CN204909824U - Antibiotic applying ointment or plaster of medical restoration that contains EGF - Google Patents

Antibiotic applying ointment or plaster of medical restoration that contains EGF Download PDF

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Publication number
CN204909824U
CN204909824U CN201520034664.XU CN201520034664U CN204909824U CN 204909824 U CN204909824 U CN 204909824U CN 201520034664 U CN201520034664 U CN 201520034664U CN 204909824 U CN204909824 U CN 204909824U
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China
Prior art keywords
layer
plaster
medical
antibiotic
containing egf
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201520034664.XU
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Chinese (zh)
Inventor
谢建飞
周建大
丁四清
秦春香
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Third Xiangya Hospital of Central South University
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Third Xiangya Hospital of Central South University
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Priority to CN201520034664.XU priority Critical patent/CN204909824U/en
Application granted granted Critical
Publication of CN204909824U publication Critical patent/CN204909824U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model relates to a novel medical applying ointment or plaster, concretely relates to antibiotic applying ointment or plaster of medical restoration of containing EGF. It comprises stratum basale, dressing layer and peel ply, makes up in proper order extremely down on the follow. Layer and antibiotic layer are restoreed including two -layer from top to bottom promptly in the dressing layer. Restoreing the layer and being provided with epidermal growth factor(EGF) (EGF), antibiotic layer is provided with nanometer silver ion. Antibiotic applying ointment or plaster of medical restoration that contains EGF, have concurrently the tissue restore with the antibiosis and antiphlogosis function, can effectively promote epithelial tissue's wound restoration, prevent that the skin scar of the puncture of sound arteries and veins, traumatism, treatment, postsurgical from forming, simultaneously, go on effectively antibioticly to the surface of a wound, improved patient's comfort, also class provide good skin condition for puncture once more.

Description

A kind of medical reparation containing EGF is antibacterial applies ointment or plaster
Technical field
This utility model relates to a kind of new medical and applies ointment or plaster, and a kind of medical reparation containing EGF is antibacterial specifically applies ointment or plaster.
Background technology
The reparation of surgical wound, treatment, postoperative wound is disposed not ideal enough.Clinically, generally use absorbent cotton or gauze wrapping and cover outer wound and postoperative wound, but in the process of changing dressings, easily tearing incrustation wound, increase pain scores, adding the misery of patient, delay the healing of wound, even caused or increased the weight of the formation of cicatrix of skin.
Artery and vein puncture place efficient skin care is unsatisfactory.Along with the professional development of venous transfusion nursing, domestic large hospital progressively creates without draw point ward, and more inpatient selects remaining needle to carry out infusion treatment, but the puncture place skin nursing after treatment terminates gets the brush-off.
The problem of hemodialysis patients puncture place skin is particularly outstanding.Internal fistula is the lane-wise that most patients with renal failure selects chronic hemodialysis, due to for a long time, artery and vein puncture frequently, clinically, such hemodialysis patients skin is very bad, if can not obtain disposing in time, effectively, the skin penetrating state of patient will be forced into a vicious cycle.Thus, start a kind of can effectively solve epithelial tissue repair the convenient of problem apply ointment or plaster, be the sincere Gospel of clinical blood dialysis patient.
Tradition is applied ointment or plaster to design and be there are some defects.Medical application, adopts nonwoven cloth material more, is infiltrated on non-woven fabrics, is affixed on affected part by medicine physics, percutaneous absorption, plays drug effect.But there is feature that is volatile, that easily come off, easily pollute more.
Current; the medical portable peel ply of applying ointment or plaster or so-called protective layer opening select the centre position of applying ointment or plaster on the market, although the thin layer of two-piece type has lap, because opening is in dressing layer position; easily touch dressing layer, wound location during use, cause secondary pollution.
Current reparation product category of applying ointment or plaster is more, have and possess antiphlogistic antibacterial, stop blooding antipruritic, promote the performance of repairing, exist poor efficiency, middle effect, efficient point.But in use, occurred the reactions such as histiocyte toxicity, skin histology allergy, the biological safety that tool is not good, has a strong impact on the use and popularization of applying ointment or plaster.
Summary of the invention
For overcoming the technological deficiency of existing design concept and medical defect, the object of this invention is to provide that a kind of medical reparation containing EGF is antibacterial applies ointment or plaster, the medical application that a kind of cost is lower, have tissue repair and anti-inflammation function concurrently can be provided for inpatient or out-patient, can prevent artery and vein puncture, wound, treatment, Post operation skin scar from being formed simultaneously, improving the comfort of patient, is also the skin condition that puncture again waits creation good.
Described a kind of medical reparation containing EGF is antibacterial applies ointment or plaster, and comprises basal layer (1), dressing layer (2) and peel ply (3), combines successively from top to bottom.Described dressing layer comprises two-layer up and down, comprises repair layer and antibiotic layer.
Described repair layer, adopts safe formula, specific as follows:
Epidermal growth factor (EpidermalGrowthFactor, EGF) 0.1 ~ 3%
Vitamin A 0.02 ~ 2%
Vitamin E 0.02 ~ 3%
Gelatin 5 ~ 25%
Cupu oil 0.2 ~ 2%
Glycerol 2 ~ 5%
Hyaluronic acid 1 ~ 3%
Citric acid 0.5 ~ 4%
Deionized water adds to 100%
Described EGF, is a kind of small molecular protein be extensively present in human skin cell, is mainly distributed in the body fluid such as blood, saliva.It can promote the division of Epithelial cell, accelerate cell metabolism, thus can promote the renewal reparation of skin, the full state of elasticity of maintenance skin.
Described repair layer, according to concrete formula, is dissolved in deionized water by VitAVitE, gelatin, cupu oil, glycerol, hyaluronic acid, citric acid, be heated to 40 ~ 70 DEG C, obtain clear solution, after being cooled to 5 ~ 21 DEG C, add EGF, hybrid process film forming.Membranaceous repair layer like this contributes to applying ointment or plaster more docile in wound.In addition, Nanometer silver dressing layer can play moisture-keeping function, prevents the volatilization of EGF, contributes to the drug effect of realizing ideal.
Described antibiotic layer, adopts nano-silver active carbon fibrous layer, can play wide spectrum, brute force, lasting antibacterial and anti-inflammation functions, is conducive to reducing dressing change frequency.In addition, the absorption advantage of activated carbon fiber layers, effectively can promote drug effect, process sepage, and improves the subjective comfortable feeling of patient.
Described basal layer, adopts micro-porous permeable, antianaphylactic non-woven fabrics medical adhesive tape, has the feature of few stimulation, easily stripping, easily observation, not trace, can prevent the pain scores of tearing incrustation wound in the process of changing dressings, increasing patient.
Described peel ply, be the one in thermoplastic polyurethane film or polyethylene film, cost is low, disposal of easily sterilizing.
Described peel ply, its thin film is divided into long thin film and short thin film.Long thin film from left to right, covers 3/5 of the left side basal layer of applying ointment or plaster, whole dressing layer and right side basal layer; Short thin film from right to left, covers 4/5 of right side basal layer.The lap of such two-piece type thin layer, on right side of applying ointment or plaster, because opening avoids middle dressing layer, not easily touches dressing layer, wound location during use, has avoided the possibility of wound secondary pollution.
The described medical reparation containing EGF is antibacterial applies ointment or plaster, and global shape is rectangle or square, and arc finishing is protectively carried out in four corners, protects skin as much as possible and safeguard the subjective feeling of patient from little details.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model.
Detailed description of the invention
See accompanying drawing 1, medical reparation of the present utility model is antibacterial applies ointment or plaster.Comprise basal layer 1, dressing layer 2 and peel ply 3, combine successively from top to bottom.
Described repair layer, according to proprietary formula, is dissolved in deionized water by VitAVitE, gelatin, cupu oil, glycerol, hyaluronic acid, citric acid, is heated to 40 ~ 70 DEG C, obtains clear solution, add EGF after being cooled to 5 ~ 21 DEG C, hybrid process film forming.
Described dressing layer, repair layer is provided with epidermal growth factor(EGF) (EGF), adopts hybrid process film forming; Antibiotic layer is provided with nano-silver ionic, adopts physics to be infiltrated on NACF.Repair layer covers on antibiotic layer, has ensured the drug effect of EGF layer, meets the reparation concept of " wet union ".
Described peel ply, during use, 1/2 of the short thin film of tear initiation peel ply, tear long thin film 1/3 again, contact gently from right side and then cover wound, after removing peel ply, apply ointment or plaster so that thumb Zhi Fucong center is floating towards periphery, adhesion wound, is convenient to loosen, and avoids secondary pollution and the secondary insult of wound.
Described embodiment is only clearly demonstrate the citing that this utility model does, and and non-invention to the restriction of embodiment.For the those of ordinary skill in described field, other multi-form change or variations can also be made on the basis of the above description.And thus the apparent change of amplifying out or variation, be still within protection domain of the present utility model.。

Claims (9)

1. the medical reparation containing EGF is antibacterial applies ointment or plaster, and it is characterized in that: be overallly made up of basal layer (1), dressing layer (2) and peel ply (3), and combine successively from top to bottom, described dressing layer comprises two-layer up and down, comprises repair layer and antibiotic layer.
2. a kind of medical reparation containing EGF according to claim 1 is antibacterial applies ointment or plaster, and it is characterized in that: repair layer contains epidermal growth factor (EpidermalGrowthFactor, EGF).
3. a kind of medical reparation containing EGF according to claim 2 is antibacterial applies ointment or plaster, and it is characterized in that: by its ingredient processing film forming.
4. a kind of medical reparation containing EGF according to claim 1 is antibacterial applies ointment or plaster, and it is characterized in that: antibiotic layer is the nano-silver active carbon fibrous layer with anti-inflammation.
5. a kind of medical reparation containing EGF according to claim 1 is antibacterial applies ointment or plaster, and it is characterized in that: basal layer is the transparent non-woven fabrics medical adhesive tape of micro-porous permeable.
6. a kind of medical reparation containing EGF according to claim 1 is antibacterial applies ointment or plaster, and it is characterized in that: peel ply is the one in thermoplastic polyurethane film or polyethylene film.
7. a kind of medical reparation containing EGF according to claim 6 is antibacterial applies ointment or plaster, it is characterized in that: the thin film of peel ply is divided into long thin film and short thin film, long thin film from left to right, cover 3/5 of the left side basal layer of applying ointment or plaster, whole dressing layer and right side basal layer, short thin film from right to left, covers 4/5 of right side basal layer.
8. a kind of medical reparation containing EGF according to claim 1 is antibacterial applies ointment or plaster, and it is characterized in that: its gross thickness is 0.2 ~ 0.7cm.
9. a kind of medical reparation containing EGF according to claim 1 is antibacterial applies ointment or plaster, and it is characterized in that: global shape is rectangle or square, arc finishing is protectively carried out in four corners.
CN201520034664.XU 2015-01-19 2015-01-19 Antibiotic applying ointment or plaster of medical restoration that contains EGF Expired - Fee Related CN204909824U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201520034664.XU CN204909824U (en) 2015-01-19 2015-01-19 Antibiotic applying ointment or plaster of medical restoration that contains EGF

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201520034664.XU CN204909824U (en) 2015-01-19 2015-01-19 Antibiotic applying ointment or plaster of medical restoration that contains EGF

Publications (1)

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CN204909824U true CN204909824U (en) 2015-12-30

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111317855A (en) * 2020-02-27 2020-06-23 温州医科大学 Three-dimensional composite spongy structure body for promoting diabetic ulcer wound healing and method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111317855A (en) * 2020-02-27 2020-06-23 温州医科大学 Three-dimensional composite spongy structure body for promoting diabetic ulcer wound healing and method
CN111317855B (en) * 2020-02-27 2021-02-26 温州医科大学 Three-dimensional composite spongy structure body for promoting diabetic ulcer wound healing and method

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20151230

Termination date: 20170119