CN204490778U - A kind of device for resin elution in heparin leaching process - Google Patents
A kind of device for resin elution in heparin leaching process Download PDFInfo
- Publication number
- CN204490778U CN204490778U CN201520163822.1U CN201520163822U CN204490778U CN 204490778 U CN204490778 U CN 204490778U CN 201520163822 U CN201520163822 U CN 201520163822U CN 204490778 U CN204490778 U CN 204490778U
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- cover
- cylindrical shell
- resin
- feed
- opening
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Abstract
The utility model discloses a kind of device for resin elution in heparin leaching process, comprise the cylindroid cylindrical shell of bottom, and the cover matched with cylindrical shell, cylindrical shell and cover junction surface are a scarp; Cover top is provided with opening for feed, and opening for feed covers half, cover top cambered surface, and cover bottom is provided with hygrosensor; Another cambered surface of cover top is inserted with heating rod and pH value detector, and heating rod and pH value detector all extend in cylindrical shell; Also be provided with whipping appts in cylindrical shell, be provided with resin isolation screen cloth below whipping appts, cylinder body bottom center is also provided with liquid outlet.The utility model, by setting up hygrosensor and pH value detector, can monitor the wash-out environment in resin elution device in real time, makes in resin elution device and remains good wash-out environment, improves elution efficiency; By the bonding surface of cylindrical shell and cover is set to inclined-plane, expand the surface-area of cover, reserve a larger opening for feed, conveniently can reclaim resin from opening for feed.
Description
Technical field
The utility model relates to heparin sodium extraction equipment field, specifically refers to a kind of device for resin elution in heparin leaching process.
Background technology
Heparin is the anticoagulant of widespread use clinically at present, along with the raising of social life level and the development of medicinal career, the demand day of heparin overflows and increases, and each pharmaceutical equipment manufacturing concern is also updating product performance, to meet the requirement of market to heparin seed output and quality.But the resin elution jar structure function for heparin production before target is all fairly simple, and resin needs certain temperature and special acid or alkali environment when wash-out heparin, existing resin elution tank, all the control carrying out temperature and acid or alkali environment in advance, but along with the wash-out of resin, temperature in wash-out tank and acid or alkali environment all change, and are not beneficial to the wash-out of heparin; Existing resin elution tank is all the screen clothes arranging resin at liquid outlet place, but resolves to liquid environment due to place, wash-out top tank structure can be attached with the resin of part, the resin of wash-out tank inside is recycled, and also needs to be reclaimed by bottom liquid outlet, extremely inconvenient.
Utility model content
The purpose of this utility model be to provide one can when wash-out Real-Time Monitoring temperature and acid or alkali environment, and adjustment in time, the convenient device reclaiming the resin elution of resin.
The utility model is achieved through the following technical solutions: a kind of device for resin elution in heparin leaching process, comprises the cylindroid cylindrical shell of bottom, and the cover matched with cylindrical shell, and described cylindrical shell and cover junction surface are a scarp; Cover top is provided with opening for feed, and opening for feed covers half, cover top cambered surface, and cover bottom is provided with hygrosensor; Another cambered surface of cover top is inserted with heating rod and pH value detector, and described heating rod and pH value detector all extend in cylindrical shell; Also be provided with whipping appts in cylindrical shell, be provided with resin isolation screen cloth below described whipping appts, described cylinder body bottom center is also provided with liquid outlet.The technical program is by setting up hygrosensor and pH value detector, the wash-out environment in resin elution device can be monitored in real time, and directly it is heated by heating rod, make in resin elution device and remain good wash-out environment, improve elution efficiency; The bonding surface of cylindrical shell and cover is set to inclined-plane, expands the surface-area of cover, leave a larger opening for feed, conveniently can reclaim resin from opening for feed, the difficulty that the resin of inwall attachment cleans also is reduced greatly; Set up thermal insulation layer, make the temperature in resin elution device can keep the constant of long period, be beneficial to the elution process of resin.
In order to realize the utility model better, further, described drum surface is also provided with thermal insulation layer.
In order to realize the utility model better, further, described cylindrical shell and cover are sealed by tongued and grooved flanges.
In order to realize the utility model better, further, described whipping appts comprises the stirring rake of bottom and the stirring motor on top, is fixedly connected with between stirring rake with stirring motor by transmission shaft.
In order to realize the utility model better, further, described stirring rake is two groups, and often organizing stirring rake has two blades, and blade is anchor formula stirring rake, and blade with transmission shaft axisymmetricly, and two groups of stirring rakes are arrange up and down on transmission shaft.Set up two groups of stirring rakes, and each blade of stirring rake is made anchor formula stirring rake, in whipping process, considerably increase the area of stirring, and establish upper and lower two groups of stirring rakes, in whipping process, can agitating resin uniformly, heparin is better separated out from resin.
In order to realize the utility model better, further, described opening for feed is also provided with sealing cover, and described sealing cover comprises decorative cover, is provided with toughened glass in decorative cover, and decorative cover side is provided with handle.Lid sealing cover, establishes toughened glass in decorative cover, can when covered, the elution profile of the heparin of observing device inside, in order to determine the degree of wash-out, thus determines how to take out elutriant.
The utility model compared with prior art, has the following advantages and beneficial effect:
(1) the utility model is by setting up hygrosensor and pH value detector, the wash-out environment in resin elution device can be monitored in real time, and directly it is heated by heating rod, make in resin elution device and remain good wash-out environment, improve elution efficiency;
(2) the utility model is by being set to inclined-plane by the bonding surface of cylindrical shell and cover, expand the surface-area of cover, leave a larger opening for feed, conveniently can reclaim resin from opening for feed, the difficulty that the resin of inwall attachment cleans also is reduced greatly;
(3) the utility model is by setting up thermal insulation layer, makes the temperature in resin elution device can keep the constant of long period, is beneficial to the elution process of resin;
(4) the utility model structure is simple, and vibrational power flow is reasonable especially, is suitable for applying.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model.
Wherein: 1-cylindrical shell, 2-cover, 3-opening for feed, 4-whipping appts, 5-resin isolation screen cloth, 6-heating rod, 7-pH value detector, 8-hygrosensor, 9-thermal insulation layer, 10-liquid outlet.
Embodiment
Be described below in detail embodiment of the present utility model, the example of described embodiment is shown in the drawings, and wherein same or similar label represents same or similar element or has element that is identical or similar functions from start to finish.Being exemplary below by the embodiment be described with reference to the drawings, only for explaining the utility model, and can not being interpreted as restriction of the present utility model.
In description of the present utility model, it should be noted that, unless otherwise clearly defined and limited, term " installation ", " being connected ", " connection " should be interpreted broadly, and such as, can be fixedly connected with, also can be removably connect, or connect integratedly; Can be mechanical connection, also can be electrical connection; Also can be directly be connected, also can be indirectly be connected by intermediary, can be the connection of two element internals.For the ordinary skill in the art, particular case the concrete meaning of above-mentioned term in the utility model can be understood.
Embodiment:
The primary structure of the present embodiment, as shown in Figure 1, comprises the cylindroid cylindrical shell 1 of bottom, and the cover 2 matched with cylindrical shell 1, and described cylindrical shell 1 is a scarp with cover 2 junction surface; Cover 2 top is provided with opening for feed 3, and opening for feed 3 covers cover 2 half, top cambered surface, and cover 2 bottom is provided with hygrosensor 8; Another cambered surface of cover 2 top is inserted with heating rod 6 and pH value detector 7, and described heating rod 6 all extends in cylindrical shell 1 with pH value detector 7; Also be provided with whipping appts 4 in cylindrical shell 1, be provided with resin isolation screen cloth 5 below described whipping appts 4, described cylindrical shell 1 bottom centre is also provided with liquid outlet 10.
Wherein, described cylindrical shell 1 surface is also provided with thermal insulation layer 9, described cylindrical shell 1 is sealed by tongued and grooved flanges with cover 2, described whipping appts 4 comprises the stirring rake of bottom and the stirring motor on top, be fixedly connected with by transmission shaft between stirring rake with stirring motor, described stirring rake is two groups, often organize stirring rake and have two blades, blade is anchor formula stirring rake, and blade with transmission shaft axisymmetricly, two groups of stirring rakes are arrange up and down on transmission shaft, described opening for feed 3 is also provided with sealing cover, described sealing cover comprises decorative cover, toughened glass is provided with in decorative cover, decorative cover side is provided with handle.
The specific works process of the present embodiment: cylindrical shell 1 is engaged with cover 2, use tongued and grooved flanges seals, open the sealing cover at opening for feed 3 place, reaction mass is added in cylindrical shell 1 from opening for feed 3, by handle by seal cap sealing, in whipping appts 4, stirring motor drives stirring rake to rotate stirring by transmission shaft, the toughened glass that can pass through in decorative cover is observed in washing device, the elution profile of heparin, and Real Time Observation pH value detector 7 and hygrosensor 8, by heating rod 6 and the mode adding soda acid material at opening for feed 3, temperature in washing device and pH value are remained on best elute effect.After wash-out completes, open liquid outlet 10, collect elutriant, resin is stayed washing device top by resin isolation screen cloth 5, carry out secondary wash-out at use salt solution, again reclaim elutriant, open sealing cover, resin is taken out from upper feed inlet 3, by clean water, recycles.
After end, by observing the mobility of product in the toughened glass observing response still in decorative cover, if mobility is large, then flows out product by the liquid outlet 10 of bottom, if mobility is little, then opening sealing cover by handle, taking out reaction product from opening for feed 3.
Be understandable that, according to the resin elution structure of the utility model embodiment, principle of work and the working process of the such as parts such as whipping appts 4 and resin isolation screen cloth 5 are all prior aries, and known by those skilled in the art, are just no longer described in detail here.
Although illustrate and described embodiment of the present utility model, those having ordinary skill in the art will appreciate that: do not departing under principle of the present utility model and aim and can carry out multiple change, amendment, replacement and modification to these embodiments, scope of the present utility model is by claim and equivalents thereof.
Claims (6)
1. for a device for resin elution in heparin leaching process, it is characterized in that: the cylindroid cylindrical shell (1) comprising bottom, and the cover (2) matched with cylindrical shell (1), described cylindrical shell (1) and cover (2) junction surface are a scarp; Cover (2) top is provided with opening for feed (3), and opening for feed (3) covers cover (2) half, top cambered surface, and cover (2) bottom is provided with hygrosensor (8); Another cambered surface of cover (2) top is inserted with heating rod (6) and pH value detector (7), and described heating rod (6) and pH value detector (7) all extend in cylindrical shell (1); Also be provided with whipping appts (4) in cylindrical shell (1), described whipping appts (4) below is provided with resin isolation screen cloth (5), and described cylindrical shell (1) bottom centre is also provided with liquid outlet (10).
2. a kind of device for resin elution in heparin leaching process according to claim 1, is characterized in that: described cylindrical shell (1) surface is also provided with thermal insulation layer (9).
3. a kind of device for resin elution in heparin leaching process according to claim 1 and 2, is characterized in that: described cylindrical shell (1) and cover (2) are sealed by tongued and grooved flanges.
4. a kind of device for resin elution in heparin leaching process according to claim 1 and 2, it is characterized in that: described whipping appts (4) comprises the stirring rake of bottom and the stirring motor on top, is fixedly connected with between stirring rake with stirring motor by transmission shaft.
5. a kind of device for resin elution in heparin leaching process according to claim 4, it is characterized in that: described stirring rake is two groups, often organize stirring rake and have two blades, blade is anchor formula stirring rake, and blade with transmission shaft axisymmetricly, two groups of stirring rakes are arrange up and down on transmission shaft.
6. a kind of device for resin elution in heparin leaching process according to claim 1 and 2, is characterized in that: described opening for feed (3) is also provided with sealing cover, and described sealing cover comprises decorative cover, is provided with toughened glass in decorative cover, and decorative cover side is provided with handle.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201520163822.1U CN204490778U (en) | 2015-03-23 | 2015-03-23 | A kind of device for resin elution in heparin leaching process |
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CN201520163822.1U CN204490778U (en) | 2015-03-23 | 2015-03-23 | A kind of device for resin elution in heparin leaching process |
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CN204490778U true CN204490778U (en) | 2015-07-22 |
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CN201520163822.1U Expired - Fee Related CN204490778U (en) | 2015-03-23 | 2015-03-23 | A kind of device for resin elution in heparin leaching process |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108546307A (en) * | 2018-03-01 | 2018-09-18 | 戴永俊 | A kind of heparin sodium production elution tank of layering charging |
CN113230300A (en) * | 2021-05-26 | 2021-08-10 | 邵阳学院 | Method for extracting total flavone content in honeysuckle distillation residual liquid |
-
2015
- 2015-03-23 CN CN201520163822.1U patent/CN204490778U/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108546307A (en) * | 2018-03-01 | 2018-09-18 | 戴永俊 | A kind of heparin sodium production elution tank of layering charging |
CN113230300A (en) * | 2021-05-26 | 2021-08-10 | 邵阳学院 | Method for extracting total flavone content in honeysuckle distillation residual liquid |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150722 Termination date: 20160323 |
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CF01 | Termination of patent right due to non-payment of annual fee |