CN204454960U - A kind of efficient collagen protein filtration unit - Google Patents

A kind of efficient collagen protein filtration unit Download PDF

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Publication number
CN204454960U
CN204454960U CN201520115525.XU CN201520115525U CN204454960U CN 204454960 U CN204454960 U CN 204454960U CN 201520115525 U CN201520115525 U CN 201520115525U CN 204454960 U CN204454960 U CN 204454960U
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filter
collagen
efficiency
decarburization
filter device
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冯俊超
司丽荣
贾海亮
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HEBEI COLLAGEN BIOTECHOLOGY CO LD
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HEBEI COLLAGEN BIOTECHOLOGY CO LD
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Abstract

本实用新型公开了一种高效胶原蛋白过滤装置,包括溶解机构、过滤装置、分离装置、超滤装置和脱碳装置,所述溶解机构、过滤装置、分离装置、超滤装置和脱碳装置皆通过设置的管线进行依次连接,所述溶解机构内设有搅拌装置,所述溶解机构与过滤装置之间设有离心机,所述管线内设有水泵,所述水泵设有一个以上,所述分离装置内设有过滤膜,所述脱碳装置内设有若干过滤布,所述各个过滤布之间设有过滤孔,所述过滤装置内设有圆环和凹槽,所述圆环设有一个以上,所述圆环在过滤装置的内壁上依次排列,所述凹槽位于过滤装置的上下两端;该高效胶原蛋白过滤装置结构简单,质量较佳,效果较好。

The utility model discloses a high-efficiency collagen filter device, which comprises a dissolution mechanism, a filter device, a separation device, an ultrafiltration device and a decarburization device. Sequentially connected through the provided pipelines, a stirring device is provided in the dissolving mechanism, a centrifuge is provided between the dissolving mechanism and the filtering device, a water pump is provided in the pipeline, and more than one water pump is provided. A filter membrane is provided in the separation device, a number of filter cloths are provided in the decarburization device, filter holes are provided between the filter cloths, a ring and a groove are provided in the filter device, and the ring is provided with There is more than one, the rings are arranged sequentially on the inner wall of the filter device, and the grooves are located at the upper and lower ends of the filter device; the high-efficiency collagen filter device has simple structure, better quality and better effect.

Description

一种高效胶原蛋白过滤装置A high-efficiency collagen filter device

技术领域 technical field

本实用新型涉及一种高效胶原蛋白过滤装置。 The utility model relates to a high-efficiency collagen filter device.

背景技术 Background technique

胶原蛋白是世界上应用最为广泛的生物材料,目前国际年产量在 2 万吨左右。在医学领域,胶原蛋白作为高生物相容性、高生物活性材料被广泛应用于创伤控制和转化医学。2011年,国际著名的商务测评机构Frost & Sullivan的市场调研数据也表明,胶原蛋白已经成为最有市场竞争力的生物医学材料,用于再生医学,并将进一步发展,成为器官替代医学两大材料之一,其技术就绪水平——Technology readiness level (TRL) 评分为 8(最高 9)。美国医药食品管理局(FDA)预测,到2015年胶原蛋白将占有超过20%的生物医学材料市场,年销售额超过200亿美元。 Collagen is the most widely used biomaterial in the world, and the current international annual output is about 20,000 tons. In the medical field, collagen, as a highly biocompatible and highly bioactive material, is widely used in wound control and translational medicine. In 2011, the market research data of Frost & Sullivan, an internationally renowned business evaluation agency, also showed that collagen has become the most competitive biomedical material for regenerative medicine, and will further develop to become the two major materials of organ replacement medicine One, its technology readiness level - Technology readiness level (TRL) score is 8 (out of 9). The US Food and Drug Administration (FDA) predicts that collagen will occupy more than 20% of the biomedical materials market by 2015, with annual sales exceeding $20 billion.

一直以来,胶原蛋白主要从动物的组织器官提取,如猪牛的皮、骨骼和筋腱等。近年来,国际大型企业开始着手开发合成胶原蛋白及其类似物的研发,但受合成技术限制,水平较低,产量有限,价格昂贵(目前市面合成高纯度胶原蛋白的售价高达 3000 美元 / 毫克),仅能用于科研应用。 For a long time, collagen is mainly extracted from animal tissues and organs, such as pig and cow skin, bones and tendons. In recent years, large international companies have begun to develop synthetic collagen and its analogues, but limited by synthetic technology, the level is low, the output is limited, and the price is expensive (currently, the price of synthetic high-purity collagen in the market is as high as 3,000 US dollars / mg ), for scientific applications only.

目前国内制备胶原蛋白的装置较少,且多采用酸解法进行制备,胶原蛋白质量较低,且效果较差。 At present, there are few devices for preparing collagen in China, and most of them are prepared by acid hydrolysis. The quality of collagen is low and the effect is poor.

实用新型内容 Utility model content

本实用新型所要解决的技术问题在于提供一种具有结构简单,质量较佳,效果较好的高效胶原蛋白过滤装置。 The technical problem to be solved by the utility model is to provide a high-efficiency collagen filter device with simple structure, better quality and better effect.

为解决上述问题,本实用新型采用如下技术方案: In order to solve the above problems, the utility model adopts the following technical solutions:

一种高效胶原蛋白过滤装置,包括溶解机构、过滤装置、分离装置、超滤装置和脱碳装置,所述溶解机构、过滤装置、分离装置、超滤装置和脱碳装置皆通过设置的管线进行依次连接,所述溶解机构内设有搅拌装置,所述溶解机构与过滤装置之间设有离心机,所述管线内设有水泵,所述水泵设有一个以上,所述分离装置内设有过滤膜,所述脱碳装置内设有若干过滤布,所述各个过滤布之间设有过滤孔,所述过滤装置内设有圆环和凹槽,所述圆环设有一个以上,所述圆环在过滤装置的内壁上依次排列,所述凹槽位于过滤装置的上下两端。 A high-efficiency collagen filtration device, including a dissolution mechanism, a filtration device, a separation device, an ultrafiltration device and a decarburization device, and the dissolution mechanism, filtration device, separation device, ultrafiltration device and decarburization device are all carried out through the provided pipeline connected in turn, the dissolving mechanism is provided with a stirring device, a centrifuge is provided between the dissolving mechanism and the filtering device, a water pump is provided in the pipeline, and more than one water pump is provided, and the separation device is provided with filter membrane, the decarburization device is provided with a number of filter cloths, filter holes are provided between the filter cloths, rings and grooves are provided in the filter device, and more than one ring is provided, so The circular rings are arranged sequentially on the inner wall of the filter device, and the grooves are located at the upper and lower ends of the filter device.

作为优选,所述溶解机构为溶解罐。 Preferably, the dissolution mechanism is a dissolution tank.

作为优选,所述分离装置内设有紫外线检测器,进行紫外线检测。 Preferably, an ultraviolet detector is provided in the separation device for ultraviolet detection.

作为优选,所述超滤装置下部设有排液管线,排出多余液体。 Preferably, a drain line is provided at the lower part of the ultrafiltration device to drain excess liquid.

作为优选,所述各个圆环之间的间隙为0.1mm,也可根据情况调整。 Preferably, the gap between the rings is 0.1mm, which can also be adjusted according to the situation.

本实用新型的有益效果是:由于设置有溶解机构、过滤装置、分离装置、超滤装置和脱碳装置,提高了胶原蛋白的萃取率,制备过程中不易带入杂菌从而减少了污染,提高了产品的品质,同时采用了多个过滤机构,过滤机构结构简单,成本较低,脱碳效果好,杂质少。 The beneficial effects of the utility model are: the extraction rate of collagen is improved due to the dissolving mechanism, the filtering device, the separating device, the ultrafiltration device and the decarburization device, and the miscellaneous bacteria are not easy to be brought into the preparation process, thereby reducing pollution and improving The quality of the product is guaranteed, and multiple filter mechanisms are adopted at the same time. The filter mechanism has a simple structure, low cost, good decarbonization effect, and less impurities.

附图说明 Description of drawings

图1为本实用新型一种高效胶原蛋白过滤装置的整体结构图。 Fig. 1 is an overall structural diagram of a high-efficiency collagen filter device of the present invention.

具体实施方式 Detailed ways

参阅图1所示,一种高效胶原蛋白过滤装置,包括溶解机构1、过滤装置2、分离装置3、超滤装置4和脱碳装置5,所述溶解机构1、过滤装置2、分离装置3、超滤装置4和脱碳装置5皆通过设置的管线12进行依次连接,所述溶解机构1内设有搅拌装置6,所述溶解机构1与过滤装置2之间设有离心机7,所述管线12内设有水泵8,所述水泵8设有一个以上,所述分离装置3内设有过滤膜(未图示),所述脱碳装置5内设有若干过滤布(未图示),所述各个过滤布之间设有过滤孔(未图示),所述过滤装置2内设有圆环9和凹槽10,所述圆环9设有一个以上,所述圆环9在过滤装置2的内壁上依次排列,所述凹槽10位于过滤装置2的上下两端。 Referring to Fig. 1, a high-efficiency collagen filtration device includes a dissolution mechanism 1, a filtration device 2, a separation device 3, an ultrafiltration device 4 and a decarburization device 5, and the dissolution mechanism 1, the filtration device 2, and the separation device 3 , the ultrafiltration device 4 and the decarburization device 5 are connected in sequence through the provided pipeline 12, the stirring device 6 is arranged in the dissolving mechanism 1, and the centrifuge 7 is arranged between the dissolving mechanism 1 and the filtering device 2, so The pipeline 12 is provided with a water pump 8, the water pump 8 is provided with more than one, the separation device 3 is provided with a filter membrane (not shown), and the decarbonization device 5 is provided with a number of filter cloths (not shown). ), filter holes (not shown) are provided between the filter cloths, rings 9 and grooves 10 are provided in the filter device 2, more than one ring 9 is provided, and the ring 9 Arranged in sequence on the inner wall of the filter device 2 , the grooves 10 are located at the upper and lower ends of the filter device 2 .

所述溶解机构1为溶解罐,也可替换为其他具有等效的容纳机构。 The dissolution mechanism 1 is a dissolution tank, which can also be replaced with other equivalent accommodation mechanisms.

所述分离装置3内设有紫外线检测器(未图示)。 An ultraviolet detector (not shown) is installed in the separation device 3 .

所述超滤装置4下部设有排液管线11,进行排液。 The bottom of the ultrafiltration device 4 is provided with a drain line 11 for draining.

所述各个圆环9之间的间隙为0.1mm,也可根据情况调整。 The gap between the various rings 9 is 0.1 mm, which can also be adjusted according to the situation.

本实用新型的有益效果是:由于设置有溶解机构、过滤装置、分离装置、超滤装置和脱碳装置,提高了胶原蛋白的萃取率,制备过程中不易带入杂菌从而减少了污染,提高了产品的品质,同时采用了多个过滤机构,过滤机构结构简单,成本较低,脱碳效果好,杂质少。 The beneficial effects of the utility model are: the extraction rate of collagen is improved due to the arrangement of dissolving mechanism, filter device, separation device, ultrafiltration device and decarburization device, and it is not easy to bring in miscellaneous bacteria in the preparation process, thereby reducing pollution and improving The quality of the product is guaranteed, and multiple filter mechanisms are adopted at the same time. The filter mechanism has a simple structure, low cost, good decarbonization effect, and less impurities.

以上所述,仅为本实用新型的具体实施方式,但本实用新型的保护范围并不局限于此,任何不经过创造性劳动想到的变化或替换,都应涵盖在本实用新保护范围为准。 The above is only a specific embodiment of the utility model, but the scope of protection of the utility model is not limited thereto, and any change or replacement that does not go through creative labor should be covered by the scope of protection of the utility model.

Claims (5)

1. 一种高效胶原蛋白过滤装置,其特征在于:包括溶解机构、过滤装置、分离装置、超滤装置和脱碳装置,所述溶解机构、过滤装置、分离装置、超滤装置和脱碳装置皆通过设置的管线进行依次连接,所述溶解机构内设有搅拌装置,所述溶解机构与过滤装置之间设有离心机,所述管线内设有水泵,所述水泵设有一个以上,所述分离装置内设有过滤膜,所述脱碳装置内设有若干过滤布,所述各个过滤布之间设有过滤孔,所述过滤装置内设有圆环和凹槽,所述圆环设有一个以上,所述圆环在过滤装置的内壁上依次排列,所述凹槽位于过滤装置的上下两端。 1. A high-efficiency collagen filter, characterized in that: comprising a dissolving mechanism, a filter, a separation device, an ultrafiltration device and a decarburization device, the dissolution mechanism, a filtration device, a separation device, an ultrafiltration device and a decarburization device They are all connected sequentially through the provided pipelines. A stirring device is provided in the dissolving mechanism, a centrifuge is provided between the dissolving mechanism and the filtering device, a water pump is provided in the pipeline, and more than one water pump is provided. A filter membrane is provided in the separation device, a number of filter cloths are provided in the decarburization device, filter holes are provided between the filter cloths, a ring and a groove are provided in the filter device, and the ring More than one is provided, the rings are arranged in sequence on the inner wall of the filter device, and the grooves are located at the upper and lower ends of the filter device. 2. 根据权利要求1所述的高效胶原蛋白过滤装置,其特征在于:所述溶解机构为溶解罐。 2. The high-efficiency collagen filter device according to claim 1, characterized in that: the dissolution mechanism is a dissolution tank. 3. 根据权利要求1所述的高效胶原蛋白过滤装置,其特征在于:所述分离装置内设有紫外线检测器。 3. The high-efficiency collagen filter device according to claim 1, characterized in that: an ultraviolet detector is arranged in the separation device. 4. 根据权利要求1所述的高效胶原蛋白过滤装置,其特征在于:所述超滤装置下部设有排液管线。 4. The high-efficiency collagen filter device according to claim 1, characterized in that: the bottom of the ultrafiltration device is provided with a drain line. 5. 根据权利要求1所述的高效胶原蛋白过滤装置,其特征在于:所述各个圆环之间的间隙为0.1mm。 5. The high-efficiency collagen filter device according to claim 1, characterized in that: the gap between each of the rings is 0.1mm.
CN201520115525.XU 2015-02-25 2015-02-25 A kind of efficient collagen protein filtration unit Expired - Lifetime CN204454960U (en)

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