CN205073543U - Beam shaper for neutron -capture therapy - Google Patents
Beam shaper for neutron -capture therapy Download PDFInfo
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- CN205073543U CN205073543U CN201520770873.0U CN201520770873U CN205073543U CN 205073543 U CN205073543 U CN 205073543U CN 201520770873 U CN201520770873 U CN 201520770873U CN 205073543 U CN205073543 U CN 205073543U
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Abstract
The utility model provides a beam shaper for neutron -capture therapy, the beam shaping body includes beam entry, target, borders on and is in in the slow fast body, the encirclement of target external reflector and beam outlet slowly invites, it can change in order to adjust the slow fast body to neutronic slowly fast ability to delay the fast body. The beam shaping body of this application neutron capture treatment only need select the slow fast body of different materials to adjust neutronic slowly fast ability according to the actual requirement of indexs such as the intrafascicular subzone of tumour correlation, neutron beam flux, just can use same platform medical equipment to treat different patients, simple structure, and the suitability is strong.
Description
Technical field
This utility model relates to a kind of beam-shaping body, particularly relates to a kind of beam-shaping body for neutron capture treatment.
Background technology
Along with the development of atomics, radiation cure one of the Main Means becoming treatment of cancer such as such as cobalt 60, linear accelerator, electron beam.But conventional photonic or electronic therapy are subject to the restriction of the physical condition of lonizing radiation own, while killing tumor cell, also can normal structures a large amount of in beam approach be damaged; In addition because tumor cell is to the difference of lonizing radiation sensitivity, traditional radiation therapy is often not good for the treatment effect of the malignant tumor (as: multirow glioblastoma multiforme (glioblastomamultiforme), melanocytoma (melanoma)) compared with tool radiation resistance.
In order to reduce the radiation injury of tumor surrounding normal tissue, the target therapy concept in chemotherapy (chemotherapy) is just applied in radiation cure; And for the tumor cell of radiation resistance, also develop actively has the radiation source of high relative biological effect (relativebiologicaleffectiveness, RBE) at present, as proton therapeutic, heavy particle therapy, neutron capture treatment etc.Wherein, neutron capture treatment is in conjunction with above-mentioned two conceptions of species, as the treatment of boron neutron capture, gathers by the specificity of boracic medicine at tumor cell, coordinates neutron beam regulation and control accurately, provides and selects than the better treatment of cancer of conventional radiation.
Boron neutron capture treatment (BoronNeutronCaptureTherapy, BNCT) be utilize boracic (
10b) medicine has the characteristic of high capture cross section to thermal neutron, by
10b (n, α)
7li neutron capture and karyokinesis reaction produce
4he and
7li two heavy burden charged particle.With reference to Fig. 1, it illustrates the schematic diagram of boron neutron capture reaction, the average energy of two charged particles is about 2.33MeV, there is High Linear transfer (LinearEnergyTransfer, LET), short range feature, the linear energy transfer of alpha-particle and range are respectively 150keV/ μm, 8 μm, and
7li heavy burden particle is then 175keV/ μm, 5 μm, the integrated range of two particle is about equivalent to a cell size, therefore the radiation injury caused for organism can be confined to cell level, when boracic drug selectivity be gathered in tumor cell, suitable neutron of arranging in pairs or groups penetrates source, just under normal tissue does not cause the prerequisite of too major injury, the object that tumor cell is killed in local can be reached.
Because the effect of boron neutron capture treatment depends on tumor cell position boracic drug level and thermal neutron quantity, therefore the binary lonizing radiation treatment of cancer (binarycancertherapy) that is otherwise known as; It can thus be appreciated that, except the exploitation of boracic medicine, in the research that the neutron improvement of penetrating source flux and quality is treated at boron neutron capture, occupy key player.
But, the beam-shaping body design of boron neutron capture treatment in prior art mostly is monoblock type fixed structure, the neutron beam quality that such beam-shaping body exports is fixed often, but in actual therapeutic process, is not machine-made to the requirement of neutron beam quality.Different patients, the kind of the position of tumor, the depth and tumor is just likely different, this will cause different to the requirement of neutron beam quality over the course for the treatment of, and in prior art, the beam-shaping body of monoblock type fixed structure cannot coordinate the practical situation of patient to treat according to quality adjust of the concrete condition of sufferer tumor to neutron beam.
Therefore, be necessary to provide a kind of new technical scheme to solve the problem in fact.
Utility model content
In order to solve the problem, an aspect of the present utility model provides a kind of beam-shaping body for neutron capture treatment, described beam-shaping body comprises beam entrance, target, be adjacent to the slow body of target, be enclosed in described reflector external slowly and beam outlet, described target and the proton beam generation nuclear reaction from the incidence of described beam entrance are to produce neutron, described slow body is by slow for the neutron produced from described target, the neutron departed from leads back to described slow body to improve epithermal neutron intensity of beam by described reflector, described slow body can be changed to adjust the slow ability of slow body to neutron.
Further, described slow body comprises the basilar part being positioned at target rear and the school extension arranged with basilar part split, and described school extension can be changed separately to adjust the slow ability of slow body to neutron.
Further, described basilar part is adjacent to target rear and fixes with target, and described school extension is installed on the rear of basilar part and is adjacent to basilar part.
Further, described school extension at least comprises the first school extension and the second school extension, described first school extension is installed on basilar part rear and is adjacent to basilar part, second school extension is installed on the first school extension rear and is adjacent to the first school extension, and described first school extension and the second school extension can be changed separately.
Further, the corresponding school extension of described reflector offers the guide groove extending to basilar part rear, and described guide groove is provided with slide rail, and described school extension is installed on and moves to basilar part rear by slide rail after in guide groove and be adjacent to basilar part; Described guide groove at least comprise corresponding with the first school extension the first guide groove and with the second school extension relative to the second guide groove; When described first school extension only material identical with the physical dimension of the second school extension is different, the first school extension and the second school extension can be arranged in the first guide groove or the second guide groove respectively; When the first school extension and material different with the physical dimension of the second school extension is also different, described first school extension is installed in the first guide groove, and described second school extension is installed in the second guide groove.
Further, reflector also comprises to be located at outside school extension two and the supplementary reflector be installed in guide groove, when school extension to be installed on the rear of basilar part by slide rail, supplement reflector and the reflector be enclosed in outside basilar part reflects the neutron of scattering jointly.
Further, described reflector is provided with rotating shaft, and described rotating shaft is provided with and is positioned at basilar part rear and can the rotating disk that rotates of opposed substrate portion, and described school extension is installed on after in rotating disk and is adjacent to basilar part with dial turning motion to basilar part rear; Described rotating disk at least comprises first rotating disk corresponding with the first school extension and second rotating disk corresponding with the second school extension; When described first school extension only material identical with the physical dimension of the second school extension is different, the first school extension and the second school extension can be arranged in the first rotating disk or the second rotating disk respectively; When the first school extension and material different with the physical dimension of the second school extension is also different, described first school extension is installed in the first rotating disk, and described second school extension is installed in the second rotating disk.
Further, reflector also comprises the supplementary reflector being located at school extension periphery, when school extension around rotating shaft rotate be installed on basilar part rear time, supplement reflector and the reflector be enclosed in outside basilar part and jointly the neutron of scattering reflected.
Further, the material of described basilar part, the first school extension and described second school extension all can by Al, Pb, Ti, Bi, C, D
2o, AlF
3, Fluental
tM, CaF
2, Li
2cO
3, MgF
2and Al
2o
3in any one or a few make.
Further, described reflector is made up of at least one in Pb or Ni, and the material of described supplementary reflector is identical with the material of reflector.
Compared with prior art, the application has following beneficial effect: slow body is designed to basilar part and school extension by the beam-shaping body that the application is used for neutron capture treatment, school extension is set to two parts that can change, in actual therapeutic process, the school extension that the concrete state of an illness (depth of patient tumors) in conjunction with patient chooses different materials is changed, thus make slow body carry out slowly to neutron beam, thus obtain the neutron beam quality of applicable patient actual needs over the course for the treatment of, structure is simple, uses flexibly.
Accompanying drawing explanation
Fig. 1 is boron neutron capture reaction schematic diagram;
Fig. 2 is the structural representation of the beam-shaping body that the application treats for neutron capture;
Fig. 3 is the structural representation using guide groove to install school extension in the application's embodiment one;
Fig. 4 is the structural representation using rotating disk to install school extension in the application's embodiment two.
Detailed description of the invention
Neutron capture treatment increases gradually as a kind of means application in recent years of effective Therapeutic cancer, wherein common with the treatment of boron neutron capture, and the neutron of supply boron neutron capture treatment can by nuclear reactor or accelerator supply.The embodiment of the application is treated for accelerator boron neutron capture, the basic module of accelerator boron neutron capture treatment generally includes accelerator, target and hot removal system for accelerating charged particle (as proton, deuteron etc.) and beam-shaping body, wherein accelerating charged particles and metal targets effect produce neutron, the characteristic such as materialization according to required neutron yield rate and energy, available accelerating charged particles energy and size of current, metal targets selects suitable nuclear reaction, and the nuclear reaction often come into question has
7li (p, n)
7be and
9be (p, n)
9b, these two kinds of reactions are all the endothermic reaction.The energy threshold of two kinds of nuclear reactions is respectively 1.881MeV and 2.055MeV, desirable neutron source due to the treatment of boron neutron capture is the epithermal neutron of keV energy grade, if use the proton bombardment lithium metal target of energy only a little higher than threshold values in theory, the neutron of relative mental retardation can be produced, slow process that must be not too many just can be used for clinical, but the proton-effect cross section of lithium metal (Li) and beryllium metal (Be) two kinds of targets and threshold values energy is not high, for producing enough large neutron flux, the proton of higher-energy is usually selected to carry out initiated core reaction.
Desirable target should possess high neutron yield rate, generation neutron energy distribution close to epithermal neutron energy district, without wearing by force too much that radiation produces, safety is cheaply easy to operation and the characteristic such as high temperature resistant, but in fact also cannot find the nuclear reaction meeting all requirements, in the embodiment of the application, adopt the metal target of lithium.But well known to those skilled in the art, the material of target also can be made up of other metal materials except the above-mentioned metal material talked about.
Requirement for hot removal system is then different according to the nuclear reaction selected, as
7li (p, n)
7be because of the fusing point of metal targets (lithium metal) and thermal conductivity coefficient poor, to the requirement of hot removal system just comparatively
9be (p, n)
9b is high.Adopt in the embodiment of the application
7li (p, n)
7the nuclear reaction of Be.
In addition, in use son is caught in treatment technology actual therapeutic process, the concrete condition of different patient tumors (kind of the position of tumor, the depth and tumor) may be different, therefore may be different from the specific requirement (the concrete scope of beam neutron energy range, neutron beam the flux even front tropism etc. of neutron beam) of the neutron beam quality produced after target generation nuclear reaction to proton.In order to make neutron capture treatment technology more accurately apply in the actual therapeutic process of tumor patient more flexibly, even apply in a greater variety of oncotherapy, the application proposes to improve to the beam-shaping body for the treatment of for neutron capture.As one preferably, be improvement for the beam-shaping body for the treatment of for accelerator boron neutron capture.
Fig. 2 to Fig. 4 is the beam-shaping body 10 for neutron capture treatment in the application, this firing rate shaping body 10 comprise beam entrance 11, target 12, be adjacent to target 12 slow body 13, be enclosed in reflector 14 outside slow body 13 and beam outlet 17.Proton beam is accelerated by accelerator by the treatment of accelerator boron neutron capture, and proton beam accelerates to the energy being enough to overcome target atom nuclear force, occurs with target 12
7li (p, n)
7be nuclear reaction is to produce neutron (with reference to Fig. 1), and the neutron of generation slows down through slow body 13, and the neutron of scattering is reflected back on beam axis by reflector 14 and exports 17 injections from beam again.
The making material of slow body 13 can have multiple, and the intrafascicular subzone of material correlation of slow body 13, neutron beam flux even before neutron beam these indexs of tropism all have a great impact, therefore slow body 13 is arranged to change formula by the application, same armarium cannot be used to carry out the situation of neutron capture treatment to solve different tumor presence (comprising the position depth, type).
Slow body 13 comprises basilar part 131 and school extension 132, and basilar part 131 and school extension 132 are split-type structural.So-called split-type structural refers to, basilar part 131 is positioned at target 12 rear, and school extension 132 is installed on basilar part 131 rear.Basilar part 131 can be set to changeable type, also can be set to fixed.When basilar part 131 is changeable type, can change respectively basilar part 131 and school extension 132; When basilar part 131 is fixed, only school extension 132 is changed.Certainly, also basilar part 131 and school extension 132 can be arranged to monoblock type, for different tumor presence, the slow ability changing slow body 13 be changed to whole slow body 13.
In the present embodiment, basilar part 131 and the school extension 132 of employing are split-type design, and basilar part 131 is fixed.The basilar part 131 of slow body 13 be arranged on the rear of target 12 and fix with target 12 is adjacent, school extension 132 is arranged on the rear of basilar part 131 and is adjacent to basilar part 131 (school extension 132 can not be adjacent to basilar part 131 and make to leave gap between basilar part 131 and school extension 132 in other embodiments).In the present embodiment, school extension 132 at least comprises the first school extension 133 and the second school extension 134.First school extension 133 is adjacent to basilar part 131 rear, and the second school extension 134 is adjacent to the first school extension 133 rear, so makes school extension 132 form the stacked of two structures, and the first school extension 133 and the second school extension 134 can be changed separately respectively.It is to be noted, because the material making slow body 13 has multiple, school extension 132 can be arranged to the stacked of two or more (three, four, five or more) multiple structure, more fine to change the slow ability of slow body, realize the more accurate demand of neutron beam quality, thus improve the therapeutic effect for different tumor.
How to realize under lower mask body introduction changing the school extension 132 of slow body 13.
It is please the structural representation of the application's embodiment one referring again to Fig. 3, Fig. 3.Reflector 14 is offered guide groove 141, is provided with slide rail 142 in guide groove 141, school extension 13 is installed on after in guide groove 141 with basilar part 132 adjacent fixing to basilar part 132 rear with the sliding motion of slide rail 142.Guide groove 141 at least comprises first guide groove 143 corresponding with the first school extension 133 and second guide groove 144 corresponding with the second school extension 134.When the overall structure of slow body 13 is cylinder, when first school extension 133 is identical with the physical dimension of the second school extension 134, as long as the neutron beam quality requirements obtained as required selects the first school extension 133 of different materials and the second school extension 134 to be arranged in the first guide groove 143 or the second guide groove 144.That is, in this case, because the first school extension 133 is identical with the physical dimension of the second school extension 134, as long as require so the material being arranged on the school extension 132 in the first guide groove 143 and the second guide groove 144 can make the neutron beam quality obtained after slow body 13 can reach expection, actually or and neutralize the first school extension 133 second school extension 134 not restriction of installing in the second guide groove 144 to the first guide groove 143.When the overall structure of slow body 13 is cylinders, or cone or be the combination of cylinder and cone, and the first school extension 133 different with the physical dimension of the second school extension 134 time, the neutron beam quality requirements obtained as required selects the first school extension 133 and the second school extension 134 of different materials, first school extension 133 can only correspondence be installed in the first guide groove 143, and the second school extension 134 also can only correspondence be installed in the second guide groove 144.
Reflector 14 also comprises is located at school extension 131 liang of outsides and the supplementary reflector 145 be installed in guide groove 141.Supplementing after reflector 145 can make an entirety with school extension 131 is installed in guide groove 141, also can be installed on respectively in guide groove 141 separately after school extension 131 is installed in guide groove 141.When school extension 131 is installed on the rear of basilar part 132 by slide rail 142, supplement reflector 145 jointly to reflect the neutron of scattering with the reflector 14 be enclosed in outside basilar part 131, to make the neutron of scattering be reflected back toward on neutron beam main shaft, to improve the intensity of beam of epithermal neutron.
It is please the structural representation of the application's embodiment two referring again to Fig. 4, Fig. 4.In embodiment two, the parts identical with embodiment one adopt the figure notation same with embodiment one.Reflector 14 is arranged one with the rotating shaft 15 of the centerline parallel of the basilar part 131 of slow body 13, rotating shaft 15 is provided with and is positioned at basilar part 131 rear and can the rotating disk 146 that rotates of opposed substrate portion 131.To rotate to basilar part 131 rear and adjacent fixing with basilar part 131 around rotating shaft 15 with rotating disk after school extension 132 is installed on rotating disk 146.Rotating disk 146 at least comprises first rotating disk 147 corresponding with the first school extension 133 and second rotating disk 148 corresponding with the second school extension 144.When the overall structure of slow body 13 is cylinder, when first school extension 133 is identical with the physical dimension of the second school extension 134, as long as the neutron beam quality requirements obtained as required selects the first school extension 133 of different materials and the second school extension 134 to be arranged in the first rotating disk 147 or the second rotating disk 148.In this case, because the first school extension 133 is identical with the physical dimension of the second school extension 134, as long as require so the material being arranged on the school extension 132 in the first rotating disk 147 and the second rotating disk 148 can make the neutron beam quality obtained after slow body 13 can reach expection, actually or and do not have requirement to the first school extension 133 second school extension 134 installed in the first rotating disk 147 and the second rotating disk 148.When the overall structure of slow body 13 is cylinders, or cone or be the combination of cylinder and cone time, when first school extension 133 is different with the physical dimension of the second school extension 134, the neutron beam quality requirements obtained as required selects the first school extension 133 and the second school extension 134 of different materials, first school extension 133 can only correspondence be installed in the first rotating disk 147, and the second school extension 134 also can only correspondence be installed in the second rotating disk 148.
Reflector 14 also comprises the supplementary reflector 145 ' being located at school extension 132 periphery, supplementing after reflector 145 ' can make an entirety with school extension 132 is installed in rotating disk 146, also can be installed on separately in rotating disk 146 after school extension 131 is installed on rotating disk 146.When school extension 132 is installed on basilar part 131 rear around rotating shaft Z rotation, supplement reflector 145 ' jointly to reflect the neutron of scattering with the reflector 14 be enclosed in outside basilar part 131, to make the neutron of scattering be reflected back toward on the main shaft of neutron beam, to improve the intensity of beam of epithermal neutron.
Slow body 13 is made by having the material that fast neutron action section is large, epithermal neutron action section is little, and as one preferably, slow body 13 is by Al, Pb, Ti, Bi, C, D
2o, AlF
3, Fluental
tM, CaF
2, Li
2cO
3, MgF
2and Al
2o
3in at least one make, further illustrate, the basilar part 131 of slow body 13 is by Al, Pb, Ti, Bi, C, D
2o, AlF
3, Fluental
tM, CaF
2, Li
2cO
3, MgF
2and Al
2o
3in at least one or severally to make, the material of the first school extension 133 and the second school extension 134 is also by Al, Pb, Ti, Bi, C, D
20, AlF
3, Fluental
tM, CaF
2, Li
2cO
3, MgF
2and Al
2o
3in at least one or severally to make.That is, in the application, the material of the first school extension 133, second school extension 134 and basilar part 131 can be consistent with each other, also can be different from each other.Reflector 14 is made up of the material having neutron reflection ability strong, and as a kind of preferred embodiment, reflector 14 is made up of at least one in Pb or Ni.
In addition, the rear end of slow body 13 can be provided with thermal neutron absorber (not shown), clearance channel 18 is provided with between slow body 13 and reflector 14, be provided with air duct 19 between thermal neutron absorber and beam outlet 17, in reflector 14, be provided with the radiation shield 16 of the normal tissue dose that can reduce non-irradiated district.So-called clearance channel 18 refers to the region easily allowing neutron beam pass through of the sky do not covered with solid material, and this clearance channel 18 can be set to air passage or vacuum channel.Clearance channel 18 the flux that can improve epithermal neutron is set, arranging of air duct 19 can continue the neutron departing from neutron beam main shaft to be led back to main shaft to improve epithermal neutron intensity of beam.Radiation shield 16 comprises shielding the photon shielding 161 of seepage photon in neutron beam and the neutron shield 162 in order to shield seepage neutron in neutron beam.Photon shielding 161 can be set to one with reflector 14, also can be arranged to split type, and neutron shield 162 can be arranged on the position of contiguous beam outlet 17.
Nuclear reaction is there is to produce neutron with target 12 in proton beam from beam entrance 11 incidence, neutron forms neutron beam, neutron beam limits a beam main shaft, formed neutron beam through slow body 13 by neutron degradation to epithermal neutron energy district, thermal neutron absorber absorbs the thermal neutron in neutron beam, with avoid treatment time and shallow-layer normal structure caused multiple dose, the neutron departing from beam main shaft is led back to beam main shaft to improve epithermal neutron intensity of beam by reflector 14, thus obtains the beam quality meeting this patient treatment most.
Thermal neutron absorber is made up of the material large with thermal neutron action section, as a kind of preferred embodiment, thermal neutron absorber by
6li makes.As one preferably, the material selection lead (Pb) of photon shielding 161 is made, and the material selection polyethylene (PE) of neutron shield is made.Well known to those skilled in the art, photon shielding 161 can be made up of other materials, as long as play the effect of shielding photon, neutron shield 162 also can be made up of other materials, also can be arranged on other local, as long as the condition of shielding seepage neutron can be met.
The beam-shaping body of the application's neutron capture treatment only needs to select the slow ability of slow body to neutron of different materials to adjust according to the actual requirement of the indexs such as the intrafascicular subzone of tumor correlation, neutron beam flux, same armarium just can be used to treat different patient, structure is simple, and the suitability is strong.
The beam-shaping body for neutron capture treatment that the application discloses is not limited to the content described in above embodiment and the structure represented by accompanying drawing.The change apparently that the basis of the application is made the material of wherein component, shape and position, to substitute or amendment, all within the scope that this application claims protection.
Claims (10)
1. the beam-shaping body for neutron capture treatment, it is characterized in that: described beam-shaping body comprise beam entrance, target, be adjacent to target slow body, be enclosed in described reflector external slowly and beam outlet, described target and the proton beam generation nuclear reaction from the incidence of described beam entrance are to produce neutron, described slow body is by slow for the neutron produced from described target, the neutron departed from leads back to described slow body to improve epithermal neutron intensity of beam by described reflector, and described slow body can be changed to adjust the slow ability of slow body to neutron.
2. the beam-shaping body for neutron capture treatment according to claim 1, it is characterized in that: described slow body comprises the basilar part being positioned at target rear and the school extension arranged with basilar part split, described school extension can be changed separately to adjust the slow ability of slow body to neutron.
3. the beam-shaping body for neutron capture treatment according to claim 2, it is characterized in that: described basilar part is adjacent to target rear and fixes with target, described school extension is installed on the rear of basilar part and is adjacent to basilar part.
4. the beam-shaping body for neutron capture treatment according to claim 2, it is characterized in that: described school extension at least comprises the first school extension and the second school extension, described first school extension is installed on basilar part rear and is adjacent to basilar part, second school extension is installed on the first school extension rear and is adjacent to the first school extension, and described first school extension and the second school extension can be changed separately.
5. the beam-shaping body for neutron capture treatment according to claim 4, it is characterized in that: the corresponding school extension of described reflector offers the guide groove extending to basilar part rear, described guide groove is provided with slide rail, and described school extension is installed on and moves to basilar part rear by slide rail after in guide groove and be adjacent to basilar part; Described guide groove at least comprise corresponding with the first school extension the first guide groove and with the second school extension relative to the second guide groove; When described first school extension only material identical with the physical dimension of the second school extension is different, the first school extension and the second school extension can be arranged in the first guide groove or the second guide groove respectively; When the first school extension and material different with the physical dimension of the second school extension is also different, described first school extension is installed in the first guide groove, and described second school extension is installed in the second guide groove.
6. the beam-shaping body for neutron capture treatment according to claim 5, it is characterized in that: reflector also comprises to be located at outside school extension two and the supplementary reflector be installed in guide groove, when school extension to be installed on the rear of basilar part by slide rail, supplement reflector and the reflector be enclosed in outside basilar part reflects the neutron of scattering jointly.
7. the beam-shaping body for neutron capture treatment according to claim 4, it is characterized in that: described reflector is provided with rotating shaft, described rotating shaft is provided with and is positioned at basilar part rear and can the rotating disk that rotates of opposed substrate portion, and described school extension is installed on after in rotating disk and is adjacent to basilar part with dial turning motion to basilar part rear; Described rotating disk at least comprises first rotating disk corresponding with the first school extension and second rotating disk corresponding with the second school extension; When described first school extension only material identical with the physical dimension of the second school extension is different, the first school extension and the second school extension can be arranged in the first rotating disk or the second rotating disk respectively; When the first school extension and material different with the physical dimension of the second school extension is also different, described first school extension is installed in the first rotating disk, and described second school extension is installed in the second rotating disk.
8. the beam-shaping body for neutron capture treatment according to claim 7, it is characterized in that: reflector also comprises the supplementary reflector being located at school extension periphery, when school extension around rotating shaft rotate be installed on basilar part rear time, supplement reflector and the reflector be enclosed in outside basilar part and jointly the neutron of scattering reflected.
9. the beam-shaping body for neutron capture treatment according to claim 3, is characterized in that: the material of described basilar part, the first school extension and described second school extension all can by Al, Pb, Ti, Bi, C, D
2o, AlF
3, Fluental
tM, CaF
2, Li
2cO
3, MgF
2and Al
2o
3in any one or a few make.
10. the beam-shaping body for neutron capture treatment according to claim 5 or 7, is characterized in that: described reflector is made up of at least one in Pb or Ni, and the material of described supplementary reflector is identical with the material of reflector.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520770873.0U CN205073543U (en) | 2015-09-30 | 2015-09-30 | Beam shaper for neutron -capture therapy |
| JP2018516559A JP6722281B2 (en) | 2015-09-30 | 2016-07-12 | Beam shaper used for neutron capture therapy |
| EP16850172.4A EP3342458B1 (en) | 2015-09-30 | 2016-07-12 | Beam shaper for neutron capture therapy |
| PCT/CN2016/089731 WO2017054548A1 (en) | 2015-09-30 | 2016-07-12 | Beam shaper for neutron capture therapy |
| US15/918,262 US10898733B2 (en) | 2015-09-30 | 2018-03-12 | Beam shaping assembly for neutron capture therapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520770873.0U CN205073543U (en) | 2015-09-30 | 2015-09-30 | Beam shaper for neutron -capture therapy |
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| CN205073543U true CN205073543U (en) | 2016-03-09 |
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| WO2017054548A1 (en) * | 2015-09-30 | 2017-04-06 | 南京中硼联康医疗科技有限公司 | Beam shaper for neutron capture therapy |
| CN107240430A (en) * | 2016-03-28 | 2017-10-10 | 南京中硼联康医疗科技有限公司 | Screening arrangement for beam-shaping body |
| CN108156742A (en) * | 2016-12-02 | 2018-06-12 | 财团法人工业技术研究院 | Neutron beam source generator and filter screen thereof |
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| CN109925606A (en) * | 2017-12-15 | 2019-06-25 | 南京中硼联康医疗科技有限公司 | Neutron capture treatment system |
| RU2745133C1 (en) * | 2017-08-30 | 2021-03-22 | Нойборон Медтех Лтд. | Neutron capture therapy system |
| RU2777655C1 (en) * | 2021-03-16 | 2022-08-08 | Степан Сергеевич Салодкин | Method for cooling of front side of solid-state target during irradiation with charged particle beam |
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|---|---|---|---|---|
| WO2017054548A1 (en) * | 2015-09-30 | 2017-04-06 | 南京中硼联康医疗科技有限公司 | Beam shaper for neutron capture therapy |
| US10898733B2 (en) | 2015-09-30 | 2021-01-26 | Neuboron Medtech Ltd. | Beam shaping assembly for neutron capture therapy |
| CN107240430A (en) * | 2016-03-28 | 2017-10-10 | 南京中硼联康医疗科技有限公司 | Screening arrangement for beam-shaping body |
| CN107240430B (en) * | 2016-03-28 | 2024-03-22 | 南京中硼联康医疗科技有限公司 | Shielding device for beam shaping body |
| US11109476B2 (en) | 2016-12-02 | 2021-08-31 | Heron Neutron Medical Corp. | Filter |
| CN108156742A (en) * | 2016-12-02 | 2018-06-12 | 财团法人工业技术研究院 | Neutron beam source generator and filter screen thereof |
| US10791618B2 (en) | 2016-12-02 | 2020-09-29 | Heron Neutron Medical Corp. | Neutron beam source generator and filter |
| US11198023B2 (en) | 2017-08-30 | 2021-12-14 | Neuboron Medtech Ltd. | Neutron capture therapy system |
| RU2745133C1 (en) * | 2017-08-30 | 2021-03-22 | Нойборон Медтех Лтд. | Neutron capture therapy system |
| WO2019056989A1 (en) * | 2017-09-25 | 2019-03-28 | 合肥中科离子医学技术装备有限公司 | Energy selection system for superconducting proton apparatus and implementation method therefor |
| CN109925606A (en) * | 2017-12-15 | 2019-06-25 | 南京中硼联康医疗科技有限公司 | Neutron capture treatment system |
| CN109925606B (en) * | 2017-12-15 | 2024-03-22 | 南京中硼联康医疗科技有限公司 | Neutron capture therapy system |
| RU2777655C1 (en) * | 2021-03-16 | 2022-08-08 | Степан Сергеевич Салодкин | Method for cooling of front side of solid-state target during irradiation with charged particle beam |
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