CN204723097U - A kind of split type speckle examination device - Google Patents

A kind of split type speckle examination device Download PDF

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Publication number
CN204723097U
CN204723097U CN201520181445.4U CN201520181445U CN204723097U CN 204723097 U CN204723097 U CN 204723097U CN 201520181445 U CN201520181445 U CN 201520181445U CN 204723097 U CN204723097 U CN 204723097U
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China
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patch
split type
patch cell
examination device
cell
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Chinese (zh)
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文利平
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Peking Union Medical College Hospital Chinese Academy of Medical Sciences
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Peking Union Medical College Hospital Chinese Academy of Medical Sciences
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Abstract

A kind of split type speckle examination device, comprises patch cell fixing head, patch cell, adhesive tape, and described patch cell is at least one and separated from one another with adhesive tape, and the preset filter paper in the little indoor of patch, described patch cell fixing head offers the hole slightly larger than patch cell.This split type speckle examination device is easy and simple to handle, easy to learn and easy to use; Owing to have employed split type patch cell, patch cell quantity and corresponding reagent can be added as required flexibly; Simultaneously due to the preset filter paper in the little indoor of patch, both can be used for liquid patch reagent, also can with gluey patch reagent, especially easy to the patch reagent operation of solution morphology, simplify operating procedure, save the operating time.

Description

A kind of split type speckle examination device
Technical field
This utility model relates to a kind of test macro, particularly a kind of split type speckle examination device.
Background technology
Contact dermatitis (Contact Dermatitis, CD) the acute and chronic scytitis reaction brought out after to be skin contact with the inorganic matter such as low-molecular-weight organic matter and metal, comprise irritant contact dermatitis (IrritationContact Dermatitis, and allergic contact dermatitis (Allergic Contact Dermatitis, ACD) ICD).Irritant contact dermatitis and immunity have nothing to do, as long as contact has the concentration of irritating chemical substance (such as acid or alkali) and the time is enough, anyly can cause scytitis per capita; Allergic contact dermatitis is caused by immunoreation (IV type allergy).According to foreign literature, the allergic contact dermatitis prevalence that in crowd, various contactant causes is about 5-10%, is one of modal skin allergic disease.The anaphylactogen of allergic contact dermatitis is caused to comprise the household chemicals exposure in daily life and the Occupational Exposure anaphylactogen exposure in working environment.According to the research of Korea S and the U.S., the dermatosis that occupational exposure causes accounts for the 5.5-7.0% of professional relevant disease, and allergic contact dermatitis accounts for 80 ~ 95% of dermatergosis, causes huge disability and economic loss.
In the production that contact allergen is extensively present in us and living environment, as medicated clothing, jewelry, at home articles for use, bath article, production material, instruments of labour, cosmetics, medicine, food and various additives etc.And along with the development in epoch, panoramic new compound comes into the life of people gradually, bring life convenient and comfortable while, also may cause new allergic problem, magazines such as " Contact Dermatitis " all will report the allergic problem that contactant new in a large number causes every year.At present, more than 4000 kind of contact allergen has been determined in the world.The pathogenesis of contact dermatitis is IV type (Delayed onset) allergy, contactant mostly is micromolecular hapten, after being combined with Skin Cell keratoprotein, form complete antigen, after antigen-presenting cell identification and process, form MHC-II molecule-polypeptide-tcr complex, cause specific cell immunoreaction.When after a certain contactant sensitized recipients, occur again general expose again (by intramuscular injection, intravenous injection, oral, internal rectum to or intravaginal administration etc.), these chemical substances are caused to be absorbed by body, can occur " systemic contact dermatitis ", the cinnamic aldehyde such as, contained in food, Peruvian balsam, P-hydroxybenzoic acid or after being polluted by metallic nickel etc., can cause general anaphylaxis contact dermatitis.Nickel, cobalt and chromium etc. are present in various metal implant, may be caused transplant rejection by the individuality of metal sensitization, and causing implantation failure, is also the one of general anaphylaxis contact dermatitis, in recent years by medical profession is paid attention to.
Patch test determines skin contact allergen method safely and reliably, and current patch test is still the goldstandard of diagnosis of allergic contact dermatitis.Except symptomatic treatments such as oral or itching medicine for external use, corticosteroids medicine or immunosuppressant, the key of allergic contact dermatitis treatment is to find the etiological cause of the disease timely and accurately, instructs in which material of patient and contains anaphylactogen, avoid contactant.If disease reason energy early diagnosis, and can strictly avoid contacting again of contactant, more usually better; When Delay in Diagnosis was more than 12 months, dermatitis chronicity, often protracted course of disease, treatment difficulty increases.The importance of early diagnosis as can be seen here.Early diagnosis then depends on the early presentation of disease and carries out the clear and definite anaphylactogen of patch test in time.In addition, the prevention of patch test is significant, can study life and common stimulus object and hapten in producing, and has very important prevention meaning to occupational and Nonoccupational contact dermatitis.
Due to the importance of contact dermatitis, important medical science problem has been developed into the research of contact dermatitis, International Contact Dermatitis seminar (International contact dermatitis researchgroup in 1967, ICDRG) set up, after this have more than 30 country to set up contact dermatitis research association or seminar in the world successively.The speckle examination device that current ICDRG recommends has aluminum (Al-test) speckle to try series and Finn-Chamber (Finn-Chamber) speckle tries series and Qu Taisi (T.R.U.E.) speckle test system, and these products are widely used America and Europe; And all there are the patch test kit of independent development in the states such as Japan for diagnosing ACD.Above-mentioned external patch reagent kit product does not all obtain the clinical practice licence of country of China or local Bureau of Drugs Supervision, though portioned product is applied in the clinical position of fractional unit by registration " medical apparatus and instruments licence ", this way does not also meet the relevant laws and regulations of China's health care.And the speckle examination device of Europe (Sweden) auspicious quick R and the collocation of patch reagent use, do not sell separately its speckle examination device, if the cosmetics that carry of patient or suspect that irritated compound often cannot carry out patch test and detect.Meanwhile, the product outside host country all without country of China and the licence of local Bureau of Drugs Supervision, cannot legally be used in clinical.
In recent years, the domestic patch test kit starting to apply external product gradually of China carries out small-scale observation or survey nature clinical research, but it is few with regard to the localized research of the linguistic term of patch test adhesive tape used and patch reagent, such as No.1 Attached Hospital, Nanjing Medical Univ department of dermatologry once developed Standard screening allergen, but was not converted into ripe patch reagent finished product; Nanjing healthy and free from worry medical development company produce distinguish quick speckle have a try agent and speckle examination device due to adhesive tape material allergic problem, hinder its promotion and application; The patch diagnostic kit that Beijing Yi Da technical equipment factory produces does not obtain the clinical practice licence of country and local Bureau of Drugs Supervision always yet.
Can use owing to there is no legal diagnostic kit, the allergy doctor of China and dermatologist cannot carry out patch test, the cause of disease of contact dermatitis cannot be specified, autopath cannot take corresponding avoiding measures, skin lesion possibility chronicity, protracted course of disease, has a strong impact on the quality of life of patient, and long-term Drug therapy not only can bring huge medical expense, and serious side effect may be caused.
Therefore, we are necessary to develop domestic speckle examination device and patch reagent, by the safe and effective rear commercialization of clinical observation.
Utility model content
The purpose of this utility model is exactly provide a kind of easy and simple to handle for above-mentioned deficiency, saves time easy to learn, split type speckle examination device handy flexibly.
For achieving the above object, the technological means that this utility model adopts is, a kind of split type speckle examination device, comprise patch cell fixing head, patch cell, adhesive tape, described patch cell is at least one and separated from one another with adhesive tape, the preset filter paper in the little indoor of patch, described patch cell fixing head offers the hole slightly larger than patch cell.
Further, described adhesive tape is medical low sensitive tape.
Further, described adhesive tape is hypoallergenic adhesive waterproof tape.
Further, the material of described patch cell fixing head is rustless steel or aluminum or other inert metal materials.
Further, described patch cell is square, and the length of side is 5mm-10mm, preferred 8mm.
Further, the material of described patch cell is medical plastic or aluminum or other inert materials.
Described inert material refers to the material not easily causing allergy with contact skin, can select the various materials that this area is conventional.
The beneficial effects of the utility model are, owing to have employed split type patch cell, can add patch cell quantity and corresponding reagent as required flexibly; Simultaneously due to the preset filter paper in the little indoor of patch, both can be used for liquid patch reagent, also can with gluey patch reagent, especially easy to the patch reagent operation of solution morphology, simplify operating procedure, save the operating time.Can according to the situation of patient skin sensitivity, select that hypersensitive is lower, the low sensitive tape of the better high-quality of cohesiveness, it is easily irritated and adhesive tape attachment is bad causes false-negative problem to adhesive tape to solve patient; High-quality hypoallergenic adhesive waterproof tape can also be selected, solve patient (72-96 hour) during patch test and cannot to have a bath this obstinate problem uncomfortable brought.
Accompanying drawing explanation
Accompanying drawing 1 is structural representation of the present utility model.
Accompanying drawing 2 is structural representations of this utility model patch cell.
Detailed description of the invention
Below in conjunction with accompanying drawing, embodiment of the present utility model is described in detail.As shown in Figure 1, 2, split type speckle examination device of the present utility model, comprise patch cell fixing head 1, patch cell 2, adhesive tape 3, described patch cell 2 is at least one and separated from one another with adhesive tape 3, preset filter paper 4 in patch cell 2, described patch cell fixing head 1 offers the hole 5 slightly larger than patch cell 2.Described patch cell 2 is the square of length of side 8mm, and adhesive tape 3 selects medical low sensitive tape or hypoallergenic adhesive waterproof tape, the material selection rustless steel of patch cell fixing head and patch cell, plastics, aluminum or other inert materials.
During use, get appropriate adhesive tape 3, then the patch cell fixing head 1 of sterilizing is pasted onto on adhesive tape 3, the patch cell 2 getting some is as required placed in the hole 5 of patch cell fixing head 1, pressing makes patch cell 2 be pasted onto on adhesive tape 3 gently, then patch reagent is placed in preset filter paper 4 in patch cell 2, takes off patch cell fixing head 1, the adhesive tape 3 with patch cell 2 is affixed on the healthy skin outside the upper back of tester or upper arm.

Claims (7)

1. a split type speckle examination device, it is characterized in that: comprise patch cell fixing head (1), patch cell (2), adhesive tape (3), described patch cell (2) is at least one and separated from one another with adhesive tape (3), preset filter paper (4) in patch cell (2), described patch cell fixing head (1) offers the hole (5) slightly larger than patch cell (2).
2. split type speckle examination device as claimed in claim 1, is characterized in that: described adhesive tape (3) is medical low sensitive tape.
3. split type speckle examination device as claimed in claim 1 or 2, is characterized in that: described adhesive tape (3) is hypoallergenic adhesive waterproof tape.
4. split type speckle examination device as claimed in claim 1 or 2, is characterized in that: the material of described patch cell fixing head (1) is rustless steel or aluminum or other inert metal materials.
5. split type speckle examination device as claimed in claim 1 or 2, is characterized in that: described patch cell (2) is square, and the length of side is 5mm-10mm.
6. split type speckle examination device as claimed in claim 5, is characterized in that: the length of side of described patch cell (2) is 8mm.
7. the split type speckle examination device as described in claim 1 or 2 or 6, is characterized in that: the material of described patch cell (2) is medical plastic or aluminum or other inert materials.
CN201520181445.4U 2015-03-27 2015-03-27 A kind of split type speckle examination device Active CN204723097U (en)

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CN201520181445.4U CN204723097U (en) 2015-03-27 2015-03-27 A kind of split type speckle examination device

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Application Number Priority Date Filing Date Title
CN201520181445.4U CN204723097U (en) 2015-03-27 2015-03-27 A kind of split type speckle examination device

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106377282A (en) * 2016-09-23 2017-02-08 何韶衡 Allergen film applied to patch test and spot test device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106377282A (en) * 2016-09-23 2017-02-08 何韶衡 Allergen film applied to patch test and spot test device

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