CN204600538U - A kind of bionical vibration sampling device for biopsy - Google Patents
A kind of bionical vibration sampling device for biopsy Download PDFInfo
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- CN204600538U CN204600538U CN201520216414.8U CN201520216414U CN204600538U CN 204600538 U CN204600538 U CN 204600538U CN 201520216414 U CN201520216414 U CN 201520216414U CN 204600538 U CN204600538 U CN 204600538U
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- biopsy
- biopsy needle
- needle
- piezoelectric actuator
- closing member
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Abstract
This utility model belongs to biomedical engineering field, is a kind of bionical vibration sampling device for biopsy.It comprises feed arrangement, biopsy needle fixture, biopsy needle; Feed arrangement comprises hand-held handle, piezoelectric actuator, it is inner that piezoelectric actuator is fixed on hand-held handle, and be connected with biopsy needle by biopsy needle fixture, make biopsy needle sampling process along with the vibration of characteristic frequency and amplitude, piezoelectric actuator control port is connected with external controller.Biopsy needle outer surface is provided with axial pass trough and cross spacing groove, and the slip spanner be connected with nook closing member can slide and can be allocated to cross spacing groove in axial pass trough, and nook closing member afterbody is connected with a spring; Syringe needle inner surface is provided with cutting edge, agnail, axial groove and lateral trench, and being designed with of these structures is beneficial to tissue cut-out taking-up.This utility model effectively can reduce the frictional force of the process of thrusting, and the distortion of reduction tissue and biopsy needle thrust degree of crook, thus improve biopsy precision.
Description
Technical field
This utility model belongs to biomedical engineering field, relates to a kind of bionical vibration sampling device for biopsy, is the medical apparatus being applied to the medical items such as clinical biopsy sampling, percutaneous puncture.
Background technology
In recent years, the sickness rate of malignant tumor rises year by year.The last diagnostic of malignant tumor is pathocytology diagnosis, and pathocytology inspection is the unique method that can find malignant cell at present and can carry out typing to this.Do the tissue specimen that pathocytology inspection must obtain corresponding site, extracting tissue specimen at present clinically has two kinds of methods.One is aspiration biopsy, and two is surgical methods.Surgical method wound is large, and patient spends high, and the restriction being sometimes subject to economic condition and physical qualification is difficult to carry out, and therefore, aspiration biopsy is prefered method clinically.But be limited to current biopsy sampling equipment, in practical operation, the sampling efficiency of aspiration biopsy and sampling precision are all not fully up to expectations.The method of the raising sampling precision studied both at home and abroad at present mainly contains: the robot assisted aspiration biopsy method (Experimental studyof robotic needle insertion in soft tissue) that University of Western Ontario of (1) Britain Abolhassani invents, by the robot assisted lancing system designed and developed, in conjunction with CT, MRI, us guide technology, realize the position to puncture needle and gesture stability, thus improve puncture precision, reduce puncture error.But the method needs special robot assisted lancing system, cost intensive is difficult to popularize.(2) biopsy needle of the auspicious invention of Taiwan National Chenggong University Cai Ming is ultrasonic thrusts method (A piezoelectric vibration-based syringe for reducing insertionforce), biopsy needle is made to thrust the supersonic vibration of process with characteristic frequency, amplitude by plant equipment, biopsy needle can be reduced and thrust resistance suffered by process, improve sampling precision.But the method needs special ultrasound generating devices equally, equipment occupation space is large, and cost is higher, universal difficulty.
Along with the needs produced and scientific and technical development, since the 1950's, it has been recognized that biosystem is one of main path opening up new technique, consciously using the source of biosphere as various technological thought, design principle and creativity and innovation.There is many phenomenons being similar to Biopsy in occurring in nature, most typical example is exactly that mosquito mouthpart thrusts human body skin.Mosquito mouthpart is when thrusting human epidermal, and be attended by the vibration of frequency 2 ~ 16Hz, amplitude 30 ~ 90 μm, research shows, the vibration of this characteristic frequency, amplitude contributes to mosquito mouthpart and thrusts human epidermal fast and accurately.The puncture force of mosquito mouthpart prick skin and tissue is much less than the puncture force of artificial micropin, on average only has 18 μ N.
Summary of the invention
The purpose of this utility model is to overcome above-mentioned the deficiencies in the prior art, in conjunction with bionics knowledge, provides a kind of and thrusts sample when power and biopsy needle take out when reducing biopsy by bionical vibration, biomimetic features and to autotomy disconnected bionical vibration sampling device for biopsy.
This utility model is achieved in the following ways:
A kind of bionical vibration sampling device for biopsy, comprise feed arrangement, biopsy needle fixture, biopsy needle, biopsy needle comprises nook closing member and needle tubing two parts; It is characterized in that feed arrangement comprises hand-held handle, piezoelectric actuator, hand-held handle adopts ergonomic designs's method, the hand-held handle designed can make people feel comfortably cool, enough large grip can be produced again, for bionical vibration sampling device for biopsy provides not only reasonable but also practical external support, the piezoelectric actuator of frequency of vibration and amplitude is regulated to be arranged on hand-held handle inner, piezoelectric actuator is connected with biopsy needle by biopsy needle fixture, and piezoelectric actuator port is connected with external controller.
There are axial pass trough and cross spacing groove in biopsy needle surface, and the slip spanner be connected with nook closing member can slide and can be allocated to stopper slot in axial pass trough; Nook closing member afterbody is connected with spring, is compressive state when spring is initial, and spring afterbody is fixedly connected with needle tubing; During sampling, slip spanner drives nook closing member to slide into stopper slot, and spring compresses further, is sample of tissue vacating space simultaneously and forms local decompression's vacuum at syringe needle place, and aid in tissue is cut off and taken out; Biopsy needle inner surface has axial groove, cutting edge, agnail and lateral trench, and there is a gradient biopsy needle tip to cutting edge part.Gradient α excursion is 60 ~ 80 °.This gradient both can make needle point sharper, the tissue that entered by biopsy needle needle point also can be made larger than inner diameter in the middle part of biopsy needle, be conducive to the laminating of tissue and barb structure and the cut-out of cutting edge.When feed motion stops, the oscillating movement of biopsy needle makes cutting edge produce crack on biopsy cross section.When tissue samples is drawn out, stress can be produced around this crack and concentrate, thus human tissue sample is very easy to fracture herein.Biopsy needle inwall is provided with barb structure, and because biological tissue has certain elasticity, the tissue samples entered in biopsy needle can expand and fit in barb structure.When biopsy needle exits, these barb structure can hook biopsy, and biopsy can produce to external axial force, and this axial force makes human tissue sample rupture in cracks, and is pulled out by tissue samples.Finally the human tissue sample in biopsy needle is taken out.
The feature of above-mentioned bionical sampling device for biopsy is the vibration that biopsy needle sampling process is attended by that frequency is 2 ~ 16Hz, amplitude is 45 ~ 90 μm, and vibration, with whole sampling process, comprises the feeding of syringe needle and exits until sample end.This vibration is the vibration that similar mosquito mouthpart thrusts human body skin.This vibration can reduce resistance when biopsy needle thrusts, and when reducing to thrust, the distortion of biopsy needle and tissue, improves biopsy precision.
Compared with traditional biopsy device, this utility model is adopted to have following positive effect:
Adopt bionical vibration sampling device for biopsy to make biopsy needle thrust tissue, effectively can reduce the frictional force of the process of thrusting, the distortion of reduction tissue and biopsy needle thrust degree of crook, thus improve biopsy precision.Sample length is longer than traditional slot type sampling probe sampling, is conducive to later stage pathology detection.Operating procedure is few, and sampling is convenient.
Accompanying drawing explanation
Fig. 1 is overall structure schematic diagram of the present utility model.
Fig. 2 is portion of the handle profile of the present utility model.
Fig. 3 is biopsy needle clamp structure figure of the present utility model.
Fig. 4 is biopsy needle tail structure figure of the present utility model.
Fig. 5 is biopsy needle sectional structure chart of the present utility model.
Fig. 6 is biopsy needle section reduced graph of the present utility model.
Fig. 7 is biopsy needle cross-sectional view of the present utility model.
In figure, 1. hand-held handle, 2. biopsy needle fixture, 3. biopsy needle, 4. piezoelectric actuator, 5. piezoelectric actuator control port, 6. fixture nut, 7. chuck, 8. taenidium, 9. axial pass trough, 10. cross spacing groove, 11. slip spanners, 12 nook closing members, 13. springs, 14. axial grooves, 15. cutting edge, 16. agnails, 17 lateral trenchs.
Detailed description of the invention
Five most preferred embodiments of the present utility model are provided below in conjunction with accompanying drawing:
Embodiment one:
Consult Fig. 1: one of bionical vibration sampling device for biopsy important component part is feed arrangement.Be made up of the hand-held handle in outside (1), bionical vibrating device piezoelectric actuator (4) and biopsy needle fixture (2).Hand-held handle in conjunction with ergonomic designs's method, its structure can warrantor when sampling hand comfortable and can enough large grip be produced, simultaneously for the biopsy needle fixture (2) of inner bionical vibrating device and end provides support structure.Bionical vibrating device is piezoelectric actuator, piezoelectric actuator (4) adopts bolt to link with biopsy needle fixture (2), it can make biopsy needle produce a frequency is 2 ~ 16Hz, amplitude is the vibration of 30 ~ 90 μm, and the vibration that this vibration and mosquito mouthpart thrust human body skin is similar.Piezoelectric actuator control port (5) is connected with controller, can regulate frequency and the amplitude of vibration.Biopsy needle fixture (2) is special fixture, and turn fixture nut (6) i.e. adjustable holding degree of tightness, its structure as shown in Figure 3.
Consult Fig. 4, the outer surface of biopsy needle has an axial pass trough (9) and a cross spacing groove (10), nook closing member (12) is arranged a slip spanner (11), it can slide in longitudinal groove, thus drives nook closing member at needle tubing internal slide.Nook closing member afterbody arranges a spring (13), and the end of spring (13) is fixedly connected with biopsy needle afterbody.Time initial, spring (13) is in compressive state, after biopsy needle inserts tissue, cross spacing groove (10) is allocated to along groove (9) slip spanner (11) to longitudinal groove afterbody, now spring (13) compresses further, nook closing member slides toward needle tubing afterbody and at biopsy needle tip place for sampling vacating space forms local decompression's vacuum simultaneously, is conducive to tissue and cuts off taking-up.
Consult Fig. 5,6,7, biopsy needle internal structure by axial groove (14), cutting edge (15), agnail (16), lateral trench (17) totally three parts form.There is a gradient biopsy needle tip to cutting edge (15) part, this inclined-plane both can make needle point sharper, also the tissue diameter entering biopsy needle can be made more bigger than biopsy needle inner diameter, be conducive to the laminating of tissue and barb structure and the cut-out of cutting edge.In figure, the cross sectional shape of cutting edge (15) is rectangle, and the length of the groove at the gradient of cutting edge (15), width and two ends can change.The gradient α excursion of cutting edge (15) is 60 ~ 80 ° of degree of depth h1 excursions is 0.05 ~ 0.1mm, and the length a excursion of groove is 1 ~ 2mm.The width b of lateral trench (17) and the spacing distance c between degree of depth h2 and agnail can change.For A position, degree of depth h2 excursion is 0.08 ~ 0.1mm, and width b excursion is 1 ~ 2mm, and the distance c excursion between agnail is 2 ~ 3mm.In figure, the cross sectional shape of axial groove (14) is rectangle, and simultaneously the cross sectional shape of groove also can be rectangle, V-arrangement, parabola shaped.The excursion of cross sectional shape width d is 0.1 ~ 0.3mm.The excursion of gash depth h3 is 0.05 ~ 0.1mm.The length of groove can change, and length is penetrating to biopsy needle tip bevels, and excursion is 10 ~ 50mm.Design parameter is desirable:
The cross sectional shape of cutting edge is rectangle, gradient α=60 ° of cutting edge (15), width h1=0.5mm, the length a=1mm of groove.The width b of the trench structure A before agnail (16) and the spacing distance c between degree of depth h2 and agnail can change.Groove A degree of depth h2=0.08mm before agnail, width b=1mm, the distance c=2mm between agnail.The cross sectional shape of axial groove is rectangle.Cross sectional shape width d=0.1mm.Gash depth h3=0.05mm.The length 10mm of groove.
Embodiment two:
The cross sectional shape of cutting edge is rectangle, gradient α=70 ° of cutting edge (15), width h1=0.6mm, the length a=1.5mm of groove.The width b of the trench structure A before agnail (16) and the spacing distance c between degree of depth h2 and agnail can change.Groove A degree of depth h2=0.08mm before agnail, width b=1.5mm, the distance c=2.5mm between agnail.The cross sectional shape of axial groove is rectangle.Cross sectional shape width d=0.2mm.Gash depth h3=0.08mm.The length 30mm of groove.All the other are with embodiment one.
Embodiment three:
The cross sectional shape of cutting edge is rectangle, gradient α=80 ° of cutting edge (15), width h1=0.8mm, the length a=2mm of groove.The width b of the trench structure A before agnail (16) and the spacing distance c between degree of depth h2 and agnail can change.Groove A degree of depth h2=0.1mm before agnail, width b=2mm, the distance c=3mm between agnail.The cross sectional shape of axial groove is rectangle.Cross sectional shape width d=0.3mm.Gash depth h3=0.1mm.The length 50mm of groove.All the other are with embodiment one.
Embodiment four:
Consult Fig. 1, changing biopsy needle (3) is acupuncture needle, and biopsy needle fixture (2) still can be used as the fixture of acupuncture needle.Acupuncture under the guidance of theory of Chinese medical science, needle set (being often referred to acupuncture needle) is thrust in patient body according to certain angle, use twisted with put forward the manipulation of acupuncture such as slotting to stimulating human body specific part thus reaching the object of disease therapy.Device of the present utility model can provide carrying of reliable rule to insert motion for acupuncture needle, alleviates the working strength of acupuncturist.Acupuncture needle can be made to carry in twisted process slotting, improve acupuncture efficiency.All the other are with embodiment one.
Embodiment five:
Consult Fig. 1, replacing biopsy needle fixture (2) and biopsy needle (3) are scalpel clamper and scalpel, can develop for operating scalpel hand-held device, vibrate assisted surgery cutter to biological tissue's cutting effect for surgical operation and research.All the other are with embodiment one.
Claims (2)
1. a bionical vibration sampling device for biopsy, comprise feed arrangement, biopsy needle fixture (2), biopsy needle (3), biopsy needle (3) comprises nook closing member and needle tubing two parts; It is characterized in that feed arrangement comprises hand-held handle (1), piezoelectric actuator (4), the piezoelectric actuator (4) of frequency of vibration and amplitude is regulated to be arranged on hand-held handle (1) inner, piezoelectric actuator (4) is connected with biopsy needle (3) by biopsy needle fixture (2), and piezoelectric actuator control port (5) is connected with external controller; There are axial pass trough (9) and cross spacing groove (10) in biopsy needle (3) surface, and the slip spanner (11) be connected with nook closing member (12) can slide and can be allocated to cross spacing groove (10) in axial pass trough (9); Nook closing member afterbody is connected with spring (13), and be compressive state when spring (13) is initial, spring (13) afterbody is fixedly connected with needle tubing; During sampling, slip spanner (11) drives nook closing member (12) to slide into cross spacing groove (10), spring (13) compresses further, is sample of tissue vacating space simultaneously and forms local decompression's vacuum at syringe needle place, and aid in tissue is cut off and taken out; Biopsy needle (3) inner surface has axial groove (14), cutting edge (15), agnail (16) and lateral trench (17), and needle tip has a gradient to cutting edge part.
2. the bionical vibration sampling device for biopsy of one according to claim 1, is characterized in that needle tip is 60 ~ 80 ° to the gradient of cutting edge part.
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CN201520216414.8U CN204600538U (en) | 2015-04-10 | 2015-04-10 | A kind of bionical vibration sampling device for biopsy |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104783841A (en) * | 2015-04-10 | 2015-07-22 | 山东大学 | Bionic vibration biopsy sampling device |
CN109363929A (en) * | 2018-10-17 | 2019-02-22 | 江苏大学 | A kind of acupuncture-moxibustion therapy method and its device that ultrasonic vibration is combined with traditional acupuncture |
CN113842544A (en) * | 2021-10-18 | 2021-12-28 | 中南大学 | Percutaneous permeation-promoting drug delivery device |
-
2015
- 2015-04-10 CN CN201520216414.8U patent/CN204600538U/en not_active Withdrawn - After Issue
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104783841A (en) * | 2015-04-10 | 2015-07-22 | 山东大学 | Bionic vibration biopsy sampling device |
CN104783841B (en) * | 2015-04-10 | 2017-03-08 | 山东大学 | A kind of bionical vibration sampling device for biopsy |
CN109363929A (en) * | 2018-10-17 | 2019-02-22 | 江苏大学 | A kind of acupuncture-moxibustion therapy method and its device that ultrasonic vibration is combined with traditional acupuncture |
CN109363929B (en) * | 2018-10-17 | 2020-11-20 | 江苏大学 | Acupuncture method and device combining ultrasonic vibration and traditional acupuncture |
CN113842544A (en) * | 2021-10-18 | 2021-12-28 | 中南大学 | Percutaneous permeation-promoting drug delivery device |
CN113842544B (en) * | 2021-10-18 | 2023-01-24 | 中南大学 | Percutaneous permeation-promoting drug delivery device |
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Legal Events
Date | Code | Title | Description |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
AV01 | Patent right actively abandoned |
Granted publication date: 20150902 Effective date of abandoning: 20171114 |
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AV01 | Patent right actively abandoned |