CN205665079U - In vitro carries out non -contact ultrasonic wave focusing arrangement for sample preparation - Google Patents

In vitro carries out non -contact ultrasonic wave focusing arrangement for sample preparation Download PDF

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Publication number
CN205665079U
CN205665079U CN201620538983.9U CN201620538983U CN205665079U CN 205665079 U CN205665079 U CN 205665079U CN 201620538983 U CN201620538983 U CN 201620538983U CN 205665079 U CN205665079 U CN 205665079U
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China
Prior art keywords
test tube
piezoelectricity
focusing arrangement
spherical crown
housing
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CN201620538983.9U
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Chinese (zh)
Inventor
朱阿春
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HIANERTEC (SUZHOU) CO Ltd
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HIANERTEC (SUZHOU) CO Ltd
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Abstract

The utility model provides an in vitro carries out non -contact ultrasonic wave focusing arrangement for sample preparation includes at least: casing, ultrasonic focusing structure, the ultrasonic focusing structure is accomodate in the casing, wear to be equipped with the terminal in the ultrasonic focusing structure, terminal connection has the cable, the ultrasonic focusing structure has the depressed area, just the acoustic medium is led to the splendid attire in the depressed area. Place this in vitro carries out non -contact ultrasonic wave focusing arrangement for sample preparation in the basin to and make that the sample is located in the test tube focus department of ultrasonic focusing structure, the ultrasonic focusing structure can be with supersound mechanical oscillation energy focusing to a small region, and the energy density in this small region can handle and to carry out the sample handled in high strength or high energy density occasion, and sample preparation is efficient, in addition, this in vitro carries out non -contact ultrasonic wave focusing arrangement for sample preparation is applicable to the test tube that various materials were made.

Description

Sample process non-contact type ultrasonic focusing arrangement is carried out in test tube
Technical field
This utility model relates to a kind of device in vitro carrying out sample process, particularly relates in a kind of test tube Carry out sample process non-contact type ultrasonic focusing arrangement.
Background technology
Ultrasound wave is the mechanical wave of a kind of dither exceeding pleasant range of audibility, when its vibration is delivered in liquid, In addition to producing positive/negative-pressure vibration wave alternately in a liquid, also can produce cavitation effect (the impact shock wave of high-frequency and high-voltage), these are two years old Plant vibrating function and some objects such as cell aggregates in liquid will be produced destruction, breaking cellular wall and pulverization;By controlling The size of vibrational energy, it is possible to use above-mentioned vibrating function is to carry out contactless process to sample in test tube, as entered sample The dispersion of row cell separation, solution, liquid blending, stirring etc. process.
At present, the mode in vitro carrying out sample process mainly has centrifugal separation, ultrasound bath method, Low-Frequency Mechanical Vibratory drilling method (such as waving method), magnetic force stir shaking manipulation, and ultrasound wave contact method, and wherein, ultrasound bath method and ultrasound wave are straight Connect contact method and meet the tendency the most extensive.Ultrasound bath method is to be placed in water by test tube, and ultrasound wave vibrates the shock wave of generation in water and passes It is delivered in test tube outer wall, more incoming test tube in liquid;Ultrasound wave contact method is that vibration head directly contacts test tube outer wall, but This method may be only available for plastic test tube, and the time can not be oversize.Ultrasound bath method and ultrasound wave contact method need processing There is certain limitation at the sample that high intensity or high-energy-density occasion carry out processing, especially some to be required high High intensity or the sample of high-energy-density occasion, such as human hair, the solid sample such as calculus is just difficult to be competent at.
Utility model content
The shortcoming of prior art in view of the above, the purpose of this utility model carries out sample in being to provide a kind of test tube Process and use non-contact type ultrasonic focusing arrangement, be used for solving above-mentioned technical problem present in prior art.
For achieving the above object and other relevant purposes, this utility model provides following technical scheme:
Carry out sample process non-contact type ultrasonic focusing arrangement in a kind of test tube, at least include: housing, focus ultrasonic Structure, described focus ultrasonic structure is accommodated in described housing, is equipped with binding post, described wiring in described focus ultrasonic structure Post connects has cable, described cable to be located in the wall of described housing;Described focus ultrasonic structure has depressed area, and described recessed It is loaded with acoustic conductive media in falling into district.
Further, described focus ultrasonic structure is piezoelectricity spherical crown;Described housing has an opening, and described opening faces Described piezoelectricity spherical crown concave surface, and the described opening described piezoelectricity spherical crown concave surface of covering.
Further, the opening part of described housing is provided with leads sound film, described in lead sound film and surround with described piezoelectricity spherical crown concave surface One closed containing cavity;Described acoustic conductive media is positioned at described closed containing cavity;It is provided with on described housing for cooling down described piezoelectricity spherical crown Cooling system.
Further, described cooling system includes feed pipe and drain pipe;Described feed pipe and drain pipe are worn respectively It is located on described housing wall.
Further, described acoustic conductive media is water;Described feed pipe and drain pipe one end respectively with described airtight appearance Chamber is connected.
Further, described piezoelectricity spherical crown outer wall top seals with described inner walls and is connected, and outside described piezoelectricity spherical crown Wall and described inner walls form an airtight cooling chamber;Described feed pipe and drain pipe one end respectively with described airtight cooling Chamber is connected.
Further, described housing is additionally provided with installing hole, and described installing hole faces described piezoelectricity spherical crown convex surface, described peace Dress is provided with seal cover board on hole.
Further, described housing wall being provided with water joint, described cable is connected with described water joint.
As it has been described above, carry out sample process non-contact type ultrasonic focusing arrangement in test tube of the present utility model, have Following beneficial effect:
Place carrying out sample process non-contact type ultrasonic focusing arrangement in this test tube in the sink, and make examination In pipe, sample is positioned at the focusing of described focus ultrasonic structure depressed area;When transducer works, described focus ultrasonic structure energy Enough by ultrasonic mechanical vibration Voice segment to tiny area, adding the energy density of tiny area to a great extent, this is micro- The energy density of zonule can process the sample that needs carry out processing, and sample process in high intensity or high-energy-density occasion Efficiency is high;It addition, carry out sample process non-contact type ultrasonic focusing arrangement in this test tube to be applicable to what various material was made Test tube, is beneficial to promote the use of.
Accompanying drawing explanation
Fig. 1 carries out the signal of sample process non-contact type ultrasonic focusing arrangement in being shown as test tube of the present utility model Figure.
Fig. 2 carries out sample process non-contact type ultrasonic focusing arrangement and uses shape in being shown as test tube of the present utility model State schematic diagram.
Element numbers explanation
1 housing
2 piezoelectricity spherical crowns
3 binding posts
4 cables
5 water joints
6 seal cover boards
7 tanks
8 test tubes
Detailed description of the invention
By particular specific embodiment, embodiment of the present utility model being described below, those skilled in the art can be by this Content disclosed by description understands other advantages of the present utility model and effect easily.
It should be clear that structure depicted in this specification institute accompanying drawings, ratio, size etc., the most only in order to coordinate description to be taken off The content shown, understands for those skilled in the art and reads, being not limited to this utility model enforceable restriction bar Part, therefore do not have technical essential meaning, the modification of any structure, the change of proportionate relationship or the adjustment of size, do not affecting Under effect that this utility model can be generated by and the purpose that can reach, all should still fall in the technology disclosed in this utility model In the range of Rong Suoneng is contained.Meanwhile, in this specification cited as " on ", D score, "left", "right", " middle " and " one " Deng term, be merely convenient to narration understand, and be not used to limit the enforceable scope of this utility model, its relativeness It is altered or modified, is changing under technology contents without essence, when being also considered as the enforceable category of this utility model.
As it is shown in figure 1, this utility model carries out sample process non-contact type ultrasonic in providing a kind of test tube focuses on dress Putting, at least include: housing 1, focus ultrasonic structure, described focus ultrasonic structure is accommodated in described housing 1, described focus ultrasonic Being equipped with binding post 3 in structure, described binding post 3 connects has cable 4, described cable 4 to be located in the wall of described housing 1;Institute State in focus ultrasonic structure has depressed area, and described depressed area and be loaded with acoustic conductive media.Preferably, the length of described binding post 3 Degree direction centrage is by described focus ultrasonic structure centre;Described binding post 3 connects has cable 4, described cable 4 to be located in institute State in the wall of housing 1.Preferably, described housing 1 wall is provided with water joint 5, described cable 4 and described water joint 5 phase Even.
With reference to Fig. 2 when being placed on carrying out sample process non-contact type ultrasonic focusing arrangement in this test tube in tank 7, And test tube 8 is positioned at the focusing of described focus ultrasonic structure depressed area;During transducer work, described focus ultrasonic structure energy Enough by ultrasonic mechanical vibration Voice segment to tiny area, adding the energy density of tiny area to a great extent, this is micro- The energy density of zonule can process the sample that needs carry out processing, and sample process in high intensity or high-energy-density occasion Efficiency is high.
With reference to Fig. 1 and Fig. 2, described focus ultrasonic structure is piezoelectricity spherical crown 2;Described housing 1 has an opening, described opening Face described piezoelectricity spherical crown 2 concave surface, and described opening covers described piezoelectricity spherical crown 2 concave surface.Sample is carried out in by this test tube When process non-contact type ultrasonic focusing arrangement is placed in tank 7, the water in described tank 7 can flow into described piezoelectricity spherical crown In 2, and serve as conducting medium.
As further improvement of the utility model, the opening part at described housing 1 is provided with leads sound film, described in lead sound film with Described piezoelectricity spherical crown 2 concave surface surrounds a closed containing cavity;Described acoustic conductive media is positioned at described closed containing cavity;Pacify on described housing 1 Equipped with the cooling system for cooling down described piezoelectricity spherical crown 2.
Described cooling system includes feed pipe and drain pipe;Described feed pipe and drain pipe are located in described shell respectively On body 1 wall.
When the described acoustic conductive media in described closed containing cavity is water;Described feed pipe and drain pipe one end respectively with Described closed containing cavity is connected.During work, described piezoelectricity spherical crown 2 and water generation heat exchange in described closed containing cavity;Described feed pipe Constantly inputting water in described closed containing cavity, the most described drain pipe does not stop to discharge water in described closed containing cavity such that it is able to In ensureing described closed containing cavity, coolant-temperature gage is the highest, and then avoids described piezoelectricity spherical crown 2 and damage because of water temperature over-high, extends and makes Use the life-span.
Described acoustic conductive media in described closed containing cavity can also be silica gel;Described piezoelectricity spherical crown 2 outer wall top is with described Housing 1 inner wall sealing is connected, and described piezoelectricity spherical crown 2 outer wall forms an airtight cooling chamber with described housing 1 inwall;Described confession Water pipe is connected with described airtight cooling chamber respectively with drain pipe one end.During work, described piezoelectricity spherical crown 2 and described airtight cooling Intracavity water generation heat exchange, described feed pipe constantly inputs water in described closed containing cavity, and the most described drain pipe does not stop institute In stating closed containing cavity, water is discharged such that it is able in ensureing described closed containing cavity, coolant-temperature gage is the highest, and then avoids described piezoelectricity ball Hat 2 damages because of water temperature over-high, extends service life.
With reference to Fig. 1, installing and safeguard described piezoelectricity spherical crown 2 and binding post 3 for convenience, described housing 1 is additionally provided with peace Dress hole, described installing hole faces described piezoelectricity spherical crown 2 convex surface, described installing hole is provided with seal cover board 6.Preferably, institute Stating installing hole and be located at described housing 1 bottom surface, and described installing hole is not less than the round bottom of described piezoelectricity spherical crown 2, described opening is offered At described housing 1 end face, see Fig. 1.Described piezoelectricity spherical crown 2 end face and outer wall upper end all coordinate with described housing 1 inwall so that institute State piezoelectricity spherical crown 2 outer wall and form a closed cavity with described housing 1 inwall, seal cover board 6.Preferably, outside described piezoelectricity spherical crown 2 Wall is circumferentially machined with the circumferential wall matched with described housing 1 inwall.
Preferably, with reference to Fig. 1, described housing 1 is in tubular.Described installing hole it is provided with at the bottom of the cylinder of described tubular shell 1, described The cylinder of tubular shell 1 backs down and is provided with described opening, and described opening is rounded, and its diameter is less than described tubular shell 1 diameter.
In sum, carry out sample process non-contact type ultrasonic focusing arrangement in test tube of the present utility model to be placed In tank 7, and in test tube 8, sample is positioned at the focusing of described focus ultrasonic structure;When transducer works, described ultrasonic Focusing structure can add the energy of tiny area to a great extent by ultrasonic mechanical vibration Voice segment to tiny area Density, the energy density of this tiny area can process the sample that needs carry out processing in high intensity or high-energy-density occasion, And sample process efficiency is high;It is applicable to various it addition, carry out sample process non-contact type ultrasonic focusing arrangement in this test tube The test tube 8 that material is made, is beneficial to promote the use of.Further, since test tube 8 need not directly contact with transducer, test tube 8 is the most only It is confined to plastic cement test tube 8, it is possible to use teat glass 8, it is seen that the requirement to test tube 8 is greatly reduced.Therefore, this test tube Inside carry out sample process non-contact type ultrasonic focusing arrangement and be applicable to the test tube 8 that various material is made, be beneficial to promote the use of. So, this utility model effectively overcomes various shortcoming of the prior art and has high industrial utilization.
Above-described embodiment only illustrative principle of the present utility model and effect thereof are new not for limiting this practicality Type.Above-described embodiment all can be carried out by any person skilled in the art under spirit and the scope of the present utility model Modify or change.Therefore, all art have usually intellectual without departing from the spirit disclosed in this utility model Modify with all equivalences completed under technological thought or change, must be contained by claim of the present utility model.

Claims (8)

1. carry out sample process non-contact type ultrasonic focusing arrangement in a test tube, it is characterised in that at least include: housing (1), focus ultrasonic structure, in described focus ultrasonic structure is accommodated in described housing (1), described focus ultrasonic structure is equipped with Binding post (3), described binding post (3) connects has cable (4), described cable (4) to be located in the wall of described housing (1);Described Focus ultrasonic structure is loaded with acoustic conductive media in having depressed area, and described depressed area.
Carrying out sample process non-contact type ultrasonic focusing arrangement in test tube the most according to claim 1, its feature exists In: described focus ultrasonic structure is piezoelectricity spherical crown (2);Described housing (1) has an opening, and described opening faces described piezoelectricity Spherical crown (2) concave surface, and described opening described piezoelectricity spherical crown (2) concave surface of covering.
Carrying out sample process non-contact type ultrasonic focusing arrangement in test tube the most according to claim 2, its feature exists In: the opening part of described housing (1) is provided with leads sound film, described in lead sound film and described piezoelectricity spherical crown (2) concave surface and surround an airtight appearance Chamber;Described acoustic conductive media is positioned at described closed containing cavity;It is provided with on described housing (1) for cooling down described piezoelectricity spherical crown (2) Cooling system.
Carrying out sample process non-contact type ultrasonic focusing arrangement in test tube the most according to claim 3, its feature exists In: described cooling system includes feed pipe and drain pipe;Described feed pipe and drain pipe are located in described housing (1) respectively On wall.
Carrying out sample process non-contact type ultrasonic focusing arrangement in test tube the most according to claim 4, its feature exists In: described acoustic conductive media is water;Described feed pipe is connected with described closed containing cavity respectively with drain pipe one end.
Carrying out sample process non-contact type ultrasonic focusing arrangement in test tube the most according to claim 4, its feature exists In: described piezoelectricity spherical crown (2) outer wall top is connected with described housing (1) inner wall sealing, and described piezoelectricity spherical crown (2) outer wall and institute State housing (1) inwall and form an airtight cooling chamber;Described feed pipe and drain pipe one end respectively with described airtight cooling chamber It is connected.
7. according to carrying out sample process non-contact type ultrasonic focusing arrangement in the test tube described in any one of claim 2 to 6, It is characterized in that: described housing (1) is additionally provided with installing hole, described installing hole faces described piezoelectricity spherical crown (2) convex surface, described peace Dress is provided with seal cover board (6) on hole.
Carrying out sample process non-contact type ultrasonic focusing arrangement in test tube the most according to claim 1, its feature exists In: being provided with water joint (5) on described housing (1) wall, described cable (4) is connected with described water joint (5).
CN201620538983.9U 2016-06-03 2016-06-03 In vitro carries out non -contact ultrasonic wave focusing arrangement for sample preparation Active CN205665079U (en)

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CN201620538983.9U CN205665079U (en) 2016-06-03 2016-06-03 In vitro carries out non -contact ultrasonic wave focusing arrangement for sample preparation

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CN201620538983.9U CN205665079U (en) 2016-06-03 2016-06-03 In vitro carries out non -contact ultrasonic wave focusing arrangement for sample preparation

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115069319A (en) * 2022-06-29 2022-09-20 深圳达远辰光科技有限公司 Method and system for preparing liquid drops by focused ultrasound, detection equipment and storage medium

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115069319A (en) * 2022-06-29 2022-09-20 深圳达远辰光科技有限公司 Method and system for preparing liquid drops by focused ultrasound, detection equipment and storage medium

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