CN204939454U - Used heat reutilization system in a kind of hyaluronic acid production technique - Google Patents

Used heat reutilization system in a kind of hyaluronic acid production technique Download PDF

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Publication number
CN204939454U
CN204939454U CN201520670477.0U CN201520670477U CN204939454U CN 204939454 U CN204939454 U CN 204939454U CN 201520670477 U CN201520670477 U CN 201520670477U CN 204939454 U CN204939454 U CN 204939454U
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water
hyaluronic acid
tank
used heat
acid production
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韩秀云
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AWA BIOTECH BINZHOU Co Ltd
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AWA BIOTECH BINZHOU Co Ltd
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Abstract

The utility model relates to the used heat reutilization system in a kind of hyaluronic acid production technique, comprise fermentor tank, cold water tank, rectifying tower, hot tub, water supply tank and Administrative Area, top, the bottom of described fermentor tank arrange steam inlet, vapour outlet respectively, described vapour outlet connects water supply tank by steam conveying pipe, described water supply tank is connected with hot tub respectively by two delivery pipelines, and described hot tub connects hot-water cylinder and Administrative Area respectively by heating conveying tube road.The beneficial effects of the utility model are, in this used heat reutilization system, the waste water for fermentor tank and rectifying tower heat exchange can be made to be utilized effectively, and Waste Heat Reuse rate is greatly improved, energy efficient, reduce plant area's heat demand, save energy.

Description

Used heat reutilization system in a kind of hyaluronic acid production technique
Technical field
The utility model relates to hyaluronic acid production technical field, particularly relates to the used heat reutilization system in a kind of hyaluronic acid production technique.
Background technology
Hyaluronic acid (Hyaluronicacid, HA) has another name called hyaluronic acid or Hyaluronic Acid, is the necessary mucopolysaccharide of a kind of Human Physiology, is extensively present in the various tissues of animal and human body.In different tissues, the physiological action of HA is different, as being mainly lubrication in knuckle synovia; Mainly permeability is regulated in vessel wall; Main manifestations is water retention in skin.Based on HA high viscosity, oilness, water-retentivity, good biocompatibility and special physiological property etc. thereof, it has been widely used at field of medicaments, and the application at present in the world in orthopaedics, ophthalmology, surgery, wound, sustained release preparation, induction targetable drug carriers, oncotherapy, dermal filler etc. all achieves larger progress.
It is also a kind of ordinary method that current employing fermentable produces hyaluronic acid, and it compensate for traditional cockscomb extraction method and produces hyaluronic deficiency.Fermentable produces hyaluronic acid, has greatly widened the source of HA, has promoted the investigation and application of HA.
Microbe fermentation method produces the principle of HA: streptococcus is in facultative anaerobe, in the zymotechnique of HA, according to HA biosynthesizing route, the glucose metabolism of aerobic fermentation can produce more ATP, be conducive to 5 '-uridine triphosphate trisodium (UTP) to generate, and UTP is extract, i.e. UDP-glucuronic acid and the necessary material of UDP-N-n acetylglucosamine n before two activation of synthesis HA, therefore from the angle of metabolic regulation, aerobic fermentation is conducive to the synthesis of HA.
Synthesis technique is: inclined-plane seed-shake-flask seed-inoculation-fermentation culture-feed supplement-put tank-fermented liquid (adding ethanol crude extract)-crude extract (add flocculating aids, gac, adjust PH)-filtration (removal impurity)-filtrate (alcohol settling)-throw out (dehydrating)-finished product hyaluronic acid.
In fermenting process, need to carry out sterilizing to fermentor tank, be first heated to 95 degree of excluding airs; Continue to be heated to 121-125 degree and keep sterilizing certain hour.In traditional zymotic process, be not utilized effectively for the hot steam heating fermentor tank, cause great energy dissipation.
For the hot water after the heat exchange of fermentor tank, rectifying tower, be not effectively utilized after the heat exchange and drain, still do not waste resource, also add the burden of Sewage treatment systems.
Summary of the invention
Technical problem to be solved in the utility model is, used heat reutilization system in a kind of hyaluronic acid production technique is provided, in this system, makes the waste water for fermentor tank, rectifying tower heat exchange obtain recycle, Waste Heat Reuse rate is greatly improved, energy efficient.
For achieving the above object, the utility model adopts following technical proposals:
Used heat reutilization system in a kind of hyaluronic acid production technique, comprise fermentor tank, cold water tank, rectifying tower, hot tub, water supply tank and Administrative Area, top, the bottom of described fermentor tank arrange steam inlet, vapour outlet respectively, described vapour outlet connects water supply tank by steam conveying pipe, described water supply tank is connected with hot tub respectively by two delivery pipelines, and described hot tub connects hot-water cylinder and Administrative Area respectively by heating conveying tube road.
Especially, described hot tub also connects rectifying tower by described steam conveying pipe.
Especially, described fermenter base is provided with cooling water inlet, and described cooling water inlet connects cold water tank by cold water transport pipe, and described cold water transport pipe is provided with cold water small pump.
Especially, described water supply tank also connects described hot tub by moisturizing pipeline.
Especially, the described heating conveying tube road connecting described hot-water cylinder and described hot tub is provided with radiator heat water pump.
Especially, delivery pipeline described in one of them arranges hot water circulating pump, delivery pipeline described in another arranges water compensating valve.
Especially, zone of heating is installed in described fermentor tank outside, and agitator is installed in described fermentor tank inside.
The beneficial effects of the utility model are:
1, for heating the used heat of fermentor tank, flow to water supply tank through steam conveying pipe, the water in heating water supply tank, is used for heating supply system by water supply tank, effectively utilizes the used heat of fermenting process, energy efficient.
2, for heating the used heat of rectifying tower, directly flowing to hot tub through steam conveying pipe, being connected to heating supply system, for the heat supply of plant area's Administrative Area, energy efficient.
3, for heating the used heat of fermentor tank and heating rectifying tower, being transported to boiler house by the road, for the moisturizing of boiler, saving the energy consumption of combustion gas.
Accompanying drawing explanation
Fig. 1 is the utility model one-piece construction schematic diagram.
Wherein, 1, fermentor tank; 2, agitator; 3, zone of heating; 4, steam inlet; 5, vapour outlet; 6, cold water tank; 7, rectifying tower; 8, hot tub; 9, hot-water cylinder; 10, water supply tank; 11, Administrative Area; 12, cold water small pump; 13, radiator heat water pump; 14, hot water circulating pump; 15, water compensating valve; 16, cooling water inlet; 17, delivery pipeline; 18, heating conveying tube road; 19, steam conveying pipe; 20, cold water transport pipe.
Embodiment
In order to the technical characterstic of this programme can be clearly described, below in conjunction with drawings and Examples, the utility model is further described.
Used heat reutilization system in a kind of hyaluronic acid production technique, as shown in Figure 1, comprise fermentor tank 1, cold water tank 6, rectifying tower 7, hot tub 8, water supply tank 10 and Administrative Area 11, the top of described fermentor tank 1, bottom arrange steam inlet 4, vapour outlet 5 respectively, described vapour outlet 5 connects water supply tank 10 by steam conveying pipe 19, described water supply tank 10 is connected with hot tub 8 respectively by two delivery pipelines 17, and described hot tub 8 connects hot-water cylinder 9 and Administrative Area 11 respectively by heating conveying tube road 18.
Described hot tub 8 also connects rectifying tower 7 by described steam conveying pipe 19.
Be provided with cooling water inlet 16 bottom described fermentor tank 1, described cooling water inlet 16 connects cold water tank 6 by cold water transport pipe 20, and described cold water transport pipe 20 is provided with cold water small pump 12.
Described water supply tank 10 also connects described hot tub 8 by moisturizing pipeline.
Connect on described hot-water cylinder 9 and the described heating conveying tube road 18 of described hot tub 8 and be provided with radiator heat water pump 13.
Zone of heating 3 is installed in described fermentor tank outside, and agitator is installed in described fermentor tank inside.
Delivery pipeline 17 described in one of them is arranged hot water circulating pump 14, delivery pipeline 17 described in another is arranged water compensating valve 15.
Hot steam is for after heating fermentor tank 1, and the vapour outlet 5 through fermentor tank 1 top is transported to water supply tank 10 along steam conveying pipe 19, and for heating the water in water supply tank 10, the used heat in rectifying tower 7 is transported to heat hot water in hot tub 8 through steam conveying pipe 19.
In the utility model, the used heat of fermentor tank 1, rectifying tower 7 flows to hot tub 8 through steam conveying pipe 19, and then is communicated with heating installation heating system, used heat is utilized effectively, save energy.
The utility model can pass through existing techniques in realizing without the technical characteristic described, and does not repeat them here.Certainly; above-mentioned explanation is not to restriction of the present utility model; the utility model is also not limited only to above-mentioned citing, and the change of the art those of ordinary skill done by essential scope of the present utility model, remodeling, interpolation or replacing, also should belong to protection domain of the present utility model.

Claims (7)

1. the used heat reutilization system in a hyaluronic acid production technique, comprise fermentor tank, cold water tank, rectifying tower, hot tub, water supply tank and Administrative Area, it is characterized in that, top, the bottom of described fermentor tank arrange steam inlet, vapour outlet respectively, described vapour outlet connects water supply tank by steam conveying pipe, described water supply tank is connected with hot tub respectively by two delivery pipelines, and described hot tub connects hot-water cylinder and Administrative Area respectively by heating conveying tube road.
2. the used heat reutilization system in a kind of hyaluronic acid production technique as claimed in claim 1, is characterized in that, described hot tub also connects rectifying tower by described steam conveying pipe.
3. the used heat reutilization system in a kind of hyaluronic acid production technique as claimed in claim 1, it is characterized in that, described fermenter base is provided with cooling water inlet, and described cooling water inlet connects cold water tank by cold water transport pipe, and described cold water transport pipe is provided with cold water small pump.
4. the used heat reutilization system in a kind of hyaluronic acid production technique as claimed in claim 3, it is characterized in that, described water supply tank also connects described hot tub by moisturizing pipeline.
5. the used heat reutilization system in a kind of hyaluronic acid production technique as claimed in claim 1, is characterized in that, the described heating conveying tube road connecting described hot-water cylinder and described hot tub is provided with radiator heat water pump.
6. the used heat reutilization system in a kind of hyaluronic acid production technique as claimed in claim 1, is characterized in that, delivery pipeline described in one of them arranges hot water circulating pump, delivery pipeline described in another arranges water compensating valve.
7. the used heat reutilization system in a kind of hyaluronic acid production technique as described in claim 1 or 3, is characterized in that, zone of heating is installed in described fermentor tank outside, and agitator is installed in described fermentor tank inside.
CN201520670477.0U 2015-09-01 2015-09-01 Used heat reutilization system in a kind of hyaluronic acid production technique Active CN204939454U (en)

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CN201520670477.0U CN204939454U (en) 2015-09-01 2015-09-01 Used heat reutilization system in a kind of hyaluronic acid production technique

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CN204939454U true CN204939454U (en) 2016-01-06

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108609790A (en) * 2018-05-07 2018-10-02 山东焦点生物科技股份有限公司 A kind of water circulation system of Sodium Hyaluronate clean manufacturing

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108609790A (en) * 2018-05-07 2018-10-02 山东焦点生物科技股份有限公司 A kind of water circulation system of Sodium Hyaluronate clean manufacturing

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