CN205517734U

CN205517734U - High -efficient reation kettle is used in biological medicine preparation

Info

Publication number: CN205517734U
Application number: CN201620187542.9U
Authority: CN
Inventors: 史薇; 李庆宁; 刘冰洋
Original assignee: Ningbo University
Current assignee: Ningbo University
Priority date: 2016-03-12
Filing date: 2016-03-12
Publication date: 2016-08-31
Anticipated expiration: 2026-03-12

Abstract

The utility model discloses a high -efficient reation kettle is used in biological medicine preparation, including the cauldron body, the external wall of cauldron coats and is stamped the polyurethane layer, is equipped with first feed inlet at cauldron body upside left end, and cauldron body upside right -hand member is equipped with the second feed inlet, all is equipped with first solenoid valve on first feed inlet and the second feed inlet, is equipped with the controlling means who adjusts first solenoid valve degree of opening and shutting on reation kettle, is equipped with the stirring pivot in that internal of cauldron is vertical, the utility model discloses high -efficient reation kettle is used in biological medicine preparation, but according to actual need, it is automatic accurate reinforced, still improve reation kettle's wearability, anti -impact, cracking resistance and thermal insulation performance, the cooling is water on introducing the condenser with steam, flow back, this internal decompression of reation kettle simultaneously is through exhaust pump control system, and convenient for operation, and can be even with the material intensive mixing, the reaction thoroughly, overcome because of reaction material's the extrinsic cycle influence to the constancy of temperature, it is invariable relatively to keep the temperature, remove convenient and fast in addition, noise at work is low.

Description

Highly effective reaction still is used in a kind of biological medicine preparation

Technical field

This utility model relates to a kind of biopharmaceutical production facility, and highly effective reaction still is used in specifically a kind of biological medicine preparation.

Background technology

In the production process of biological medicine, it is frequently necessary to use reactor, reactor makes it enter reaction for different materials carries out mixing, reactor carries out structure design and the parameter configuration of container according to different process conditions demands, design condition, process, check and manufacture, checking and accepting and need according to Its Relevant Technology Standards, to realize the heating of technological requirement, to evaporate, cool down and the mixture response function of low high speed.Existing reactor needs hand stock, cannot accurately feed, have impact on the production efficiency of biological medicine, when carrying out some reaction, needs are carried out reaction vapor cooling for reflux constantly, existing reactor does not the most have such function, existing agitating device is when stirring, owing to the horizontal level of stirring paddle is relatively fixed, stirring mixing is usually carried out on a horizontal plane, being unfavorable for the mixing of stirring paddle upper-lower position material, whether material can sufficiently carry out reaction depends on that can agitating device stir.

Utility model content

The purpose of this utility model is to provide a kind of biological medicine preparation highly effective reaction still, with the problem solving to propose in above-mentioned background technology.

For achieving the above object, the following technical scheme of this utility model offer:

nullHighly effective reaction still is used in a kind of biological medicine preparation，Including kettle，It is coated with layer of polyurethane on described kettle outer wall，On the upside of kettle, left end is provided with the first charging aperture，On the upside of kettle, right-hand member is provided with the second charging aperture，It is designed with the first electromagnetic valve on first charging aperture and the second charging aperture，Reactor is provided with the control device of regulation the first electromagnetic valve opening degree，It is provided with stirring shaft at kettle inner vertical，Stirring shaft outer wall is provided with stirring paddle，Stirring shaft top passes outside kettle and is connected with driving motor，Drive and be provided with silencer cover outside motor，Described kettle left side wall top is provided with steam (vapor) outlet，It is provided with seal closure in steam (vapor) outlet periphery，Condenser is connected by pipeline on steam (vapor) outlet，On the left of kettle, upper end is also associated with return duct，The port of export connecting tee pipe of return duct left end，The other two ends of tee T connect air pump and condenser respectively，Air pump and condenser are connected on the pipeline of tee T be designed with the second control valve，Batch mixing heater it is additionally provided with on described kettle，Batch mixing heater includes return duct、Fluid groove and circulating pump，Return duct is arranged on upper position on the right side of kettle，Circulating pump is arranged in series on the right side of the cabinet on the return duct in centre position，The upper end of return duct extends horizontally to the inside of kettle，One ring pipe of return duct end UNICOM，The downside outer wall of ring pipe is evenly distributed with hole for water spraying，Ring pipe is arranged on the top of the internal stirring paddle of kettle，Return duct be connected with stage casing sidewall on the right side of kettle one section is in coil-like，And be arranged in fluid groove，Return duct is provided with electrical heating wire outside a segment pipe of right side wall on the upside of kettle，Described return duct is provided with static mixer，On the downside of cabinet, surrounding connects roller by supporting leg.

As further program of the utility model: the thickness of described layer of polyurethane is 8-15mm.

As further program of the utility model: described stirring paddle is provided with four groups the most altogether.

As this utility model further scheme: the material of described silencer cover is sound-proof damping felt.

Compared with prior art, the beneficial effects of the utility model are: the cruel layer of poly-ammonia has the advantages such as good tensile strength, tearing toughness, resistance to impact, wearability, weatherability, hydrolytic resistance, sound insulaton and oil resistivity, the wearability of kettle, resistance to impact, cracking resistance and heat-insulating property can be increased, control device can be automatically adjusted the opening degree of the first electromagnetic valve according to actual needs and complete the most accurately charging, automaticity is high, silencer cover can effectively reduce noise when driving motor work, improves the working environment of operative employee；The steam (vapor) outlet of kettle is connected on condenser, introduces steam into and is cooled to water on condenser, refluxes, and the decompression of kettle is by exhaust pump control simultaneously, easy to operate, practical；The material of kettle lower end Yu upper end is circulated transport flow by return duct by batch mixing heater, fully ensure that material mix homogeneously, the electrical heating wire arranged near one end of kettle upper end sidewall on return duct is to maintain reaction mass temperature in return duct consistent with in kettle, overcome the impact on temperature constant of the outer circulation because of reaction mass, keep temperature relative constancy, effectively raise reaction efficiency, ensure reactant quality, the setting of roller makes reactor conveniently moving quick, and convenience is high.

Accompanying drawing explanation

Fig. 1 is the structural representation of biological medicine preparation highly effective reaction still.

Detailed description of the invention

Below in conjunction with the accompanying drawing in this utility model embodiment, the technical scheme in this utility model embodiment is clearly and completely described, it is clear that described embodiment is only a part of embodiment of this utility model rather than whole embodiments.Based on the embodiment in this utility model, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, broadly fall into the scope of this utility model protection.

nullRefer to Fig. 1，In this utility model embodiment，Highly effective reaction still is used in a kind of biological medicine preparation，Including kettle 1，It is coated with layer of polyurethane 2 on described kettle 1 outer wall，The thickness of described layer of polyurethane 2 is 8-15mm，On the upside of kettle 1, left end is provided with the first charging aperture 3，On the upside of kettle 1, right-hand member is provided with the second charging aperture 4，It is designed with the first electromagnetic valve 5 on first charging aperture 3 and the second charging aperture 4，Reactor is provided with regulation the first electromagnetic valve and opens 5 right control devices，It is provided with stirring shaft 6 at kettle 1 inner vertical，Stirring shaft 6 outer wall is provided with stirring paddle 7，Described stirring paddle about 7 is provided with four groups altogether，Stirring shaft 7 top passes outside kettle 1 and is connected with driving motor 8，Drive and be provided with silencer cover 9 outside motor 8，The material of described silencer cover 9 is sound-proof damping felt，The cruel layer of poly-ammonia has good tensile strength、Tearing toughness、Resistance to impact、Wearability、Weatherability、Hydrolytic resistance、The advantage such as sound insulaton and oil resistivity，The wearability of kettle 1 can be increased、Resistance to impact、Cracking resistance and heat-insulating property，Control device can be automatically adjusted the opening degree of the first electromagnetic valve 5 according to actual needs and complete the most accurately charging，Automaticity is high，Silencer cover 9 can effectively reduce noise when driving motor 8 to work，Improve the working environment of operative employee；Described kettle 1 left side wall top is provided with steam (vapor) outlet 10, it is provided with seal closure in steam (vapor) outlet 10 periphery, condenser 11 is connected by pipeline on steam (vapor) outlet 10, on the left of kettle 1, upper end is also associated with return duct 12, the port of export connecting tee pipe of return duct 12 left end, the other two ends of tee T connect air pump 13 and condenser 11 respectively, air pump 13 and condenser 11 are connected on the pipeline of tee T be designed with the second control valve 14, the steam (vapor) outlet 10 of kettle 1 is connected on condenser 11, introduce steam into and be cooled to water on condenser 11, reflux, the decompression of kettle 1 simultaneously is controlled by exhaust pump 13, easy to operate, practical；nullIt is additionally provided with batch mixing heater on described kettle 1，Batch mixing heater includes return duct 18、Fluid groove 20 and circulating pump 21，Return duct 18 is arranged on upper position on the right side of kettle 1，Circulating pump 21 is arranged in series on the right side of the cabinet 1 on the return duct 18 in centre position，The upper end of return duct 18 extends horizontally to the inside of kettle 1，One ring pipe 15 of return duct 18 end UNICOM，The downside outer wall of ring pipe 15 is evenly distributed with hole for water spraying，Ring pipe 15 is arranged on the top of the internal stirring paddle 7 of kettle 1，Return duct 18 be connected with stage casing sidewall on the right side of kettle 1 one section is in coil-like，And be arranged in fluid groove 20，Return duct 18 is provided with electrical heating wire 17 outside a segment pipe 16 of right side wall on the upside of kettle 1，Described return duct 18 is provided with static mixer 19，On the downside of cabinet 1, surrounding connects roller 23 by supporting leg 22，The material of kettle lower end Yu upper end is circulated transport flow by return duct 18 by batch mixing heater，Fully ensure that material mix homogeneously，The electrical heating wire 17 arranged near one end of kettle upper end sidewall on return duct 18 is to maintain reaction mass temperature in return duct 18 consistent with in kettle，Overcome the impact on temperature constant of the outer circulation because of reaction mass，Keep temperature relative constancy，Effectively raise reaction efficiency，Ensure reactant quality，The setting of roller 23 makes reactor conveniently moving quick，Convenience is high；Highly effective reaction still is used in the preparation of this utility model biological medicine, can be according to actual needs, the most accurately charging, also improve the wearability of reactor, resistance to impact, cracking resistance and heat-insulating property, introduce steam into and on condenser, be cooled to water, reflux, the intrinsic decompression of simultaneous reactions still is by exhaust pump control, easy to operate, and material can be sufficiently mixed uniformly, reaction is thoroughly, overcome the impact on temperature constant of the outer circulation because of reaction mass, keeping temperature relative constancy, additionally conveniently moving is quick, and operating noise is low.

Operation principle of the present utility model is: the cruel layer of poly-ammonia has the advantages such as good tensile strength, tearing toughness, resistance to impact, wearability, weatherability, hydrolytic resistance, sound insulaton and oil resistivity, the wearability of kettle 1, resistance to impact, cracking resistance and heat-insulating property can be increased, control device can be automatically adjusted the opening degree of the first electromagnetic valve 5 according to actual needs and complete the most accurately charging, automaticity is high, silencer cover 9 can effectively reduce noise when driving motor 8 to work, and improves the working environment of operative employee；The steam (vapor) outlet 10 of kettle 1 is connected on condenser 11, introduces steam into and is cooled to water on condenser 11, refluxes, and the decompression of kettle 1 simultaneously is controlled by exhaust pump 13, easy to operate, practical；The material of kettle lower end Yu upper end is circulated transport flow by return duct 18 by batch mixing heater, fully ensure that material mix homogeneously, the electrical heating wire 17 arranged near one end of kettle upper end sidewall on return duct 18 is to maintain reaction mass temperature in return duct 18 consistent with in kettle, overcome the impact on temperature constant of the outer circulation because of reaction mass, keep temperature relative constancy, effectively raise reaction efficiency, ensure reactant quality, the setting of roller 23 makes reactor conveniently moving quick, and convenience is high.

It is obvious to a person skilled in the art that this utility model is not limited to the details of above-mentioned one exemplary embodiment, and in the case of without departing substantially from spirit or essential attributes of the present utility model, it is possible to realize this utility model in other specific forms.Therefore, no matter from the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, scope of the present utility model is limited by claims rather than described above, it is intended that all changes fallen in the implication of equivalency and scope of claim included in this utility model.Should not be considered as limiting involved claim by any reference in claim.

In addition, it is to be understood that, although this specification is been described by according to embodiment, but the most each embodiment only comprises an independent technical scheme, this narrating mode of description is only for clarity sake, description should can also be formed, through appropriately combined, other embodiments that it will be appreciated by those skilled in the art that as an entirety, the technical scheme in each embodiment by those skilled in the art.

Claims

null1. highly effective reaction still is used in a biological medicine preparation，Including kettle，It is characterized in that，It is coated with layer of polyurethane on described kettle outer wall，On the upside of kettle, left end is provided with the first charging aperture，On the upside of kettle, right-hand member is provided with the second charging aperture，It is designed with the first electromagnetic valve on first charging aperture and the second charging aperture，Reactor is provided with the control device of regulation the first electromagnetic valve opening degree，It is provided with stirring shaft at kettle inner vertical，Stirring shaft outer wall is provided with stirring paddle，Stirring shaft top passes outside kettle and is connected with driving motor，Drive and be provided with silencer cover outside motor，Described kettle left side wall top is provided with steam (vapor) outlet，It is provided with seal closure in steam (vapor) outlet periphery，Condenser is connected by pipeline on steam (vapor) outlet，On the left of kettle, upper end is also associated with return duct，The port of export connecting tee pipe of return duct left end，The other two ends of tee T connect air pump and condenser respectively，Air pump and condenser are connected on the pipeline of tee T be designed with the second control valve，Batch mixing heater it is additionally provided with on described kettle，Batch mixing heater includes return duct、Fluid groove and circulating pump，Return duct is arranged on upper position on the right side of kettle，Circulating pump is arranged in series on the right side of the cabinet on the return duct in centre position，The upper end of return duct extends horizontally to the inside of kettle，One ring pipe of return duct end UNICOM，The downside outer wall of ring pipe is evenly distributed with hole for water spraying，Ring pipe is arranged on the top of the internal stirring paddle of kettle，Return duct be connected with stage casing sidewall on the right side of kettle one section is in coil-like，And be arranged in fluid groove，Return duct is provided with electrical heating wire outside a segment pipe of right side wall on the upside of kettle，Described return duct is provided with static mixer，On the downside of cabinet, surrounding connects roller by supporting leg.
Biological medicine preparation highly effective reaction still the most according to claim 1, it is characterised in that the thickness of described layer of polyurethane is 8-15mm.
Biological medicine preparation highly effective reaction still the most according to claim 1, it is characterised in that described stirring paddle is provided with four groups the most altogether.
Biological medicine preparation highly effective reaction still the most according to claim 1, it is characterised in that the material of described silencer cover is sound-proof damping felt.