CN204995611U - Artifical shoulder sleeve patch of type is woven in segmentation that nanometer coating was decoratied - Google Patents
Artifical shoulder sleeve patch of type is woven in segmentation that nanometer coating was decoratied Download PDFInfo
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- CN204995611U CN204995611U CN201520721689.7U CN201520721689U CN204995611U CN 204995611 U CN204995611 U CN 204995611U CN 201520721689 U CN201520721689 U CN 201520721689U CN 204995611 U CN204995611 U CN 204995611U
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Abstract
The utility model provides an artifical shoulder sleeve patch of type is woven in segmentation that nanometer coating was decoratied, include: the upper arm bone section of weaving 1, the free fibre section 2 of tendon, the upper portion of the upper arm bone section of weaving 1 is provided with epiphysis hole 3, and internal surface, the surface of the upper arm bone section of weaving 1 are run through to epiphysis hole 3, the upper end of tendon free fibre section 2 is connected to the lower extreme of the upper arm bone section of weaving 1, the lower part of tendon free fibre section 2 is provided with tendon stomidium 4, and tendon stomidium 4 runs through internal surface, the surface of tendon free fibre section 2. The utility model provides a shoulder sleeve patch can improve the mechanical properties of rotator cuff injury neoplasty back porch sleeve tissue, and in the biological tendon knitting tissue characteristic that can the aspect can simulate shoulder sleeve and bone and be connected, this structure can strengthen the intrinsic healing latent energy of tendon, and then the success rate of improvement rotator cuff injury prosthesis simultaneously.
Description
Technical field
This utility model relates to surgical patch field, particularly, relates to the segmentation Weaving type artificial bone-head for shoulder that nano coating modifies and to tuck inside the sleeve sticking patch.
Background technology
Rotator cuff tear is common Shoulder joint, and sickness rate increases with advancing age and gradually.Rotator cuff tear is the common cause causing the reduction of shoulder arthralgia, mobility, miopragia, accounts for 60% of shoulder pathological changes.To through the invalid Patients with Rotator Cuff Injury After of expectant treatment and shoulder sleeve mass lesions patient, usually take surgical operation therapy to repair and tear tendon, thus ease the pain, and rebuild function of joint.
Tendon is the weak spot in shoulder sleeve repair process, especially when defect is larger, tractive in art the shoulder tissue sleeve attempting bulk to tear be fixed on injured before former attachment point comparatively difficult, when now needing to solve huge rotator cuff tear by shoulder sleeve structure enhancement techniques, head of humerus covers not enough problem, ensure the mechanical property of kposthesis back porch tissue sleeve, maintain stability and the function of shoulder joint.
Repairing the material of enhancement techniques much for takeing on sleeve at present, comprising autologous tissue, allohisto compatibility, heteroplasm and synthetic tissue etc., but all there is respective problem and application limitation in clinical practice.Autograft material is mainly derived from the tissues such as autologous fascia lata, tendon of long head of biceps brachii, autograft class sticking patch great advantage has good biological attribute, the general inflammatory reaction not causing body, extra wound may be brought to autologous when one of major defect is to draw materials, belong to " tearing Dong Qiang open; mend Xi Qiang ", shoulder joint stability can be affected for district's disease damage.Tissue graft material that allogeneic is undressed derives from homology shoulder tissue sleeve, allosome kneecap tendinous tissue, heel string tissue and quadriceps femoris tendon tissue etc. usually.The mechanical property guarantee that this kind of material shortage is stable, easily makes body produce immunoreation, there is the risk infecting infectious disease after transplanting, and limited source.Acellular tissue graft material class sticking patch mainly comprises two kinds: heteroplasm transplants: be mainly derived from the tissues such as the corium of animal, small intestinal, pericardium, as Restore, and Cuffpatch, Conexa, TissueMen etc.2. allograft: the dermal tissue or the fascia lata that are mainly derived from human skin.After physical method or the operation of chemical method acellular, although have good biocompatibility and the mechanical characteristic of stretch-proof, but because it is tissue-derived, the difference of processing method, sterilizing methods, the Mechanical loading intensity that its mechanical strength carries well below the primary tendon of human body or ligament.From biomechanics and biology angle, it does not have the inherent character of tendon itself.
Current shoulder sleeve patching material, the factors such as biomechanical strength, histocompatibility, source of drawing material problem, safety and expense all limit its application clinically.Therefore design mechanical strength excellent, the shoulder sleeve sticking patch of simulation shoulder tissue sleeve, good biocompatibility has important clinical value for treatment rotator cuff injury.
Utility model content
For defect of the prior art, the purpose of this utility model is to provide the segmentation Weaving type artificial bone-head for shoulder that a kind of nano coating modifies and tucks inside the sleeve sticking patch.
The segmentation Weaving type artificial bone-head for shoulder that a kind of nano coating provided according to this utility model is modified tucks inside the sleeve sticking patch, comprising: humerus braiding section 1, tendon free-fiber section 2;
The top of humerus braiding section 1 is provided with epiphysis hole 3, and inner surface, the outer surface of humerus braiding section 1 are run through in epiphysis hole 3;
The lower end of humerus braiding section 1 connects the upper end of tendon free-fiber section 2;
The bottom of tendon free-fiber section 2 is provided with tendon stomidium 4, and tendon stomidium 4 runs through inner surface, the outer surface of tendon free-fiber section 2;
Humerus braiding section 1 is rectangle or round rectangle with the integrant shape of tendon free-fiber section 2.
Preferably, epiphysis hole 3 is have draught line A, and tendon stomidium 4 is have draught line B.
Preferably, humerus braiding section 1 adopts the network structure of fibrage.
Preferably, epiphysis hole 3 and tendon stomidium 4 adopt any one mode following:
-epiphysis hole 3 is screw hole, and tendon stomidium 4 is hole of threading a needle;
-epiphysis hole 3 is band wire holdfast hole, and tendon stomidium 4 is hole of threading a needle;
-epiphysis hole 3 is hole of threading a needle, and tendon stomidium 4 is hole of threading a needle.
Preferably, upper face or all surfaces of humerus braiding section 1 are provided with coating I, and lower surface or all surfaces of tendon free-fiber section 2 are provided with coating II, are coated with coating III in humerus braiding section 1 with the junction of tendon free-fiber section 2;
Further, be specially:
-described coating III is the composite coating be made up of the material of coating I and the material of coating II;
-compared with coating I and/or coating II, described coating III contains different osteogenic growth factors, osteogenic growth medicine, becomes flesh somatomedin or becomes flesh growth medicine;
-described coating I, coating II, coating III are nano coating.
Preferably, the joint boundary line D indentation that the upper end that the lower end of described humerus braiding section 1 connects described tendon free-fiber section 2 is formed.
Preferably, described humerus braiding section 1 and the junction of tendon free-fiber section 2, refer to: the entirety be made up of humerus braiding section 1, tendon free-fiber section 2 includes one section of described joint boundary line D in the height direction.
Preferably, also comprise: self-deploy support A501, self-deploy support B502, self-deploy support C601, self-deploy support D602;
Humerus braiding section 1 is provided with through hole A7;
Self-deploy support A501 and self-deploy support B502 arranged in a crossed manner, and all through through hole A7;
Self-deploy support A501, self-deploy the upper end of support B502 be all fastenedly connected in humerus braiding section 1 outer surface;
Self-deploy support A501, self-deploy the lower end of support B502 be all fastenedly connected in humerus braiding section 1 inner surface;
Tendon free-fiber section 2 is provided with through hole B8;
Self-deploy support C601 and self-deploy support D602 arranged in a crossed manner, and all through through hole B8;
Self-deploy support C601, self-deploy the lower end of support D602 and be all fastenedly connected outer surface in tendon free-fiber section 2; Self-deploy support C601, self-deploy the upper end of support D602 and be all fastenedly connected inner surface in tendon free-fiber section 2.
Preferably, self-deploy support A501, self-deploy support B502, self-deploy support C601, self-deploy support D602 and be and adopt the strip laminated structure made of memorial alloy or rod-like structure;
Self-deploy support A501, self-deploy the concrete structure of support B502 and be: except top and bottom, the surface that remainder and humerus weave section 1 is separated;
Self-deploy support C601, self-deploy the concrete structure of support D602 and be: except top and bottom, the surface of remainder and tendon free-fiber section 2 is separated.
Preferably, also comprise: external protection 901, inner protective layer 902;
External protection 901, inner protective layer 902 are formed by a pieces of fabric 1001 and a free-fiber sheet 1002;
The pieces of fabric 1001 of external protection 901 covers the outer surface of humerus braiding section 1, and is positioned at the outside self-deploying support A501, self-deploy support B502;
The free-fiber sheet 1002 of external protection 901 covers the outer surface of tendon free-fiber section 2, and is positioned at the outside self-deploying support C601, self-deploy support D602;
The pieces of fabric 1001 of inner protective layer 902 covers the inner surface of humerus braiding section 1, and it is positioned at the inner side self-deploying support A501, self-deploy support B502;
The free-fiber sheet 1002 of inner protective layer 902 covers the inner surface of tendon free-fiber section 2, and is positioned at the inner side self-deploying support C601, self-deploy support D602.
Compared with prior art, this utility model has following beneficial effect:
The shoulder sleeve sticking patch that nano coating designed by this utility model is modified can improve the mechanical property of rotator cuff injury kposthesis back porch tissue sleeve, the tendon-bone healing tissue characteristics that shoulder sleeve is connected with bone can be simulated in biological property simultaneously, this structure can strengthen the healing potential of tendon inherence, and then improves the success rate of rotator cuff injury prosthesis.
Accompanying drawing explanation
By reading the detailed description done non-limiting example with reference to the following drawings, other features, objects and advantages of the present utility model will become more obvious:
Fig. 1 illustrates the structural representation of this utility model first embodiment.
Fig. 2, Fig. 3 illustrate the structural representation of the preference of this utility model first embodiment.
Fig. 4 illustrates the gathering of preference and the principle schematic of expansion of this utility model first embodiment.
Fig. 5 illustrates the structural representation of the change case of this utility model first embodiment.
In figure: D represents joint boundary line, E represents that the entirety be made up of humerus braiding section 1, tendon free-fiber section 2 includes one section of described joint boundary line D in the height direction.
Detailed description of the invention
Below in conjunction with specific embodiment, this utility model is described in detail.Following examples will contribute to those skilled in the art and understand this utility model further, but not limit this utility model in any form.It should be pointed out that to those skilled in the art, without departing from the concept of the premise utility, some changes and improvements can also be made.These all belong to protection domain of the present utility model.
As shown in Figure 1, the segmentation Weaving type artificial bone-head for shoulder that a kind of nano coating provided according to this utility model is modified tucks inside the sleeve sticking patch, comprising: humerus braiding section 1, tendon free-fiber section 2;
The top of humerus braiding section 1 is provided with epiphysis hole 3, and inner surface, the outer surface of humerus braiding section 1 are run through in epiphysis hole 3;
The lower end of humerus braiding section 1 connects the upper end of tendon free-fiber section 2;
The bottom of tendon free-fiber section 2 is provided with tendon stomidium 4, and tendon stomidium 4 runs through inner surface, the outer surface of tendon free-fiber section 2.Humerus braiding section 1 is rectangle or round rectangle with the integrant shape of tendon free-fiber section 2
Preferably, epiphysis hole 3 is have draught line A, and tendon stomidium 4 is have draught line B.
Preferably, humerus braiding section 1 adopts the network structure of fibrage.Such as, the braided material of humerus braiding section 1 can adopt PET, ultra-high molecular weight polyethylene, nylon material to form.
Preferably, epiphysis hole 3 is screw hole, and tendon stomidium 4 is hole of threading a needle.In change case, epiphysis hole 3 can be band wire holdfast hole or hole of threading a needle.
Preferably, upper face or all surfaces of humerus braiding section 1 are provided with coating I, and lower surface or all surfaces of tendon free-fiber section 2 are provided with coating II, are coated with coating III in humerus braiding section 1 with the junction of tendon free-fiber section 2;
Further, be specially:
-described coating III is the composite coating be made up of the material of coating I and the material of coating II, and wherein, preferably, in described composite coating, the ratio of the material of coating I and the material of coating II is 1:1;
-compared with coating I and/or coating II, described coating III contains different osteogenic growth factors, osteogenic growth medicine, becomes flesh somatomedin or becomes flesh growth medicine;
-described coating I, coating II, coating III are nano coating.
Wherein, coating I can be the material that is made up of any one material following or by the composite of appointing multiple material to form as follows: collagen, gelatin, chitosan, hyaluronic acid, fibroin, Polyethylene Glycol (PEG), polylactic acid (PLA) etc.Coating I can be nanometer silver, nano-titanium, nano aluminium oxide, nanometer calcium triphosphate (TCP), nano-calcium phosphate, sodium carbonate calcium granule etc.The somatomedin of skeletonization can be added in coating I, as: BMP-2, BMP-7, BMP-9; TGF-β 1 (transforminggrowthfactor-β1) etc.
Coating II can be the material that is made up of any one material following or by the composite of appointing multiple material to form as follows: chitosan, glucosan, polylactic acid, hyaluronic acid, polyvinyl alcohol (PVA), etc.Hemoglobin etc. can be added become flesh in coating II, add somatomedin or medicine, as VEGF (VEGF), transforming growth factor-β etc.
As shown in Figure 2, as the preferred technical scheme of Fig. 1, the segmentation Weaving type artificial bone-head for shoulder that a kind of nano coating provided according to this utility model is modified sticking patch of tucking inside the sleeve also comprises: self-deploy support A501, self-deploy support B502, self-deploy support C601, self-deploy support D602;
Humerus braiding section 1 is provided with through hole A7;
Self-deploy support A501 and self-deploy support B502 arranged in a crossed manner, and all through through hole A7;
Self-deploy support A501, self-deploy the upper end of support B502 be all fastenedly connected in humerus braiding section 1 outer surface;
Self-deploy support A501, self-deploy the lower end of support B502 be all fastenedly connected in humerus braiding section 1 inner surface;
Tendon free-fiber section 2 is provided with through hole B8;
Self-deploy support C601 and self-deploy support D602 arranged in a crossed manner, and all through through hole B8;
Self-deploy support C601, self-deploy the lower end of support D602 and be all fastenedly connected outer surface in tendon free-fiber section 2; Self-deploy support C601, self-deploy the upper end of support D602 and be all fastenedly connected inner surface in tendon free-fiber section 2.
Preferably, self-deploy support A501, self-deploy support B502, self-deploy support C601, self-deploy support D602 and be and adopt the strip laminated structure made of memorial alloy or rod-like structure;
Self-deploy support A501, self-deploy the concrete structure of support B502 and be: except top and bottom, the surface that remainder and humerus weave section 1 is separated;
Self-deploy support C601, self-deploy the concrete structure of support D602 and be: except top and bottom, the surface of remainder and tendon free-fiber section 2 is separated.
As shown in Figure 4, by self-deploying support A501, self-deploying support B502, self-deploy support C601, self-deploying support D602, the segmentation Weaving type artificial bone-head for shoulder that described nano coating is modified sticking patch of tucking inside the sleeve can be changed between rounding state and deployed condition.Refer to the arrow on the right of paper in Fig. 4, the segmentation Weaving type artificial bone-head for shoulder that described nano coating is modified sticking patch of tucking inside the sleeve is gradually compressed highly from complete deployed condition (i.e. naturalness), then carry out curling to the segmentation Weaving type artificial bone-head for shoulder sticking patch of tucking inside the sleeve that nano coating is modified in the width direction, the segmentation Weaving type artificial bone-head for shoulder that described nano coating is modified sticking patch of tucking inside the sleeve can be stuffed into conduit, to be sent to affected area along conduit, when after arrival affected area, support A501 is self-deployed by what be made up of memorial alloy, self-deploy support B502, self-deploy support C601, self-deploy support D602 to self-deploy from the state of batching, then pull the tuck inside the sleeve height of sticking patch of the segmentation Weaving type artificial bone-head for shoulder that described nano coating is modified by doctor and become large until deployed condition completely.
As shown in Figure 3, preferably, the segmentation Weaving type artificial bone-head for shoulder that described nano coating is modified sticking patch of tucking inside the sleeve can be stuffed into conduit and also comprises: external protection 901, inner protective layer 902;
External protection 901, inner protective layer 902 are formed by a pieces of fabric 1001 and a free-fiber sheet 1002;
The pieces of fabric 1001 of external protection 901 covers the outer surface of humerus braiding section 1, and is positioned at the outside self-deploying support A501, self-deploy support B502;
The free-fiber sheet 1002 of external protection 901 covers the outer surface of tendon free-fiber section 2, and is positioned at the outside self-deploying support C601, self-deploy support D602;
The pieces of fabric 1001 of inner protective layer 902 covers the inner surface of humerus braiding section 1, and it is positioned at the inner side self-deploying support A501, self-deploy support B502;
The free-fiber sheet 1002 of inner protective layer 902 covers the inner surface of tendon free-fiber section 2, and is positioned at the inner side self-deploying support C601, self-deploy support D602.
As shown in Figure 5, the joint boundary line D indentation that the upper end that the lower end of humerus braiding section 1 connects described tendon free-fiber section 2 described in change case embodiment illustrated in fig. 1 is formed.The lower edge indentation of humerus braiding section 1, the zigzag that the upper end-face edge of tendon free-fiber section 2 matches in the lower edge weaving section 1 with humerus.
Preferably, described humerus braiding section 1 and the junction of tendon free-fiber section 2, refer to: the entirety be made up of humerus braiding section 1, tendon free-fiber section 2 includes one section of described joint boundary line D in the height direction.
Above specific embodiment of the utility model is described.It is to be appreciated that this utility model is not limited to above-mentioned particular implementation, those skilled in the art can make a variety of changes within the scope of the claims or revise, and this does not affect flesh and blood of the present utility model.When not conflicting, the feature in the embodiment of the application and embodiment can combine arbitrarily mutually.
Claims (10)
1. the segmentation Weaving type artificial bone-head for shoulder that nano coating is modified tucks inside the sleeve a sticking patch, it is characterized in that, comprising: humerus braiding section (1), tendon free-fiber section (2);
The top of humerus braiding section (1) is provided with epiphysis hole (3), and epiphysis hole (3) run through inner surface, the outer surface of humerus braiding section (1);
The lower end of humerus braiding section (1) connects the upper end of tendon free-fiber section (2);
The bottom of tendon free-fiber section (2) is provided with tendon stomidium (4), and tendon stomidium (4) runs through inner surface, the outer surface of tendon free-fiber section (2);
Humerus braiding section (1) and tendon free-fiber section (2) integrant shape are rectangle or round rectangle.
2. the segmentation Weaving type artificial bone-head for shoulder that nano coating according to claim 1 is modified tucks inside the sleeve sticking patch, and it is characterized in that, epiphysis hole (3) are have draught line A, and tendon stomidium (4) is have draught line B.
3. the segmentation Weaving type artificial bone-head for shoulder that nano coating according to claim 1 is modified tucks inside the sleeve sticking patch, and it is characterized in that, humerus braiding section (1) adopts the network structure of fibrage.
4. the segmentation Weaving type artificial bone-head for shoulder that nano coating according to claim 1 is modified tucks inside the sleeve sticking patch, and it is characterized in that, epiphysis hole (3) and tendon stomidium (4) adopt any one mode as follows:
-epiphysis hole (3) is screw hole, and tendon stomidium (4) is hole of threading a needle;
-epiphysis hole (3) for band wire holdfast hole, tendon stomidium (4) be hole of threading a needle;
-epiphysis hole (3) is hole of threading a needle, and tendon stomidium (4) is hole of threading a needle.
5. the segmentation Weaving type artificial bone-head for shoulder that nano coating according to claim 1 is modified tucks inside the sleeve sticking patch, it is characterized in that, upper face or all surfaces of humerus braiding section (1) are provided with coating I, lower surface or all surfaces of tendon free-fiber section (2) are provided with coating II, are coated with coating III at humerus braiding section (1) and the junction of tendon free-fiber section (2);
Further, be specially:
-described coating III is the composite coating be made up of the material of coating I and the material of coating II;
-compared with coating I and/or coating II, described coating III contains different osteogenic growth factors, osteogenic growth medicine, becomes flesh somatomedin or becomes flesh growth medicine;
-described coating I, coating II, coating III are nano coating.
6. the segmentation Weaving type artificial bone-head for shoulder that nano coating is modified according to claim 1 or 5 tucks inside the sleeve sticking patch, it is characterized in that, the joint boundary line D indentation that the upper end that the lower end that described humerus weaves section (1) connects described tendon free-fiber section (2) is formed.
7. the segmentation Weaving type artificial bone-head for shoulder that nano coating according to claim 6 is modified tucks inside the sleeve sticking patch, it is characterized in that, described humerus braiding section (1) and the junction of tendon free-fiber section (2), refer to: the entirety be made up of the humerus section of braiding (1), tendon free-fiber section (2) includes one section of described joint boundary line D in the height direction.
8. the segmentation Weaving type artificial bone-head for shoulder that nano coating according to claim 1 is modified tucks inside the sleeve sticking patch, it is characterized in that, also comprise: self-deploy support A (501), self-deploy support B (502), self-deploy support C (601), self-deploy support D (602);
Humerus braiding section (1) is provided with through hole A (7);
Self-deploy support A (501) and self-deploy support B (502) arranged in a crossed manner, and all through through hole A (7);
Self-deploy support A (501), self-deploy the upper end of support B (502) be all fastenedly connected in humerus braiding section (1) outer surface; Self-deploy support A (501), self-deploy the lower end of support B (502) be all fastenedly connected in humerus braiding section (1) inner surface;
Tendon free-fiber section (2) is provided with through hole B (8);
Self-deploy support C (601) and self-deploy support D (602) arranged in a crossed manner, and all through through hole B (8);
Self-deploy support C (601), self-deploy the lower end of support D (602) and be all fastenedly connected outer surface in tendon free-fiber section (2); Self-deploy support C (601), self-deploy the upper end of support D (602) and be all fastenedly connected inner surface in tendon free-fiber section (2).
9. the segmentation Weaving type artificial bone-head for shoulder that nano coating according to claim 8 is modified tucks inside the sleeve sticking patch, it is characterized in that, self-deploy support A (501), self-deploy support B (502), self-deploy support C (601), self-deploy support D (602) and be and adopt the strip laminated structure made of memorial alloy or rod-like structure;
Self-deploy support A (501), self-deploy the concrete structure of support B (502) and be: except top and bottom, the surface that remainder and humerus weave section (1) is separated;
Self-deploy support C (601), self-deploy the concrete structure of support D (602) and be: except top and bottom, the surface of remainder and tendon free-fiber section (2) is separated.
10. the segmentation Weaving type artificial bone-head for shoulder that nano coating according to claim 9 is modified tucks inside the sleeve sticking patch, it is characterized in that, also comprises: external protection (901), inner protective layer (902);
External protection (901), inner protective layer (902) are formed by a pieces of fabric (1001) and a free-fiber sheet (1002);
The pieces of fabric (1001) of external protection (901) covers the outer surface of humerus braiding section (1), and is positioned at the outside self-deploying support A (501), self-deploy support B (502);
The free-fiber sheet (1002) of external protection (901) covers the outer surface of tendon free-fiber section (2), and is positioned at the outside self-deploying support C (601), self-deploy support D (602);
The pieces of fabric (1001) of inner protective layer (902) covers the inner surface of humerus braiding section (1), and it is positioned at the inner side self-deploying support A (501), self-deploy support B (502);
The free-fiber sheet (1002) of inner protective layer (902) covers the inner surface of tendon free-fiber section (2), and is positioned at the inner side self-deploying support C (601), self-deploy support D (602).
Priority Applications (1)
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CN201520721689.7U CN204995611U (en) | 2015-09-17 | 2015-09-17 | Artifical shoulder sleeve patch of type is woven in segmentation that nanometer coating was decoratied |
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CN201520721689.7U CN204995611U (en) | 2015-09-17 | 2015-09-17 | Artifical shoulder sleeve patch of type is woven in segmentation that nanometer coating was decoratied |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105125317A (en) * | 2015-09-17 | 2015-12-09 | 复旦大学附属华山医院 | Segmented nano coating modified artificial rotator cuff patch |
CN114404670A (en) * | 2022-01-19 | 2022-04-29 | 福州市第二医院(福建省福州中西医结合医院、福州市职业病医院) | Rotator cuff patch based on polyethylene and collagen coating and preparation method thereof |
-
2015
- 2015-09-17 CN CN201520721689.7U patent/CN204995611U/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105125317A (en) * | 2015-09-17 | 2015-12-09 | 复旦大学附属华山医院 | Segmented nano coating modified artificial rotator cuff patch |
CN114404670A (en) * | 2022-01-19 | 2022-04-29 | 福州市第二医院(福建省福州中西医结合医院、福州市职业病医院) | Rotator cuff patch based on polyethylene and collagen coating and preparation method thereof |
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Granted publication date: 20160127 Termination date: 20200917 |