CN205011679U - Full -automatic peptide synthesis appearance of multichannel - Google Patents
Full -automatic peptide synthesis appearance of multichannel Download PDFInfo
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- CN205011679U CN205011679U CN201520588279.XU CN201520588279U CN205011679U CN 205011679 U CN205011679 U CN 205011679U CN 201520588279 U CN201520588279 U CN 201520588279U CN 205011679 U CN205011679 U CN 205011679U
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Abstract
The utility model belongs to the technical field of the synthesizer, special design full -automatic peptide synthesis appearance of multichannel, store chamber, reagent storage chamber, solenoid valve, electrical apparatus case, reactor, holding frame, pivot, first synchronizing wheel, hold -in range, motor, second synchronizing wheel and glass reagent bottle including reaction chamber, amino acid, the reaction chamber is inside to be equipped with six reactors, and two liang installed on the holding frame, connect by hold -in range and the second synchronizing wheel on the motor through the epaxial three first synchronizing wheel of three commentaries on classics, lay a glass reagent bottle on the amino acid storage chamber. The utility model discloses need not testing personnel and synthetic personnel's the accuse of staring at, reach and alleviate workman intensity of labour, improve product quality's purpose.
Description
Technical field
The utility model belongs to synthesizer technical field, a kind of multi-channel full automatic Peptide synthesizer of special design.
Background technology
Existing, the manual liquid feeding mode of the many employings of domestic hyperchannel Peptide synthesizer carries out liquid feeding, and this mode needs to drop into suitable manpower and operates; Domestic full-automatic polypeptide synthetic instrument mostly is again single passage synthesis, this kind of mode cannot at the same time between inherent same portion synthesizer completes the synthesis of multiple polypeptides.The mode of multi-channel full automatic, just needs by the work of pipe section magnetic valve by hyperchannel with automatically perfectly combine.The Peptide synthesizer of the U.S. is also only single pass, and expensive, is not suitable with Chinese Enterprises, the making a big purchase in large quantities and using of institute.
Utility model content
The utility model provides a kind of multi-channel full automatic Peptide synthesizer, and wherein solvent enters reactor by magnetic valve, and circuit card Controlling solenoid valve and motor run, and drives multiple reactor to carry out synthetic work simultaneously.
The technical solution of the utility model is:
A kind of multi-channel full automatic Peptide synthesizer, comprise reaction chamber, amino acid storage chamber, reagent storage chamber, magnetic valve, electric appliance box, reactor, holding frame, rotating shaft, the first synchronizing wheel, Timing Belt, motor, the second synchronizing wheel and glass reagent bottle, described reaction chamber inside is provided with six reactors, and be arranged between two on holding frame, linked by Timing Belt and the second synchronizing wheel on motor by three the first synchronizing wheels in three rotating shafts, described amino acid storage chamber lays a glass reagent bottle.
Preferably, described electric appliance box is connected with upper computer by usb line, and Controlling solenoid valve closes disconnection work.
Preferably, described reactor does 180 ° or 270 ° of rotations are waved, and the amino acid, the solvent that make to enter reactor fully contact and react.
Preferably, described electric appliance box 5 is provided with pLC controller 14, circuit power 15 and circuit card 16.
Preferably, described motor is servomotor.
The beneficial effects of the utility model are:
1, the utility model is the nitrogen of solenoid control external pressurized, make reagent or amino acid by the fluid path inflow reactor on magnetic valve, or the pipeline that cleaning amino acid flows through, not only can carry out small-sized laboratory synthesis, can also small-scale industrial production be carried out.
2, the utility model can provide the small-scale of laboratory and factory to synthesize, to need to carry out multiple short run, test synthesis very applicable, and stare at control without the need to testing crew and synthesis personnel, reach and alleviate labor strength, the object of improving the quality of products.
3, the utility model has equipment novelty, and compact construction is reasonable, and maintaining is easy, and long-time continuous uses, and operating performance is stablized, and reduces personnel attrition, expands and synthesize the advantages such as multiple polypeptides simultaneously.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model;
Fig. 2 is the sectional view of the utility model reaction chamber;
Fig. 3 is part sectioned view of the present utility model.
Wherein:
1-reaction chamber, 2-amino acid storage chamber, 3-reagent storage chamber, 4-magnetic valve, 5-electric appliance box, 6-reactor, 7-holding frame, 8-rotating shaft, 9-first synchronizing wheel, 10-Timing Belt, 11-motor, 12-second synchronizing wheel, 13-glass reagent bottle, 14-pLC controller, 15-circuit power, 16-circuit card.
Embodiment
Below in conjunction with embodiment and Figure of description, the utility model is described in further detail, but embodiment of the present utility model is not limited thereto.
A kind of multi-channel full automatic Peptide synthesizer, comprise reaction chamber 1, amino acid storage chamber 2, reagent storage chamber 3, magnetic valve 4, electric appliance box 5, reactor 6, holding frame 7, rotating shaft 8, first synchronizing wheel 9, Timing Belt 10, motor 11, second synchronizing wheel 12 and glass reagent bottle 13, described reaction chamber 1 inside is provided with six reactors 6, and be arranged on holding frame 7 between two, linked by Timing Belt 10 and the second synchronizing wheel 12 on motor 11 by three the first synchronizing wheels 9 in three rotating shafts 8, described amino acid storage chamber 2 is laid 24 glass reagent bottles 13.
Further, described electric appliance box 5 is connected with upper computer by usb line, and Controlling solenoid valve 4 closes disconnection work.
Further, described reactor 6 does 180 ° or 270 ° of rotations are waved, and the amino acid, the solvent that make to enter reactor fully contact and react.
Further, described motor 11 is servomotor.
Further, described electric appliance box 5 is provided with pLC controller 14, circuit power 15 and circuit card 16.
Further, described circuit card 16 sends instruction, then by the work of circuit card 16 Controlling solenoid valve 4, motor 11, can gather some feedback data, the feedback of such as sensor or other additional functions simultaneously.
Further, synthesizer mainly adopts solenoid control to control fluid path, carries out amino acid, the measuring and transfer of solvent, instead of amino acid whose artificial injection; And automatically complete the cleaning of the fluid path after each feed liquor.
Further, synthesizer completes man-machine dialogue by the software of upper computer, is that electric box sends folding instruction to magnetic valve, completes magnetic valve action.
This hyperchannel full application of brake Peptide synthesizer, mainly adopts that private takes motor, Timing Belt, synchronizing wheel drive multiple reactor to synthesize simultaneously, the combination of software control magnetic valve, controls amino acid, the automatic measurement of solvent, transfer and fluid path cleaning.During design, adopt multiple reactor to work simultaneously, can at the same time in complete the synthesis of multi items peptide, automatically control to greatly reducing in manual monitoring building-up process to add amino acid whose operation, this serves saves artificial cost, can by the synthesis of more fund input polypeptide and research and development.This equipment can require according to user the synthesis simultaneously completing polypeptide, and completes Peptide systhesis under no worker monitor.
The announcement of book and instruction according to the above description, the utility model those skilled in the art can also change above-mentioned embodiment and revise.Therefore, the utility model is not limited to above-mentioned embodiment, and any apparent improvement of every those skilled in the art done by basis of the present utility model, replacement or modification all belong to protection domain of the present utility model.In addition, although employ some specific terms in this specification sheets, these terms just for convenience of description, do not form any restriction to the utility model.
Claims (5)
1. a multi-channel full automatic Peptide synthesizer, it is characterized in that: comprise reaction chamber, amino acid storage chamber, reagent storage chamber, magnetic valve, electric appliance box, reactor, holding frame, rotating shaft, the first synchronizing wheel, Timing Belt, motor, the second synchronizing wheel and glass reagent bottle, described reaction chamber inside is provided with six reactors, and be arranged between two on holding frame, linked by Timing Belt and the second synchronizing wheel on motor by three the first synchronizing wheels in three rotating shafts, described amino acid storage chamber lays a glass reagent bottle.
2. a kind of multi-channel full automatic Peptide synthesizer according to claim 1, is characterized in that: described electric appliance box is connected with upper computer by usb line, and Controlling solenoid valve closes disconnection work.
3. a kind of multi-channel full automatic Peptide synthesizer according to claim 1, is characterized in that: described reactor does 180 ° or 270 ° of rotations are waved, and the amino acid, the solvent that make to enter reactor fully contact and react.
4. a kind of multi-channel full automatic Peptide synthesizer according to claim 1, is characterized in that: described electric appliance box is provided with PLC, circuit power and circuit card.
5. a kind of multi-channel full automatic Peptide synthesizer according to claim 1, is characterized in that: described motor is servomotor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520588279.XU CN205011679U (en) | 2015-08-07 | 2015-08-07 | Full -automatic peptide synthesis appearance of multichannel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520588279.XU CN205011679U (en) | 2015-08-07 | 2015-08-07 | Full -automatic peptide synthesis appearance of multichannel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205011679U true CN205011679U (en) | 2016-02-03 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201520588279.XU Active CN205011679U (en) | 2015-08-07 | 2015-08-07 | Full -automatic peptide synthesis appearance of multichannel |
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| CN (1) | CN205011679U (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106986916A (en) * | 2017-03-20 | 2017-07-28 | 珠海百世瑞生命科技有限公司 | Full automatic high efficiency solid phase peptide synthesizer and application method |
| CN108752418A (en) * | 2018-08-08 | 2018-11-06 | 湖南科技学院 | A kind of multichannel Peptide systhesis reaction unit and its operating method |
| CN111072749A (en) * | 2018-10-22 | 2020-04-28 | 海南建邦制药科技有限公司 | Polypeptide synthesizer |
| CN111072750A (en) * | 2018-10-22 | 2020-04-28 | 海南建邦制药科技有限公司 | Polypeptide synthesizer and control system thereof |
| CN113769700A (en) * | 2021-08-30 | 2021-12-10 | 长沙缔仑生物科技有限公司 | DNA/RNA industrial full-automatic synthesizer |
| CN114130346A (en) * | 2021-02-02 | 2022-03-04 | 申联生物医药（上海）股份有限公司 | Full-automatic solid-phase organic synthesis modular equipment |
-
2015
- 2015-08-07 CN CN201520588279.XU patent/CN205011679U/en active Active
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106986916A (en) * | 2017-03-20 | 2017-07-28 | 珠海百世瑞生命科技有限公司 | Full automatic high efficiency solid phase peptide synthesizer and application method |
| CN106986916B (en) * | 2017-03-20 | 2023-10-13 | 珠海百世瑞生命科技有限公司 | Full-automatic high-efficiency solid-phase polypeptide synthesizer and use method thereof |
| CN108752418A (en) * | 2018-08-08 | 2018-11-06 | 湖南科技学院 | A kind of multichannel Peptide systhesis reaction unit and its operating method |
| CN108752418B (en) * | 2018-08-08 | 2024-01-30 | 湖南科技学院 | Multichannel polypeptide synthesis reaction device and operation method thereof |
| CN111072749A (en) * | 2018-10-22 | 2020-04-28 | 海南建邦制药科技有限公司 | Polypeptide synthesizer |
| CN111072750A (en) * | 2018-10-22 | 2020-04-28 | 海南建邦制药科技有限公司 | Polypeptide synthesizer and control system thereof |
| CN111072750B (en) * | 2018-10-22 | 2023-04-18 | 海南建邦制药科技有限公司 | Polypeptide synthesizer and control system thereof |
| CN111072749B (en) * | 2018-10-22 | 2023-07-07 | 海南建邦制药科技有限公司 | Polypeptide synthesizer |
| CN114130346A (en) * | 2021-02-02 | 2022-03-04 | 申联生物医药（上海）股份有限公司 | Full-automatic solid-phase organic synthesis modular equipment |
| CN113769700A (en) * | 2021-08-30 | 2021-12-10 | 长沙缔仑生物科技有限公司 | DNA/RNA industrial full-automatic synthesizer |
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| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |