CN205307865U - Nozzle droplet liquid -liquid extraction device - Google Patents
Nozzle droplet liquid -liquid extraction device Download PDFInfo
- Publication number
- CN205307865U CN205307865U CN201620071526.3U CN201620071526U CN205307865U CN 205307865 U CN205307865 U CN 205307865U CN 201620071526 U CN201620071526 U CN 201620071526U CN 205307865 U CN205307865 U CN 205307865U
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- Prior art keywords
- liquid
- nozzle
- droplet
- extraction
- extraction plant
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- 238000000622 liquid--liquid extraction Methods 0.000 title claims abstract description 24
- 238000000638 solvent extraction Methods 0.000 title claims abstract description 24
- 238000000605 extraction Methods 0.000 claims abstract description 64
- 239000007788 liquid Substances 0.000 claims abstract description 58
- 238000010438 heat treatment Methods 0.000 claims abstract description 36
- 241000883990 Flabellum Species 0.000 claims abstract description 12
- 239000006185 dispersion Substances 0.000 claims abstract description 5
- 239000002245 particle Substances 0.000 claims description 4
- 239000000839 emulsion Substances 0.000 abstract description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 33
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 19
- 210000002700 urine Anatomy 0.000 description 14
- 239000000243 solution Substances 0.000 description 12
- 238000000034 method Methods 0.000 description 11
- 239000007791 liquid phase Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000000889 atomisation Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000004945 emulsification Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000005272 metallurgy Methods 0.000 description 1
- 238000002414 normal-phase solid-phase extraction Methods 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 238000005504 petroleum refining Methods 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
Abstract
The utility model discloses a nozzle droplet liquid -liquid extraction device, make up including the droplet and put (1), extraction device (2) and heating device (3), the droplet is made up and is put (1) including installing nozzle (11) on extraction device (2) for convey the extract to syringe pump (12) of nozzle (11), be used for controlling motor (13) of nozzle (11) work and install flabellum (14) that are used for dispersion extract liquid drop on nozzle (11) top, extraction device (2) are including being used for holding solution bottle (21) of sample liquid and installing that the extract conveys to export (22) of heating device (3) after solution bottle (21) one end is used for the layering, heating device (3) are including heating bottle (31) and install heater (32) in heating bottle (31) bottom. The utility model discloses can effectually prevent that emulsion phenomenon from producing, realized the full automatization operation when having improved extraction efficiency.
Description
Technical field
The utility model relates to extraction plant field, is specifically related to a kind of nozzle droplet liquid liquid extraction plant.
Background technology
Liquid-liquid extraction refers to the process that after two kinds of complete insoluble or liquid phases of mixing of part contact, wherein the solute in a kind of liquid phase enters another liquid phase through physics or chemical action or redistributes in two-phase. Liquid-liquid extraction utilizes the difference of material solubleness or partition ratio in the solvent that two kinds immiscible or part mixes, solute substance is made to transfer to another solvent in a kind of solvent, it is widely used in the industry such as chemistry, metallurgy, food, is common to petroleum refining industry.
The sample pre-treatments that laboratory often uses, mainly contain liquid-liquid extraction and Solid-Phase Extraction, for during processing blood one class sample owing to containing more various materials, granule content is big, has many interfering substances simultaneously, use existing extracting process difficulty bigger, easily blocking, emulsification, extraction efficiency is low, time is long, the problem of consistence difference.
Summary of the invention
The utility model is big for blood one class sample extraction difficulty in order to overcome in prior art, easily block, emulsification, extraction efficiency is low, time is long, the problem of consistence difference, it is provided that a kind of shower nozzle atomization liquid liquid extraction plant, can effectively prevent emulsion from producing, achieve full-automatic operation what improve extraction efficiency simultaneously.
In order to realize above-mentioned purpose, the utility model provides: a kind of nozzle droplet liquid liquid extraction plant, comprises droplet gasifying device, extraction plant and heating unit. Droplet gasifying device comprises the nozzle being arranged on extraction plant, for extraction liquid being sent to the syringe pump of nozzle, the motor worked for Control Nozzle and the flabellum for dispersion extraction liquid drop being arranged on nozzle tip, nozzle is by the rotation of screw rod, extraction liquid is brought in spiral slot from nozzle entrance, screw rod high speed rotating, liquid is made to produce certain kinetic energy, when through jet exit, liquid presses helical trajectory ejection, forming tiny droplet, droplet is dispersed in sample liquid by the rotation of flabellum; Extraction plant comprises the solution bottle for holding sample liquid and is arranged on solution bottle one end for extraction liquid after layering is sent to the outlet of heating unit.
A kind of nozzle droplet liquid liquid extraction plant described in the utility model, as optimal way, screw rod has 4 road spiral-linees, and the spiral-line degree of depth is 0.2mm.
A kind of nozzle droplet liquid liquid extraction plant described in the utility model, as optimal way, heating unit comprises heating bottle and is arranged on the well heater bottom heating bottle.
The using method of a kind of nozzle droplet liquid liquid extraction plant described in the utility model, comprises the following steps:
Step one: sample liquid is put into solution bottle;
Step 2: extraction liquid is sent to nozzle by syringe pump;
Step 3: open motor, by the rotation of screw rod on nozzle, extraction liquid is carried out droplet, and extraction liquid droplet is evenly dispersed in sample liquid by flabellum;
Step 4: extraction liquid and sample liquid layering after liquid droplet to be extracted and the abundant hybrid switching of sample liquid;
Step 5: the extraction liquid after layering is taken out from extraction plant exit and is sent to heating unit;
Step 6: extraction liquid is concentrated by heating unit by heating.
The using method of a kind of nozzle droplet liquid liquid extraction plant described in the utility model, as optimal way, the particle diameter of extraction liquid droplet is 50 μm～100 μm. Tiny droplet increases the contact area of extraction liquid and sample liquid, effectively raises effect of extracting.
The using method of a kind of nozzle droplet liquid liquid extraction plant described in the utility model, as optimal way, the rotating speed that screw rod rotates is 1500-3000r/min. The rotating speed of screw rod is relevant with the viscosity of extraction liquid, and the more big required rotating speed of usual viscosity is more big.
The utility model, owing to extraction liquid is carried out droplet by nozzle, by tiny extraction liquid droplet and sample liquid hybrid switching, increases the contact area of extraction liquid and sample liquid, it is possible to effectively improve extraction efficiency, prevents the generation of emulsion; Simultaneously the retrieving arrangement of sample liquid and the continuity of atomization system can make this sampling device realize automatization continuous extraction, it is to increase extraction efficiency, reduce manipulation strength.
Accompanying drawing explanation
Fig. 1 is a kind of nozzle droplet liquid liquid extraction plant embodiment 1 front view;
Fig. 2 is a kind of nozzle droplet liquid liquid extraction plant embodiment 2 front view.
Reference numeral: 1, droplet gasifying device; 11, nozzle; 12, syringe pump; 13, motor; 14, flabellum; 2, extraction plant; 21, solution bottle; 22, export; 3, heating unit; 31, heating bottle; 32, well heater.
Embodiment
Embodiment 1
As shown in Figure 1, the utility model provides: a kind of nozzle droplet liquid liquid extraction plant, comprises droplet gasifying device 1, extraction plant 2 and heating unit 3. Droplet gasifying device 1 comprises the nozzle 11 being arranged on extraction plant 2, for extraction liquid being sent to the syringe pump 12 of nozzle 11, and the motor 13 worked for Control Nozzle 11 and the flabellum 14 for dispersion extraction liquid drop being arranged on nozzle 11 top; Nozzle 11 comprises a screw rod, screw rod has 4 road spiral-linees, the spiral-line degree of depth is 0.2mm, and nozzle 11, by the rotation of screw rod, will be brought into spiral slot from extraction liquid nozzle 11 ingress, screw rod high speed rotating, making liquid produce certain kinetic energy, when through jet exit, liquid presses helical trajectory ejection, forming tiny droplet, droplet is dispersed in sample liquid by the rotation of flabellum 14; The rotating speed of screw rod is relevant with the viscosity of extraction liquid, and the more big required rotating speed of viscosity is more big, and usual rotating speed is 1500-3000r/min. Extraction plant 2 comprises the solution bottle 21 for holding sample liquid and is arranged on solution bottle 21 one end for extraction liquid after layering is sent to the outlet 22 of heating unit 3.Heating unit 3 comprises heating bottle 31 and is arranged on the well heater 32 bottom heating bottle 31.
The using method of a kind of nozzle droplet liquid liquid extraction plant described in the utility model, comprises the following steps:
Step one: put into solution bottle 21 by containing stable urine sample liquid;
Step 2: extraction liquid ethyl acetate is sent to nozzle 11 by syringe pump 12, injection speed is 60ml/h;
Step 3: opening motor 13, by the rotation of screw rod on nozzle 11, ethyl acetate is carried out droplet, the particle diameter of droplet is 50 μm～100 μm, and is evenly dispersed in urine by flabellum 14 by ethyl acetate droplet;
Step 4: ethyl acetate and urine layering after the abundant hybrid switching of ethyl acetate droplet and urine, owing to the density of ethyl acetate is less than the density of urine, so ethyl acetate is positioned at upper strata after layering, urine is positioned at lower floor;
Step 5: the ethyl acetate after layering is exported 22 from extraction plant 2 and takes out and be sent to heating unit 3;
Step 6: ethyl acetate is concentrated by heating unit 3 by heating.
Being the urine of 5 μ g/ml containing stable concentration according to the detection of above-mentioned extracting process, after extraction terminates, by checking that the ethyl acetate solution after concentrating can draw the method provided according to the utility model, extraction efficiency can reach 89%.
Embodiment 2
As shown in Figure 2, the utility model provides: a kind of nozzle droplet liquid liquid extraction plant, comprises droplet gasifying device 1, extraction plant 2 and heating unit 3. Droplet gasifying device 1 comprises the nozzle 11 being arranged on extraction plant 2, for extraction liquid being sent to the syringe pump 12 of nozzle 11, and the motor 13 worked for Control Nozzle 11 and the flabellum 14 for dispersion extraction liquid drop being arranged on nozzle 11 top; Nozzle 11 comprises a screw rod, screw rod has 4 road spiral-linees, the spiral-line degree of depth is 0.2mm, and extraction liquid, by the rotation of screw rod, is brought into spiral slot from nozzle 11 ingress by nozzle 11, screw rod high speed rotating, making liquid produce certain kinetic energy, when exporting through nozzle 11, liquid presses helical trajectory ejection, forming tiny droplet, droplet is dispersed in sample liquid by the rotation of flabellum 14; The rotating speed of screw rod is relevant with the viscosity of extraction liquid, and the more big required rotating speed of viscosity is more big, and usual rotating speed is 1500-3000r/min. Extraction plant 2 comprises the solution bottle 21 for holding sample liquid and is arranged on solution bottle 21 one end for extraction liquid after layering is sent to the outlet 22 of heating unit 3. Heating unit 3 comprises heating bottle 31 and is arranged on the well heater 32 bottom heating bottle 31.
The using method of a kind of nozzle droplet liquid liquid extraction plant described in the utility model, comprises the following steps:
Step one: put into solution bottle 21 by containing stable urine sample liquid;
Step 2: extraction liquid methylene dichloride is sent to nozzle 11 by syringe pump 12, injection speed is 60ml/h;
Step 3: opening motor 13, by the rotation of screw rod on nozzle 11, methylene dichloride is carried out droplet, the particle diameter of droplet is 50 μm～100 μm, and is evenly dispersed in urine by flabellum 14 by methylene dichloride droplet;
Step 4: methylene dichloride and urine layering after the abundant hybrid switching of ethyl acetate droplet and urine, owing to the density of methylene dichloride is greater than the density of urine, so urine is positioned at upper strata after layering, methylene dichloride is positioned at lower floor;
Step 5: the methylene dichloride after layering is exported 22 from extraction plant 2 and takes out and be sent to heating unit 3;
Step 6: methylene dichloride is concentrated by heating unit 3 by heating.
Being the urine of 5 μ g/ml containing stable concentration according to the detection of above-mentioned extracting process, after extraction terminates, by checking that the dichloromethane solution after concentrating can draw the method provided according to the utility model, extraction efficiency can reach 88%.
More than illustrate the utility model just illustrating property; but not restrictive, those of ordinary skill in the art understand, when not departing from the spirit and scope that claim limits; any amendment, change or the equivalence that can make, all will fall within protection domain of the present utility model.
Claims (4)
1. a nozzle droplet liquid liquid extraction plant, comprise droplet gasifying device (1), extraction plant (2) and heating unit (3), it is characterized in that: described droplet gasifying device (1) comprises the nozzle (11) being arranged on described extraction plant (2), for extraction liquid being sent to the syringe pump (12) of described nozzle (11), for controlling the motor (13) that described nozzle (11) works and the flabellum for dispersion extraction liquid drop (14) being arranged on described nozzle (11) top; Described extraction plant (2) comprises the solution bottle (21) for holding sample liquid and is arranged on the outlet (22) that described solution bottle (21) one end is used for being sent to extraction liquid after layering described heating unit (3).
2. a kind of nozzle droplet liquid liquid extraction plant according to claim 1, it is characterised in that, described nozzle (11) comprises a screw rod, and described screw rod has 4 road spiral-linees, and the spiral-line degree of depth is 0.2mm.
3. a kind of nozzle droplet liquid liquid extraction plant according to claim 1, it is characterized in that, described heating unit (3) comprises heating bottle (31) and is arranged on the well heater (32) of described heating bottle (31) bottom.
4. a kind of nozzle droplet liquid liquid extraction plant according to claims 1 to 3 any one, it is characterised in that, the particle diameter of described extraction liquid droplet is 50 μm～100 μm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620071526.3U CN205307865U (en) | 2016-01-25 | 2016-01-25 | Nozzle droplet liquid -liquid extraction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620071526.3U CN205307865U (en) | 2016-01-25 | 2016-01-25 | Nozzle droplet liquid -liquid extraction device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205307865U true CN205307865U (en) | 2016-06-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620071526.3U Expired - Fee Related CN205307865U (en) | 2016-01-25 | 2016-01-25 | Nozzle droplet liquid -liquid extraction device |
Country Status (1)
| Country | Link |
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| CN (1) | CN205307865U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108303300A (en) * | 2018-02-12 | 2018-07-20 | 吉林省兴科利民科技开发有限公司 | Full-automatic liquid-liquid sample treatment instrument |
| CN109224512A (en) * | 2018-09-17 | 2019-01-18 | 沈阳化工大学 | A kind of shock extraction equipment and its extracting process |
| CN111405933A (en) * | 2018-08-21 | 2020-07-10 | 株式会社Lg化学 | Solid phase extraction method using micro device |
-
2016
- 2016-01-25 CN CN201620071526.3U patent/CN205307865U/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108303300A (en) * | 2018-02-12 | 2018-07-20 | 吉林省兴科利民科技开发有限公司 | Full-automatic liquid-liquid sample treatment instrument |
| CN111405933A (en) * | 2018-08-21 | 2020-07-10 | 株式会社Lg化学 | Solid phase extraction method using micro device |
| CN111405933B (en) * | 2018-08-21 | 2021-12-07 | 株式会社Lg化学 | Solid phase extraction method using micro device |
| US11260319B2 (en) | 2018-08-21 | 2022-03-01 | Lg Chem, Ltd. | Solid phase extraction method using micro device |
| CN109224512A (en) * | 2018-09-17 | 2019-01-18 | 沈阳化工大学 | A kind of shock extraction equipment and its extracting process |
| CN109224512B (en) * | 2018-09-17 | 2024-03-22 | 沈阳化工大学 | Impact extraction device and extraction method thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160615 |