CN204468043U - Non-moving type near infrared imaging device - Google Patents

Non-moving type near infrared imaging device Download PDF

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Publication number
CN204468043U
CN204468043U CN201520010847.8U CN201520010847U CN204468043U CN 204468043 U CN204468043 U CN 204468043U CN 201520010847 U CN201520010847 U CN 201520010847U CN 204468043 U CN204468043 U CN 204468043U
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Prior art keywords
laser
mainframe box
probe
imaging
camera
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CN201520010847.8U
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Chinese (zh)
Inventor
翟俊辉
许波
艾俊殊
周汉明
宋志祥
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Huijia Biological Instrument (shanghai) Co Ltd
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Huijia Biological Instrument (shanghai) Co Ltd
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Abstract

This utility model belongs to medical imaging apparatus field, relate to a kind of non-moving type near infrared imaging device, primarily of probe, mainframe box and computer composition, probe is arranged on mainframe box inside, and connecting mainframe box by cable, mainframe box connects computer by data wire.This utility model can be advantageously used in near-infrared fluorescence imaging, and mainframe box carries darkroom, can realize quick detection and positioning deep tumor, blood vessel etc. under noinvasive prerequisite by conventional contrast agents.

Description

Non-moving type near infrared imaging device
Technical field
This utility model belongs to medical imaging apparatus field, relates generally to a kind of non-moving type near infrared imaging device, particularly utilizes near-infrared fluorescence imaging technology and the Table top type imaging device designed.
Background technology
Near infrared imaging is also known as fluorescence imaging, and fluorescence imaging needs external light source to excite fluorescent marker in organism, thus obtains signal of video signal.Fluorescent marker is called fluorophor, and the electron outside nucleus of fluorophor is subject to after photon excitation can from ground state transition to high energy excited state, and the electronics that be in excited state is unstable, can spontaneous transition to ground state, and give off the photon of specific wavelength.This part photon given off due to energy level transition, through the absorption of biological tissue and scattering, is finally caught and amplification by highly sensitive optical detector, and imaging after computer acquisition process, the ultimate principle of Here it is fluorescence imaging.
Although Imaging-PAM achieves good clinical improvement, the treatment such as tumor operation is also faced with many-sided difficulty in actual application.At present when carrying out some associated treatment, a kind of not perfect surgery planning method; Doctor is difficult to exactly intervention therapeutic apparatus is punctured to tumor locus according to predetermined operation plan.Conventional fluorescence imaging device obtains picture signal by increasing sensor, but resolution is low; And single-sensor imaging easily produces correction of motion artefacts.Therefore expect that providing a kind of neither damages the near-infrared real-time imaging devices that image resolution ratio does not introduce again correction of motion artefacts.
Summary of the invention
Goal of the invention
This utility model relates to a kind of non-moving type near infrared imaging device, and this device can be advantageously used in near-infrared fluorescence imaging, and mainframe box carries darkroom, can realize quick detection and positioning deep tumor, blood vessel etc. under noinvasive prerequisite by conventional contrast agents.
Technical scheme
A kind of non-moving type near infrared imaging device, primarily of probe, mainframe box and computer composition, is characterized in that: probe is arranged on mainframe box inside, and connects mainframe box by cable, and mainframe box connects computer by data wire; It is inner that high-sensitivity camera, laser emitting window and LED light source are integrated in probe; High-sensitivity camera is arranged on the central shaft of probe, is provided with LED light source below high-sensitivity camera, and high-sensitivity camera side is provided with laser emitting window; Mainframe box comprises Imaging laser, power suppling part divides and mainboard, Imaging laser divides with power suppling part and is all connected mainboard, LED control circuit, Imaging laser control circuit, camera control and data transmission circuit are integrated on mainboard, and power suppling part is divided into Imaging laser, LED control circuit, Imaging laser control circuit, camera control and data transmission circuit to power; High-sensitivity camera connects camera control and data transmission circuit by USB data line, and laser emitting window is by Fiber connection Imaging laser, and Imaging laser connects into picture laser control circuit, and LED light source connects LED control circuit; In mainframe box, the below of probe is that position placed by sample.
The front of high-sensitivity camera is provided with optical filter.
LED light source is 6 LED of the distribution in regular hexagon.
Laser emitting window totally three, two connect Imaging laser, and one is window for subsequent use, and three rounded distributions of window, angle of being separated by is 120 degree.
Power suppling part divides and comprises 24V DC source and main power switch, and 24V DC source is connected on 220V power supply by main power switch.
Advantage and effect
(1) equipment excitation wavelength can according to the difference of generating laser, and the highest excitation wavelength of adjustment, respectively to 695nm, 795nm;
(2) interference of other media can be got rid of, as blood, blood vessel, muscle etc., imaging clearly;
(3) structure is novel, and movable operation, is convenient to realtime imaging in art;
(4) non-intervention type imaging, based on skin, blood vessel, biological tissue near infrared ray reflective degree difference, device relies on high-resolution, highly sensitive feature, realizes non-intervention type imaging;
(5) mainframe box carries darkroom, and capacity of resisting disturbance is strong.
Accompanying drawing explanation
Fig. 1 is this utility model probe and mainframe box connection diagram;
Fig. 2 is this utility model structural representation;
Fig. 3 is probe front-end view.
Description of reference numerals:
0. probe, 1. high-sensitivity camera, 2. laser emitting window, 3.LED light source, 4. computer, 5. mainframe box, 6. optical filter, 7. optical fiber, 8. USB data line, 9. mainboard, 10. main power switch, position placed by 11. samples.
detailed description of the invention:
Below in conjunction with accompanying drawing, this utility model is described further:
The utility model proposes a kind of non-moving type near infrared imaging device, as depicted in figs. 1 and 2, primarily of probe, mainframe box and computer composition, it is characterized in that: it is inner that probe 0 is arranged on mainframe box 5, probe is integrated into the interference that external condition can be completely free of in mainframe box inside, reduce the impact that extraneous light produces image quality as much as possible, and pop one's head in and 0 connect mainframe box 5 by the cable of convenient plug, mainframe box 5 connects computer 4 by data wire; It is inner that high-sensitivity camera 1, laser emitting window 2 and LED light source 3 are integrated in probe 0; High-sensitivity camera 1 is arranged on the central shaft of probe 0, is provided with LED light source 3 below high-sensitivity camera 1, and high-sensitivity camera 1 side is provided with laser emitting window 2; Mainframe box 5 comprises Imaging laser, power suppling part divides and mainboard 9, Imaging laser and power suppling part divide and are all connected mainboard 9, LED control circuit, Imaging laser control circuit, camera control and data transmission circuit are integrated on mainboard 9, and power suppling part is divided into Imaging laser, LED control circuit, Imaging laser control circuit, camera control and data transmission circuit to power; High-sensitivity camera 1 connects camera control and data transmission circuit by USB data line 8, and laser emitting window 2 connects Imaging laser by optical fiber 7, and Imaging laser connects into picture laser control circuit, and LED light source 3 connects LED control circuit; The below of mainframe box 5 inside probe is provided with sample and places position 11, for placing detected sample.
Optical filter 6 is also provided with in the front of high-sensitivity camera 1.
LED light source 3 is 6 LED of the distribution in regular hexagon.
Power suppling part divides and comprises 24V DC source and main power switch 10,24V DC source is connected on 220V power supply by main power switch 10.
In addition, picture, video generates and the reception etc. of equipment operating instruction is then completed by computer.
1. pop one's head in
Probe is one of pith of the present utility model, and it has gathered LED light source, optical filter, high-sensitivity camera and laser emitting window.LED light source provides white-light illuminating in operation process, this white-light illuminating is different from common white light, its optical wavelength mainly concentrates on visible light part, between near infrared region, the light accounting of (more than 700nm) is minimum, the function of optical filter is then filtered out by the light being less than certain wavelength, therefore the light produced for this LED light source of testing illumination can not affect the fluorescence next produced by laser excitation, can use up the minimizing light interference of maximum like this.
The function of high-sensitivity camera gathers the fluorescence signal received, for common CCD, this extremely weak fluorescence signal cannot be collected, because there is no enough sensitivity, then this part signal can be collected efficiently for highly sensitive camera, the signal collected is transferred to mainframe box by USB data line, and has Host Transfer to arrive computer system, completes work for the treatment of.
The function of laser emitting window disperses out uniformly by the laser produced by laser instrument, and laser emitting window installs (angle of inclination is with 60-80 degree) along probe inclined bottom surface certain angle, and the laser of outgoing can be allowed like this to be radiated at uniformly by product in the same old way.In this utility model, laser emitting window one has 3, and wherein derive module for installing laser for two, another one is then for window for subsequent use.Three rounded distributions of window, angle of being separated by is 120 degree, and specific design pattern is see Fig. 3.
2. mainframe box
Mainframe box comprises that power suppling part divides, laser instrument, mainboard (mainboard comprises Imaging laser control circuit, LED control circuit, camera control and data transmission circuit) etc., wherein power suppling part divides primary responsibility to convert 220V room electricity to 24V unidirectional current, then supplies all parts and uses.Laser instrument is then used to produce laser, then probe is transmitted through the fiber to, this utility model can adopt the laser instrument of two cover different wave lengths to replace as required and use, a set of is 695nm laser instrument, another set of, be 795nm laser instrument, the wavelength that optical filter in probe filters is slightly less than 695nm, can ensure that most of fluorescence excited by 695nm laser instrument is by this optical filter, then arrives high-sensitivity camera like this.LED is installed on probe front end, and the control circuit of LED receives control instruction---the ON/OFF from system, and Imaging laser control circuit also receives control instruction from computer to realize the Push And Release of laser instrument.The function mainly various signal of Coordination Treatment and the data of mainboard, they are distributed to each assembly, also feed back some system current states simultaneously, whether such as LED opens, whether laser instrument is opened, these feedback fractions with display lamp dark/going out shows, to point out the current state of user equipment.
3. connection cable
Probe is connected by cable with between mainframe box, probe is arranged at the centre of mainframe box inside, cable all can be concentrated in mainframe box, do not take space outerpace, save length of cable, both comprised LED supply line in this cable, CCD transmits data wire, also comprise optical fiber simultaneously, cable one end is fixing with probe, and the other end is then connected with mainframe box with the form of convenient plug-in type plug.
Main working process of the present utility model is:
A. system prepares: after equipment exact connect ion, open the main power switch after mainframe box, installation operating system in a computer can be opened after System self-test terminates, mainframe box separately there is the switch of a unlatching laser instrument, whether this switch can be opened for controlling laser instrument, only when this switch is in opening, just by computer or the laser button be attached on probe, laser instrument is opened, this design is mainly used in ensureing use safety, reduce the unexpected open operation of laser instrument, although the laser instrument used in this utility model belongs to Class1 class, namely be safe to people, there is no biological harm, but still keep the principle with better safe than sorry in this utility model, arrange laser to open and must be operated by two steps.
B. Camera camera is opened: the time of system is about 1 ~ 2min, therefore, can be open at the laser switch on mainframe box after such time, now, by opening computer system, then Camera being opened, the image of display can be seen at display screen.
C. laser instrument is opened: unlatching laser instrument button or the direct Laser button pressed on probe of clicking computer system can open laser instrument, now the sample injecting the contrast agent such as suitable ICG is placed in probe front certain distance and can collects imaging results clearly.Carry out moving distribution because these contrast agent can follow blood, therefore can with seeing stronger brightness in the region that blood is relatively concentrated, the picture therefore by demonstrating, can see vessel branch network or tumor etc. clearly.
Because this equipment does not in use have space constraint, and because of it, there is the feature of sensitivity, fine definition, therefore the characteristic such as blood vessel or tumor can be shown, therefore in operation process, there is navigation feature, namely instruct doctor to carry out tumor resection, vascular suture etc. operation.
Utility model works principle is as follows:
This utility model utilizes near-infrared laser fluorescence excitation dyestuff, is received again, then carry out data receiver and work for the treatment of via computer, finally obtain the imaging data of fluorescence excitation by optical filter after being filtered by high-sensitivity camera (Camera).

Claims (5)

1. a non-moving type near infrared imaging device, primarily of probe, mainframe box and computer composition, it is characterized in that: it is inner that probe (0) is arranged on mainframe box (5), and connect mainframe box (5) by cable, and mainframe box (5) connects computer (4) by data wire; It is inner that high-sensitivity camera (1), laser emitting window (2) and LED light source (3) are integrated in probe (0); High-sensitivity camera (1) is arranged on the central shaft of probe (0), and high-sensitivity camera (1) below is provided with LED light source (3), and high-sensitivity camera (1) side is provided with laser emitting window (2); Mainframe box (5) comprises Imaging laser, power suppling part divides and mainboard (9), Imaging laser and power suppling part divide and are all connected mainboard (9), LED control circuit, Imaging laser control circuit, camera control and data transmission circuit are integrated on mainboard (9), and power suppling part is divided into Imaging laser, LED control circuit, Imaging laser control circuit, camera control and data transmission circuit to power; High-sensitivity camera (1) connects camera control and data transmission circuit by USB data line (8), laser emitting window (2) connects Imaging laser by optical fiber (7), Imaging laser connects into picture laser control circuit, and LED light source (3) connects LED control circuit; In mainframe box (5), the below of probe is that position (11) placed by sample.
2. non-moving type near infrared imaging device according to claim 1, is characterized in that: the front of high-sensitivity camera (1) is provided with optical filter (6).
3. non-moving type near infrared imaging device according to claim 1, is characterized in that: LED light source (3) is 6 LED of the distribution in regular hexagon.
4. non-moving type near infrared imaging device according to claim 1, is characterized in that: laser emitting window (2) totally three, and two connect Imaging laser, and one is window for subsequent use, and three rounded distributions of window, angle of being separated by is 120 degree.
5. non-moving type near infrared imaging device according to claim 1, is characterized in that: power suppling part divides and comprises 24V DC source and main power switch (10), and 24V DC source is connected on 220V power supply by main power switch (10).
CN201520010847.8U 2015-01-08 2015-01-08 Non-moving type near infrared imaging device Active CN204468043U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104605818A (en) * 2015-01-08 2015-05-13 汇佳生物仪器(上海)有限公司 Non-movable infrared imaging device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104605818A (en) * 2015-01-08 2015-05-13 汇佳生物仪器(上海)有限公司 Non-movable infrared imaging device
CN104605818B (en) * 2015-01-08 2017-02-01 汇佳生物仪器(上海)有限公司 Non-movable infrared imaging device

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