CN204705589U - A kind of full-automatic fluorimetric assay for biological materials instrument on a large scale - Google Patents
A kind of full-automatic fluorimetric assay for biological materials instrument on a large scale Download PDFInfo
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- CN204705589U CN204705589U CN201520209649.4U CN201520209649U CN204705589U CN 204705589 U CN204705589 U CN 204705589U CN 201520209649 U CN201520209649 U CN 201520209649U CN 204705589 U CN204705589 U CN 204705589U
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Abstract
The utility model relates to a kind of full-automatic fluorimetric assay for biological materials instrument on a large scale, comprise ccd image controller, automatic control system and mechanical-optical setup, ccd image controller and the mutual control linkage of automatic control system, automatic control system and the mutual control linkage of mechanical-optical setup, marble platform is provided with bottom mechanical-optical setup, marble platform is provided with frame, frame lower end, marble platform is provided with light source switching mechanism, the optical imaging system of focusing jacking gear and focusing jacking gear control linkage, light source switching mechanism is provided with LED light source and color filter elements, the frame side of LED light source side is provided with fan, focusing jacking gear top is provided with the object lens in optical imaging system, frame top is provided with accurate sample stage.
Description
Technical field
The utility model relates to technical field of fluorescence detection, is specifically related to a kind of full-automatic fluorimetric assay for biological materials instrument on a large scale.
Background technology
Fluorescent microscope utilizes a high-luminous-efficiency pointolite, general employing high-pressure sodium lamp or LED are as fluorescence light source, fluorescence light source sends the light of certain wavelength as exciting light after color filter array, fluorescent material in sample is excited, make it the fluorescence launching various different colours, again by the amplification of micro objective and eyepiece, thus realize the observation of sample shape and structure.Strong under backing scape, also easily recognize even if fluorescence is very faint, susceptibility is very high, is mainly used in the researchs such as eucaryotic cell structure, function and chemical composition.Why we can observe sample, are because the fluorescence phenomenon presented after fluorescent material absorbs the luminous energy excited in sample.Therefore, the effect of fluorescent microscope light source is not direct illumination, but as a kind of energy exciting fluorescent material in sample.
But existing fluorescent microscope is owing to being subject to the restriction of objective angular field's size, when using fluorescence microscopy and shooting image, can only take very little specimen area, larger or a fairly large number of biological sample for that size, existing fluorescent microscope cannot meet the demands.Existing fluorescent microscope automaticity is very low simultaneously, all need manual switchover light source and color filter during work, manually find or mobile example observation area, make the work efficiency of instrument very low, cannot carry out sample online observation or the analysis of batch, range of application is limited.Therefore, a kind of full-automatic fluorimetric assay for biological materials instrument on a large scale newly of design is needed badly, to solve prior art above shortcomings.
Utility model content
The purpose of this utility model is to provide a kind of full-automatic fluorimetric assay for biological materials instrument on a large scale, to overcome currently available technology above shortcomings.
The purpose of this utility model is achieved through the following technical solutions:
A kind of full-automatic fluorimetric assay for biological materials instrument on a large scale, comprise ccd image controller, automatic control system and mechanical-optical setup, described ccd image controller and the mutual control linkage of automatic control system, described automatic control system and the mutual control linkage of mechanical-optical setup, marble platform is provided with bottom wherein said mechanical-optical setup, described marble platform is provided with frame, described frame lower end, marble platform is provided with light source switching mechanism, the optical imaging system of focusing jacking gear and described focusing jacking gear control linkage, described light source switching mechanism is provided with LED light source and color filter elements, the frame side of described LED light source side is provided with fan, described focusing jacking gear top is provided with the object lens in optical imaging system, described frame top is provided with accurate sample stage.
Further, described optical imaging system comprises LED light source, illuminator, fluorescence color filter group, object lens, tube lens, CCD adaptive mirror and CCD target surface.
Further, described optical imaging system is for being inverted imaging system.
The beneficial effects of the utility model are: reasonable in design, have employed high precision sample stage and the color filter switching device shifter of Automatic Control, and make use of ccd image splicing, autoscan imaging and analysis can be carried out to large-scale biological cell sample, greatly improve the work efficiency of fluorescent microscope, achieve it in medical treatment and industrial application simultaneously, extend range of application.
Accompanying drawing explanation
Below in order to be illustrated more clearly in the utility model embodiment or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment below, apparently, accompanying drawing in the following describes is only some embodiments of the application, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
Fig. 1 is the structural representation of a kind of full-automatic fluorimetric assay for biological materials instrument on a large scale described in the utility model embodiment;
Fig. 2 is the optical imaging system structural representation of a kind of full-automatic fluorimetric assay for biological materials instrument on a large scale described in the utility model embodiment.
In figure:
1, ccd image controller; 2, automatic control system; 3, mechanical-optical setup; 4, marble platform; 5, frame; 6, light source switching mechanism; 7, focusing jacking gear; 8, optical imaging system; 9, LED light source; 10, color filter elements; 11, fan; 12, object lens; 13, accurate sample stage; 14, color filter elements; 15, tube lens; 16, CCD adaptive mirror; 17, CCD target surface.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, be clearly and completely described the technical scheme in the utility model embodiment, obviously, described embodiment is only the utility model part embodiment, instead of whole embodiments.Based on the embodiment in the utility model, the every other embodiment that those of ordinary skill in the art obtain, all belongs to the scope of the utility model protection.
The full-automatic fluorimetric assay for biological materials instrument on a large scale of one as shown in Figure 1-2, comprise ccd image controller 1, automatic control system 2 and mechanical-optical setup 3, described ccd image controller 1 and automatic control system 2 control linkage mutually, described automatic control system 2 and mechanical-optical setup 3 control linkage mutually, marble platform 4 is provided with bottom wherein said mechanical-optical setup 3, described marble platform 4 is provided with frame 5, described frame 5 lower end, marble platform 4 is provided with light source switching mechanism 6, the optical imaging system 8 of focusing jacking gear 7 and described focusing jacking gear 7 control linkage, described optical imaging system 8 is for being inverted imaging system, described optical imaging system 8 comprises LED light source 9, illuminator 14, color filter elements 10, object lens 12, tube lens 15, CCD adaptive mirror 16 and CCD target surface 17, described light source switching mechanism 6 is provided with LED light source 9 and color filter elements 10, frame 5 side of described LED light source 9 side is provided with fan 11, described focusing jacking gear 7 top is provided with the object lens 12 in optical imaging system 8, described frame 5 top is provided with accurate sample stage 13.
During concrete use, biological cell sample to be measured is placed on accurate sample stage, and two-dimensional movement is carried out to the sample areas of scanning, start ccd image controller 1, input command, automatic control system 2 sends instruction to accurate sample stage 13, the movement of LED light source 9 and color filter elements 10 controls, and feed back to ccd image controller, namely ccd image controller takes pictures, light source switching mechanism 6 can switch the exciting light of different-waveband, realize multiband light exciting sample, because optical imaging system 8 is inverted imaging system, when sample is placed in object lens 12 upper end, LED light source is by after illuminator, after being filtered by color filter elements 10 again, be radiated on biological specimen, thus excite the fluorescent material in sample, make it the fluorescence launching various different colours, then fluorescence is amplified by object lens 12, and by entering CCD target surface after CCD adaptive mirror, present in the form of images eventually through ccd image controller.
The utility model is not limited to above-mentioned preferred forms; anyone can draw other various forms of products under enlightenment of the present utility model; no matter but any change is done in its shape or structure; every have identical with the application or akin technical scheme, all drops within protection domain of the present utility model.
Claims (3)
1. a full-automatic fluorimetric assay for biological materials instrument on a large scale, it is characterized in that, comprise ccd image controller (1), automatic control system (2) and mechanical-optical setup (3), described ccd image controller (1) and automatic control system (2) control linkage mutually, described automatic control system (2) and mechanical-optical setup (3) control linkage mutually, wherein said mechanical-optical setup (3) bottom is provided with marble platform (4), described marble platform (4) is provided with frame (5), described frame (5) lower end, marble platform (4) is provided with light source switching mechanism (6), the optical imaging system (8) of focusing jacking gear (7) and described focusing jacking gear (7) control linkage, described light source switching mechanism (6) is provided with LED light source (9) and color filter elements (10), frame (5) side of described LED light source (9) side is provided with fan (11), described focusing jacking gear (7) top is provided with the object lens (12) in optical imaging system (8), described frame (5) top is provided with accurate sample stage (13).
2. full-automatic fluorimetric assay for biological materials instrument on a large scale according to claim 1, it is characterized in that, described optical imaging system (8) comprises LED light source (9), illuminator (14), color filter elements (10), object lens (12), tube lens (15), CCD adaptive mirror (16) and CCD target surface (17).
3. full-automatic fluorimetric assay for biological materials instrument on a large scale according to claim 2, is characterized in that, described optical imaging system (8) is for being inverted imaging system.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201520209649.4U CN204705589U (en) | 2015-04-09 | 2015-04-09 | A kind of full-automatic fluorimetric assay for biological materials instrument on a large scale |
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| CN201520209649.4U CN204705589U (en) | 2015-04-09 | 2015-04-09 | A kind of full-automatic fluorimetric assay for biological materials instrument on a large scale |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104964953A (en) * | 2015-04-09 | 2015-10-07 | 苏州飞时曼精密仪器有限公司 | Automatic wide-range biological fluorescence analyser |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104964953A (en) * | 2015-04-09 | 2015-10-07 | 苏州飞时曼精密仪器有限公司 | Automatic wide-range biological fluorescence analyser |
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