CN205251573U - Endothelial function aassessment detecting system based on FMD - Google Patents
Endothelial function aassessment detecting system based on FMD Download PDFInfo
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- CN205251573U CN205251573U CN201521061628.9U CN201521061628U CN205251573U CN 205251573 U CN205251573 U CN 205251573U CN 201521061628 U CN201521061628 U CN 201521061628U CN 205251573 U CN205251573 U CN 205251573U
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Abstract
The utility model provides an endothelial function aassessment detecting system based on FMD gathers the blood volume pulsation ripples of left fingertip and right fingertip respectively through left fingertip blood volume pulsation ripples detector (81) and right fingertip blood volume pulsation ripples detector (82), pressurizes to the arteria brachialis of left hand arm or right hand arm and block its blood flow in arteria brachialis pressurization sleeve area (9), host computer (4) are pressurizeed according to the arteria brachialis and are blocked long -pending change in the left fingertip blood volume pulsation wave face in front and back and the long -pending change in right fingertip blood volume pulsation wave face, calculate endothelial function situation index, can evaluate the endothelial function comprehensively, have shortened the arteria brachialis time of blocking, lowering system manufacturing cost.
Description
Technical field
The utility model relates to field of medical, relates in particular to a kind of assessment of the function of vascular endothelium based on FMD detection system.
Background technology
Blood circulation of human body system is the systematic entirety being made up of heart and blood vessel, blood vessel endothelium system is one of Functional tissue of human body maximum, the complete and function of vascular endothelium of blood vessel endothelium normally for smooth and blood flow unimpeded significant that maintains vascular wall. Normal blood vessel endothelium mainly has barrier function, acceptance and transmission of information function and secreting function. No matter clinical research shows angiocardiopathy or peripheral artery disease, and both common traits are blood vessel endothelium dysfunctions. As palsy, myocardial infarction, ischemic nephropathy and Charcot's syndrome etc. have common pathologic basis, i.e. blood vessel endothelium dysfunction.
The earlier detection of angiocardiopathy group of people at high risk being carried out to function of vascular endothelium, notes abnormalities, and takes some countermeasures in early days, and prevention and retarding cardiovascular diseases are developed, and has very important meaning. At present the detection of function of vascular endothelium is adopted to flow-mediated (FlowMediatedDilation, FMD) method conventionally, claim again ultrasonic FMD method. Arteria brachialis is not only the position of Measure blood pressure, is also important " window " that detects systemic arterial function. The common step of flow-mediated method is: first arteria brachialis position pressurization to arteria brachialis is blocked 5～10 minutes; Rapid release pressure afterwards, make high speed blood flow impact big or small Wall of Artery, high speed blood flow promotes the release of vascular relaxing factor (NO) to the shear force effect of vascular wall, and utilize accurate color ultrasound to observe the degrees of expansion of whole process medium vessels, and evaluate function of vascular endothelium according to the degrees of expansion of blood vessel (rate of change of blood vessel diameter). Ultrasonic FMD method is to evaluate the most frequently used non-invasive methods of function of vascular endothelium, and it is the golden index of evaluating function of vascular endothelium that its testing result is construed to. But there is the shortcoming that is difficult to overcome in ultrasonic FMD method, mainly to need well-trained operator, dynamics, external environment and oneself state etc. that pressurization cuff tangent plane and probe are pressed all can exert an influence to result, and the cost of device therefor is very high, the flow-mediated parameter detecting is the rate of change of arteria brachialis blood vessel diameter, its susceptibility lower (being no more than 71%).
For this reason, prior art has proposed again to measure the PAT method (PeripheralArteryTonometry) of the rate of change of finger tip tension force pulse wave amplitudes before and after blocking-up brachial artery flow on the basis of FMD method, and when this rate of change is critical point higher than 1.68 time, endothelial function is normal. With the comparison of ultrasonic FMD method, its advantage is that simple and efficient to handle, susceptibility brings up to 82%, can be used for early screening diagnosis function of vascular endothelium. But PAT method still has weak point, mainly in the time of information gathering, blocking-up arteria brachialis overlong time causes experimenter to be difficult for accepting, and critical point only relies on the rate of change of finger tip tension force pulse wave amplitude to obtain, omit other active ingredients of pulse wave, therefore can't more fully evaluate function of vascular endothelium.
Utility model content
The purpose of this utility model is to provide a kind of function of vascular endothelium based on FMD assessment detection system, can comprehensive assessment function of vascular endothelium, shorten arteria brachialis Xining, and reduce system production cost.
For achieving the above object, the utility model provides a kind of assessment of the function of vascular endothelium based on FMD detection system, comprising: main frame, the display being connected with described main frame, the left finger tip blood volume pulsation wave detector being connected with described main frame, right finger tip blood volume pulsation wave detector and arteria brachialis pressurization cuff;
Described left finger tip blood volume pulsation wave detector and right finger tip blood volume pulsation wave detector are respectively used to gather the blood volume pulsation wave of left finger tip and right finger tip;
Described display is used for showing left finger tip blood volume pulsation wave and right finger tip blood volume pulsation wave and shows testing process and result;
Described arteria brachialis pressurization cuff is for its blood flow of blocking-up that the arteria brachialis of left hand arm or right arm is pressurizeed;
Described main frame, for according to the variation of left finger tip blood volume pulsation wave area and the variation of right finger tip blood volume pulsation wave area before and after arteria brachialis pressurization blocking-up, calculates function of vascular endothelium situation index.
Described main frame comprises main frame slave case and the mainframe box being connected with main frame slave case;
Described main frame slave case is electrically connected display, keyboard and mouse;
Described main frame slave case is provided with several indicator lamps, line voltmeter and several button;
Described mainframe box is provided with function socket and cuff socket, described mainframe box, by this function socket and described left finger tip blood volume pulsation wave detector and the electric connection of right finger tip blood volume pulsation wave detector, is connected by this cuff socket and described arteria brachialis pressurization cuff.
The indicator lamp driver module that is provided with the second microprocessor in described main frame, is electrically connected with the arteria brachialis pressure processing module of described the second microprocessor electric connection and with described the second microprocessor;
Described function socket and the second microprocessor are electrically connected;
Described arteria brachialis pressure processing module is connected with described arteria brachialis pressurization cuff by cuff socket;
Described indicator lamp driver module and described several indicator lamp are electrically connected;
Described the second microprocessor is also electrically connected industrial computer, and described industrial computer is electrically connected display and USB interface;
Described the second microprocessor and industrial computer are all electrically connected lithium battery, and described lithium battery electrically connects power source protective module.
Described left finger tip blood volume pulsation wave detector and right finger tip blood volume pulsation wave detector include: finger tip pulse transducer, rc low pass filter with described finger tip pulse transducer electric connection, the follower being electrically connected with described rc low pass filter, preamplifier with described follower electric connection, active band-pass filter with described preamplifier electric connection, digital-control amplifier with described active band-pass filter electric connection, the first impedance with described digital-control amplifier electric connection, the second impedance in parallel with described the first impedance and be electrically connected with described digital-control amplifier, reference power supply with described the first and second impedances electric connections, and the first microprocessor being electrically connected with described digital-control amplifier.
The beneficial effects of the utility model: the utility model provides a kind of assessment of the function of vascular endothelium based on FMD detection system, gather respectively the blood volume pulsation wave of left finger tip and right finger tip by left finger tip blood volume pulsation wave detector and right finger tip blood volume pulsation wave detector, arteria brachialis pressurization cuff pressurizes and blocks its blood flow the arteria brachialis of left hand arm or right arm, described main frame is according to the variation of left finger tip blood volume pulsation wave area and the variation of right finger tip blood volume pulsation wave area before and after arteria brachialis pressurization blocking-up, calculate function of vascular endothelium situation index, can comprehensive assessment function of vascular endothelium, shorten arteria brachialis Xining, reduction system production cost.
In order further to understand feature of the present utility model and technology contents, refer to following about detailed description of the present utility model and accompanying drawing, but accompanying drawing only provide with reference to and explanation use, be not used for the utility model to be limited.
Brief description of the drawings
Below in conjunction with accompanying drawing, by detailed description of the invention of the present utility model is described in detail, will make the technical solution of the utility model and other beneficial effect apparent.
In accompanying drawing,
Fig. 1 is the structural representation of the assessment of the function of vascular endothelium based on FMD detection system of the present utility model;
Fig. 2 is the system module figure of the assessment of the function of vascular endothelium based on FMD detection system of the present utility model;
Fig. 3 is the schematic diagram of finger tip blood volume pulsation wave detector in the assessment of the function of vascular endothelium based on FMD detection system of the present utility model;
Fig. 4 is the schematic diagram of the main frame in the assessment of the function of vascular endothelium based on FMD detection system of the present utility model;
Fig. 5 is the schematic diagram of the power supply in the assessment of the function of vascular endothelium based on FMD detection system of the present utility model;
Fig. 6 is the workflow diagram of the function of vascular endothelium assessment detection system of the utility model based on FMD.
Detailed description of the invention
Technological means and the effect thereof taked for further setting forth the utility model, be described in detail below in conjunction with preferred embodiment of the present utility model and accompanying drawing thereof.
Refer to Fig. 1 and Fig. 2, the utility model provides a kind of assessment of the function of vascular endothelium based on FMD detection system, comprising: main frame 4, the display 1 being connected with described main frame 4, the left finger tip blood volume pulsation wave detector 81 being connected with described main frame 4, right finger tip blood volume pulsation wave detector 82 and arteria brachialis pressurization cuff 9;
Described left finger tip blood volume pulsation wave detector 81 and right finger tip blood volume pulsation wave detector 82 are respectively used to gather the blood volume pulsation wave of left finger tip and right finger tip;
Described display 1 is for showing left finger tip blood volume pulsation wave and right finger tip blood volume pulsation wave and showing testing process and result;
Described arteria brachialis pressurization cuff 9 is for its blood flow of blocking-up that the arteria brachialis of left hand arm or right arm is pressurizeed;
Described main frame 4, for according to the variation of left finger tip blood volume pulsation wave area and the variation of right finger tip blood volume pulsation wave area before and after arteria brachialis pressurization blocking-up, calculates function of vascular endothelium situation index.
Concrete, described main frame 4 comprises main frame slave case 41 and the mainframe box 42 being connected with main frame slave case 41; Described main frame slave case 41 is electrically connected display 1, keyboard 31 and mouse 32; Described main frame slave case 41 is provided with several indicator lamps 411, line voltmeter 413 and several button 412; Described mainframe box 42 is provided with function socket 422 and cuff socket 423, described mainframe box 42 is electrically connected by this function socket 422 and described left finger tip blood volume pulsation wave detector 81 and right finger tip blood volume pulsation wave detector 82, is connected with described arteria brachialis pressurization cuff 9 by this cuff socket 423.
Further, described display 1 below is provided with display bracket 2, is provided with VGA cable and power cable passage in described display bracket 2; Described display 1 is electrically connected by this VGA cable passage and main frame slave case 41, and the shift knob of described feed cable in several buttons 412 is electrically connected lithium battery 102.
Concrete, refer to Fig. 4 and Fig. 5, in described main frame 4, be provided with the second microprocessor 424, the arteria brachialis pressure processing module 425 being electrically connected with described the second microprocessor 424 and the indicator lamp driver module 426 being electrically connected with described the second microprocessor 424; Described function socket 422 and the second microprocessor 424 are electrically connected; Described arteria brachialis pressure processing module 424 is connected with described arteria brachialis pressurization cuff 9 by cuff socket 423; Described indicator lamp driver module 426 is electrically connected with described several indicator lamps 411; Described the second microprocessor 424 is also electrically connected industrial computer 100, and described industrial computer 100 is electrically connected display 1 and usb 1 01; Described the second microprocessor 424 and industrial computer 100 are all electrically connected lithium battery 102, and described lithium battery 102 is electrically connected power source protective module 103, by this lithium ion battery 102, described main frame 4, industrial computer 100 and display 1 are powered.
Concrete, refer to Fig. 3, described left finger tip blood volume pulsation wave detector 81 and right finger tip blood volume pulsation wave detector 82 include: finger tip pulse transducer 811, the rc low pass filter 812 being electrically connected with described finger tip pulse transducer 811, the follower 813 being electrically connected with described rc low pass filter 812, the preamplifier 814 being electrically connected with described follower 813, the active band-pass filter 815 being electrically connected with described preamplifier 814, the digital-control amplifier 819 being electrically connected with described active band-pass filter 815, the first impedance 817 being electrically connected with described digital-control amplifier 819, the second impedance 818 in parallel with described the first impedance 817 and be electrically connected with described digital-control amplifier 819, with described the first and second impedances 818, 817 reference power supplies 816 that are electrically connected, and the first microprocessor 820 being electrically connected with described digital-control amplifier 819. further, described active band-pass filter 815 electricity connection function sockets 422, are electrically connected main frame 4 and described left finger tip blood volume pulsation wave detector 81 and right finger tip blood volume pulsation wave detector 82. preferably, the model of described follower 813 is LT1112, and the model of described bandpass filter 815 is RC4558, and the voltage of described reference power supply 816 is 1.5V.
Further, the described function of vascular endothelium based on FMD assessment detection system also comprise the printer 5 that is electrically connected with described main frame 4, for place printer 5 chassis bracket 6, be installed on the wheel 7 of described chassis bracket 6 belows.
The utility model proposes the basic characteristic quantity F value that is changed to of a pulse waveform area that changes to cause because of CBF, and define its value and be:
F＝(Vm－VD)/(VS－VD)
Or Vm=VD+Q (VS-VD)
In formula,
Vm is mean blood flow, equals the mean value of CBF in the cardiac cycle, and f (t) is pulse wave function,For pulse waveform area, VS, VD are respectively peak value CBF and residual blood volume, and pulse waveform area is the area covering between VS and VD, and T is cardiac cycle.
Refer to Fig. 6, the course of work of the function of vascular endothelium assessment detection system of the utility model based on FMD, comprises the steps:
Step 1, provide the function of vascular endothelium based on a FMD assessment detection system, comprising: main frame 4, the display 1 being connected with described main frame 4, the left finger tip blood volume pulsation wave detector 81 being connected with described main frame 4, right finger tip blood volume pulsation wave detector 82 and the arteria brachialis cuff 9 that pressurizes;
Described left finger tip blood volume pulsation wave detector 81 and right finger tip blood volume pulsation wave detector 82 are connected to respectively to experimenter's left finger tip and right finger tip, the arteria brachialis cuff 9 that pressurizes is close to skin and is tied up in the arteria brachialis place of any side in experimenter's left and right.
Concrete, described arteria brachialis pressurization cuff 9 routinely Measure blood pressure method is tied up in the arteria brachialis place of any side of experimenter's left and right arm, and described general measure blood pressure method is the method that adopts the blood pressure measuring that comprises cuff to take blood pressure. Further, this step 1 can also comprise input experimenter's data and set up experimenter's archives.
Step 2, startup main frame 4, display 1 shows the blood volume pulsation wave of described left finger tip and right finger tip;
The blood volume pulsation wave of step 3, described left finger tip and right finger tip is stable to start to measure after showing, gathers respectively left finger tip in a fixing duration and the blood volume pulsation wave of right finger tip;
Step 4, to arteria brachialis pressurization cuff 9 constantly pressurization until after blocking-up arteria brachialis blood flow, continue pressurization one fixation pressure value, keep arteria brachialis blocking-up by the arteria brachialis blocking-up duration of setting.
Concrete, a fixation pressure value that continues pressurization is 50 millimetress of mercury.
Step 5, arteria brachialis blocking-up duration arrive, and arteria brachialis pressurization cuff 9 is decompressed to zero, starts flow-mediated process.
Concrete, described arteria brachialis blocking-up duration is 2～3 minutes, is preferably 3 minutes, than the arteria brachialis blocking-up duration of at least 5 minutes in prior art, has effectively reduced arteria brachialis blocking-up duration, is more easily accepted by experimenter.
Step 6, gather the left finger tip of fixing duration and the blood volume pulsation wave of right finger tip identical with step 3 respectively.
Concrete, the fixing duration in described step 3 and step 6 is 40s. The time period at two fixing duration places all can not be in obvious interference region.
Step 7, blood volume pulsation wave to described left finger tip and right finger tip carry out data processing, according to the variation of left finger tip blood volume pulsation wave area and the variation of right finger tip blood volume pulsation wave area before and after arteria brachialis pressurization blocking-up, calculate function of vascular endothelium situation index.
Concrete, described step 7 comprises:
Step 71, utilize Fourier formula that the blood volume pulsation wave of left finger tip and right finger tip is resolved into several harmonic components, each harmonic component has the harmonic component amplitude of a correspondence and the frequencies of harmonic components of a correspondence;
Step 72, the left finger tip in the fixing duration in left finger tip and right finger tip blood volume pulsation wave and step 6 and the blood volume pulsation wave of right finger tip in the fixing duration in selected step 3 respectively, calculate the mean value of the area of the low frequency component representative of each selected blood volume pulsation wave;
For each selected blood volume pulsation wave, the mean value calculation process of the area of the representative of its blood volume pulsation wave low frequency component is:
5 adjacent points of the frequencies of harmonic components of selection and 0.5Hz, 1.0Hz, 1.5Hz and 2.0Hz respectively, amount to 20 points, the harmonic component of these 20 some correspondences is low frequency component, obtain the amplitude of the low frequency component of these 20 some correspondences, these 20 points are all positioned at the fixing duration that this selected blood volume pulsation wave is corresponding;
Calculate the area of each low frequency component representative, formula is:
σn＝An×Δt，
Wherein, Δ t=1ms, n is more than or equal to 1 and be less than or equal to 20 positive integer, AnFor the amplitude of low frequency component corresponding to choose described in step 2 n point, σnFor the area of choose described in step 2 n the corresponding low frequency component representative of point;
The mean value that calculates the area of the low frequency component representative of this section of selected blood volume pulsation wave, formula is;
Wherein, f is the mean value of the area of the low frequency component representative of this section of blood volume pulsation wave;
Step 73, calculating function of vascular endothelium situation index, formula is:
Q＝(fb×fc)/(fa×fd)
Wherein, Q is function of vascular endothelium situation index; Fa, fc are respectively in step 3 mean value of the area of the low frequency component representative of the left finger tip that gathers and right finger tip blood volume pulsation wave; Fb, fd are respectively in step 6 mean value of the area of the low frequency component representative of the left finger tip that gathers and right finger tip blood volume pulsation wave. Further, the computing formula of above-mentioned function of vascular endothelium situation index has been eliminated the impact of the many factors such as system, nerve, breathing, autonomous or external interference, thereby obtains the actual value of endothelial function.
It is worth mentioning that, as follows to the procedure declaration of utilizing Fourier formula that the blood volume pulsation wave of left finger tip and right finger tip is resolved into several harmonic components in described step 71:
First blood volume pulsation wave is done to low pass, the logical pretreatment of active band, remove baseline drift blood volume pulsation wave bottom is evened up, utilize the wavelet transformation technique that can give prominence to low frequency component to simplify computational process;
Then, blood volume pulsation wave function f (t) is done to Fourier analysis;
Have according to the Fourier formula of periodic function:
Wherein, T is cardiac cycle,For DC component (being residual blood volume); a1cosΩt+b1Sin Ω t is fundametal compoment, ancosΩt+bnSinn Ω t is nth harmonic component, n > 1;
Further,
Finally, the computing formula of the amplitude An of nth harmonic component is:
The frequency of nth harmonic component is: n Ω/2 π.
Said process can complete by Fourier analysis program is set in main frame 4, the blood volume pulsation wave of left finger tip and right finger tip is resolved into several harmonic components by this Fourier analysis program, and set up the database of this harmonic component amplitude and frequencies of harmonic components, be kept in main frame 4;
It is worth mentioning that, can assess function of vascular endothelium by the concrete numerical value of this function of vascular endothelium situation index Q, wherein:
In the time of Q > 1.38, function of vascular endothelium is normal;
In the time of 1.10 < Q < 1.35, there is latent lesion in function of vascular endothelium;
In the time of Q < 1.05, function of vascular endothelium is badly damaged.
In addition, can further expand several functions according to the utility model, comprise: measure cardiovascular quality factor, observe state aroused in interest, qi and blood state, autonomic nerve state, observation store the many kinds of parameters such as pulse wave.
In sum, the utility model provides a kind of assessment of the function of vascular endothelium based on FMD detection system, gather respectively the blood volume pulsation wave of left finger tip and right finger tip by left finger tip blood volume pulsation wave detector and right finger tip blood volume pulsation wave detector, arteria brachialis pressurization cuff pressurizes and blocks its blood flow the arteria brachialis of left hand arm or right arm, described main frame is according to the variation of left finger tip blood volume pulsation wave area and the variation of right finger tip blood volume pulsation wave area before and after arteria brachialis pressurization blocking-up, calculate function of vascular endothelium situation index, can comprehensive assessment function of vascular endothelium, shorten arteria brachialis Xining, reduction system production cost.
The above; for the person of ordinary skill of the art; can make other various corresponding changes and distortion according to the technical solution of the utility model and technical conceive, and all these changes and distortion all should belong to the protection domain of the utility model claim.
Claims (5)
1. the assessment of the function of vascular endothelium based on a FMD detection system, it is characterized in that, comprising: main frame (4), the display (1) being connected with described main frame (4), the left finger tip blood volume pulsation wave detector (81) being connected with described main frame (4), right finger tip blood volume pulsation wave detector (82) and arteria brachialis pressurization cuff (9);
Described left finger tip blood volume pulsation wave detector (81) and right finger tip blood volume pulsation wave detector (82) are respectively used to gather the blood volume pulsation wave of left finger tip and right finger tip;
Described display (1) is for showing left finger tip blood volume pulsation wave and right finger tip blood volume pulsation wave and showing testing process and result;
Described arteria brachialis pressurization cuff (9) is for its blood flow of blocking-up that the arteria brachialis of left hand arm or right arm is pressurizeed;
Described main frame (4), for according to the variation of left finger tip blood volume pulsation wave area and the variation of right finger tip blood volume pulsation wave area before and after arteria brachialis pressurization blocking-up, calculates function of vascular endothelium situation index.
2. the assessment of the function of vascular endothelium based on FMD detection system as claimed in claim 1, it is characterized in that, described main frame (4) comprises main frame slave case (41) and the mainframe box (42) being connected with main frame slave case (41);
Described main frame slave case (41) is electrically connected display (1), keyboard (31) and mouse (32);
Described main frame slave case (41) is provided with several indicator lamps (411), line voltmeter (413) and several button (412);
Described mainframe box (42) is provided with function socket (422) and cuff socket (423), described mainframe box (42) is electrically connected by this function socket (422) and described left finger tip blood volume pulsation wave detector (81) and right finger tip blood volume pulsation wave detector (82), is connected with described arteria brachialis pressurization cuff (9) by this cuff socket (423).
3. the assessment of the function of vascular endothelium based on FMD detection system as claimed in claim 2, it is characterized in that, in described main frame (4), be provided with the second microprocessor (424), with described the second microprocessor (424) be electrically connected arteria brachialis pressure processing module (425) and with described the second microprocessor (424) be electrically connected indicator lamp driver module (426);
Described function socket (422) is electrically connected with the second microprocessor (424);
Described arteria brachialis pressure processing module (425) is connected with described arteria brachialis pressurization cuff (9) by cuff socket (423);
Described indicator lamp driver module (426) is electrically connected with described several indicator lamps (411).
4. the assessment of the function of vascular endothelium based on FMD detection system as claimed in claim 3, it is characterized in that, described the second microprocessor (424) is also electrically connected industrial computer (100), and described industrial computer (100) is electrically connected display (1) and USB interface (101);
Described the second microprocessor (424) and industrial computer (100) are all electrically connected lithium battery (102), and described lithium battery (102) is electrically connected power source protective module (103).
5. the assessment of the function of vascular endothelium based on FMD detection system as claimed in claim 3, it is characterized in that, described left finger tip blood volume pulsation wave detector (81) and right finger tip blood volume pulsation wave detector (82) include: finger tip pulse transducer (811), rc low pass filter (812) with described finger tip pulse transducer (811) electric connection, the follower (813) being electrically connected with described rc low pass filter (812), preamplifier (814) with described follower (813) electric connection, active band-pass filter (815) with described preamplifier (814) electric connection, digital-control amplifier (819) with described active band-pass filter (815) electric connection, the first impedance (817) with described digital-control amplifier (819) electric connection, in parallel with described the first impedance (817) and with described digital-control amplifier (819) be electrically connected the second impedance (818), with described the first and second impedances (817, 818) reference power supply (816) being electrically connected, and with described digital-control amplifier (819) be electrically connected first microprocessor (820).
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105433985A (en) * | 2015-12-17 | 2016-03-30 | 深圳前海圣晔尔医疗电子生物科技有限公司 | Vascular endothelial function evaluation and detection system and method based on FMD |
| CN109771245A (en) * | 2019-02-18 | 2019-05-21 | 中山大学附属第一医院 | The method and system of individual function of vascular endothelium is evaluated using external counterpulsation technology |
| CN111436997A (en) * | 2020-04-21 | 2020-07-24 | 重庆大学附属肿瘤医院 | Self-adaptive safety blocking device for noninvasive detection of vascular endothelial function |
| CN113271844A (en) * | 2019-01-09 | 2021-08-17 | 图尔库大学 | Device for measuring the function of the arterial system |
-
2015
- 2015-12-17 CN CN201521061628.9U patent/CN205251573U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105433985A (en) * | 2015-12-17 | 2016-03-30 | 深圳前海圣晔尔医疗电子生物科技有限公司 | Vascular endothelial function evaluation and detection system and method based on FMD |
| CN113271844A (en) * | 2019-01-09 | 2021-08-17 | 图尔库大学 | Device for measuring the function of the arterial system |
| CN109771245A (en) * | 2019-02-18 | 2019-05-21 | 中山大学附属第一医院 | The method and system of individual function of vascular endothelium is evaluated using external counterpulsation technology |
| CN111436997A (en) * | 2020-04-21 | 2020-07-24 | 重庆大学附属肿瘤医院 | Self-adaptive safety blocking device for noninvasive detection of vascular endothelial function |
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