CN205041923U - Device that lung's disease spraying was dosed - Google Patents
Device that lung's disease spraying was dosed Download PDFInfo
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- CN205041923U CN205041923U CN201520549801.3U CN201520549801U CN205041923U CN 205041923 U CN205041923 U CN 205041923U CN 201520549801 U CN201520549801 U CN 201520549801U CN 205041923 U CN205041923 U CN 205041923U
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- spring
- motion block
- pipette
- quiet piece
- medicine bottle
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Abstract
The utility model provides a device that lung's disease spraying was dosed sets up down the lower shell of spring including bottom, lower part, during the spring is arranged down in to the medicine bottle, medicine bottle mouth and motion block card and, a pipette top -down runs through quiet piece, upper spring, motion block in proper order and inserts the drug bottle, the pipette is fixed on the motion block, and the check valve is adorned on the pipette top, quiet piece top slight nozzle of installation and filter, gland connection is gone up on last barrel to the last barrel suit of top area suction nozzle outside quiet piece and last spring, outer cover has round helping hand spring on last barrel lower part and barrel upper portion down between lower barrel and the overcoat, and the recess that has round and lower barrel to have a perfect understanding is inwards opened along the circumferencial direction in the overcoat lower part, trompil on the recess, and the downthehole steel ball of respectively laying, the circumferencial direction is followed on 13 on motion block upper portion division has the bayonet socket, a screw rod is fixed on the overcoat, and the screw rod lower extreme passes through fine screw thread and connects the pointer, and the pointer is carved with the count scale all around. The utility model discloses can spray many times and dose to the lung through the oral cavity.
Description
Technical field
This utility model relates to technical field of medical instrument, particularly relate to a kind of Respiratory Medicine, about pulmonary disease, the spray inhalation administration device that can quantitatively, repeatedly spray.
Background technology
In recent years because the factors such as serious problem of environmental pollution, air pollution constantly worsen, the sickness rate of chronic obstructive pulmonary disease (COPD), asthma and some respiratory tract diseases is made to be rising situation.
But, for pulmonary disease, or respiratory tract disease, drug administration, or injection all cannot make medicine directly act on focus, on the contrary through numerous organs such as livers, enters systemic blood circulation.The organs such as liver often have first pass effect, and namely they are oneself and unwanted drug absorption, have damaged these organs on the contrary.At present in the world, some developed countries have entered into by the stage directly medicine being sucked pulmonary through respiratory tract for the treatment of pulmonary disease.This respiratory tract that passes through is directly by the medication good effect of drug effect in pulmonary, and instant effect, can make medicine directly act on focus, and other position side effect for health are little, is a kind of FA medication.
Pulmonary administration has that sorbent surface is long-pending large, absorption site blood flow abundant, can avoid liver first-pass effect and epithelial barrier is thin, membrane permeability advantages of higher, and therapeutic domain expands, and is more and more paid attention to.
Spraying sucks pulmonary administration and has many-sided superiority, first Inhalation in Treating can make medicine directly get to target organ, i.e. the lung of patient and bronchus, therefore require lung and bronchial local concentration higher, onset speed is faster, can alleviate the symptom of patients with COPD so at short notice.Secondly, the dosage of inhalation-type drug administration institute drug is more much smaller than dosage that is oral and the required medicine of injection.Such as, general oral drugs need 8 milligrams and Sucked medicine only needs 0.2 milligram, although the consumption of Sucked medicine is oral 1/40, effect for chronic obstructive pulmonary disease air flue better, and less to the side effect of whole body.Secondly, the chemical degradation of pulmonary and enzymatic degradation react lower, and the degree that therefore medicine is destroyed is little.Adult about has 3 ~ 400,000,000 alveolars, and the gross area can reach 7 ~ 100 square metres, and the effective surface area of mucous membrane of small intestine microvilli is roughly the same, can the larger proteins and peptides medicine of high-efficiency delivery molecular mass.Huge respiratory surface is the basis that lung has good absorption ability.
It has been recognized that inhalation is the most simple and effective route of administration of the above-mentioned disease for the treatment of.Inhalation in Treating also can be used for the treatment of other pulmonary infections such as influenza, pulmonary carcinoma simultaneously.
The RESPIMAT atomized medicine introducing device that Germany Bo Linge Yin Ge company (Boehringer-ingelheim) releases is quantitatively the most accurate in the world at present, uses most convenient, the doser that nebulisation time is longer.The COPD new drug SpirivaRespimat of the said firm's exploitation have successfully been obtained the approval of FDA in JIUYUE, 2014.This drug use be do not rely on air to send quickly through the mode of inhaler, but directly acted on the new method of focus through respiratory tract by oral cavity by a kind of aerosol slowly sent.Can doubly find pleasure in (Respimat) just as the suction apparatus of this newtype drug, patient can be allowed to suck the subparticle of atomization at leisure with the characteristic of its " soft mist ", improve the deposition of medicine in pulmonary, simultaneously easily by chronic obstructive pulmonary disease, asthmatic patient are accepted.
A lot of drug research unit of China has has researched and developed the medicine that can be directly used in anapnotherapy, is badly in need of the doser that phase should be able to be supporting.
Summary of the invention
For the shortage of the doser of China's independent development and the demand in market, this utility model provide a kind of for pulmonary disease, the spray inhalation administration device that can quantitatively and repeatedly spray.
This utility model is achieved through the following technical solutions:
A kind of pulmonary disease spray delivery device, it is characterized in that, described device comprises: the lower shell being sealed lower end by bottom, lower spring is arranged at the bottom in lower shell, medicine bottle is placed in lower spring, and the motion block above medicine bottle is by the draw-in groove and the medicine bottle card that agree with mutually with medicine bottle bottleneck of its lower end and be connected; Slave Block upwards sets gradually spring and one quiet piece, pipette run through successively from top to bottom quiet piece, upper spring, motion block insert medicine bottle;
Pipette is clamped to motion block upper end by clamping device, sealing gland with sealing ring is set in pipette and is connected to quiet piece of lower end, pipette upper end is provided with a check valve below filter, trickle nozzle bottom put into by filter, and trickle nozzle base stretches out quiet piece of top and is connected with quiet piece; One upper shell is sleeved on outside quiet piece and upper spring, and upper shell top extends upward a suction nozzle; One upper press cover is connected on upper shell, downward from upper press cover edge, a coat suit with upper flange is on upper shell and lower shell top, a circle power assistant spring is provided with between lower shell and overcoat, lower shell bottom has 3 ~ 6 apertures along a circumferencial direction, respectively laid a steel ball in aperture, be enclosed within outward and have a circle and the through groove of lower shell with steel ball corresponding position along the circumferential direction, motion block top 1/3 place along the circumferential direction has a circle bayonet socket;
A screw rod is fixing on the coat, and screw rod lower end is by fine thread concatenation pointer, and pointer surrounding is carved with numeration scale.
The bottleneck of described medicine bottle is provided with sealing ring, and a sealing gasket seals bottleneck.
Described upper press cover can adopt with upper shell be threaded, cementing or buckle is connected.
Described sealing gland with quiet piece can adopt be threaded, cementing or buckle is connected.
Described suction nozzle is provided with a protective sleeve.
Described clamping device is mechanical gripping devices, utilizes nut to tighten the gasket ring of a fluting, pipette is fixed in motion block.
Beneficial effect
The spray delivery device of pulmonary disease anapnotherapy described in the utility model, has features:
(1) upper and lower two springs are housed in doser.When pressing doser, upper and lower two springs are compressed simultaneously.Lower spring, when compression puts in place, has a clamp, temporarily blocks lower spring.And upper spring does not have clamp, after the pressing, upper spring can release automatically.
(2) pipette and motion block are fixed together, and motion block is as large piston, and pipette, as valve piston, is pressurized to high pressure the medicinal liquid in quiet piece.
(3) upper spring is when discharging, and promotes quiet piece, and also namely high pressure piston cylinder moves forward, and at this moment one-way valve opens, pipette is from drawing the medicinal liquid of ormal weight in medicine bottle in high pressure piston cylinder.
(4) being contained after in mouth by doser, press release-push, lower spring discharges, and promote large piston and move forward, large piston driving valve piston, plays the effect of pressure multiplier, the medicinal liquid in valve piston is added and is pressed into high-pressure medicine liquid.
(5) high pressure medicinal liquid is sprayed into the medicinal liquid of atomization shape by minute nozzle.Along with the suction action of mouth, the medicinal liquid of atomization is drawn onto pulmonary, allows the fine medicinal liquid of atomization be applied directly to the focal area of pulmonary.Play the most direct therapeutical effect.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of spray delivery device at collecting state.
Wherein, 1: bottom, 2: lower spring, 3: medicine bottle, 4: lower shell, 5: pipette, 6: sealing ring, 7: sealing gasket, 8: steel ball, 9: motion block, 10: overcoat, 11: bayonet socket, 12: resistance spring, 13: clamping device, 14: upper spring; 15: sealing gland, 16:O type circles, 17: upper flange, 18: upper press cover, 19: quiet piece, 20: upper shell, 21: check valve, 22: filter, 23: trickle nozzle, 24: suction nozzle.
Fig. 2 is the schematic diagram at the spray delivery device back side, can see counting scale and pointer thereof.
Wherein, 25: screw rod, 26: pointer, 27: protective sleeve.
Fig. 3 is the schematic diagram of the first step of operation doser
Fig. 4 is the schematic diagram of the second step of operation doser
Fig. 5 is the schematic diagram of the 3rd step of operation doser
Detailed description of the invention
Below in conjunction with detailed description of the invention, this utility model is further elaborated.
As shown in Figure 1, when starting medication, take off bottom 1 and just can load medicine bottle 3.Take away the bottle cap of medicine bottle 3, vertically put on the table, medicine bottle is put into inner barrel 4, allow pipette 5 insert medicine bottle.Vertical pressing doser, lower spring is compressed, and medicine bottle can be pressed into bottleneck sealing ring 6, and contacts with bottle sealing pad 7 and compress, and at this moment medicine bottle just loads doser.Bottleneck sealing ring 6 and bottle sealing pad 7 make the medicinal liquid in medicine bottle to leak out.Load onto bottom 1, this doser just can employ.
During medication, arrest doser upper shell 20, down press, motion block 9 has bayonet socket 11, and during pressing, motion block down moves, and compression lower spring 2, until bayonet socket 11 runs into steel ball, is blocked by steel ball temporarily.At this moment go up lower spring to be compressed simultaneously.See Fig. 3.
When idle state, steel ball is positioned at the steel ball hole of lower shell and the steel bead groove of overcoat, when preparing administration, on pressing cylindrical shell top, steel ball, by the steel bead groove that snaps between inner barrel and motion block temporarily, makes lower spring temporarily be pinned under compression, once axially apply some thrusts, steel ball can skid off in the groove of Slave Block at once, thus release lower spring.
Decontrol pressing, because upper spring 14 is not stuck, it can loosen automatically.Quiet piece 19 can up be released when loosening by upper spring, is at this moment equivalent to pipette 5 as piston at piston cylinder, namely moves within quiet piece 19.At this moment check valve 21 is opened, and sucks the medicinal liquid of ormal weight when upper spring 14 promotes quiet piece 19 motion.See Fig. 4.
The suction nozzle 24 of doser is contained in the mouth.Pinch the outer flange 17 that puts of pressure and upper press cover 18 with hands, the resistance spring 12 in overcoat is compressed, and plays the effect that power-assisted promotes, and axial thrust is applied on the steel ball 8 that is stuck in bayonet socket.Unstable block state because steel ball 8 is in, once be subject to axial thrust, steel ball can skid off in bayonet socket 11, and lower spring 2 is sharply recovered by the state compressed.The spring force of outburst is by the pipette 5 on related for motion block 9 motion block, and sharply up advance, this pipette 5 to bear the thick-walled pipe of high pressure, and it plays the effect of piston in quiet piece 19.Pipette 5 must interfix with motion block 9, and 13 is clamping devices pipette 5 be clamped on motion block 9.15 and 16 is dynamic sealing devices pipette moved in quiet piece 19 as piston.Wherein 16 is O shape circles, and 15 is sealing glands.Cycle spring 12 is the effects playing power-assisted promotion in release lower spring 2.Lower spring 2 promotes motion block and moves together with pipette, and motion block 9 plays the effect of a large piston, and the pipette 5 done by high pressure thick-walled pipe plays the effect of valve piston in quiet piece 19.It plays pipette in bottom, and on the top of pipette, coordinates with check valve, plays the effect of high-pressure mini piston.
Large and small piston plays the effect of pressure multiplier, the medicinal liquid sucked is pressurized to the state of high pressure.The medicinal liquid of high pressure, through minute nozzle passage, by medical liquid atomizing, is drawn onto in lung, completes the process of administration.The state of having sprayed can see Fig. 5.
Fig. 2 shows the counting assembly that can work asynchronously with doser.While pressing energizing spring, screw rod 25 is driven rotation one to enclose by nut while pressing, and the pointer 26 on screw thread is passed by a pitch.When spring discharges, the nut promoting screw rotation unclamps, so pointer can only one-way movement.It indicates compression number, represents the access times of doser.
Fig. 3 is the first step of operation doser: pressing, at this moment go up lower spring and be all compressed, lower spring 2 is stuck in bayonet socket 11 by steel ball 8, temporarily can not discharge.And upper spring 14 is not stuck, can release automatically after pressing.
Fig. 4 is the second step of operation: wait for, only need time several seconds, at this moment go up spring 14 and discharged, piston falls back on finally, is actually a piston cylinder, also namely shifts topmost onto for quiet piece 19, at this moment check valve is opening, the medicinal liquid of suction ormal weight in pipette.
Fig. 5 is the 3rd step of operation: spray, and pinches the flange 17 on pressure overcoat 10 and upper press cover 18, is equivalent to promote quiet piece 19 and motion block 9, and allow the steel ball 8 on motion block 9 skid off bayonet socket 11, the spring 12 in overcoat plays the effect of power-assisted.Lower spring 2 is when discharging, promoted motion block 9, the pipette 5 on motion block 9, this is high pressure thick-walled pipe, play by motion block 9 as large piston, drive pipette 5 as valve piston, compress quiet piece 19 as the medicinal liquid in piston cylinder, medicinal liquid is pressurized to high pressure conditions, high pressure medicinal liquid is through filter 22, enter minute nozzle 23, the gap of fine adjustment nozzle (the trickle cap of spraying nozzle can), be inhaled in lung after atomization immediately and play therapeutical effect.
After completing above-mentioned steps, by suction nozzle 24 wiped clean, protective sleeve 27 is put, to protect suction nozzle cleaning.
The dose that this utility model regulates pipette to suck by the stroke of regulating piston, namely regulates the distance between quiet piece and motion block corresponding difference can suck dose.Because dosage is the consumption that doctor's advice specifies, arranged according to the regulation of medicine by manufacturer, user can not regulate dosage voluntarily.
Claims (5)
1. the device of a pulmonary disease spray delivery, it is characterized in that, described device comprises: the lower shell being sealed lower end by bottom, lower spring is arranged at the bottom in lower shell, medicine bottle is placed in lower spring, and the motion block above medicine bottle is by the draw-in groove and the medicine bottle card that agree with mutually with medicine bottle bottleneck of its lower end and be connected; Slave Block upwards sets gradually spring and one quiet piece, pipette run through successively from top to bottom quiet piece, upper spring, motion block insert medicine bottle;
Pipette is clamped to motion block upper end by clamping device, sealing gland with sealing ring is set in pipette and is connected to quiet piece of lower end, pipette upper end is provided with a check valve below filter, trickle nozzle bottom put into by filter, and trickle nozzle base stretches out quiet piece of top and is connected with quiet piece; One upper shell is sleeved on outside quiet piece and upper spring, and upper shell top extends upward a suction nozzle; One upper press cover is connected on upper shell, downward from upper press cover edge, a coat suit with upper flange is on upper shell and lower shell top, a power assistant spring is provided with between lower shell and overcoat, lower shell bottom has 3 ~ 6 apertures along a circumferencial direction, respectively laid a steel ball in aperture, be enclosed within outward and have a circle and the through groove of lower shell with steel ball corresponding position along the circumferential direction, motion block top 1/3 place along the circumferential direction has a circle bayonet socket;
A screw rod is fixing on the coat, and screw rod lower end is by fine thread concatenation pointer, and pointer surrounding is carved with numeration scale.
2. the device of pulmonary disease spray delivery as claimed in claim 1, it is characterized in that, the bottleneck of described medicine bottle is provided with sealing ring, and a sealing gasket seals bottleneck.
3. the device of pulmonary disease spray delivery as claimed in claim 1, is characterized in that, described upper press cover and the connected mode of upper shell be threaded, cementing or buckle be connected in one; Described sealing gland and the connected mode of quiet piece be threaded, cementing or buckle be connected in one.
4. the device of pulmonary disease spray delivery as claimed in claim 1, it is characterized in that, described suction nozzle is provided with a protective sleeve.
5. the device of pulmonary disease spray delivery as claimed in claim 1, it is characterized in that, described clamping device is mechanical gripping devices.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520549801.3U CN205041923U (en) | 2015-07-27 | 2015-07-27 | Device that lung's disease spraying was dosed |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520549801.3U CN205041923U (en) | 2015-07-27 | 2015-07-27 | Device that lung's disease spraying was dosed |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205041923U true CN205041923U (en) | 2016-02-24 |
Family
ID=55335544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520549801.3U Withdrawn - After Issue CN205041923U (en) | 2015-07-27 | 2015-07-27 | Device that lung's disease spraying was dosed |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205041923U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105148363A (en) * | 2015-07-27 | 2015-12-16 | 华东理工大学 | Spray administration device for treating pulmonary diseases |
-
2015
- 2015-07-27 CN CN201520549801.3U patent/CN205041923U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105148363A (en) * | 2015-07-27 | 2015-12-16 | 华东理工大学 | Spray administration device for treating pulmonary diseases |
| CN105148363B (en) * | 2015-07-27 | 2018-04-27 | 华东理工大学 | A kind of device of pulmonary disease spray delivery |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20160224 Effective date of abandoning: 20180427 |
|
| AV01 | Patent right actively abandoned |