covers the temperature sensor, and the height of the heat-conducting layer is not less than the adhesion layer.
16. skin attachment formula cancer cell abnormal temperature probes according to claim 15, it is characterised in that：
The heat-conducting layer is heat-conducting glue.
17. skin attachment formula cancer cell abnormal temperature probes according to claim 1, it is characterised in that：
Adherent layer, the adherent layer is arranged on the adhesion layer.
18. skin attachment formula cancer cell abnormal temperature probes according to claim 2, it is characterised in that：
The temperature sensor is thermistor, and the conducting part is printed circuit.
19. skin attachment formula cancer cell abnormal temperature probes according to claim 1, it is characterised in that：
The flexible substrate is provided with through hole, and flexible substrate surface arranges adhesion layer and temperature sensor.
20. skin attachment formula cancer cell abnormal temperature probes according to claim 19, it is characterised in that：
The flexible substrate is X-shaped, and four branches of the X-shaped flexible substrate are radially distributed relative to the through hole；Institute
State sensor to be arranged in four branches.
21. skin attachment formula cancer cell abnormal temperature probes according to claim 1, it is characterised in that：
The flexible substrate is shaped as cover body；The sensor is arranged on the cover body.
22. skin attachment formula cancer cell abnormal temperature probes according to claim 13, it is characterised in that：
The hydrogel is temperature sensitive type water gel or photaesthesia type hydrogel or electric sensitive hydrogel.
23. skin attachment formula cancer cell abnormal temperature probes according to claim 1, it is characterised in that：The hollow out shape
Shape is array configuration.
24. skin attachment formula cancer cell abnormal temperature probes according to claim 23, it is characterised in that：The array shape
Unit in shape is straight-flanked ring or circular rings.
25. skin attachment formula cancer cell abnormal temperature probes according to claim 1, it is characterised in that：The hollow out shape
Shape is irregularly shaped, the irregularly shaped matching human body thermometric surface.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2015109635531 | 2015-12-18 | ||
| CN201510963553 | 2015-12-18 |
Publications (1)
| Publication Number | Publication Date |
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| CN206080497U true CN206080497U (en) | 2017-04-12 |
Family
ID=56308489
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620279918.9U Expired - Fee Related CN205988282U (en) | 2015-12-18 | 2016-04-06 | Physiological parameter measurement mechanism |
| CN201610210678.1A Pending CN105662361A (en) | 2015-12-18 | 2016-04-06 | Continuous body temperature monitoring instrument |
| CN201620280385.6U Active CN206080497U (en) | 2015-12-18 | 2016-04-06 | Attached formula cancer cell abnormal temperature probe of skin |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201620279918.9U Expired - Fee Related CN205988282U (en) | 2015-12-18 | 2016-04-06 | Physiological parameter measurement mechanism |
| CN201610210678.1A Pending CN105662361A (en) | 2015-12-18 | 2016-04-06 | Continuous body temperature monitoring instrument |
Country Status (2)
| Country | Link |
|---|---|
| CN (3) | CN205988282U (en) |
| WO (1) | WO2017101713A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113973494A (en) * | 2019-05-23 | 2022-01-25 | 活跃骨科技术服务有限公司 | Sensor layer for determining a temperature profile on a skin surface, auxiliary means for wearing on a skin surface, method for producing an auxiliary means and method for determining a relative temperature difference on a skin surface |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN205988282U (en) * | 2015-12-18 | 2017-03-01 | 上海温尔信息科技有限公司 | Physiological parameter measurement mechanism |
| CN106137146A (en) * | 2016-08-19 | 2016-11-23 | 浙江隆泰医疗科技股份有限公司 | Adhesive type electric body-temperature pastes |
| WO2018133080A1 (en) * | 2017-01-22 | 2018-07-26 | 上海温尔信息科技有限公司 | Temperature analysis method and device |
| CN108078548A (en) * | 2018-01-22 | 2018-05-29 | 哈尔滨海外电气系统工程总包有限公司 | Physiological parameter detecting device and brassiere |
| CN108720814A (en) * | 2018-08-13 | 2018-11-02 | 脱浩东 | A kind of Breast health remote supervision system and method |
| CN111000534A (en) * | 2019-12-03 | 2020-04-14 | 南通大学 | Wearable multifunctional human body surface temperature and humidity monitoring equipment and early warning method |
| CN111870274A (en) * | 2020-03-19 | 2020-11-03 | 万佳睿 | Bluetooth auscultation device |
| CN112834078A (en) * | 2020-12-30 | 2021-05-25 | 深圳市联影高端医疗装备创新研究院 | Body temperature measuring device and method |
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| US5301681A (en) * | 1991-09-27 | 1994-04-12 | Deban Abdou F | Device for detecting cancerous and precancerous conditions in a breast |
| US20050117626A1 (en) * | 2001-11-20 | 2005-06-02 | Isamu Kobayashi | Thermometer |
| WO2007038607A2 (en) * | 2005-09-27 | 2007-04-05 | Telzuit Technologies, Llc | Apparatus and method for monitoring patients |
| US9014778B2 (en) * | 2008-06-24 | 2015-04-21 | Biosense Webster, Inc. | Disposable patch and reusable sensor assembly for use in medical device localization and mapping systems |
| JP5476114B2 (en) * | 2009-12-18 | 2014-04-23 | 東京エレクトロン株式会社 | Temperature measuring device |
| WO2012125425A2 (en) * | 2011-03-11 | 2012-09-20 | Proteus Biomedical, Inc. | Wearable personal body associated device with various physical configurations |
| US9782082B2 (en) * | 2012-11-01 | 2017-10-10 | Blue Spark Technologies, Inc. | Body temperature logging patch |
| TWM480991U (en) * | 2013-12-05 | 2014-07-01 | Yofa Biotechnology Co Ltd | Patch-type temperature measuring apparatus |
| CN203736170U (en) * | 2014-01-14 | 2014-07-30 | 珠海爱晟医疗科技有限公司 | Skin body temperature probe |
| CN104257356B (en) * | 2014-09-16 | 2016-08-31 | 苏州能斯达电子科技有限公司 | A kind of flexible temp-sensitive sensor and Thermometer System based on this sensor |
| CN204881887U (en) * | 2014-11-04 | 2015-12-16 | 梁于阳 | Temperature measurement sensor module |
| CN104523245A (en) * | 2015-01-07 | 2015-04-22 | 何筱峰 | Passive RFID wireless body temperature detection patch and system |
| CN204394477U (en) * | 2015-01-08 | 2015-06-17 | 江波涛 | A kind of body surface measurement device and measuring system |
| CN205072836U (en) * | 2015-08-28 | 2016-03-09 | 上海温尔信息科技有限公司 | Temperature sensing device and temperature sensing underwear |
| CN105105722A (en) * | 2015-08-28 | 2015-12-02 | 上海温尔信息科技有限公司 | Temperature sensing device and temperature sensing underwear |
| CN205988282U (en) * | 2015-12-18 | 2017-03-01 | 上海温尔信息科技有限公司 | Physiological parameter measurement mechanism |
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2016
- 2016-04-06 CN CN201620279918.9U patent/CN205988282U/en not_active Expired - Fee Related
- 2016-04-06 CN CN201610210678.1A patent/CN105662361A/en active Pending
- 2016-04-06 CN CN201620280385.6U patent/CN206080497U/en active Active
- 2016-12-06 WO PCT/CN2016/108724 patent/WO2017101713A1/en active Application Filing
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113973494A (en) * | 2019-05-23 | 2022-01-25 | 活跃骨科技术服务有限公司 | Sensor layer for determining a temperature profile on a skin surface, auxiliary means for wearing on a skin surface, method for producing an auxiliary means and method for determining a relative temperature difference on a skin surface |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105662361A (en) | 2016-06-15 |
| CN205988282U (en) | 2017-03-01 |
| WO2017101713A1 (en) | 2017-06-22 |
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Effective date of registration: 20201113 Address after: Room 109, 1 / F, building 7, No. 204, Huyi Road, Jiading District, Shanghai, 201802 Patentee after: Shanghai rhythm Biotechnology Co.,Ltd. Address before: 201802 room 5, building 1690, 3176, Jia Hao Road, Shanghai, Jiading District Patentee before: WELL DIAGNOSTICS TECHNOLOGY (INTERNATIONAL) Corp. |