CN205612584U - Rat jugular vein hole blood sampling fixing device - Google Patents
Rat jugular vein hole blood sampling fixing device Download PDFInfo
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- CN205612584U CN205612584U CN201620182861.0U CN201620182861U CN205612584U CN 205612584 U CN205612584 U CN 205612584U CN 201620182861 U CN201620182861 U CN 201620182861U CN 205612584 U CN205612584 U CN 205612584U
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- fixing device
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- baoding
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Abstract
The utility model belongs to the technical field of device for the animal experiment, concretely relates to rat jugular vein hole blood sampling fixing device, solid fixed ring festival of animal when can be used to to use big mice to adopt the blood sampling of jugular vein hole way in as experimental animals's pharmacology or the research of drug metabolism dynamics. It includes components such as base, baoding support, static line, fixed crab -bolt and headgear, the base is the rubber material, and baoding support is stainless steel, wooden or organic glass material, and fixed crab -bolt links to each other with baoding support, and the headgear is hollow tube -shape, and the one end opening seals for one section, and the blind end is equipped with the ventilation breather, and the fixed page or leaf that is close to the open end has the reference mark, and accessible activity page or leaf freedom adjustment open -ended diameter keeps the comfort level again so that the rat head can safely be fixed. The utility model discloses a fixing device structure is reasonable, easy operation, convenient to use, and high -efficient fixed when can be used to the blood sampling of rat jugular vein hole is applicable to research institutions, medical institution and pharmacy enterprise laboratory etc..
Description
Technical field
The utility model belongs to the technical field of zoopery device, it is specifically related to a kind of rat jugular sinus fixing device for sampling blood, can be used for the pharmacology with big white mouse as animal used as test or pharmacokinetics research using the animal during blood sampling of jugular sinus approach fix link.
Background technology
Rat is animal used as test conventional in pharmacological experiment and pharmacokinetic, and blood collection is to ensure the important step that pharmacology mark detects in time or serum/plasma drug content accurately measures.Traditional retroorbital venous clump blood-sampling method has and (easily causes to Damage of Rats is big and infect and blind;Peripheral blood routine blood indexes compensatory changes) or blood sampling volume uncontrollable (when particularly taking a blood sample, blood spills, and anthemorrhagic difficulty and cause blood to waste in a large number) etc. limit, impact is produced on the physiology of animal used as test, psychology, and and then affects quality of experiments.Rat jugular sinus blood volume enriches, and has the protection of abundant skin and mucous membrane thereof, can realize that accurately controlling blood sampling volume farthest reduces the damage to animal as blood sampling puts in place simultaneously, thus ensure quality of experiments.Adopting that take a blood sample in this way it is crucial that the fixing link of animal, suitable fixing device is favorably improved the comfort level when blood sampling for the animal and compliance, and makes blood sampling site fully expose.Have not yet to see commercialization or there is the rat jugular sinus fixing device for sampling blood of independent intellectual property right.
Content of the invention
The purpose of this utility model is the problem for above-mentioned existence, and provides a kind of rat jugular sinus fixing device for sampling blood, uses and includes base, and described base is provided with Baoding support;Described Baoding support includes one, and for placing the triangular prism of rat body and one, for placing cuboid two parts of rat head, the right-angle surface of described cuboid and triangular prism adjoins, and the cross section of this Baoding support is overall at right angles trapezoidal;Leading flank and trailing flank at cuboid are respectively provided with fixing crab-bolt, and this fixing crab-bolt is near triangular prism;Also including 2 fixing lines, this fixing line is for being fixed the foreleg of rat respectively;Also including headgear, described headgear is the tubular of hollow, and one end is openend, and one end is blind end, and described blind end is provided with spiracle, and bore dia is 0.3-0.5
cm ;Headgear external diameter is 5-6 cm, and headgear wall thickness is 1-2 mm;Openend is divided into fixed page and active page by crack, is provided with I, II two gears in fixed page, is carried out the adjustment of opening diameter by Compressive activities page.Can accomplish the technical scheme of the abundant exposure of the comfort level behind rat Baoding and blood sampling site, principle is simple, easy to use, can be with Reusability.
The technical solution of the utility model is:
A kind of rat jugular sinus fixing device for sampling blood, including base, it is characterised in that described base is provided with Baoding support;Described Baoding support includes one, and for placing the triangular prism of rat body and one, for placing cuboid two parts of rat head, the right-angle surface of described cuboid and triangular prism adjoins, and the cross section of this Baoding support is overall at right angles trapezoidal;Leading flank and trailing flank at cuboid are respectively provided with fixing crab-bolt, and this fixing crab-bolt is near triangular prism;Also including 2 fixing lines, this fixing line is for being fixed the foreleg of rat respectively;Also including headgear, described headgear is the tubular of hollow, and one end is openend, and one end is blind end, and described blind end is provided with spiracle, and bore dia is 0.3-0.5
cm ;Headgear external diameter is 5-6 cm, and headgear wall thickness is 1-2 mm;Openend is divided into fixed page and active page by crack, is provided with I, II two gears in fixed page, is carried out the adjustment of opening diameter by Compressive activities page.The abundant exposure of the comfort level behind rat Baoding and blood sampling site can be accomplished.
Feature of the present utility model also has:
Described base is quality of rubber materials, in order to buffer in experimentation with impulsive force when contacting between experimental bench, Protection platform and Baoding support.
Described Baoding bracket clamp is connected on base, can be convenient for changing.
Described Baoding support is adhesively fixed with base and is connected, and can be convenient for changing.
Described Baoding support is stainless steel, wooden or lucite material, supporting bable tops when fixing as rat.
Animal captures the handedness of people for convenience, and leading flank and trailing flank at cuboid are respectively provided with fixing crab-bolt, generally 3-5, and the mode can welded fixing crab-bolt or screw is fixed on cuboid side, and elasticity with fixing line can be adjusted flexibly.
Described fixing line is the ball of string that cotton thread or nylon wire etc. are soft, comfortable, be easy to knotting and untwisting, is typically formed by two in a sleeve fixture mechanism, and all rolling in use for each is that two-wire uses, a diameter of 1.5-2.5 mm.
Described fixing line, wherein one end of a fixing line is fixed in fixing crab-bolt, and the other end dissociates, for beating a forelimb wrist of unijunction Baoding rat;Another fixing line two ends are all free, and one end is for beating unijunction Baoding rat another forelimb wrist, and the other end is drawn by Baoding personnel when blood sampling, and rat posture and position can be adjusted flexibly.
Described headgear adjusts rat head position and orientation for Nurses and protects Nurses not bitten use by rat simultaneously.Headgear is the tubular of hollow, uses PVC material, and described blind end spiracle is provided with 2-5, preferably 3;Openend is divided into fixed page and active page by crack, be provided with I(in fixed page and be suitable for female or below 250g), II (be suitable for male or more than 250g) two with reference to gears, the adjustment of opening diameter can be carried out by Compressive activities page, so that rat head can safe be fixed, keep again comfort level.
The beneficial effects of the utility model are: the utility model laboratory practices of combining closely designs, for rat jugular sinus blood collection procedure, can reach standardization, high efficiency, the target that quality of blood drawn is high, blood loss is few and animals comfortable degree high conventional blood collection mode or other jugular sinus fixing device for sampling bloods are not easily accomplished.Principle of device is simple, easy to use, can clean simple, it is adaptable to scientific research institutions, medical institutions and pharmacy corporation laboratory etc. with Reusability.
Brief description
Fig. 1 is rat jugular sinus fixing device for sampling blood structural representation of the present utility model;
Fig. 2 is the structural representation of headgear blind end.
Wherein, 1-base, 2-Baoding support, 3-fixes crab-bolt, and 4-fixes line, 5-headgear, 6-blind end, 7-openend, 8-active page, 9-gear I, 10-gear II, 11-crack, 12-fixed page, 13-spiracle, 21-triangular prism, 22-cuboid.
Detailed description of the invention
Below by specific embodiment, the technical solution of the utility model is described in detail.
Be can be seen that by Fig. 1 and Fig. 2; a kind of rat jugular sinus fixing device for sampling blood of the present utility model; including base 1; described base 1 is provided with Baoding support 2; described base is quality of rubber materials; in order to buffer in experimentation with impulsive force when contacting between experimental bench, Protection platform and Baoding support.
Described Baoding support 2 includes one for placing the triangular prism 21 of rat body and one for placing cuboid 22 two parts of rat head, the right-angle surface of described cuboid 22 and triangular prism 21 adjoins, the cross section of this Baoding support 2 is overall at right angles trapezoidal, described Baoding support is stainless steel, wooden or lucite material, supporting bable tops when fixing as rat.
Baoding bracket clamp is connected on base, can be convenient for changing;Can be adhesively fixed with base with Baoding support and be connected.
Leading flank and trailing flank at cuboid are respectively provided with fixing crab-bolt 3, this fixing crab-bolt 3 is near triangular prism 21, animal captures the handedness of people for convenience, leading flank and trailing flank at cuboid are respectively provided with fixing crab-bolt, generally 3-5, the mode can welded fixing crab-bolt or screw is fixed on cuboid side, and elasticity with fixing line can be adjusted flexibly.
Also including 2 fixing lines 4, this fixing line 4 is for being fixed the foreleg of rat respectively;Described fixing line is the ball of string that cotton thread or nylon wire etc. are soft, comfortable, be easy to knotting and untwisting, is typically formed by two in a sleeve fixture mechanism, and all rolling in use for each is that two-wire uses, a diameter of 1.5-2.5 mm.Described fixing line, wherein one end of a fixing line is fixed in fixing crab-bolt, and the other end dissociates, for beating a forelimb wrist of unijunction Baoding rat;Another fixing line two ends are all free, and one end is for beating unijunction Baoding rat another forelimb wrist, and the other end is drawn by Baoding personnel when blood sampling, and rat posture and position can be adjusted flexibly.
Also including headgear 5, the tubular in hollow for the described headgear 5, one end is openend 7, and one end is blind end 6, and described blind end 6 is provided with spiracle 13, and bore dia is 0.3-0.5 cm;Headgear external diameter is 5-6 cm, and headgear wall thickness is 1-2 mm;Openend 7 is divided into fixed page 12 and active page 8 by crack 11, is provided with gear I9, II 10 two gears of gear in fixed page 12, is carried out the adjustment of opening diameter by Compressive activities page 8, can accomplish the abundant exposure of the comfort level behind rat Baoding and blood sampling site.
Described headgear adjusts rat head position and orientation for Nurses and protects Nurses not bitten use by rat simultaneously.Headgear is the tubular of hollow, uses PVC material, and described blind end spiracle is provided with 2-5, preferably 3;Openend is divided into fixed page and active page by crack, be provided with gear I(in fixed page and be suitable for female or below 250g), gear II (being suitable for male or more than 250g) two is with reference to gears, the adjustment of opening diameter can be carried out by Compressive activities page, so that rat head can safe be fixed, keep again comfort level.
This rat jugular sinus fixing device for sampling blood of the present utility model can be by 2 experimenter's compounding practices, wherein 1 entitled Baoding personnel, another 1 entitled Nurses.During operation, Baoding personnel are pressed corresponding operating specification and captures rat (singlehanded);It is left rat that Nurses both hands hold fixing line respectively, right fore is beaten unijunction and is fixed, by a line A(wherein line) the other end be hung on the fixing crab-bolt of side, then by another line of line B() the other end meet at the hand that Baoding personnel do not grab rat, controlled the position of rat by experimenter by the position of tricing line B and elasticity, general optimal position is that rat becomes " cross " type to lie low on the support of Baoding (head is upward), two forelimbs are in alignment and vertical with trunk, the hand capturing rat presses arm under support inclined-plane, Baoding, rat is made to be dorsal position and fully expose thorax;Being held the embedding firmly rat head of headgear, pressing active page to correct position (such as gear I or gear II), degree of tightness appropriateness by Nurses, suitably tilting to side and rotate, now Rats With Unilateral jugular sinus fully exposes, and can be carried out puncture blood collecting by Nurses.Depending on blood sampling volume is according to requirement of experiment, after blood sampling, press lightly on hemostasis, unclamp fixing line.
Claims (10)
1. a rat jugular sinus fixing device for sampling blood, including base, it is characterised in that described base is provided with Baoding support;Described Baoding support includes one, and for placing the triangular prism of rat body and one, for placing cuboid two parts of rat head, the right-angle surface of described cuboid and triangular prism adjoins, and the cross section of this Baoding support is overall at right angles trapezoidal;Leading flank and trailing flank at cuboid are respectively provided with fixing crab-bolt, and this fixing crab-bolt is near triangular prism;Also including 2 fixing lines, this fixing line is for being fixed the foreleg of rat respectively;Also including headgear, described headgear is the tubular of hollow, and one end is openend, and one end is blind end, and described blind end is provided with spiracle, and bore dia is 0.3-0.5cm;Headgear external diameter is 5-6cm, and headgear wall thickness is 1-2mm;Openend is divided into fixed page and active page by crack, is provided with I, II two gears in fixed page, is carried out the adjustment of opening diameter by Compressive activities page.
2. rat jugular sinus fixing device for sampling blood according to claim 1, it is characterised in that described base is quality of rubber materials.
3. rat jugular sinus fixing device for sampling blood according to claim 1, it is characterised in that described Baoding bracket clamp is connected on base, or described Baoding support is adhesively fixed with base and is connected.
4. rat jugular sinus fixing device for sampling blood according to claim 1, it is characterised in that described Baoding support is stainless steel, wooden or lucite material.
5. rat jugular sinus fixing device for sampling blood according to claim 1, it is characterised in that described fixing crab-bolt is 3-5.
6. rat jugular sinus fixing device for sampling blood according to claim 5, it is characterised in that described fixing crab-bolt is 3.
7. rat jugular sinus fixing device for sampling blood according to claim 1, it is characterised in that described fixing line is cotton thread or nylon wire, and fixing linear diameter is 1.5-2.5mm.
8. rat jugular sinus fixing device for sampling blood according to claim 1, it is characterised in that described fixing line, wherein one end of a fixing line is fixed in fixing crab-bolt, and the other end dissociates, for beating the forelimb wrist that unijunction fixes rat;Another fixing line two ends are all free, and rat another forelimb wrist is fixed for beating unijunction in one end, and the other end is drawn by Baoding personnel when blood sampling, and rat posture and position are adjusted flexibly.
9. rat jugular sinus fixing device for sampling blood according to claim 1, it is characterised in that described headgear uses PVC material, described blind end spiracle is provided with 2-5.
10. rat jugular sinus fixing device for sampling blood according to claim 9, it is characterised in that described blind end spiracle is provided with 3.
Priority Applications (1)
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CN201620182861.0U CN205612584U (en) | 2016-03-10 | 2016-03-10 | Rat jugular vein hole blood sampling fixing device |
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CN201620182861.0U CN205612584U (en) | 2016-03-10 | 2016-03-10 | Rat jugular vein hole blood sampling fixing device |
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CN201620182861.0U Expired - Fee Related CN205612584U (en) | 2016-03-10 | 2016-03-10 | Rat jugular vein hole blood sampling fixing device |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105796205A (en) * | 2016-03-10 | 2016-07-27 | 济南大学 | Fixing device for collecting blood of jugular venous sinus of rattus norvegicus |
-
2016
- 2016-03-10 CN CN201620182861.0U patent/CN205612584U/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105796205A (en) * | 2016-03-10 | 2016-07-27 | 济南大学 | Fixing device for collecting blood of jugular venous sinus of rattus norvegicus |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20161005 Termination date: 20180310 |
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CF01 | Termination of patent right due to non-payment of annual fee |