CN205740997U - Thermal cycler and specimen holder elevating mechanism thereof - Google Patents
Thermal cycler and specimen holder elevating mechanism thereof Download PDFInfo
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- CN205740997U CN205740997U CN201620558667.8U CN201620558667U CN205740997U CN 205740997 U CN205740997 U CN 205740997U CN 201620558667 U CN201620558667 U CN 201620558667U CN 205740997 U CN205740997 U CN 205740997U
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- specimen holder
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Abstract
This utility model relates to thermal cycler, disclose thermal cycler and specimen holder elevating mechanism thereof, it includes cabinet (9), cabinet is provided with specimen holder elevating mechanism in (9), specimen holder elevating mechanism includes base plate (1), it is characterized in that: on base plate (1), be fixed with connecting rod (11), connecting rod (11) is provided with the travel(l)ing rest (2) that can slide up and down along connecting rod (11), and travel(l)ing rest connects the specimen holder support (4) for installing specimen holder (3).This utility model uses liftable specimen holder (3) to realize pressure to sample cell top, then ensures the good contact bottom sample cell and between specimen holder (3), its have simple to operate, the advantages such as convenient are installed.
Description
Technical field
This utility model relates to a kind of thermal cycler, has particularly related to a kind of thermal cycle with specimen holder elevating mechanism
Instrument.
Background technology
Biochemical reaction typically requires reaction liquid composition to be carried out under conditions of precise control of temperature, such as polymerase
Chain reaction (english abbreviation PCR).Reaction liquid composition is contained in sample cell, sample cell generally by the plastics of heat conduction or other
Material is made, and seals, to prevent evaporation.Then sample cell is inserted on specimen holder in the sample well dug.Sample
Seat is generally made up by cutting or other forming technique of metal or other Heat Conduction Materials.By heating-cooling device, control
The temperature of specimen holder processed, and by heat transfer, it is achieved to the control of reaction liquid temperature in sample cell.
In order to make sample cell contact with specimen holder well, to ensure heat-transfer effect, generally one pressure is set at sample cell top
Power apparatus, presses to sample cell top, and pressing force had both ensured that sample cell was indeformable and ruptured, and ensures bottom sample cell again and sample
Product seated connection touches good.Operate sample cell for the convenience of the users, as inserted or taking out sample cell, it usually needs first shed or discharge
Pressing force, then pressure apparatus is removed, thus expose specimen holder.
Current thermal cycler is all specimen holder maintains static, is realized sample cell top by the lifting of pressure apparatus
Pressure, this kind of mode when equipped with fluoroscopic examination module and for detecting amplification for the thermal cycler of fluorescence, due to
Its optical system is above its specimen holder, thus causes the pressure apparatus for pressing sample cell top to install inconvenience, difficult
To ensure good pressure effect.
Utility model content
The unhandy problem that this utility model brings owing to its specimen holder maintains static for existing thermal cycle,
Provide a kind of thermal cycler with specimen holder elevating mechanism.
In order to solve above-mentioned technical problem, this utility model is addressed by following technical proposals:
Thermal cycler, including cabinet, is provided with specimen holder elevating mechanism in cabinet.It is fixed with specimen holder on specimen holder support,
It is placed with sample cell on specimen holder, in cabinet, is further fixed on the pressure plare for compressing sample cell.By specimen holder lifting is made
Contact with pressure plare, then make pressure plare can sample cell top be entered under the retroaction of elevating mechanism internal pressure spring
Row pressure such that it is able to ensure can be good with specimen holder bottom sample cell contact.
Specimen holder elevating mechanism includes base plate, including base plate, base plate is fixed with connecting rod, and connecting rod is provided with can be along even
The travel(l)ing rest that extension bar slides up and down, travel(l)ing rest connects and has the specimen holder support for installing specimen holder.Propped up by activity
Frame promotes specimen holder support, thus realizes the lifting of specimen holder, and connecting rod is many, is evenly distributed on base plate, thus can make
Obtain travel(l)ing rest can steadily lift, then ensure the steady lifting of specimen holder.
As preferably, also including the cam mounting seat being fixed on base plate, cam mounting seat is provided with and is resisted against movable
The cam of frame, cam is free to rotate and travel(l)ing rest can be promoted to rise；The side that base plate is relative with cam is fixed with vertically leads
Rail, travel(l)ing rest is provided with the slide block coordinated with upright guide rail.The lifting of specimen holder, cam and roller is realized by cam mechanism
Cooperation more steady when specimen holder can be made to lift, do not have and rock；Upright guide rail is arranged on the end face relative with cam
On, more steady with the lifting that can make specimen holder under the cooperation of upright guide rail at slide block, it is to avoid travel(l)ing rest when hoisting
Situation low after height before existing, it is ensured that specimen holder can horizontal lifting, effectively prevent from being subject to during the pressure of sample cell top in specimen holder
Power is uneven.
As preferably, travel(l)ing rest is provided with the roller with cam engagement, and cam top is provided with for pair roller spacing
Stopper slot.And the stopper slot that pair roller is spacing is set at cam top, limit it after specimen holder can be elevated to certain position
Position, to facilitate operator to the operation of sample cell in specimen holder.
As preferably, travel(l)ing rest is connected by guide pillar nail with specimen holder support, and guide pillar nails on and is arranged with compression spring, pressure
The two ends up and down of power spring bear against on specimen holder support and travel(l)ing rest.By compression spring and coordinating that guide pillar is followed closely,
Travel(l)ing rest can be made when rising to certain position to have certain cushioning effect, and in effectively preventing specimen holder, sample cell is crushed.
As preferably, also include being connected with cam and for rotating the handle of cam.Cam is rotated, to sample by handle
It is more convenient to operate that seat lifts.
As preferably, specimen holder elevating mechanism also includes top board, is provided with for specimen holder support up and down in the middle part of top board
Cavity, is provided with protective cradle between top board and base plate.Protective cradle can effectively protect whole specimen holder elevating mechanism, also may be used simultaneously
The structure making whole elevating mechanism is more stable, compact.
As preferably, cam mounting seat includes that cam installs header board and cam installs back plate, and cam is installed back plate and is fixed on
On base plate, cam is installed the two ends of header board and is separately fixed in top board and cam installation back plate.This cam mounting seat is not only use
In installing cam, the structure more enabling to whole elevating mechanism is more stable.
As preferably, specimen holder frame bottom is provided with radiator, and radiator is provided with semiconductor chilling plate, semiconductor refrigerating
Sheet is between specimen holder and radiator.Can be realized in specimen holder by the dual function of radiator Yu semiconductor chilling plate
Sample cell preferably radiating effect.
As preferably, specimen holder elevating mechanism both sides are provided with horizontal guide rail, are provided with the water coordinated with horizontal guide rail in cabinet
Flat guide groove, horizontal guide rail slides at horizontal guide groove and makes the level pull-out in cabinet of described specimen holder elevating mechanism, so that
Obtain whole specimen holder elevating mechanism to pull out with the form of drawer-like or push in cabinet, facilitate the user behaviour to sample cell
Make.
This utility model, owing to have employed above technical scheme, has a significant technique effect:
This utility model uses liftable specimen holder to realize the pressure to sample cell top, then ensures bottom sample cell
And the good contact between specimen holder, its have simple to operate, the advantages such as convenient are installed.
Accompanying drawing explanation
Fig. 1 is the structural representation of this utility model embodiment 2.
Fig. 2 is the structural representation of this utility model embodiment 1.
Fig. 3 is the partial structurtes schematic diagram of Fig. 2.
The toponym that in accompanying drawing, each number designation is referred to is as follows: 1 base plate, 2 travel(l)ing rests, 3 specimen holders,
4 specimen holder supports, 5 handles, 6 top boards, 7 protective cradles, 8 radiators, 9 cabinets, 10 horizontal guide rails, 11
Connecting rod, 12 cam mounting seats, 13 cams, 21 guide pillar nails, 22 rollers, 23 slide blocks, 61 cavitys, 62 vertical
Guide rail, 81 semiconductor chilling plates, 91 horizontal guide grooves, 120 cams install back plate, 121 cams install header boards, 130
Stopper slot, 210 compression springs.
Detailed description of the invention
With embodiment, this utility model is described in further detail below in conjunction with the accompanying drawings.
Embodiment 1
Specimen holder elevating mechanism, as in figure 2 it is shown, include base plate 1 and top board 6, is provided with in the middle part of top board 6 for specimen holder support 4
Up and down cavity 61, is provided with protective cradle 7 between top board 6 and base plate 1, protective cradle 7 is used for protecting whole specimen holder liter
Descending mechanism.
Being fixed with connecting rod 11 on base plate 1, connecting rod 11 is provided with the travel(l)ing rest 2 that can slide up and down along connecting rod 11,
Connecting rod 11 is provided with the sliding sleeve that can slide up and down along connecting rod 11, and travel(l)ing rest 2 is slided up and down along connecting rod 11 by sliding sleeve.
There is the specimen holder support 4 for installing specimen holder 3 by guide pillar nail 21 connection on travel(l)ing rest 2, guide pillar nail 21 is arranged with pressure
Power spring 210, the two ends up and down of compression spring 210 bear against on specimen holder support 4 and travel(l)ing rest 2.Guide pillar nail 21
Nail rod partially passes through the end of travel(l)ing rest 2 and nail rod part and is fixed on specimen holder support 4, and travel(l)ing rest 2 is overcoming pressure
Can slide up and down along guide pillar nail 21 on the premise of spring 210 elastic force.Upright guide rail 62 it is additionally provided with between top board 6 and base plate 1, movable
Support 2 is provided with the slide block 23 coordinated with upright guide rail 62.
Being provided with radiator 8 bottom specimen holder support 4, radiator 8 is provided with semiconductor chilling plate 81, semiconductor chilling plate 81
Between radiator 8 and specimen holder 3.Also including the cam mounting seat 12 being fixed on base plate 1, cam mounting seat 12 includes convex
Wheel installs header board 121 and cam installs back plate 120, and cam is installed back plate 120 and is fixed on base plate 1, and cam installs header board 121
Two ends are separately fixed at top board 6 and cam is installed in back plate 120.Cam mounting seat 12 is provided with cam 13 free to rotate,
Being connected by a rotary shaft on cam 13 has one handle 5, handle 5 stretch out protective cradle 7 and can rotate by band moving cam 13.Movable
Frame 2 is provided with the roller 22 coordinated with cam 13, and cam 13 top is provided with for the spacing stopper slot 130 of pair roller 22.
The present embodiment hoists when needed specimen holder 3 time, by rotary handle 5 double-linked cam 13 mechanism so that cam
13 rotate, thus by cam 13 promote travel(l)ing rest 2 along connecting rod 11 upward sliding, and at slide block 23 and upright guide rail
The level realizing travel(l)ing rest 2 under the cooperation of 62 hoists；Along with the rising of travel(l)ing rest 2, it is arranged on the sample on travel(l)ing rest 2
Seat support 4 rises, and then makes pressure plare in the sample cell top contact cabinet 9 being placed in specimen holder 3, causes guide pillar nail 21
On compression spring 210 compression, make to contact with specimen holder 3 bottom sample cell under the counteracting force of compression spring 210
Well.When the roller 22 on travel(l)ing rest 2 falls into the stopper slot 130 on cam 13, whole specimen holder 3 rises and puts in place and pacified
Complete is locked in this position.
Embodiment 2
Thermal cycler, as shown in Figure 1-Figure 3, including cabinet 9, is provided with specimen holder elevating mechanism, specimen holder support in cabinet 9
It is fixed with specimen holder 3 on 4, specimen holder 3 is placed with sample cell, in cabinet 9, be further fixed on the pressure plare for compressing sample cell.
Wherein specimen holder elevating mechanism includes base plate 1 and top board 6, is provided with for specimen holder support 4 up and down in the middle part of top board 6
Cavity 61, be provided with protective cradle 7 between top board 6 and base plate 1, protective cradle 7 is used for protecting whole specimen holder elevating mechanism.
Being fixed with connecting rod 11 on base plate 1, connecting rod 11 is provided with the travel(l)ing rest 2 that can slide up and down along connecting rod 11,
Connecting rod 11 is provided with the sliding sleeve that can slide up and down along connecting rod 11, and travel(l)ing rest 2 is slided up and down along connecting rod 11 by sliding sleeve.
There is the specimen holder support 4 for installing specimen holder 3 by guide pillar nail 21 connection on travel(l)ing rest 2, guide pillar nail 21 is arranged with pressure
Power spring 210, the two ends up and down of compression spring 210 bear against on specimen holder support 4 and travel(l)ing rest 2.Guide pillar nail 21
Nail rod partially passes through the end of travel(l)ing rest 2 and nail rod part and is fixed on specimen holder support 4, and travel(l)ing rest 2 is overcoming pressure
Can slide up and down along guide pillar nail 21 on the premise of spring 210 elastic force.Upright guide rail 62 it is additionally provided with between top board 6 and base plate 1, movable
Support 2 is provided with the slide block 23 coordinated with upright guide rail 62.
Be provided with radiator 8 bottom specimen holder support 4, semiconductor chilling plate 81 between radiator 8 and specimen holder 3, from
And can realize sample cell preferably radiating effect in specimen holder 3.
Also including the cam mounting seat 12 being fixed on base plate 1, cam mounting seat 12 includes that cam installs header board 121 and convex
Wheel installs back plate 120, and cam is installed back plate 120 and is fixed on base plate 1, and cam is installed the two ends of header board 121 and is separately fixed at top
Plate 6 and cam are installed in back plate 120.Cam mounting seat 12 is provided with cam 13 free to rotate, by one turn on cam 13
Moving axis connects has one handle 5, handle 5 stretch out protective cradle 7 and can rotate by band moving cam 13.Travel(l)ing rest 2 is provided with and cam
13 rollers 22 coordinated, cam 13 top is provided with for the spacing stopper slot 130 of pair roller 22.
In the present embodiment, top board 6 both sides at specimen holder elevating mechanism are provided with horizontal guide rail 10, are provided with and level in cabinet 9
The horizontal guide groove 91 that guide rail 10 coordinates, horizontal guide rail 10 slides at horizontal guide groove 91 and makes described specimen holder elevating mechanism from machine
Level pull-out in case 9.The turnover structure using this kind of drawer-like realizes exposure and the closing of specimen holder 3, then convenient use
Person is to the operation of sample cell in specimen holder 3.When sample cell top is pressed so that connecing with specimen holder 3 bottom sample cell by needs
When touching good, whole specimen holder elevating mechanism is pushed completely in cabinet 9 so that when specimen holder 3 is under closed state, then
Rotary handle 5 double-linked cam 13 mechanism so that cam 13 rotates, thus promote travel(l)ing rest 2 along connecting rod by cam 13
11 upward slidings, and hoist with the level realizing travel(l)ing rest 2 under the cooperation of upright guide rail 62 at slide block 23；Along with activity is propped up
The rising of frame 2, the specimen holder support 4 being arranged on travel(l)ing rest 2 rises, and then makes the sample cell being placed in specimen holder 3
Pressure plare in top contact cabinet 9, causes compression spring 210 compression on guide pillar nail 21, at the anti-work of compression spring 210
Make under Yong Li to contact well with specimen holder 3 bottom sample cell.When the roller 22 on travel(l)ing rest 2 fall on cam 13 spacing
During groove 130, whole specimen holder 3 rises and puts in place and be locked in this position by safety.
In a word, the foregoing is only preferred embodiment of the present utility model, all according to this utility model claim institute
Impartial change and the modification made, all should belong to the covering scope of this utility model patent.
Claims (10)
1. specimen holder elevating mechanism, including base plate (1), it is characterised in that: it is fixed with connecting rod (11), connecting rod on base plate (1)
(11) being provided with the travel(l)ing rest (2) that can slide up and down along connecting rod (11), travel(l)ing rest connects to be had for installing specimen holder
(3) specimen holder support (4).
Specimen holder elevating mechanism the most according to claim 1, it is characterised in that: also include being fixed on base plate (1) is convex
Wheel mounting seat (12), cam mounting seat (12) is provided with the cam (13) being resisted against travel(l)ing rest (2), and cam (13) can freely turn
Move and travel(l)ing rest (2) can be promoted to rise；The side that base plate (1) is relative with cam (13) is fixed with upright guide rail (62), movable
Support (2) is provided with the slide block (23) coordinated with upright guide rail (62).
Specimen holder elevating mechanism the most according to claim 2, it is characterised in that: travel(l)ing rest (2) is provided with and cam
(13) roller (22) coordinated, cam (13) top is provided with for the spacing stopper slot (130) of pair roller (22).
Specimen holder elevating mechanism the most according to claim 1, it is characterised in that: travel(l)ing rest (2) and specimen holder support (4)
Being connected by guide pillar nail (21), guide pillar nail (21) is arranged with compression spring (210), the two ends up and down of compression spring (210) are divided
It is not resisted against on specimen holder support (4) and travel(l)ing rest (2).
Specimen holder elevating mechanism the most according to claim 2, it is characterised in that: also include being connected with cam (13) and being used for
Rotate the handle (5) of cam (13).
Specimen holder elevating mechanism the most according to claim 2, it is characterised in that: also include top board (6), top board (6) middle part
It is provided with the cavity (61) up and down for specimen holder support (4), between top board (6) and base plate (1), is provided with protective cradle (7).
Specimen holder elevating mechanism the most according to claim 6, it is characterised in that: cam mounting seat (12) includes that cam is installed
Header board (121) and cam install back plate (120), and cam is installed back plate (120) and is fixed on base plate (1), and cam installs header board
(121) two ends are separately fixed at top board (6) and cam is installed in back plate (120).
Specimen holder elevating mechanism the most according to claim 1, it is characterised in that: specimen holder support (4) bottom is provided with heat radiation
Device (8), radiator (8) is provided with semiconductor chilling plate (81).
9. thermal cycler, including cabinet (9), it is characterised in that cabinet is provided with described in claim 1-8 any one in (9)
Specimen holder elevating mechanism, specimen holder support (4) is fixed with specimen holder (3), and cabinet is further fixed on for compressing sample cell in (9)
Pressure plare.
Thermal cycler the most according to claim 9, it is characterised in that: described specimen holder elevating mechanism both sides are provided with water
Level gauge (10), is provided with the horizontal guide groove (91) coordinated with horizontal guide rail (10) in cabinet (9), horizontal guide rail (10) is led in level
Groove (91) slides and makes the level pull-out in cabinet (9) of described specimen holder elevating mechanism.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620558667.8U CN205740997U (en) | 2016-06-12 | 2016-06-12 | Thermal cycler and specimen holder elevating mechanism thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620558667.8U CN205740997U (en) | 2016-06-12 | 2016-06-12 | Thermal cycler and specimen holder elevating mechanism thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205740997U true CN205740997U (en) | 2016-11-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620558667.8U Active CN205740997U (en) | 2016-06-12 | 2016-06-12 | Thermal cycler and specimen holder elevating mechanism thereof |
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| CN (1) | CN205740997U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108587897A (en) * | 2018-05-03 | 2018-09-28 | 莫纳（苏州）生物科技有限公司 | A kind of PCR amplification device |
| CN112442437A (en) * | 2020-05-30 | 2021-03-05 | 杭州天微基因科技有限公司 | Novel elastic hot cover mechanism for nucleic acid amplification detection |
| CN113025467A (en) * | 2021-04-15 | 2021-06-25 | 杭州安誉科技有限公司 | Deoxyribonucleic acid extraction element among nucleic acid testing process |
-
2016
- 2016-06-12 CN CN201620558667.8U patent/CN205740997U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108587897A (en) * | 2018-05-03 | 2018-09-28 | 莫纳（苏州）生物科技有限公司 | A kind of PCR amplification device |
| CN108587897B (en) * | 2018-05-03 | 2021-08-10 | 莫纳（苏州）生物科技有限公司 | PCR amplification device |
| CN112442437A (en) * | 2020-05-30 | 2021-03-05 | 杭州天微基因科技有限公司 | Novel elastic hot cover mechanism for nucleic acid amplification detection |
| CN113025467A (en) * | 2021-04-15 | 2021-06-25 | 杭州安誉科技有限公司 | Deoxyribonucleic acid extraction element among nucleic acid testing process |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |