CN205280673U - Efficient liquid chromatograph - Google Patents
Efficient liquid chromatograph Download PDFInfo
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- CN205280673U CN205280673U CN201620012185.2U CN201620012185U CN205280673U CN 205280673 U CN205280673 U CN 205280673U CN 201620012185 U CN201620012185 U CN 201620012185U CN 205280673 U CN205280673 U CN 205280673U
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- reservoir
- liquid chromatograph
- liquid outlet
- high performance
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Abstract
The utility model discloses an efficient liquid chromatograph, which comprises a liquid reservoir, the reservoir corresponds the order with blender, high -pressure pump, injector, chromatographic column, detector and record appearance in proper order and communicates be equipped with precision filter on the inlet pipe of reservoir be equipped with the thermostat between injector and the chromatographic column correspond the intercommunication circulating pipe on the output tube of detector, the circulating pipe corresponds the intercommunication with the diverter valve, the diverter valve sets up on the pipeline between blender and high -pressure pump. The utility model relates to an efficient liquid chromatograph's simple structure, easy operation are equipped with precision filter on the inlet pipe of reservoir, can carry out furthest's filtration to the flowing phase that gets into the reservoir through precision filter, prevent that impurity wherein from causing the influence to the testing result, improves the utility model discloses a detect the precision.
Description
Technical field
The utility model relates to high precision test instrument field, especially a kind of high performance liquid chromatograph.
Background technology
Liquid chromatograph is the difference utilizing mixture partition ratio between liquid-solid or immiscible two kinds of liquid, is first separated by mixture, then the instrument of Analysis and Identification. Liquid chromatograph is liquid or solid according to stationary phase, is divided into again liquid-liquid chromatograph (LLC) and liquid-solid chromatogram (LSC). Modern liquid chromatography instrument is made up of parts such as high pressure pump, sampling system, temperature controlling system, chromatographic column, detector, signal recording systems. Compare with classical liquid column chromatography device, there is the features such as efficient, quick, sensitive. High performance liquid chromatography (HighPerformanceLiquidChromatography HPLC) is also known as " high pressure liquid chromatography ", " high-speed liquid chromatography ", " high separation liquid chromatography ", " column chromatography in modern age " etc. High performance liquid chromatography is a chromatographic important branch, take liquid as moving phase, adopt high pressure transfusion system, enter the chromatographic column of stationary phase is housed by moving phase pumps such as the mixed solvent of the single solvent or different ratios with opposed polarity, damping fluids, in post each composition separated after, enter detector to detect, thus realize the analysis to sample. The method has become separate analytical technique important in the subject fields such as chemistry, medical science, industry, agronomy, commodity inspection and method inspection.
High performance liquid chromatography has the feature of " four high wide ":
1. high pressure: moving phase is liquid, when flowing through chromatographic column, the resistance being subject to is relatively big, in order to pass through rapidly chromatographic column, it is necessary to added high pressure by carrier fluid.
2. at a high speed: analysis speed is fast, carrier fluid flow velocity is fast, and more classical liquid chromatography method speed is faster, usually analyzing a sample at 15��30 minutes, some sample even can complete in 5 minutes, is generally less than 1 hour.
3. efficient: separation efficiency height. Stationary phase and moving phase can be selected to reach optimal separation effect, more high than the separation efficiency of industrial distillation column and gas-chromatography times.
4. highly sensitive: UV-detector can reach 0.01ng, sample size is in �� L number level.
5. applied range: organic compound the usable highly effective liquid-phase chromatographic analysis, particularly high boiling point of more than 70 percent, the compartment analysis of macromole, by force polarity, poor heat stability compound, it is shown that advantage.
In addition high performance liquid chromatography also has that chromatographic column can Reusability, sample be destroyed, the easy advantage such as recovery, but also has shortcoming, has his own strong points, mutually supplement compared with gas-chromatography. The shortcoming of high performance liquid chromatography has " extra-column effect ". From entering sample to detector, in any dead space (sampler, column joint, pipe connecting and detection cell etc.) except pillar, if the flow pattern of moving phase changes, any diffusion and the delay of separated material all can cause widening of chromatographic peak significantly, and column efficiency reduces. The sensitivity of high performance liquid chromatography detector is not as good as gas-chromatography.
Practical novel content
For the defect in existing technology, it is provided that a kind of high performance liquid chromatograph.
The utility model is realized by following proposal:
A kind of high performance liquid chromatograph, comprise reservoir, described reservoir is sequential communication corresponding to mixing tank, high-pressure pump, sampler, chromatographic column, detector and registering instrument successively, the feed-pipe of described reservoir is provided with accurate filter, it is provided with thermostatted between described sampler and chromatographic column, corresponding communication loop pipe on the output tube of described detector, the connection corresponding to switching valve of described circulation tube, described switching valve is arranged on the pipeline between mixing tank and high-pressure pump;
Described accurate filter is provided with fluid inlet and liquid outlet, and the connection corresponding to feed-pipe of described liquid outlet, is provided with supporting plate layer in described accurate filter, and the top correspondence at described supporting plate layer is provided with multilayer filter core;
Described multilayer filter core comprise under distribute successively fine sand layer, pearl rock stratum, quartz sand layer, active carbon layer.
Described fluid inlet is provided with liquid inlet electromagnetic valve.
Described liquid outlet is provided with liquid outlet electromagnetic valve.
The beneficial effects of the utility model are:
1. the structure of a kind of high performance liquid chromatograph of the utility model is simple, simple to operate, the feed-pipe of reservoir is provided with accurate filter, the moving phase entering reservoir can be filtered to greatest extent by accurate filter, prevent impurity wherein from detected result being impacted, it is to increase accuracy of detection of the present utility model.
2. a kind of high performance liquid chromatograph of the utility model is provided with supporting plate layer in accurate filter, top correspondence at described supporting plate layer is provided with multilayer filter core, the top that multilayer filter core is arranged on supporting plate layer can facilitate and follow-up accurate filter of the present utility model be carried out care and maintenance, is provided with four metafiltration core layers from coarse to fine and can improve the filter effect to moving phase;
3. a kind of high performance liquid chromatograph of the utility model is provided with liquid inlet electromagnetic valve on described fluid inlet, is provided with liquid outlet electromagnetic valve, can carry out automated operation easily by liquid inlet electromagnetic valve and liquid outlet electromagnetic valve on described liquid outlet.
Accompanying drawing explanation
Fig. 1 is a kind of high performance liquid chromatograph structural representation of the utility model;
In figure: 1 is reservoir, 2 is mixing tank, and 3 is high-pressure pump, and 4 is sampler, 5 is chromatographic column, and 6 is detector, and 7 is registering instrument, and 8 is feed-pipe, 9 is accurate filter, and 91 is fluid inlet, and 92 is liquid outlet, and 93 is liquid inlet electromagnetic valve, 94 is liquid outlet electromagnetic valve, and 95 is supporting plate layer, and 96 is fine sand layer, 97 is pearl rock stratum, and 98 is quartz sand layer, and 99 is active carbon layer, 10 is thermostatted, and 11 is circulation tube, and 12 is switching valve.
Embodiment
Below in conjunction with Fig. 1, the utility model preferred embodiment is illustrated further:
A kind of high performance liquid chromatograph, comprise reservoir 1, described reservoir 1 is sequential communication corresponding to mixing tank 2, high-pressure pump 3, sampler 4, chromatographic column 5, detector 6 and registering instrument 7 successively, the feed-pipe 8 of described reservoir 1 is provided with accurate filter 9, it is provided with thermostatted 10 between described sampler 4 and chromatographic column 5, corresponding communication loop pipe 11 on the output tube of described detector 6, the connection corresponding to switching valve 12 of described circulation tube 11, described switching valve 12 is arranged on the pipeline between mixing tank 2 and high-pressure pump 3; 1. the structure of a kind of high performance liquid chromatograph of the utility model is simple, simple to operate, the feed-pipe of reservoir is provided with accurate filter, the moving phase entering reservoir can be filtered to greatest extent by accurate filter, prevent impurity wherein from detected result being impacted, it is to increase accuracy of detection of the present utility model.
Described accurate filter 9 is provided with fluid inlet 91 and liquid outlet 92, and the connection corresponding to feed-pipe 8 of described liquid outlet 92, is provided with supporting plate layer 95 in described accurate filter 9, and the top correspondence at described supporting plate layer 95 is provided with multilayer filter core; Described multilayer filter core comprise under distribute successively fine sand layer 96, pearl rock stratum 97, quartz sand layer 98, active carbon layer 99. A kind of high performance liquid chromatograph of the utility model is provided with supporting plate layer in accurate filter, top correspondence at described supporting plate layer is provided with multilayer filter core, the top that multilayer filter core is arranged on supporting plate layer can facilitate and follow-up accurate filter of the present utility model be carried out care and maintenance, is provided with four metafiltration core layers from coarse to fine and can improve the filter effect to moving phase;
Described fluid inlet 91 is provided with liquid inlet electromagnetic valve 93. Described liquid outlet 92 is provided with liquid outlet electromagnetic valve 94. A kind of high performance liquid chromatograph of the utility model is provided with liquid inlet electromagnetic valve on described fluid inlet, is provided with liquid outlet electromagnetic valve, can carry out automated operation easily by liquid inlet electromagnetic valve and liquid outlet electromagnetic valve on described liquid outlet.
Although the technical solution of the utility model having been done comparatively detailed elaboration and having enumerated; it is to be understood that; to those skilled in the art; above-described embodiment is made amendment or adopts equivalent replacement scheme; this is apparent to those skilled in the art; these modifications or improvements on the basis not deviateing the utility model spirit, all belong to the scope that the utility model is claimed.
Claims (3)
1. a high performance liquid chromatograph, comprise reservoir (1), it is characterized in that: described reservoir (1) successively with mixing tank (2), high-pressure pump (3), sampler (4), chromatographic column (5), detector (6) and the corresponding sequential communication of registering instrument (7), the feed-pipe (8) of described reservoir (1) is provided with accurate filter (9), thermostatted (10) it is provided with between described sampler (4) and chromatographic column (5), corresponding communication loop pipe (11) on the output tube of described detector (6), described circulation tube (11) connection corresponding to switching valve (12), described switching valve (12) is arranged on the pipeline between mixing tank (2) and high-pressure pump (3),
Described accurate filter (9) is provided with fluid inlet (91) and liquid outlet (92), described liquid outlet (92) connection corresponding to feed-pipe (8), being provided with supporting plate layer (95) in described accurate filter (9), the top correspondence described supporting plate layer (95) is provided with multilayer filter core;
Described multilayer filter core comprise under distribute successively fine sand layer (96), pearl rock stratum (97), quartz sand layer (98), active carbon layer (99).
2. a kind of high performance liquid chromatograph according to claim 1, it is characterised in that: on described fluid inlet (91), it is provided with liquid inlet electromagnetic valve (93).
3. a kind of high performance liquid chromatograph according to claim 1, it is characterised in that: on described liquid outlet (92), it is provided with liquid outlet electromagnetic valve (94).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620012185.2U CN205280673U (en) | 2016-01-07 | 2016-01-07 | Efficient liquid chromatograph |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620012185.2U CN205280673U (en) | 2016-01-07 | 2016-01-07 | Efficient liquid chromatograph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205280673U true CN205280673U (en) | 2016-06-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620012185.2U Expired - Fee Related CN205280673U (en) | 2016-01-07 | 2016-01-07 | Efficient liquid chromatograph |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205280673U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110709695A (en) * | 2017-07-04 | 2020-01-17 | 株式会社岛津制作所 | Liquid feeding device and liquid chromatograph |
-
2016
- 2016-01-07 CN CN201620012185.2U patent/CN205280673U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110709695A (en) * | 2017-07-04 | 2020-01-17 | 株式会社岛津制作所 | Liquid feeding device and liquid chromatograph |
| US11143635B2 (en) | 2017-07-04 | 2021-10-12 | Shimadzu Corporation | Liquid delivery device and liquid chromatograph |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160601 Termination date: 20180107 |