CN204583372U - A kind of water miscible disintegrating apparatus improving Sulfamonomethoxime Sodium soluble powder - Google Patents
A kind of water miscible disintegrating apparatus improving Sulfamonomethoxime Sodium soluble powder Download PDFInfo
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Abstract
本实用新型公开了一种提高磺胺间甲氧嘧啶钠可溶性粉的水溶性的粉碎设备,包括粉碎装置主体,所述粉碎装置主体包括上箱体、磨碎腔和对称设置在磨碎腔两边的粉碎腔,所述粉碎腔倾斜设计,且腔体低一端出口设计有一级滤网,腔体下底外壁设有振动器;所述磨碎腔由两个粉碎腔出口的一级滤网、磨碎腔顶部的密封板和二级滤网构成。本实用新型中粉碎刀片在转轴上安装定位简单,一个刀齿损坏只需更换一块粉碎刀片即可,降低使用成本;磨碎刀第二刀片的向上翘起两端部在磨碎物品的同时,能够将物品向下推向第一刀片的磨碎范围内;刀具的双层设置增加了粉碎范围;整个设备粉碎效果好效率高,有效提高磺胺间甲氧嘧啶钠可溶性粉的水溶性。
The utility model discloses a pulverizing device for improving the water solubility of sulfamethoxine sodium soluble powder, which comprises a main body of a pulverizing device, and the main body of the pulverizing device includes an upper box body, a grinding chamber and symmetrically arranged grinding chambers on both sides of the grinding chamber. The crushing chamber is designed obliquely, and the outlet at the lower end of the chamber is designed with a primary filter screen, and the outer wall of the lower bottom of the cavity is provided with a vibrator; the grinding chamber is composed of two primary filter screens at the outlet of the crushing chamber, a The sealing plate on the top of the crushing chamber is composed of a secondary filter screen. In the utility model, the installation and positioning of the crushing blade on the rotating shaft is simple. If one tooth is damaged, only one crushing blade needs to be replaced, which reduces the cost of use. It can push the item down to the grinding range of the first blade; the double-layer setting of the cutter increases the grinding range; the whole equipment has good grinding effect and high efficiency, and can effectively improve the water solubility of sulfamethoxine sodium soluble powder.
Description
技术领域 technical field
本实用新型涉及一种粉碎设备,具体是一种提高磺胺间甲氧嘧啶钠可溶性粉的水溶性的粉碎设备。 The utility model relates to a crushing device, in particular to a crushing device for improving the water solubility of sulfamethoxine sodium soluble powder.
背景技术 Background technique
磺胺间甲氧嘧啶钠是体内外抗菌作用最强的磺胺药,对大多数革兰氏阳性菌和阴性菌都有较强抑制作用,细菌对此药产生耐药性较慢。在制备磺胺间甲氧嘧啶钠药品时,需要先对进行粉碎,再进行后续的过筛、混合、分剂量、质量检查、包装等工序;现有的粉碎装置,大多采用圆柱管状结构加上手工挤压研磨棒或锥形活塞从而粉碎药物,此类器械耗时费力且粉碎效果不佳,粉碎不完全的大颗粒会对药物使用效果造成影响;圆柱管状结构及内壁磨砂、螺纹、凸点等帮助研磨的设计,容易药物残留和清洁不便;现有的大部分设计在研磨过程中不密闭,易丢损药物并增加了被杂质污染的可能。并且现有技术中的刀具通常为一字型结构,在搅拌过程中虽然可以粉碎药品,但是被粉碎刀具碎粉的药品容易甩到刀片的上方,从而降低了粉碎刀具的粉碎效率,不能有效提高磺胺间甲氧嘧啶钠可溶性粉的水溶性,因此,需要加以改进。 Sulfamethoxine sodium is the sulfa drug with the strongest antibacterial effect in vivo and in vitro. It has a strong inhibitory effect on most Gram-positive bacteria and negative bacteria, and bacteria are slow to develop resistance to this drug. When preparing sulfamethoxine sodium medicine, it is necessary to pulverize it first, and then carry out subsequent processes such as screening, mixing, dosage, quality inspection, and packaging; most of the existing pulverization devices adopt cylindrical tubular structure and manual Squeeze the grinding rod or conical piston to pulverize the medicine. This kind of equipment is time-consuming and laborious and the pulverization effect is not good. The incomplete pulverization of large particles will affect the efficacy of the medicine; the cylindrical tubular structure and the inner wall are frosted, threads, bumps, etc. The design that aids grinding is prone to drug residues and inconvenient cleaning; most of the existing designs are not airtight during the grinding process, which is easy to lose drugs and increase the possibility of contamination by impurities. Moreover, the cutters in the prior art are usually in a straight shape. Although the medicine can be crushed during the stirring process, the medicine that is crushed by the crushing cutter is easily thrown to the top of the blade, thereby reducing the crushing efficiency of the crushing cutter and cannot effectively improve The water solubility of sulfamethoxine sodium soluble powder, therefore, needs to be improved.
实用新型内容 Utility model content
本实用新型的目的在于提供一种提高磺胺间甲氧嘧啶钠可溶性粉的水溶性的粉碎设备,以解决上述背景技术中提出的问题。 The purpose of this utility model is to provide a kind of pulverizing equipment that improves the water solubility of sulfamethoxine sodium soluble powder, to solve the problem that proposes in the above-mentioned background technology.
为实现上述目的,本实用新型提供如下技术方案: In order to achieve the above object, the utility model provides the following technical solutions:
一种提高磺胺间甲氧嘧啶钠可溶性粉的水溶性的粉碎设备,包括粉碎装置主体,所述粉碎装置主体包括上箱体、磨碎腔和对称设置在磨碎腔两边的粉碎腔,所述粉碎腔内设有粉碎刀,所述磨碎腔内设置有磨碎刀;所述粉碎刀通过传动杆连接到位于上箱体中的粉碎电机,所述磨碎刀通过转动杆连接到位于上箱体中的磨碎电机;所述粉碎刀和磨碎刀均设置为双层;所述粉碎腔倾斜设计,且腔体低一端出口设计有一级滤网,腔体下底外壁设有振动器,振动器连接电源;所述磨碎腔由两个粉碎腔出口的一级滤网、磨碎腔顶部的密封 板和二级滤网构成;所述粉碎腔设有加料口;药粉收集器下端设置有卸料阀,所述粉碎腔下端设置有支撑架。 A crushing device for improving the water solubility of sulfamethoxine sodium soluble powder, comprising a crushing device main body, the crushing device main body including an upper box, a grinding chamber and a crushing chamber symmetrically arranged on both sides of the grinding chamber, the There is a crushing knife in the crushing cavity, and a grinding knife is arranged in the grinding chamber; the crushing knife is connected to the crushing motor located in the upper box through a transmission rod, and the grinding knife is connected to the upper box through a rotating rod. Grinding motor in the box; the pulverizing knife and the grinding knife are both arranged in double layers; the pulverizing chamber is designed with an inclination, and the outlet at the lower end of the chamber is designed with a first-stage filter screen, and the outer wall of the lower bottom of the chamber is equipped with a vibrator , the vibrator is connected to the power supply; the grinding chamber is composed of two primary filter screens at the outlet of the grinding chamber, a sealing plate at the top of the grinding chamber and a secondary filter screen; the grinding chamber is provided with a feeding port; the lower end of the powder collector A discharge valve is provided, and a support frame is provided at the lower end of the crushing chamber.
作为本实用新型进一步的方案:所述粉碎刀设置有粉碎刀片,粉碎刀片通过螺栓相互连接。 As a further solution of the utility model: the crushing knife is provided with crushing blades, and the crushing blades are connected to each other by bolts.
作为本实用新型再进一步的方案:所述磨碎刀设置有第一刀片和第二刀片。 As a further solution of the utility model: the grating knife is provided with a first blade and a second blade.
作为本实用新型再进一步的方案:所述卸料阀上设置有卸料开关。 As a further solution of the utility model: the discharge valve is provided with a discharge switch.
与现有技术相比,本实用新型的有益效果是:粉碎腔设计有10°~40°的倾斜角度,既能让粉碎刀完成粉碎工作,同时,粉碎后的药粉及小型药物块可在振动器的作用下倾斜下滑,一部分通过一级滤网进入磨碎环节,一部分继续留在粉碎腔中,继续进行初级粉碎。这种结构可让药粉在自身重力的作用下,下滑,加快粉碎进度,同时,一级滤网的设置,可让部分较大的药物块继续留在粉碎腔中,从而提高了粉碎的效果;磨碎腔顶部设有密封板,使得药粉及小型药物块是在基本封闭的空间进行磨碎,有利于磨碎后的药粉收集。由于设置有二级滤网和磨碎盘,可以对通过了一级滤网的小型药物块进行再次磨碎,再次磨碎后的药粉通过二级滤网掉落到药粉收集器中,若再次磨碎后的小型药物块还不能通过二级滤网,则其会留在磨碎腔内继续磨碎。磨碎盘设置为两个,提高了磨碎程度和磨碎效率;本实用新型易于实现,其应用,能够快速粉碎药物,并能快速收集药粉,粉碎效果好,效率高。粉碎刀的结构,刀片安装部横截面为六角形,粉碎刀片的中部设有六角形的安装孔,两端分别设有刀齿,多块粉碎刀片在转轴上依次旋转60度;粉碎刀片在转轴上安装定位简单,一个刀齿损坏只需更换一块粉碎刀片即可,降低使用成本。磨碎刀的结构,通过将第一刀片的两端部分别向上下翘起,而第二刀片的两端部均向上翘起,第一刀片上下翘起的端部有效的增大的粉碎范围,而第二刀片的向上翘起两端部在粉碎物品的同时,能够将物品向下推向第一刀片的粉碎范围内,从而减少物品甩到粉碎刀具的上方,实现提高了粉碎刀具的粉碎效率;整个刀具双层式的设计使药粉磨的更加彻底,接触面更广,有效提高磺胺间甲氧嘧啶钠可溶性粉的水溶性。 Compared with the prior art, the beneficial effect of the utility model is: the crushing chamber is designed with an inclination angle of 10°-40°, which can not only allow the crushing knife to complete the crushing work, but also the crushed medicine powder and small medicine blocks can be vibrated Under the action of the device, it slides down, part of it enters the grinding link through the primary filter, and part of it stays in the grinding chamber to continue the primary grinding. This structure allows the drug powder to slide down under the action of its own gravity, speeding up the crushing progress. At the same time, the setting of the primary filter allows some larger drug pieces to remain in the crushing chamber, thereby improving the crushing effect; The top of the grinding chamber is equipped with a sealing plate, so that the powdered medicine and small pieces of medicine are ground in a basically closed space, which is beneficial to the collection of the powdered medicine after grinding. Since the secondary filter screen and the grinding disc are provided, the small drug blocks that have passed through the primary filter screen can be ground again, and the re-grinded drug powder falls into the powder collector through the secondary filter screen. The small drug pieces after grinding cannot pass through the secondary filter screen, so they will stay in the grinding chamber to continue grinding. There are two grinding discs, which improves the degree of grinding and grinding efficiency; the utility model is easy to realize, and its application can quickly crush medicine and quickly collect medicine powder, and the grinding effect is good and the efficiency is high. The structure of the crushing knife, the cross-section of the blade installation part is hexagonal, the middle part of the crushing blade is provided with a hexagonal mounting hole, and the two ends are respectively equipped with knife teeth, and multiple crushing blades rotate 60 degrees on the rotating shaft in turn; the crushing blades are on the rotating shaft The upper installation and positioning are simple, and only one crushing blade needs to be replaced if one tooth is damaged, which reduces the cost of use. The structure of the grinding knife, by tilting both ends of the first blade up and down, and both ends of the second blade are tilted up, the end of the first blade tilted up and down can effectively increase the crushing range , while the upward tilted ends of the second blade can push the object down to the crushing range of the first blade while crushing the object, thereby reducing the throwing of the object above the crushing cutter and improving the crushing of the crushing cutter Efficiency; the double-layer design of the entire cutter makes the powder grinding more thorough and the contact surface wider, effectively improving the water solubility of sulfamethoxine sodium soluble powder.
附图说明 Description of drawings
图1为提高磺胺间甲氧嘧啶钠可溶性粉的水溶性的粉碎设备的结构示意图。 Fig. 1 is the schematic structural view of the crushing equipment for improving the water solubility of sulfamethoxine sodium soluble powder.
图2为提高磺胺间甲氧嘧啶钠可溶性粉的水溶性的粉碎设备中粉碎刀的结构示意图。 Fig. 2 is a structural schematic diagram of a crushing knife in a crushing device for improving the water solubility of sulfamethoxine sodium soluble powder.
图3为提高磺胺间甲氧嘧啶钠可溶性粉的水溶性的粉碎设备中磨碎刀的结构示意图。 Fig. 3 is a structural schematic diagram of a grinding knife in a pulverizing device for improving the water solubility of sulfamethoxine sodium soluble powder.
图中:1-上箱体、2-药粉收集器、3-粉碎腔、4-磨碎腔、5-一级滤网、6-粉碎刀、61-粉碎刀片、62-螺栓、7-粉碎电机、8-传动杆、9-振动器、10-加料口、11-二级滤网、12-磨碎刀、121-第一刀片、122-第二刀片、13-磨碎电机、14-转动杆、15-密封板、16-卸料阀、17-卸料开关、18-支撑架。 In the figure: 1-upper box, 2-powder collector, 3-crushing chamber, 4-grinding chamber, 5-primary filter, 6-crushing knife, 61-crushing blade, 62-bolt, 7-crushing Motor, 8-transmission rod, 9-vibrator, 10-feeding port, 11-secondary filter, 12-grinding knife, 121-first blade, 122-second blade, 13-grinding motor, 14- Turning rod, 15-sealing plate, 16-discharge valve, 17-discharge switch, 18-support frame.
具体实施方式 Detailed ways
下面将结合本实用新型实施例中的附图,对本实用新型实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本实用新型一部分实施例,而不是全部的实施例。基于本实用新型中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本实用新型保护的范围。 The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. example. Based on the embodiments of the present utility model, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of the present utility model.
请参阅图1-3,本实用新型实施例中,一种提高磺胺间甲氧嘧啶钠可溶性粉的水溶性的粉碎设备,包括粉碎装置主体和药粉收集器2,所述粉碎装置主体包括上箱体1、磨碎腔4和对称设置在磨碎腔4两边的粉碎腔3,所述粉碎腔3倾斜设计,且腔体低一端出口设计有一级滤网5,腔体下底外壁设有振动器9,振动器9连接电源;所述磨碎腔4由两个粉碎腔3出口的一级滤网5、磨碎腔4顶部的密封板15和二级滤网11构成;所述粉碎腔3设有加料口10;所述药粉收集器2下端设置有卸料阀16,所述卸料阀16上设置有卸料开关17,所述粉碎腔3下端设置有支撑架18。 Please refer to Fig. 1-3, in the utility model embodiment, a kind of pulverizing equipment that improves the water solubility of sulfamethoxine sodium soluble powder comprises pulverizing device main body and medicine powder collector 2, and described pulverizing device main body comprises upper box Body 1, grinding chamber 4 and crushing chamber 3 symmetrically arranged on both sides of the grinding chamber 4, the crushing chamber 3 is designed to be inclined, and the outlet at the lower end of the chamber is designed with a primary filter 5, and the outer wall of the lower bottom of the chamber is provided with a vibrating 9, the vibrator 9 is connected to the power supply; the grinding chamber 4 is composed of the primary filter screen 5 at the outlet of the two grinding chambers 3, the sealing plate 15 and the secondary filter screen 11 at the top of the grinding chamber 4; the grinding chamber 3 is provided with a feeding port 10; the lower end of the powder collector 2 is provided with a discharge valve 16, the discharge valve 16 is provided with a discharge switch 17, and the lower end of the crushing chamber 3 is provided with a support frame 18.
将待粉碎的磺胺间甲氧嘧啶钠可溶性粉,从加料口10加入后,首先进入粉碎腔3,粉碎腔3中设有四个相同的粉碎刀6,所述粉碎刀6中的两个同时通过传动杆8连接到位于上箱体1中的粉碎电机7,粉碎电机7连接到电源,电源给粉碎电机7供电,粉碎电机7工作,使得传动杆8转动,从而带动粉碎刀6转动工作进行粉碎;粉碎腔3有10°~40°的倾斜角度,既能让粉碎刀6完成粉碎工作,同时,粉碎后的药粉及小型药物块可在振动器9的作用下倾斜下滑,一部分通过一级滤网5进入磨碎环节,一部分继续留在粉碎腔3 中,继续进行初级粉碎。这种结构可让药粉在自身重力的作用下,下滑,加快粉碎进度,同时,一级滤网5的设置,可让部分较大的药物块继续留在粉碎腔3中,从而提高了粉碎的效果。 After the sulfamethoxine sodium soluble powder to be pulverized is added from the feeding port 10, it first enters the pulverizing chamber 3, and the pulverizing chamber 3 is provided with four identical pulverizing knives 6, and two of the pulverizing knives 6 simultaneously The transmission rod 8 is connected to the pulverizing motor 7 located in the upper box body 1, the pulverizing motor 7 is connected to the power supply, the power supply supplies power to the pulverizing motor 7, and the pulverizing motor 7 works to make the transmission rod 8 rotate, thereby driving the pulverizing knife 6 to rotate and work. Crushing; the crushing chamber 3 has an inclination angle of 10° to 40°, which can not only allow the crushing knife 6 to complete the crushing work, but at the same time, the crushed medicine powder and small drug blocks can be tilted down under the action of the vibrator 9, and some of them can pass through the first stage. The filter screen 5 enters the grinding link, and a part remains in the grinding chamber 3 for primary grinding. This structure allows the medicine powder to slide down under the action of its own gravity to speed up the crushing progress. At the same time, the setting of the primary filter 5 allows some larger drug pieces to remain in the crushing chamber 3, thereby improving the crushing efficiency. Effect.
进入到磨碎腔4后,由于磨碎腔4为圆柱型腔体,其内设有四个磨碎刀12,其中两个相同的磨碎刀12同时通过转动杆14连接到位于上箱体1中的磨碎电机13,磨碎电机13连接电源,电源给磨碎电机13供电,磨碎电机13工作,使得转动杆14转动,从而带动磨碎刀12转动工作,与磨碎腔4底部内壁配合对药物进行磨碎;通过一级滤网5后的药物在磨碎腔4中进行再次磨碎,再通过二级滤网11掉落到药粉收集器2中。 After entering the grinding chamber 4, since the grinding chamber 4 is a cylindrical cavity, four grinding knives 12 are arranged in it, and two of the same grinding knives 12 are connected to the upper box body through the rotating rod 14 at the same time. The grinding motor 13 in 1, the grinding motor 13 is connected to the power supply, the power supply supplies power to the grinding motor 13, and the grinding motor 13 works to make the rotating rod 14 rotate, thereby driving the grinding knife 12 to rotate and work, and the grinding chamber 4 bottom The inner wall cooperates to grind the medicine; the medicine passing through the primary filter 5 is ground again in the grinding chamber 4 , and then falls into the powder collector 2 through the secondary filter 11 .
请参阅图2,所述粉碎刀6包括多块粉碎刀片61,多块所述粉碎刀片61通过多根螺栓62连接,所述粉碎刀片61的中部设有六角形的安装孔,两端分别设有刀齿,多块所述粉碎刀片61依次旋转60度。 Please refer to Fig. 2, described pulverizing blade 6 comprises a plurality of pulverizing blades 61, and a plurality of described pulverizing blades 61 are connected by a plurality of bolts 62, and the middle part of described pulverizing blade 61 is provided with hexagonal installation hole, and two ends are respectively provided with There are knife teeth, and a plurality of crushing blades 61 rotate 60 degrees in turn.
请参阅图3,所述的磨碎刀12上设置有第一刀片121和第二刀片122,其中,第一刀片121的两端部分别超上下翘起,第一刀片121向不同方向翘起的端部可以有效的增大第一刀片121的磨碎范围;第二刀片122的两端部均朝上翘起,在磨碎刀具进行磨碎药粉时,第一刀片121能够最大范围的对药粉进行磨碎,而第二刀片122在磨碎物粉的同时能够将第一刀片121甩到上部的物粉重新推向第一刀片121,从而可以减少药粉被甩到磨碎刀具的上部而无法被磨碎的现象发生,有效的提高了磨碎刀具的磨碎效率。其中,第一刀片121跷起部的面积小于第二刀片122跷起部的面积,通过设置较大面积的第二刀片122的跷起部,可以通过第二刀片122的跷起部最大限度的将第一刀片121向上甩出的药粉重新推向第一刀片121,以使药粉能够被充分磨碎。 Please refer to Fig. 3, the first blade 121 and the second blade 122 are arranged on the described grating knife 12, wherein, the two ends of the first blade 121 are super up and down respectively, and the first blade 121 is tilted in different directions The end of the blade can effectively increase the grinding range of the first blade 121; the two ends of the second blade 122 are all tilted upwards, and when the grinding tool grinds the powder, the first blade 121 can be used for the maximum range. The medicine powder is ground, and the second blade 122 can push the material powder thrown to the upper part of the first blade 121 to the first blade 121 again when grinding the material powder, thereby reducing the problem of the medicine powder being thrown to the upper part of the grinding tool. The phenomenon of being unable to be ground occurs, which effectively improves the grinding efficiency of the grinding tool. Wherein, the area of the first blade 121 is less than the area of the second blade 122, by setting the larger area of the second blade 122, the second blade 122 can be maximized by the second blade 122. The medicinal powder thrown upward by the first blade 121 is pushed to the first blade 121 again, so that the medicinal powder can be fully ground.
对于本领域技术人员而言,显然本实用新型不限于上述示范性实施例的细节,而且在不背离本实用新型的精神或基本特征的情况下,能够以其他的具体形式实现本实用新型。因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本实用新型的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含 义和范围内的所有变化囊括在本实用新型内。不应将权利要求中的任何附图标记视为限制所涉及的权利要求。 It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, no matter from all points of view, the embodiments should be regarded as exemplary and non-restrictive, and the scope of the present invention is defined by the appended claims rather than the above description, so it is intended to fall within the scope of the claims All changes within the meaning and range of the required equivalent elements are included in the present invention. Any reference sign in a claim should not be construed as limiting the claim concerned.
此外,应当理解,虽然本说明书按照实施方式加以描述,但并非每个实施方式仅包含一个独立的技术方案,说明书的这种叙述方式仅仅是为清楚起见,本领域技术人员应当将说明书作为一个整体,各实施例中的技术方案也可以经适当组合,形成本领域技术人员可以理解的其他实施方式。 In addition, it should be understood that although this specification is described according to implementation modes, not each implementation mode only contains an independent technical solution, and this description in the specification is only for clarity, and those skilled in the art should take the specification as a whole , the technical solutions in the various embodiments can also be properly combined to form other implementations that can be understood by those skilled in the art.
Claims (4)
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| CN201520239005.XU CN204583372U (en) | 2015-04-20 | 2015-04-20 | A kind of water miscible disintegrating apparatus improving Sulfamonomethoxime Sodium soluble powder |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108393155A (en) * | 2018-05-30 | 2018-08-14 | 山东省中医药研究院 | The medicinal herb grinder that fine drug powder can detach in time in a kind of crushing process |
| CN109926156A (en) * | 2017-12-15 | 2019-06-25 | 南京机器人研究院有限公司 | A kind of medicinal powder dispersing device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109926156A (en) * | 2017-12-15 | 2019-06-25 | 南京机器人研究院有限公司 | A kind of medicinal powder dispersing device |
| CN108393155A (en) * | 2018-05-30 | 2018-08-14 | 山东省中医药研究院 | The medicinal herb grinder that fine drug powder can detach in time in a kind of crushing process |
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