CN205484226U - A device for diagnosing human helicobacter pylori infects - Google Patents
A device for diagnosing human helicobacter pylori infects Download PDFInfo
- Publication number
- CN205484226U CN205484226U CN201620257299.3U CN201620257299U CN205484226U CN 205484226 U CN205484226 U CN 205484226U CN 201620257299 U CN201620257299 U CN 201620257299U CN 205484226 U CN205484226 U CN 205484226U
- Authority
- CN
- China
- Prior art keywords
- helicobacter pylori
- pipeline
- way valve
- human body
- ammonia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Abstract
The utility model discloses a device for diagnosing human helicobacter pylori infects, the device include human expiration collection system and detecting system, human expiration collection system is including sampling bag, diaphragm pump, gas flowmeter and medicament pond, sampling bag, diaphragm pump, gas flowmeter and medicament pond loop through the pipe connection, the medicament pond in be equipped with ammonia and catch the agent, sampling bag and pipeline between detachable the connection. Ammonia during the device can effectively catch, fixed human body is exhaled to realize quick accurate measuring of ammonia, thereby realize diagnosing human hp to infect more accurate, more high -efficiently, when reducing the medicament production cost, eliminated medicament toxic and side effect's hidden danger in the past.
Description
Technical field
This utility model relates to a kind of device diagnosing human body helicobacter pylori infections；It is specifically related to one and utilizes people
Body takes common urea electuary, discharges ammonia by carbamide with human body helicobacter pylori mark urease effect,
Again with the ammonia in ammonia trapping agent capture sample, use the device of the fixing ammonia of ion chromatographic method detection；Pass through
Ammonia level in human exhaled breath is diagnosed human body helicobacter pylori infections degree, belongs to medical instruments field.
Background technology
Helicobacter pylori (being called for short Hp) is one of the most modal pathogen, the sense in population of China
Dye rate is up to 60%, and annual new infeetioa case is more than 12,000,000 people.The duodenum of the most about more than 90% is burst
Infections, the gastric ulcer of more than 70%, the Patients with Chronic Gastritis of more than 60% exist Hp to be infected, World Health Organization (WHO)
It is defined as the first kind carcinogen of gastric cancer.
At present, the method system that existing detection Hp infects mainly has gastroscope detection system, immunology detection body
System, polymerase chain reaction detection system, saliva method detection system, urease detection system,13C/14C carbamide
Breath test detection system etc..Above system has or brings misery or detection accuracy, ageing to person under inspection
The defects such as poor or toxic side effect.
Utility model content
In order to solve the defect in prior art, the detection system of helicobacter pylori infections existed, this utility model
Purpose be to provide one effectively to capture, fixing human exhale in ammonia, and realize ammonia quick and precisely
The device of detection, thus realize more accurately, more efficiently diagnosing human body Hp and infect, produce into reducing medicament
While Ben, eliminate the hidden danger of conventional medicament toxic and side effects.
In order to realize above-mentioned technical purpose, this utility model provides a kind of for diagnosing human body Helicobacter pylori
The device of dye, this device includes human exhaled breath's acquisition system and detecting system；Described human exhaled breath's acquisition system bag
Include sampler bag, membrane pump, gas flowmeter and medicament pond；Described sampler bag, membrane pump, gas flowmeter and
Medicament pond passes sequentially through pipeline and connects；Described medicament pond is built with ammonia trapping agent；Described sampler bag and pipeline
Between detachable connection.
Preferably scheme, sampler bag is connected with described pipeline by three-way valve.
Preferably scheme, three-way valve includes human exhaled breath's sample intake passage and flushing channel.
Preferably scheme, detecting system is chromatography of ions detector.
More preferably scheme, chromatography of ions detector includes automatic sampler, chromatographic column, high-pressure pump, leacheate
Tank, waste liquid tank and electric conductivity detector.
Preferably scheme, chromatography of ions detector is provided with six-way valve；Described automatic sampler accesses institute by pipeline
State six-way valve；Described drip washing flow container and described high-pressure pump pass sequentially through pipeline and access described six-way valve；Described waste liquid
Tank is picked out from described six-way valve by pipeline；Described chromatographic column and described electric conductivity detector pass sequentially through pipeline from institute
State six-way valve to pick out.
Preferably scheme, drip washing flow container is built with leacheate.
Preferably scheme, chromatography of ions detector also includes needle-like sample introduction head.
The ammonia trapping agent that this utility model uses is mainly acidic materials, as including at least HNO3、H3PO4、
HCl、H2SO4, at least one acid composition in TGA.
The sampler bag general volume 250mL that this utility model relates to, sampler bag uses polyvinyl-fluoride complex
Material is made, and sampler bag is provided with supporting threaded cap.
This utility model for diagnosing the principle of human body helicobacter pylori infections is: utilize urea reagent to imprison with human body
Helicobacter pylori mark urease effect release ammonia, then capture the ammonia of release with ammonia trapping agent and realize ammonia
The fixing ammonium salt that generates, finally uses ion chromatographic method accurately to detect ammonium salt, such that it is able to be diagnosed to be human body pylorus
Pylori (Hp) infection degree.
Hinge structure, the Advantageous Effects that this utility model brings:
1) by the device of diagnosis human body helicobacter pylori infections can integration realize ammonia collection, fixing,
Detection, energy is quick, accurate, Sensitive Detection goes out ammonia level in human exhaled breath, and passes through human exhaled breath further
The content of middle ammonia diagnoses human body helicobacter pylori infections degree.
2) device of diagnosis human body helicobacter pylori infections is simple, and the suitability is strong, and human body is carried out testing in vitro,
And avoid use harmful chemicals or bring patient misery, beneficially popularization and application.
Accompanying drawing explanation
[Fig. 1] is the apparatus structure sketch for diagnosing human body helicobacter pylori infections:
Wherein, 1 is medicament pond, and 2 is automatic sampler, and 3 is gas flowmeter, and 4 is needle-like sample introduction head, 5 be every
Membrane pump, 6 is three-way valve, and 7 is sampler bag, and 8 is waste liquid tank, and 9 is drip washing flow container, and 10 is chromatographic column；11
For six-way valve, 12 is electric conductivity detector, and 13 is high-pressure pump, and 14 is flushing channel, and 15 is human exhaled breath's sample introduction
Passage.
Detailed description of the invention
Following example are intended to combine accompanying drawing and further illustrate this utility model content rather than this practicality now
Novel content.
This utility model is for diagnosing the device of human body helicobacter pylori infections as shown in Figure 1.This device mainly wraps
Include human exhaled breath's acquisition system and detecting system two parts.
Human exhaled breath's acquisition system includes sampler bag 7, membrane pump 5, gas flowmeter 3 and medicament pond 1；Described
Sampler bag 7, membrane pump 5, gas flowmeter 3 and medicament pond 1 pass sequentially through pipeline and connect；Wherein, sampling
Bag 7 is connected by three-way valve 6 is detachable with pipeline.Medicament pond 1 is used built with ammonia trapping agent, ammonia trapping agent
Breathing ammonia in sample in efficiently catching, ammonia trapping agent is mainly acidic materials, can be with the ammonia in human exhaled breath
Reaction generates ammonium salt.Gas flowmeter 3 is for regulation and stably breathes sample flow velocity.Membrane pump 5 is adopted as expiration
The power source of collecting system, is used for manufacturing pressure reduction, promotes human exhaled breath's flowing.Three-way valve 6 includes that human exhaled breath enters
Sample passage 15 and flushing channel 14, sample intake passage 15 is connected with sampler bag 7.
Detecting system is chromatography of ions detector.Chromatography of ions detector include automatic sampler 2, chromatographic column 10,
High-pressure pump 13, drip washing flow container 9, waste liquid tank 8 and electric conductivity detector 12.Chromatography of ions detector is provided with clematis stem
Valve 11；Automatic sampler 2 accesses six-way valve 11 by pipeline；Described drip washing flow container 9 is with high-pressure pump 13 successively
Six-way valve 11 is accessed by pipeline；Waste liquid tank 8 is picked out from six-way valve 11 by pipeline；Described chromatographic column 10
Pass sequentially through pipeline with described electric conductivity detector 12 to pick out from six-way valve 11.Automatic sampler 2 is for ion color
Spectrum multichannel sample introduction.Needle-like sample introduction head 4 is for chromatography of ions multi-channel sampling.Six-way valve 11 is for ion color
Spectrum sampling and sample introduction.Waste liquid tank 8 is used for reclaiming ion chromatography system waste liquid.Drip washing flow container 9 is equipped with as ion
The flowing phase of chromatograph cation detection, has the auxiliary function such as sample introduction and purging system.Chromatographic column 10 is for sample
The separation of heterogeneity in product；Electric conductivity detector 12 is used for detecting in sample different cation；High-pressure pump 13
For chromatography of ions as conveying detection sample and the power source of leacheate.
This utility model device is for the method diagnosing human body helicobacter pylori infections degree:
1, human exhaled breath is gathered by sampler bag, as blank sample；
2, human body takes carbamide electuary by oral way；After a period of time, gather human body by sampler bag and exhale
Gas, as testing sample.
3, human exhaled breath's sample introduction of the sampler bag and human exhaled breath's acquisition system three-way valve of collecting human exhaled breath is led to
Road connects, with membrane pump as power source, by breathing sample in sampler bag through three-way valve suction gas flowmeter, and with
Stabilized speed is passed through in medicament pond, is reacted with the ammonia in human exhaled breath by the ammonia trapping agent in medicament pond, raw
Become ammonium salt solution.
4, the ammonium salt solution generated is by needle-like sample introduction head from automatic sampler sample introduction, enters six-way valve and with pouring
Washing liquid is forced into chromatographic column by high-pressure pump, carries out chromatographic column separation, and separator eventually arrives at electric conductivity detector and enters
Row detection, obtains NH in sample4 +Content, and then calculate ammonia content in breathing sample.
5, according to the principle of urea reagent with human body helicobacter pylori mark urease effect release ammonia, knot
Close ammonia level in the human exhaled breath recorded, diagnose human body helicobacter pylori infections degree.
Claims (6)
1. the device being used for diagnosing human body helicobacter pylori infections, it is characterised in that: include that human exhaled breath gathers
System and detecting system；Described human exhaled breath's acquisition system includes sampler bag (7), membrane pump (5), gas stream
Gauge (3) and medicament pond (1)；Described sampler bag (7), membrane pump (5), gas flowmeter (3) and medicine
Agent pond (1) passes sequentially through pipeline and connects；Described medicament pond (1) is built with ammonia trapping agent；Described sampling
Detachable it is connected between bag (7) and pipeline.
Device for diagnosing human body helicobacter pylori infections the most according to claim 1, it is characterised in that:
Described sampler bag (7) is connected with described pipeline by three-way valve (6)；Described three-way valve (6) includes people
Body expiration sample intake passage (15) and flushing channel (14).
Device for diagnosing human body helicobacter pylori infections the most according to claim 1, it is characterised in that:
Described detecting system is chromatography of ions detector.
Device for diagnosing human body helicobacter pylori infections the most according to claim 3, it is characterised in that:
Described chromatography of ions detector includes automatic sampler (2), chromatographic column (10), high-pressure pump (13), drip washing
Flow container (9), waste liquid tank (8) and electric conductivity detector (12).
Device for diagnosing human body helicobacter pylori infections the most according to claim 4, it is characterised in that:
Described chromatography of ions detector is provided with six-way valve (11)；Described automatic sampler (2) accesses institute by pipeline
State six-way valve (11)；Described drip washing flow container (9) and described high-pressure pump (13) pass sequentially through pipeline and access described
Six-way valve (11)；Described waste liquid tank (8) is picked out from described six-way valve (11) by pipeline；Described chromatographic column
(10) pass sequentially through pipeline with described electric conductivity detector (12) to pick out from described six-way valve (11).
Device for diagnosing human body helicobacter pylori infections the most according to claim 5, it is characterised in that:
Described drip washing flow container (9) is built with leacheate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620257299.3U CN205484226U (en) | 2016-03-30 | 2016-03-30 | A device for diagnosing human helicobacter pylori infects |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620257299.3U CN205484226U (en) | 2016-03-30 | 2016-03-30 | A device for diagnosing human helicobacter pylori infects |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205484226U true CN205484226U (en) | 2016-08-17 |
Family
ID=56649042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620257299.3U Expired - Fee Related CN205484226U (en) | 2016-03-30 | 2016-03-30 | A device for diagnosing human helicobacter pylori infects |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205484226U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110567654A (en) * | 2019-09-12 | 2019-12-13 | 安徽养和医疗器械设备有限公司 | Expiration detection system |
-
2016
- 2016-03-30 CN CN201620257299.3U patent/CN205484226U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110567654A (en) * | 2019-09-12 | 2019-12-13 | 安徽养和医疗器械设备有限公司 | Expiration detection system |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170329 Address after: 410600 Hunan Province, Changsha high tech Development Zone, No. 459 East Road, Pine Road, the extension of the village of red building, building 1460C, room Patentee after: KANICHI RES SERVICES LTD. Address before: 518000 Guangdong city of Shenzhen province Qianhai Shenzhen Hong Kong cooperation zone before Bay Road No. 1 building 201 room A Patentee before: Shenzhen Sanxiang Biological Sensing Technology Co., Ltd. |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160817 Termination date: 20180330 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |