CN205761069U - A kind of three hole coaxial-types dual breast grain generating means - Google Patents
A kind of three hole coaxial-types dual breast grain generating means Download PDFInfo
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- CN205761069U CN205761069U CN201620691682.XU CN201620691682U CN205761069U CN 205761069 U CN205761069 U CN 205761069U CN 201620691682 U CN201620691682 U CN 201620691682U CN 205761069 U CN205761069 U CN 205761069U
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Abstract
The utility model discloses a kind of three hole coaxial-types dual breast grain generating means, this device includes generator body and three-phase pipeline, it is equipped with by boss, shrinkage pool interference seal between each parts of generator body, three-phase pipeline inserts generator body and forms coaxial device, injects solution system in a device and produces dual breast grain.This three holes coaxial-type dual breast grain generating means uses coaxial shear mode, is successfully prepared the dual breast grain of internal diameter 800 μm ~ 1000 μm, the wall thickness 50 μm ~ 300 monodispersed W/O/W of μm.By changing the size of three-phase pipeline, it is possible to prepare the dual breast grain of internal diameter 200 μm ~ 3000 μm；By changing the hydrophilicity and hydrophobicity of three-phase pipeline, additionally it is possible to prepare the double emulsion of Water-In-Oil bag oil；Simple to operate applied widely, easy cleaning, control accuracy is high, can effectively solve current emulsion micropackaging and send out and prepare diameter in grade polymer microballoon, the uncontrollable problem of wall thickness.
Description
Technical field
This utility model belongs to microfluidic applications field, is specifically related to a kind of three hole coaxial-types dual breast grain generating means.
Background technology
In ICF studies, frequently with polymer microballoon as pellet fuel container, the diameter of polymer microballoon is from hundreds of micro-
Rice to several millimeters.Generally use emulsion method to prepare polymer microballoon, the most first generate the double emulsion of W/O/W, then remove having of O phase
Machine solvent, obtains the polymer spherical shell of solidification, and polymer microballoon diameter is typically hundreds of micron extremely several millimeters.Conventional preparation is double
The method of gravity emulsion has mechanical mixing method and microfluidic control method.Double emulsion distribution of sizes width prepared by mechanical mixing method, examination
Agent usage amount is big, is not suitable for accurate control.Micro-fluidic technologies is a kind of side preparing multiple emulsion of the development nineties in last century
Method, the mode producing drop according to micro-fluidic technologies can be divided into T-shaped shearing, parallel shearing and converge shearing microfluid dress
Put.Chun-Xia Zhao and Minseok Seo etc. have studied T-shaped shearing in two-phase fluid, parallel shearing, converges shearing, film breast
The mechanism of action of the modes such as change, analyzes the impact of phase parameter, has obtained the mono-breast of the monodispersed W/O of small size of various form
Liquid；Rhutesh K.Shah etc. utilizes coaxial shear mode, is prepared for substance, dual, multiple emulsion.But common microfluid
Emulsion size prepared by technology is less, at micro/nano level, is mainly used in the fields such as biology, medicine, chemical industry, oil.
At present, a kind of generating means that can prepare the monodispersed dual breast grain of grade is needed badly.
Summary of the invention
The technical problems to be solved in the utility model is to provide a kind of three hole coaxial-types dual breast grain generating means.
Three hole coaxial-types of the present utility model dual breast grain generating means, is characterized in, including generator body and three-phase
Pipeline, three-phase pipeline inserts generator body and forms coaxial device.
Described generator body includes dististyle, upper cylinder, cylinder, lower cylinder, lower end-piece, folds the most successively
Add, be equipped with by the interference seal of boss and shrinkage pool between parts；After Pei Zhuan, between described upper dististyle and cylinder, there is mesophase
External solution pond is had between solution pool, cylinder and lower end-piece；Internal phase liquid outlet, cylindrical center are vertically opened in described upper dististyle center
Vertically open mesophase liquid outlet, phase liquid outlet over lower end-piece center is vertical；Internal phase liquid outlet, mesophase liquid outlet and foreign minister go out
Liquid mouth is coaxial, and internal diameter increases successively；Described upper cylinder sides level opens mesophase inlet, phase over lower cylinder sides level
Inlet.
Described three-phase pipeline includes internal phase pipeline, mesophase pipeline and foreign minister's pipeline；The external diameter of described internal phase pipeline
For D1；The internal diameter of described mesophase pipeline is d2, and external diameter is D2；The internal diameter of described foreign minister's pipeline is d3；D1 ＜ d2 ＜ D2
＜ d3；Time equipped, described internal phase pipeline inserts internal phase liquid outlet, and mesophase pipeline inserts mesophase liquid outlet, foreign minister's pipeline
Inserting foreign minister's liquid outlet, between liquid outlet and pipeline, interference seal is equipped with.
Described upper dististyle, upper cylinder, cylinder, lower cylinder, the material employing politef of lower end-piece, internal phase pipeline,
The material of mesophase pipeline and foreign minister's pipeline is glass.Polytetrafluoroethylmaterial material energy organic solvent-resistant corrodes, and has micro-elasticity, energy
Enough utilizing interference fit to realize sealing, glass is prone to carry out surface hydrophobe process, and organic solvent-resistant corrodes.
Described internal phase pipeline and foreign minister's pipeline are through TECH-0 reagent hydrophilic treated, and mesophase pipeline is through octadecyl front three
TMOS hydrophobic treatment.
Described internal phase pipeline and foreign minister's pipeline also can be through octadecyl trimethoxysilane hydrophobic treatment, mesophase pipeline
Process through the hydrophobic water of octadecyl trimethoxysilane.
Solution system flows through three hole coaxial-types of the present utility model dual breast grain generating means and produces dual breast grain, solution body
System includes internal phase solution, mesophase solution and external solution；Due to D1 ＜ d2 ＜ D2 ＜ d3, internal phase pipeline, mesophase pipeline and
Leaving gap in foreign minister's pipeline, internal phase solution enters internal phase pipeline, and mesophase solution flows into mesophase by mesophase inlet
Entering mesophase pipeline after solution pool, external solution enters foreign minister's pipeline after flowing into external solution pond by foreign minister's inlet.Logical
Cross change D1, d2, D2, d3 and can produce various sizes of dual breast grain.
Three hole coaxial-types dual breast grain can be realized by dististyle, upper cylinder, cylinder, lower cylinder, lower end-piece in dismounting, cleaning
Reusing of generating means.
The work process of three hole coaxial-types of the present utility model dual breast grain generating means is as follows:
A. set flow velocity, set the flow rates of internal phase solution as 2 ml/h ~ 5ml/h, the flow rates of mesophase solution
Being 2 ml/h ~ 5ml/h, the flow rates of external solution is 600 ml/h ~ 1500ml/h；
B. sample introduction, by external solution, mesophase solution, the order of internal phase solution, mixes successively outside foreign minister's pipeline inputs
Liquid, mesophase pipeline input mesophase solution, internal phase pipeline input internal phase solution；
C. collect, collect the dual breast grain produced in the exit of foreign minister's pipeline.
Three hole coaxial-types of the present utility model dual breast grain generating means can produce single dispersing major diameter dual breast grain, should
Device use coaxial shear mode, be successfully prepared internal diameter 800 μm ~ 1000 μm, the wall thickness 50 μm ~ 300 monodispersed water of μm/
PAMS-FB/PVA, water/PS-FB/PVA, water/DPS-FB/PVA W/O/W dual breast grain.By changing three-phase pipeline
Size, it is possible to prepare internal diameter 200 μm ~ 3000 μm dual breast grain；By changing the hydrophilicity and hydrophobicity of three-phase pipeline, moreover it is possible to
Enough prepare the double emulsion of Water-In-Oil bag oil (O1/W/O2).Three hole coaxial-types of the present utility model dual breast grain generating means behaviour
Making the most applied widely, easy cleaning, control accuracy is high, can effectively solve current emulsion micropackaging and send out and prepare grade polymer
Diameter, the uncontrollable problem of wall thickness in microsphere.
Accompanying drawing explanation
Fig. 1 is three hole coaxial-types of the present utility model dual breast grain generating means structure charts；
Fig. 2 is three hole coaxial-types of the present utility model dual breast grain generating means installation diagrams；
In figure, 1. go up 4. times cylinder 5. lower end-piece 6. internal phase liquid outlet 7. mesophases of cylinder 3. cylinder on dististyle 2.
Inlet 8. mesophase liquid outlet 9. foreign minister's inlet 10. foreign minister's liquid outlet 11. internal phase pipeline 12. mesophase pipeline
13. foreign minister's pipeline 14. mesophase solution pool 15. external solution ponds.
Detailed description of the invention
This utility model is described in detail below in conjunction with the accompanying drawings with embodiment.
Embodiment 1
As shown in Figure 1 and Figure 2, three hole coaxial-types of the present utility model dual breast grain generating means, including generator body and
Three-phase pipeline, three-phase pipeline inserts generator body and forms coaxial device.
Described generator body includes dististyle 1, upper cylinder 2, cylinder 3, lower cylinder 4, lower end-piece 5, depends on from top to bottom
Secondary superposition, is equipped with by the interference seal of boss and shrinkage pool between parts；After Pei Zhuan, have between described upper dististyle 1 and cylinder 3
External solution pond 15 is had between mesophase solution pool 14, cylinder 3 and lower end-piece 5；Described upper dististyle 1 center is vertically opened internal phase and is gone out
Liquid mouth 6, cylinder 3 center vertically opens mesophase liquid outlet 8, phase liquid outlet 10 over lower end-piece 5 center is vertical；Internal phase liquid outlet 6,
Mesophase liquid outlet 8 and foreign minister's liquid outlet 10 are coaxial, and internal diameter increases successively；Described upper cylinder 2 side horizontal is opened mesophase and is entered
Liquid mouth 7, phase inlet 9 over lower cylinder 4 side horizontal.
Described three-phase pipeline includes internal phase pipeline 11, mesophase pipeline 12 and foreign minister's pipeline 13；Described internal phase pipeline
The external diameter of 11 is D1；The internal diameter of described mesophase pipeline 12 is d2, and external diameter is D2；The internal diameter of described foreign minister's pipeline 13 is
d3；D1 ＜ d2 ＜ D2 ＜ d3；Time equipped, described internal phase pipeline 11 inserts internal phase liquid outlet 6, and mesophase pipeline 12 inserts centre
Phase liquid outlet 8, foreign minister's pipeline 13 inserts foreign minister's liquid outlet 10, and between liquid outlet and pipeline, interference seal is equipped with.
Solution system flows through three hole coaxial-types of the present utility model dual breast grain generating means and produces dual breast grain.
Internal phase pipeline 11 and foreign minister's pipeline 13 are through TECH-90 reagent hydrophilic treated, and mesophase pipeline 12 is through octadecyl three
Methoxy silane hydrophobic treatment, internal phase solution be distilled water, mesophase solution be the fluorobenzene solution of Poly-alpha-methylstyrene, outer
Phase solution is polyvinyl alcohol water solution.
The external diameter of internal phase pipeline 11 is 500 μm, and the internal diameter of mesophase pipeline 12 is 750 μm, and external diameter is 1000 μm, Wai Xiangguan
The inside diameter ranges in road 13 is 2200 μm.
Internal phase solution flow rate is 3 .5ml/h, 5 ml/h, 800 ml/h, produces internal diameter 880 μm, the water bag of wall thickness 170 μm
Water-In-Oil dual breast grain.
By changing mesophase outer diameter tube and foreign minister's internal diameter of the pipeline and three-phase flow parameters, it is possible to prepare various sizes of
W/O/W dual breast grain, design parameter is shown in Table embodiment 2-7 in 1.
Embodiment 8
Embodiment 8 with three hole coaxial-types of embodiment 1 dual breast grain generating means structure essentially identical, differ primarily in that
Internal phase pipeline 11 and foreign minister's pipeline 13 are through octadecyl trimethoxysilane hydrophobic treatment, and mesophase pipeline 12 is through octadecyl three
The hydrophobic water of methoxy silane processes, and internal phase solution is that silicone oil, mesophase solution are teos hydrolysis thing and external solution is
Silicone oil,
Internal phase solution flow rate is 2 .5ml/h, 3ml/h, 700 ml/h, produces internal diameter 820 μm, the Water-In-Oil of wall thickness 160 μm
Bag oil dual breast grain.
Table 1
This utility model is not limited to above-mentioned detailed description of the invention, and person of ordinary skill in the field visualizes from above-mentioned
Sending out, without performing creative labour, done all conversion, within all falling within protection domain of the present utility model.
Claims (1)
1. a hole coaxial-type dual breast grain generating means, it is characterised in that include generator body and three-phase pipeline, three-phase
Pipeline inserts generator body and forms coaxial device；
Described generator body includes dististyle (1), upper cylinder (2), cylinder (3), lower cylinder (4), lower end-piece (5), from upper
It is sequentially overlapped under to, is equipped with by the interference seal of boss and shrinkage pool between parts；After Pei Zhuan, described upper dististyle (1) and circle
Have between post (3) between mesophase solution pool (14), cylinder (3) and lower end-piece (5) and have external solution pond (15)；Described upper end
Internal phase liquid outlet (6) is vertically opened at sheet (1) center, and mesophase liquid outlet (8) is vertically opened at cylinder 3 center, and lower end-piece (5) center is vertical
Over phase liquid outlet (10)；Internal phase liquid outlet (6), mesophase liquid outlet (8) and foreign minister's liquid outlet (10) are coaxial, and internal diameter increases successively
Add；Described upper cylinder (2) side horizontal opens mesophase inlet (7), phase inlet (9) over lower cylinder (4) side horizontal；
Described three-phase pipeline includes internal phase pipeline (11), mesophase pipeline (12) and foreign minister's pipeline (13)；Described internal phase pipe
The external diameter in road (11) is D1；The internal diameter of described mesophase pipeline (12) is d2, and external diameter is D2；Described foreign minister's pipeline (13)
Internal diameter is d3；D1 ＜ d2 ＜ D2 ＜ d3；Time equipped, described internal phase pipeline (11) inserts internal phase liquid outlet (6), mesophase pipeline
(12) inserting mesophase liquid outlet (8), foreign minister's pipeline (13) inserts foreign minister's liquid outlet (10), and between liquid outlet and pipeline, interference is close
Envelope is equipped；
Described internal phase pipeline (11) and foreign minister's pipeline (13) are through TECH-90 reagent hydrophilic treated, and mesophase pipeline (12) is through ten
Eight alkyl trimethoxysilane hydrophobic treatment；
Described internal phase pipeline (11) and foreign minister's pipeline (13) are through octadecyl trimethoxysilane hydrophobic treatment, mesophase pipeline
(12) through octadecyl trimethoxysilane hydrophobic treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620691682.XU CN205761069U (en) | 2016-07-05 | 2016-07-05 | A kind of three hole coaxial-types dual breast grain generating means |
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| CN201620691682.XU CN205761069U (en) | 2016-07-05 | 2016-07-05 | A kind of three hole coaxial-types dual breast grain generating means |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106040115A (en) * | 2016-07-05 | 2016-10-26 | 中国工程物理研究院激光聚变研究中心 | Three-hole coaxial double-emulsion-particle generating device |
| CN114653414A (en) * | 2022-03-23 | 2022-06-24 | 广东省科学院生物与医学工程研究所 | Capillary microfluidic device with interference fit for auxiliary positioning and preparation method thereof |
| CN115414972A (en) * | 2022-08-08 | 2022-12-02 | 广东省科学院生物与医学工程研究所 | Portable coaxial focusing micro-droplet generation device and micro-droplet preparation method |
-
2016
- 2016-07-05 CN CN201620691682.XU patent/CN205761069U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106040115A (en) * | 2016-07-05 | 2016-10-26 | 中国工程物理研究院激光聚变研究中心 | Three-hole coaxial double-emulsion-particle generating device |
| CN106040115B (en) * | 2016-07-05 | 2018-10-09 | 中国工程物理研究院激光聚变研究中心 | A kind of dual milk particle generating means of three hole coaxial-types |
| CN114653414A (en) * | 2022-03-23 | 2022-06-24 | 广东省科学院生物与医学工程研究所 | Capillary microfluidic device with interference fit for auxiliary positioning and preparation method thereof |
| CN114653414B (en) * | 2022-03-23 | 2024-02-02 | 广东省科学院生物与医学工程研究所 | Interference fit assisted positioning capillary microfluidic device and preparation method thereof |
| CN115414972A (en) * | 2022-08-08 | 2022-12-02 | 广东省科学院生物与医学工程研究所 | Portable coaxial focusing micro-droplet generation device and micro-droplet preparation method |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20161207 Termination date: 20190705 |
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| CF01 | Termination of patent right due to non-payment of annual fee |