CN204857028U - Nucleic acid structure model - Google Patents
Nucleic acid structure model Download PDFInfo
- Publication number
- CN204857028U CN204857028U CN201520610029.1U CN201520610029U CN204857028U CN 204857028 U CN204857028 U CN 204857028U CN 201520610029 U CN201520610029 U CN 201520610029U CN 204857028 U CN204857028 U CN 204857028U
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- CN
- China
- Prior art keywords
- model
- nylon connecting
- nucleic acid
- connecting portion
- phosphoric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 150000007523 nucleic acids Chemical group 0.000 title claims abstract description 38
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims abstract description 76
- 239000004677 Nylon Substances 0.000 claims abstract description 57
- 229920001778 nylon Polymers 0.000 claims abstract description 57
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims abstract description 37
- 150000002972 pentoses Chemical class 0.000 claims abstract description 20
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 claims description 17
- 125000004432 carbon atom Chemical group C* 0.000 claims description 15
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 claims description 10
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 claims description 10
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 claims description 10
- 229930024421 Adenine Natural products 0.000 claims description 5
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 claims description 5
- 229960000643 adenine Drugs 0.000 claims description 5
- 229940113082 thymine Drugs 0.000 claims description 5
- 229940035893 uracil Drugs 0.000 claims description 5
- 238000004026 adhesive bonding Methods 0.000 claims description 3
- 108091032973 (ribonucleotides)n+m Chemical group 0.000 abstract description 11
- 108091028664 Ribonucleotide Proteins 0.000 abstract description 8
- 239000002336 ribonucleotide Substances 0.000 abstract description 8
- 125000002652 ribonucleotide group Chemical group 0.000 abstract description 8
- 108020004414 DNA Chemical group 0.000 abstract description 6
- 230000035479 physiological effects, processes and functions Effects 0.000 abstract description 5
- 238000000926 separation method Methods 0.000 abstract description 3
- 238000010276 construction Methods 0.000 description 6
- 229910052739 hydrogen Inorganic materials 0.000 description 6
- 239000001257 hydrogen Substances 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- 238000000034 method Methods 0.000 description 4
- 238000004088 simulation Methods 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 238000010839 reverse transcription Methods 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000002299 complementary DNA Substances 0.000 description 2
- 238000010353 genetic engineering Methods 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- -1 transcribe Proteins 0.000 description 2
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 description 1
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
Landscapes
- Saccharide Compounds (AREA)
Abstract
(B, ) the utility model discloses a nucleic acid structure model, it includes at least one pentose model, at least one phosphoric acid molecular model, at least one phosphoric acid residue model, at least one base model, the pentose model, the phosphoric acid molecular model, phosphoric acid residue model, the nylon connecting portion all have on the base model, the nylon connecting portion include a plurality of plugs that have the head, the space all has between the adjacent plug, can connect each other between two nylon connecting portion with breaking away from, when two nylon connecting portion are connected, the head of plug all inserts on the nylon connecting portion of connecting with it in the space between the plug on every nylon connecting portion. This nucleic acid structure model connects through the nylon connecting portion between each group model, and it is convenient freely to connect with the separation, can use repeatedly. Deoxynucleotide or ribo -nucleotide, DNA, RNA structure can be set up to this nucleic acid structure model, still can simulate various relevant physiology courses among the central dogma, and nature directly perceived is strong. This nucleic acid structure model preparation processing is simple and convenient, not fragile, low cost. (B, )
Description
Technical field
the utility model relates to a kind of nucleic acid structure model, particularly relates to a kind ofly can set up deoxynucleotide, the model of ribonucleotide and DNA, RNA the learning aid of Relevant Physiological Courses in Simulation Center rule.
Background technology
the existing model learning aid can setting up deoxynucleotide, ribonucleotide and DNA, RNA is the syndeton of mallet formula grafting.This syndeton requires very high to the precision of position, Plug Division and endurance, leeway, space as tie point activity is little, then connect tension, repeatedly plug there will be and patch difficulty, leeway, space as tie point activity is excessive, then it is not firm to connect, especially when setting up DNA double screw stereo structure, connect the effect that tension can not reach structural simulation, connect when loosely leaning against torsion and be very easy to throw off.And existing model teaching aid is merely able to simulate the structure setting up deoxynucleotide, ribonucleotide and DNA, RNA, can not realizes the copying of RNA, transcribe, the simulation of the physiology course such as reverse transcription, in the process of teaching and assisted learning, function is limited.
Summary of the invention
in order to solve the problem, the purpose of this utility model is to provide a kind of nucleic acid structure model.
in order to reach above object, the technical solution adopted in the utility model is: nucleic acid structure model, it comprises at least one pentose model, at least one phosphoric acid molecules model, at least one phosphate moiety model, at least one base model, pentose model, phosphoric acid molecules model, phosphate moiety model, base model all has nylon connecting portion, nylon connecting portion comprises multiple plug with head, all there is space between adjacent plug, can mutually connect with departing between two nylon connecting portions, when two nylon connecting portions are connected, on each nylon connecting portion, the head of plug all inserts in the space on the nylon connecting portion that is attached thereto between plug.
further, pentose model comprises the protuberance with the mark of expression No. 5 carbon atoms having expression No. 1 body to the mark of No. 4 carbon atoms and be positioned on this body.
further, pentose model have three nylon connecting portions, two are had to be arranged on the mark of expression No. 1 carbon atom on the corresponding body of on body and position difference and to represent the mark of No. 3 carbon atoms in three nylon connecting portions, another in three nylon connecting portions is arranged on protuberance, and the mark of expression No. 5 carbon atoms on the corresponding protuberance in position.
further, nucleic acid structure also comprises at least one special-shaped phosphoric acid molecules model, and this special-shaped phosphoric acid molecules model also has nylon connecting portion.
further, phosphoric acid molecules model, phosphate moiety model and special-shaped phosphoric acid molecules model are spherical or regular polygon.
further, phosphoric acid molecules model and special-shaped phosphoric acid molecules model all have on a nylon connecting portion, phosphate moiety model there are two nylon connecting portions.
further, base model is rectangular parallelepiped.
further, base model has two nylon connecting portions, two nylon connecting portions are separately positioned on two ends of rectangular parallelepiped.
further, nylon connecting portion 5 is connected on pentose model 1, phosphoric acid molecules model, phosphate moiety model 3, base model 4, special-shaped phosphoric acid molecules model by gluing.
further, base model has five at least, at least five base models comprise at least one first base model representing cytimidine, at least one represent guanine the second base model, at least one represent adenine the 3rd base model, at least one represents the 4th base model of thymine and at least one represents the 5th base model of uracil.
owing to adopting technique scheme, the utility model nucleic acid structure model, connected by nylon connecting portion between each group model, the connection of this nylon connecting portion and convenient separation are freely, the life-span of repeatedly dismantling can reach more than thousand times, meets the requirement of learning aid Reusability.This nucleic acid structure model can set up deoxynucleotide, ribonucleotide and DNA, RNA structure, and especially when constructed dna double helix spatial structure, the junction move place of nylon connecting portion is large, can easily reverse, difficult drop-off.This nucleic acid structure model can also the copying of analog D NA and RNA, transcribe, rna replicon, reverse transcription, shear genes of interest in genetic engineering, be combined with carrier, cDNA construction, simulation gene probe, primer, protein engineering etc.; If be aided with amino acid and polypeptide learning aid, also can the physiology course such as translation process in Simulation Center rule, intuitive is strong, and student fully can start in conjunction with book knowledge and theory, repeatedly practises, and profound understanding uses.This nucleic acid structure modelling processing is simple and convenient, not fragile, with low cost.
Accompanying drawing explanation
accompanying drawing 1 is the structural representation of the utility model nucleic acid structure model, wherein, becomes a deoxynucleotide or ribonucleotide acid profile by this nucleic acid structure model construction;
accompanying drawing 2 is the structural representation of the utility model nucleic acid structure model, wherein, becomes a deoxynucleotide to model by this nucleic acid structure model construction;
the structural representation of accompanying drawing 3 the utility model nucleic acid structure model, wherein, becomes a DNA double chain sheet segment model by this nucleic acid structure model construction;
accompanying drawing 4 is the structural representation of nylon connecting portion in the utility model nucleic acid structure model.
number in the figure is:
1, pentose model; 11, body; 12, protuberance; 2, phosphoric acid molecules model; 3, phosphate moiety model; 4, base model; 5, nylon connecting portion; 51, plug; 52, head; 53, space; 54, substrate; 6, hydrogen bond mark.
Embodiment
below in conjunction with accompanying drawing, preferred embodiment of the present utility model is described in detail, can be easier to make advantages and features of the invention be readily appreciated by one skilled in the art.
as can be seen from the structural representation of accompanying drawing 1 to accompanying drawing 4, present embodiments provide a kind of nucleic acid structure model, it comprises at least one pentose model 1, at least one phosphoric acid molecules model 2, at least one phosphate moiety model 3, at least one base model 4.The shape of pentose model 1, phosphoric acid molecules model 2, phosphate moiety model 3 and base model 4 is different, and preferably, its color is also different.Material is preferably acrylic or plastics.
in the more preferred scheme of one, nucleic acid structure model also comprises at least one special-shaped phosphoric acid molecules model, and this special-shaped phosphoric acid molecules model and phosphoric acid molecules model can be distinguished by different colors or shape or size.Abnormity phosphoric acid molecules model is used at analoging reproduction, the different deoxynucleotide of physiology course tense marker or the ribonucleotide such as transcribes.
in the more preferred embodiment of one, base model 4 has five at least, at least five base models 4 comprise at least one first base model representing cytimidine, at least one represent guanine the second base model, at least one represent adenine the 3rd base model, at least one represents the 4th base model of thymine and at least one represents the 5th base model of uracil.Base model all has mark, distinguishing by marking between the base model representing variety classes base, being respectively C, G, A, T, U.More preferably, each base model also has hydrogen bond mark 6, wherein, the the first base model representing cytimidine and the second base model representing guanine respectively have two hydrogen bond marks 6, the 3rd base model representing adenine, the 4th base model representing thymine and the 5th base model representing uracil respectively have three hydrogen bonds marks 6, according to hydrogen bond mark 6, when corresponding base model is connected, can find out that formed base-pair has several hydrogen bond very intuitively.
pentose model 1, phosphoric acid molecules model 2, phosphate moiety model 3, base model 4, special-shaped phosphoric acid molecules model all has nylon connecting portion 5, in the present embodiment, nylon connecting portion 5 is connected on pentose model 1, phosphoric acid molecules model 2, phosphate moiety model 3, base model 4, special-shaped phosphoric acid molecules model by gluing.
as shown in Figure 4, nylon connecting portion 5 comprises substrate 54, be fixedly installed multiple plugs 51 with head 52 on the substrate 54, between adjacent plug 51, all there is space 53, can mutually connect with departing between two nylon connecting portions 5, when two nylon connecting portions 5 are connected, on each nylon connecting portion 5, the head 52 of plug 51 all inserts in the space 53 on the nylon connecting portion 5 that is attached thereto between plug 51.Above-mentioned glue coating on the substrate 54.
the protuberance 52 that pentose model 1 comprises body 11 and is positioned on this body 11, pentose model 1 represents its No. 1 position to No. 5 carbon atoms with 1-5 marks, wherein represent No. 1-No. 4 carbon atoms be marked on body 11, represent No. 5 carbon atoms be marked on protuberance 12, pentose model 1 have three nylon connecting portions 5, wherein two are separately positioned on body 11, the position of the mark of position difference correspondence markings No. 1 and No. 3 carbon atom, one is arranged on protuberance 12, the position of the mark of corresponding No. 5 carbon atoms in position.Make student connect base respectively to ribodesose or No. 1, ribose, No. 3, No. 5 carbon atoms, form phosphodiester bond, connect phosphoric acid and have clear understanding; In addition to the DNA double chain of construction each other antiparallel strand have strong direct feel.
phosphoric acid molecules model 2 and phosphate moiety model 3 are spherical or regular polygon.Phosphoric acid molecules model 2 and special-shaped phosphoric acid molecules model all has a nylon connecting portion 5.Phosphate moiety model 3 have two nylon connecting portions 5.
base model 4 is rectangular parallelepiped, wherein, the length of the second base model representing guanine and the 3rd base model representing adenine be greater than represent cytimidine the first base model, represent the 4th base model of thymine and represent the 5th base model of uracil.Preferably, the first base model is identical with the length of the 4th base model and the 5th base model; Second base model is identical with the length of the 3rd base model; And the length sum of the first base model and the second base model equals the length sum of the 3rd base model and the 4th base model or equals the length sum of the 3rd base model and the 5th base model.
base model 4 has two nylon connecting portions 5, and two nylon connecting portions 5 are separately positioned on two ends of rectangular parallelepiped.
when constructed dna double helix spatial structure, can also subband (as one side adhesive tape) in addition, reinforce between each part further.
the size of this nucleic acid structure model can be selected according to the needs of practical application.Preferably, when building 10 deoxynucleotides to the DNA double screw stereo structure fragment formed, its diameter (length that namely a deoxynucleotide is right) and length ratio are good with 2.0:3.4.
this nucleic acid structure model, is connected by nylon connecting portion between each group model, and freely, the life-span of repeatedly dismantling can reach more than thousand times for the connection of this nylon connecting portion and convenient separation, meets the requirement of learning aid Reusability.This nucleic acid structure model can set up deoxynucleotide, ribonucleotide, DNA, RNA structure, and especially when constructed dna double helix spatial structure, the junction move place of nylon connecting portion is large, can easily reverse, difficult drop-off.This nucleic acid structure model can also the copying of analog D NA and RNA, transcribe, rna replicon, reverse transcription, shear genes of interest in genetic engineering, be combined with carrier, cDNA construction, simulation gene probe, primer, protein engineering etc.; If be aided with amino acid and polypeptide learning aid, also can the physiology course such as translation process in Simulation Center rule, intuitive is strong, and student fully can start in conjunction with book knowledge and theory, repeatedly practises, and profound understanding uses.This nucleic acid structure modelling processing is simple and convenient, not fragile, with low cost.
above-described embodiment, only for technical conceive of the present utility model and feature are described, its object is to person skilled in the art can be understood content of the present utility model and implement according to this, can not limit protection domain of the present utility model with this.All equivalences done according to the utility model Spirit Essence change or modify, and all should be encompassed within protection domain of the present utility model.
Claims (10)
1. a nucleic acid structure model, it comprises at least one pentose model (1), at least one phosphoric acid molecules model (2), at least one phosphate moiety model (3), at least one base model (4), it is characterized in that: described pentose model (1), phosphoric acid molecules model (2), phosphate moiety model (3), base model (4) all has nylon connecting portion (5), described nylon connecting portion (5) comprises multiple plug (51) with head (52), between adjacent plug (51), all there is space (53), can mutually connect with departing between nylon connecting portion (5) described in two, when two nylon connecting portions (5) are connected, the head (52) of the upper plug (51) of each nylon connecting portion (5) all inserts in the space (53) between the upper plug (51) of the nylon connecting portion (5) be attached thereto.
2. nucleic acid structure model according to claim 1, is characterized in that: described pentose model (1) comprises the protuberance (12) with the mark of expression No. 5 carbon atoms having expression No. 1 body to the mark of No. 4 carbon atoms (11) and be positioned on this body (11).
3. nucleic acid structure model according to claim 2, it is characterized in that: described pentose model (1) has three nylon connecting portions (5), have two to be arranged on described body (11) and position in three described nylon connecting portions (5) distinguish the mark of No. 1, expression on corresponding body (11) and represent the mark of No. 3 carbon atoms, another in three described nylon connecting portions (5) is arranged on described protuberance (12), and the mark of expression No. 5 carbon atoms on the corresponding protuberance (12) in position.
4. nucleic acid structure model according to claim 1, is characterized in that: it also comprises at least one special-shaped phosphoric acid molecules model, and this special-shaped phosphoric acid molecules model also has described nylon connecting portion (5).
5. nucleic acid structure model according to claim 4, is characterized in that: described phosphoric acid molecules model (2), phosphate moiety model (3) and special-shaped phosphoric acid molecules model are spherical or regular polygon.
6. nucleic acid structure model according to claim 5, is characterized in that: described phosphoric acid molecules model (2) and special-shaped phosphoric acid molecules model all have on a nylon connecting portion (5), described phosphate moiety model (3) and has two nylon connecting portions (5).
7. nucleic acid structure model according to claim 1, is characterized in that: described base model (4) is rectangular parallelepiped.
8. nucleic acid structure model according to claim 7, is characterized in that: described base model (4) has two nylon connecting portions (5), and two described nylon connecting portions (5) are separately positioned on two ends of described rectangular parallelepiped.
9. nucleic acid structure model according to claim 1, is characterized in that: described nylon connecting portion (5) is connected on pentose model (1), phosphoric acid molecules model (2), phosphate moiety model (3), base model (4), special-shaped phosphoric acid molecules model by gluing.
10. nucleic acid structure model according to claim 1, it is characterized in that: described base model (4) has five at least, at least five base models (4) comprise at least one first base model representing cytimidine, at least one represent guanine the second base model, at least one represent adenine the 3rd base model, at least one represents the 4th base model of thymine and at least one represents the 5th base model of uracil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520610029.1U CN204857028U (en) | 2015-08-14 | 2015-08-14 | Nucleic acid structure model |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520610029.1U CN204857028U (en) | 2015-08-14 | 2015-08-14 | Nucleic acid structure model |
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| Publication Number | Publication Date |
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| CN204857028U true CN204857028U (en) | 2015-12-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201520610029.1U Expired - Fee Related CN204857028U (en) | 2015-08-14 | 2015-08-14 | Nucleic acid structure model |
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| Country | Link |
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| CN (1) | CN204857028U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106448353A (en) * | 2016-10-18 | 2017-02-22 | 电子科技大学 | Gene engineering demonstration model |
| CN106652707A (en) * | 2017-02-21 | 2017-05-10 | 樊郁兰 | Method and apparatus for simulating DNA secondary structure in middle school biology teaching |
| CN111127988A (en) * | 2020-01-16 | 2020-05-08 | 辽宁科技学院 | Dynamic demonstration instrument for DNA double-spiral structure |
-
2015
- 2015-08-14 CN CN201520610029.1U patent/CN204857028U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106448353A (en) * | 2016-10-18 | 2017-02-22 | 电子科技大学 | Gene engineering demonstration model |
| CN106448353B (en) * | 2016-10-18 | 2023-07-07 | 电子科技大学 | Genetic engineering demonstration model |
| CN106652707A (en) * | 2017-02-21 | 2017-05-10 | 樊郁兰 | Method and apparatus for simulating DNA secondary structure in middle school biology teaching |
| CN111127988A (en) * | 2020-01-16 | 2020-05-08 | 辽宁科技学院 | Dynamic demonstration instrument for DNA double-spiral structure |
| CN111127988B (en) * | 2020-01-16 | 2022-02-25 | 辽宁科技学院 | Dynamic demonstration instrument for DNA double-spiral structure |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151209 |
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| CF01 | Termination of patent right due to non-payment of annual fee |