CN205388543U - Device of metabolite during constraint of collection rat - Google Patents
Device of metabolite during constraint of collection rat Download PDFInfo
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- CN205388543U CN205388543U CN201620136043.7U CN201620136043U CN205388543U CN 205388543 U CN205388543 U CN 205388543U CN 201620136043 U CN201620136043 U CN 201620136043U CN 205388543 U CN205388543 U CN 205388543U
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- rat
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- flat board
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Abstract
The utility model provides a device of metabolite during constraint of collection rat, put including support, the inclined that inclines a constraint section of thick bamboo and level on the support are placed metabolite collector in the support. The utility model provides a device of metabolite during constraint of collection rat can gather the metabolite of rat during fettering, guarantees for research rat metabolism studies at animal body of organism metabolic process and metabolic mechanism and various medicine and nutrients in the middle of the constraint process provides the experiment, has changed the blow vent structure simultaneously, has improved the air smoothness nature of rat during fettering, has avoided rat oxygen deficiency and hyperthemia's phenomenon emergence.
Description
Technical field
This utility model relates to animal metabolism thing acquisition technique field, is specifically related to a kind of gather the device of metabolite during rat constraint.
Background technology
In field of biomedical research, zoopery is a kind of common medical experiment, rat, as one of animal that diet is not required, is ideal laboratory animal, and the existing medical experiment for rat mainly has metabolism of rat thing collection experiment and rat constraint experiment.
Metabolism of rat thing collection generally uses rat metabolism cage and collects the urine and feces discharged under rat naturalness, can the D&E of rat be carried out quantitatively, and fecaluria can separate to a certain extent.On this basis, the internal metabolism that can carry out various medicine and nutrient substance is studied.Rat restraint device cylinder is also conventional a kind of experimental provision, mainly by using this device, the activity of rat is limited.This device utilizes rat to like the characteristic got into the cave, and makes rat creep in special scalable constraint cylinder.Prolonged and repeated constraint is mainly by the body limitation of activity making rat, so that it produces psychology and Behavioral change such as struggling, irritable, angry, depressed, desperate, cause the dysfunction of body, thus causing the generation of body and mental fatigue, this device is often used in the chronic fatigue model setting up rat.
But, along with the increase of human body diseases kind and cause of disease complexity, the metabolism group experiment of confirmed fatigue, the metabolism group experiment of depression and the metabolism group experiment etc. of infantile autism have become as the frontier nature research experiment of current medical science, field of biology.The metabolite that they typically require during rat is fettered is acquired, and then the metabolism in animal body carrying out organism metabolism process in the middle of constraint process, metabolic mechanism and various medicine and nutrient substance is studied.Existing rat metabolism cage can collect the product of metabolism of rat, but can not rat be carried out constraint experiment simultaneously, and although rat can be carried out constraint experiment by conventional rat constraint cylinder, but the metabolite of rat can not be collected, above two experimental provision cannot solve to gather this problem of metabolite during rat fetters, the cylinder blow vent of existing rat constraint simultaneously is little, the easy anoxia of rat.
Utility model content
The purpose of this utility model is the deficiency in order to overcome above-mentioned prior art to exist, there is provided a kind of and gather the device of metabolite during rat fetters, collecting function and the rat constraint function of metabolism of rat thing are gathered, rat metabolite during fettering can be collected, the research of metabolism in animal body for research rat organism metabolism process and metabolic mechanism and various medicine and nutrient substance in the middle of constraint process provides experiment to ensure, change vent constructions simultaneously, improve rat air fluency during fettering, avoid Rats Exposed To Hypoxia and Hyperthermic phenomenon occurs.
To achieve these goals, this utility model provides following technical scheme: a kind of gather the device of metabolite during rat constraint, including support, described support has two side plates vertically placed being parallel to each other, and it is horizontally set between two side plates the first flat board and the second flat board that are parallel to each other, one of them side plate has elongated end upwards, and described elongated end end is provided with draw-in groove, and described first flat board offers hole clipping；
Also include slant setting constraint cylinder on the bracket, cylinder that described constraint cylinder includes having the first nozzle and the second nozzle and be wound in described first nozzle end and there is the filter screen downwardly extending end, described second nozzle end is overlapped on described draw-in groove, the described first nozzle end described hole clipping of traverse, described first nozzle end is fixed with blend stop, and described blend stop is stuck on described first flat board；
Also include the catcher being placed on described second flat board, described catcher includes bayonet socket holder and is fixed on the feces collector on described bayonet socket holder and urine collector, described feces collector abuts with described filter screen end, and described urine collector is just to described first nozzle.
Preferably, described draw-in groove is semicircle orifice, and described hole clipping is circular hole.
Preferably, described constraint cylinder is 30 °-60 ° with the axial angle of described first flat board.
It is highly preferred that the axial angle of described constraint cylinder and described first flat board is 45 °.
Preferably, the cross section of described first nozzle is parallel to described first flat board.
Preferably, described blend stop includes screw and nut, and described screw and nut are respectively arranged with three, uniformly offers three groups of circular holes in the position of the cross section 1-2cm apart from described first nozzle, described screw is through described circular hole and fixes with described nut, and described nut is stuck on described first flat board.
Preferably, described device also includes screw and nut, and described screw and nut are respectively arranged with three, uniformly offers three groups of circular holes in the position of the cross section 1-2cm apart from described second nozzle, and described screw is through described circular hole and fixes with described nut.
Preferably, described bayonet socket holder is have inner chamber cylindric, and described bayonet socket holder surface offers the first circular hole and the second circular hole, and described feces collector is placed in described first circular hole, and described urine collector is placed in described second circular hole.
Preferably, described feces collector is teat glass, test tube mouth abuts described filter screen end, described urine collector includes centrifuge tube and pan, described pan includes pan body and pan neck, described pan body is through the second circular hole and is stuck on the second circular hole, and described pan neck is inserted in described centrifuge tube, and described pan body is just to described hole clipping.
Preferably, the inner chamber of described bayonet socket holder is placed with ice cube.
Preferably, described cylinder internal diameter is 4-6cm, and length is 18-20cm；
Described screen specification is 30-50 order, and length is 13-19cm, and width is 5-8cm；
The diameter of described hole clipping is 5-8cm, and the diameter of described draw-in groove is identical with the internal diameter of described cylinder；
The external diameter of described bayonet socket holder is 8-10cm, is highly 6-10cm；The diameter of described first circular hole is 1.5-2.5cm, and the diameter of described second circular hole is 4-8cm；Described test tube internal diameter is 1-2cm, is highly 8-12cm；Described centrifuge tube volume is 4-6ml, and the internal diameter of described pan body is 6-10cm.
The material of described cylinder and described support is PVC (polrvinyl chloride), and the material of described bayonet socket holder is glass.
The beneficial effects of the utility model are:
(1) compared with tradition rat metabolism cage, constraint cylinder, this device can collect rat metabolite during fettering, and the research of metabolism in animal body for research rat organism metabolism process, metabolic mechanism and various medicine and nutrient substance in the middle of constraint process provides experiment guarantee；(2) constraint cylinder all adopts three screws to fix up and down, can be limited in by rat in constraint cylinder, increase again the draught area of constraint cylinder, improve rat air fluency during fettering, it is to avoid Rats Exposed To Hypoxia and Hyperthermic phenomenon occur；(3) compared with traditional experiment device, this apparatus structure is simple, with low cost, is greatly saved research expenditure.
Accompanying drawing explanation
Fig. 1 gathers the apparatus structure schematic diagram of metabolite during rat fetters for what this utility model embodiment provided；
Fig. 2 is the structural representation of cylinder.
Detailed description of the invention
Below in conjunction with accompanying drawing, detailed description of the invention of the present utility model is further described.Following example are only for clearly illustrating the technical solution of the utility model, and can not limit protection domain of the present utility model with this.
Embodiment 1
This utility model provides and a kind of gathers the device of metabolite during rat constraint, specifically as depicted in figs. 1 and 2, including constraint cylinder 2 on support 1 of support 1, slant setting and the catcher 3 that lies in a horizontal plane in support；Support 1 has two side plates vertically placed being parallel to each other, and it is arranged on the first flat board 11 and the second flat board 12 of parallel placement between two side plates, one of them side plate has elongated end upwards, elongated end end is provided with the semicircle draw-in groove 13 that diameter is 4.5cm, first flat board offers the circular hole clipping 14 that diameter is 7cm, draw-in groove 13 and hole clipping 14 are for fixing constraint cylinder 2, and the axial angle of constraint cylinder and the first flat board is 45 °.
Constraint cylinder 2 includes having the cylinder 21 of the first nozzle 211 and the second nozzle 212, be wound in the first nozzle 211 end and have the filter screen 22 downwardly extending end and be fixed on screw 24 and the nut 25 at cylinder 21 two ends, the cross section of the first nozzle 211 is parallel to the first flat board 11, second nozzle 212 end is overlapped on draw-in groove 13, the first nozzle 211 end traverse hole clipping 14.
Wherein, the internal diameter of cylinder 21 is 4.5cm, length is 18.5cm, cylinder 21 design of minor diameter is to allow rat light activity in bucket, rat is not allowed to turn around, the cross section of the first nozzle 211 is parallel to rat when the first flat board 11 setting can ensure constraint cylinder 2 slant setting and can stand in bucket by horizontal station, stand reliable, and be beneficial to collection metabolite；Uniformly offering three groups of circular holes 23 respectively in the position of the cross section of distance the first nozzle and the cross section 1-2cm of the second nozzle, screw 24 is through circular hole 23 fixing with nut 25, and nut 25 is stuck on the first flat board 11；Three screws 24 of the second nozzle end play sealing effect, preventing rat from running out of constraint cylinder 2, three screws 24 of the first nozzle end also serve as rat hindlimb and step on the cross bar grabbed while playing sealing effect, restriction activities in rats, nut 25 is stuck on the first flat board 11 and prevents constraint cylinder from gliding；Screen specification is 40 orders, and length is 14.5cm, and width is 7cm, and filter screen is used for opening rat feces and urine separation.
Catcher 3 include external diameter be 9cm, highly for the bayonet socket holder 31 of 8cm, feces collector and urine collector, bayonet socket holder 31 surface offers the first circular hole 311 that diameter is 2cm and the second circular hole 312 that diameter is 6cm, is respectively intended to fixing feces collector and urine collector；Feces collector is internal diameter is 1.2cm, highly for the test tube 32 of 10cm, urine collector is made up of the centrifuge tube 34 that the pan 33 that diameter is 8cm and volume are 5mL；Pan 33 includes pan body 331 and pan neck 332, and test tube 32 inserts the first circular hole 311 and is connected on the bottom surface of bayonet socket holder 31, and test tube 32 upper end abuts with filter screen 22 end；Pan body 331 inserts the second circular hole 312 and is stuck on the second circular hole 312, and pan neck 332 inserts centrifuge tube 34, and centrifuge tube 34 lower end is connected on the bottom surface of bayonet socket holder 31, and pan body 331 is just to hole clipping 14；Test tube 32 is used for collecting rat feces, pan 33 and centrifuge tube 34 are used for collecting the urine of rat, and centrifuge tube 34 also has the function measuring volume of urine, it is ensured that experimental result is more accurate, ice cube can also be placed in bayonet socket holder 31, reach the cooling effect to metabolite.
In this embodiment, the material of cylinder 21 and support 1 is PVC, and the material of bayonet socket holder 31 is glass.
When testing, three sealing screws of constraint cylinder upper end can be unclamped, rat (afterbody is down) is put into constraint cylinder, then sealing screw-driving and fixing with nut.Rat excrement particles during fettering, can fall on filter screen, then automatically rolls into test tube, and the urine of rat, filter screen can be passed perpendicularly through, drop in pan, finally flow into centrifuge tube.In bayonet socket holder, it is possible to place ice cube, reach the cooling effect to metabolite.
Embodiment described above is only this utility model preferably detailed description of the invention; protection domain of the present utility model is not limited to this; any those of ordinary skill in the art are in the technical scope that this utility model discloses; simple change or the equivalence of the technical scheme that can become apparent to are replaced, and belong to protection domain of the present utility model.
Claims (10)
1. one kind gathers the device of metabolite during rat fetters, it is characterized in that, including support, described support has two side plates vertically placed being parallel to each other, and it is horizontally set between two side plates the first flat board and the second flat board that are parallel to each other, one of them side plate has elongated end upwards, and described elongated end end is provided with draw-in groove, and described first flat board offers hole clipping；
Also include slant setting constraint cylinder on the bracket, cylinder that described constraint cylinder includes having the first nozzle and the second nozzle and be wound in described first nozzle end and there is the filter screen downwardly extending end, described second nozzle end is overlapped on described draw-in groove, the described first nozzle end described hole clipping of traverse, described first nozzle end is fixed with blend stop, and described blend stop is stuck on described first flat board；
Also include the catcher being placed on described second flat board, described catcher includes bayonet socket holder and is fixed on the feces collector on described bayonet socket holder and urine collector, described feces collector abuts with described filter screen end, and described urine collector is just to described first nozzle.
2. the device of metabolite during collection rat constraint according to claim 1, it is characterised in that described draw-in groove is semicircle orifice, and described hole clipping is circular hole.
3. the device of metabolite during collection rat constraint according to claim 1, it is characterised in that the axial angle of described constraint cylinder and described first flat board is 30 °-60 °.
4. the device of metabolite during collection rat constraint according to claim 3, it is characterised in that the axial angle of described constraint cylinder and described first flat board is 45 °.
5. the device of metabolite during collection rat constraint according to claim 1, it is characterised in that the cross section of described first nozzle is parallel to described first flat board.
6. the device of metabolite during collection rat constraint according to claim 1, it is characterized in that, described blend stop includes screw and nut, described screw and nut are respectively arranged with three, three groups of circular holes are uniformly offered in the position of the cross section 1-2cm apart from described first nozzle, described screw is through described circular hole and fixes with described nut, and described nut is stuck on described first flat board.
7. the device of metabolite during collection rat constraint according to claim 1, it is characterized in that, described device also includes screw and nut, described screw and nut are respectively arranged with three, uniformly offering three groups of circular holes in the position of the cross section 1-2cm apart from described second nozzle, described screw is through described circular hole and fixes with described nut.
8. the device of metabolite during collection rat constraint according to claim 1, it is characterized in that, described bayonet socket holder is have inner chamber cylindric, described bayonet socket holder surface offers the first circular hole and the second circular hole, described feces collector is placed in described first circular hole, described urine collector is placed in described second circular hole, and the inner chamber of described bayonet socket holder is placed with ice cube.
9. the device of metabolite during collection rat constraint according to claim 8, it is characterized in that, described feces collector is teat glass, test tube mouth abuts described filter screen end, described urine collector includes centrifuge tube and pan, and described pan includes pan body and pan neck, and described pan body is through the second circular hole and is stuck on the second circular hole, described pan neck is inserted in described centrifuge tube, and described pan body is just to described hole clipping.
10. the device of metabolite during collection rat constraint according to claim 9, it is characterised in that described cylinder internal diameter is 4-6cm, and length is 18-20cm；
Described screen specification is 30-50 order, and length is 13-19cm, and width is 5-8cm；
The diameter of described hole clipping is 5-8cm, and the diameter of described draw-in groove is identical with the internal diameter of described cylinder；
The external diameter of described bayonet socket holder is 8-10cm, is highly 6-10cm；The diameter of described first circular hole is 1.5-2.5cm, and the diameter of described second circular hole is 4-8cm；Described test tube internal diameter is 1-2cm, is highly 8-12cm；Described centrifuge tube volume is 4-6ml, and the internal diameter of described pan body is 6-10cm.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520782102 | 2015-09-30 | ||
| CN2015207821023 | 2015-09-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205388543U true CN205388543U (en) | 2016-07-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620136043.7U Expired - Fee Related CN205388543U (en) | 2015-09-30 | 2016-02-21 | Device of metabolite during constraint of collection rat |
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| CN (1) | CN205388543U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108835026A (en) * | 2018-05-16 | 2018-11-20 | 邓国华 | A kind of new Chronic Stress Model |
-
2016
- 2016-02-21 CN CN201620136043.7U patent/CN205388543U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108835026A (en) * | 2018-05-16 | 2018-11-20 | 邓国华 | A kind of new Chronic Stress Model |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160720 Termination date: 20170221 |
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| CF01 | Termination of patent right due to non-payment of annual fee |