CN204428893U - The fluid control apparatus of radial chromatography post - Google Patents
The fluid control apparatus of radial chromatography post Download PDFInfo
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- CN204428893U CN204428893U CN201420796905.XU CN201420796905U CN204428893U CN 204428893 U CN204428893 U CN 204428893U CN 201420796905 U CN201420796905 U CN 201420796905U CN 204428893 U CN204428893 U CN 204428893U
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- control panel
- type guiding
- guiding gutter
- sleeve plate
- water conservancy
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Abstract
The fluid control apparatus of radial chromatography post, comprise control panel, sleeve plate and mozzle, on control panel one end face, regularly row establishes multiple H type guiding gutter, and each H type guiding gutter is longitudinally arranged, and establishes through hole to be communicated to the other end of control panel at the quadripolar corners of each H type guiding gutter; H type guiding gutter is interconnected by " work " font groove lain low, sleeve plate is fitted in control panel and establishes on the end face of H type guiding gutter, mozzle is communicated to H type guiding gutter, it is tubular that sleeve plate and control panel are set to tubular structure after fitting into one, by the spread configuration of H type guiding gutter on control panel, the flow cross-section that liquid stream is passed through to the Distance geometry that each exports by entrance is long-pending completely equal.Liquid flowing resistance is completely equal, ensure that mobile phase transmission time, flow, pressure are consistent.Allow to the liquid current control being applicable to industrial major diameter radial chromatography post, effectively eliminate the residence time of mobile phase on liquid flow sharing system deposits significant differences defect with the increase of radial chromatography column diameter.
Description
Technical field
The utility model belongs to the association area of the liquid flow control technology of radial chromatographic column in pharmaceuticals industry separation and purification system, is specifically to be a kind ofly applicable to the flow direction of mobile phase and the fluid control apparatus of assignment of traffic in large diameter cylindrical shape radial chromatography post.
Background technology
Chromatographic column is the vitals of preparing chromatograph in industry, and major function is separation from liquefied mixture, obtains pure material.In actual production; in order to accelerate the disengaging time of material; improve separative efficiency; preparative chromatography device to enter sample size very large; cause the corresponding increasing of the segregational load of preparative chromatography post; the material that often there will be a large amount of strong absorption remains in separating medium, pollutes chromatography column packing, shortens the service life of chromatographic column.In preparative chromatography device, add radial chromatography post, the material that rejected in advance adsorbs by force is a kind of very effective process.
In use, the liquid flow path direction of radial chromatography post and flow can directly have influence on its effect.Such as: it is improper that shortage controls or controls, and mobile phase by medium in whole post, can cause the waste of medium in post, and the price of this medium is not expensive.
The liquid flow control technology that the radial chromatography post applied in the lab adopts injects mobile phase by the polytetrafluoroethylene sleeve of porous to the separating medium in sintering sieve plate sleeve.But comparatively large for diameter, the especially radial chromatography post of industrial production, above way is difficult to the uniform distribution realizing mobile phase.
Utility model content
The utility model provides a kind of fluid control apparatus of radial chromatography post, it can be applicable to the liquid current control of industrial major diameter radial chromatography post, the residence time of effective elimination mobile phase on liquid flow sharing system has the defect of significant differences with the increase of radial chromatography column diameter, realize the even original allocation entering radial chromatography post interior media mobile phase, and mobile phase high pressure conveying impact can not be subject to.The structural design of this fluid control apparatus is simple, not easily blocks, easily cleaning and Reusability.
The technical scheme in the invention for solving the technical problem is: a kind of fluid control apparatus of radial chromatography post, comprises control panel, sleeve plate and mozzle;
Regularly spread configuration multiple H type guiding gutter on an end face of described control panel, each H type guiding gutter is longitudinally arranged, and arranges at the quadripolar corners of each H type guiding gutter the other end that through hole is communicated to described control panel;
Form a water conservancy diversion module by every four by adjacent H type guiding gutter, and four H type guiding gutters in each water conservancy diversion module are communicated to respective transverse center position by " work " font groove lain low;
Described control panel end face is established eight water conservancy diversion modules altogether, and every mutually by adjacent four water conservancy diversion module compositions one group, and symmetrical about the longitudinal center's broken line on control panel end face;
Four water conservancy diversion modules often in group are communicated to respective transverse center position by " work " font groove lain low;
Cylinder groove is established in the end face center being provided with H type guiding gutter at control panel, and longitudinally establishes two groups of water conservancy diversion modules described in the connection of yi word pattern groove to two ends centered by described cylinder groove;
At the center of described sleeve plate, central through hole is set;
Described sleeve plate is fitted in described control panel establish on an end face of H type guiding gutter, described central through hole is coaxially corresponding with described cylinder groove, and described mozzle one end is connected in described cylinder groove through described central through hole;
Described sleeve plate and described control panel are longitudinally set to tubular and link are sealed after fitting into one and be connected.
Described sleeve plate adopts 316L stainless steel, and described control panel adopts polytetrafluoroethylene (PTFE) material.
The beneficial effects of the utility model are: molding structure of the present utility model is tubular, but takes plane form when fabrication design, reduces manufacture difficulty.By the spread configuration of H type guiding gutter on control panel, after liquid stream is entered by cylinder groove, circulation is carried out longitudinally, horizontal equalization shunting, eventually passes through and arranges that uniform fluid outlet (through hole namely on control panel) is injected in separating medium with identical pressure with identical flow.The flow cross-section that liquid stream passes through from each entrance to the Distance geometry that each exports is long-pending completely equal.Liquid flowing resistance is completely equal, ensure that the mobile phase transmission time, flow, pressure identical.So, it can be applicable to the liquid current control of industrial major diameter radial chromatography post, the residence time of effective elimination mobile phase on liquid flow sharing system has the defect of significant differences with the increase of radial chromatography column diameter, realize the even original allocation entering radial chromatography post interior media mobile phase, and mobile phase high pressure conveying impact can not be subject to.In addition its structural design is simple, not easily blocks, easily cleaning and Reusability.
Accompanying drawing explanation
Fig. 1 is the structural representation of the both ends of the surface of control panel in the utility model;
Fig. 2 is the structural representation of single H type guiding gutter on control panel in the utility model;
Fig. 3 is the status architecture schematic diagram in the utility model in control panel and sleeve plate connection procedure;
Fig. 4 is structural representation when control panel and sleeve plate connect as one in the utility model;
In figure: 1 control panel, 11 H type guiding gutters, 111 cannelures, 12 cylinder grooves, 13 through holes, 2 sleeve plates, 3 mozzles.
Detailed description of the invention
For ease of understanding the technical solution of the utility model, below in conjunction with accompanying drawing, wherein involved technology contents is described further.
To in description of the present utility model, it should be noted that, term "left", "right", " on ", D score, " interior ", the orientation of the instruction such as " outward " or position relationship be based on orientation shown in the drawings or position relationship, only the utility model and simplified characterization for convenience of description, instead of the device of instruction or hint indication or element must have specific orientation, with specific azimuth configuration and operation, therefore can not be interpreted as restriction of the present utility model.
In description of the present utility model, it should be noted that, unless otherwise clearly defined and limited, term " installation ", " being connected ", " connection " should be interpreted broadly, and such as, can be fixedly connected with, also can be removably connect, or connect integratedly; Can be mechanical connection, also can be electrical connection, can be directly to be connected, and also indirectly can be connected by intermediary, can be the connection of two element internals.For the ordinary skill in the art, concrete condition the concrete meaning of above-mentioned term in the utility model can be understood.
As shown in Figures 1 to 4:
A fluid control apparatus for radial chromatography post, comprises control panel 1, sleeve plate 2 and mozzle 3.
Regularly spread configuration 32 H type guiding gutters 11 on an end face of described control panel 1, each H type guiding gutter 11 longitudinally (upward and downward) is arranged, and namely the cannelure 111 of H type guiding gutter 11 extends along the vertical direction.At the quadripolar corners (two ends of each cannelure 111) of each H type guiding gutter 11, the other end that through hole 13 is communicated to described control panel 1 is set.
Form a water conservancy diversion module by every four by adjacent H type guiding gutter 11, and four H type guiding gutters 11 in each water conservancy diversion module are communicated to respective transverse center position by " work " font groove lain low.
Described control panel 1 end face eight water conservancy diversion modules have been established altogether, and it is every mutually by adjacent four water conservancy diversion module compositions one group, and symmetrical about the longitudinal center's broken line on control panel 1 end face, i.e. four water conservancy diversion module compositions one group of upper end, four water conservancy diversion module compositions one group of lower end.
Be communicated to the transverse center position of each water conservancy diversion module by arranging " work " font groove lain low between four water conservancy diversion modules of upper end.In like manner, the same upper end of mode of communicating between four water conservancy diversion modules of lower end.
Cylinder groove 12 is established in the end face center being provided with H type guiding gutter at control panel 1, and longitudinally establishes the two groups of water conservancy diversion modules being positioned at upper and lower end described in the connection of yi word pattern groove to two ends centered by described cylinder groove 12.
Arrange central through hole at the center of described sleeve plate 2, described sleeve plate adopts 316L stainless steel.
Described control panel 1 adopts polytetrafluoroethylene (PTFE) material.
Described sleeve plate 2 is fitted in described control panel 1 establish on an end face of H type guiding gutter 11, the end of Yao Shi edge and grooved upper end all seals laminating, thus makes each H type guiding gutter 11 and each H type guiding gutter communication groove each other form seal groove.Described central through hole is coaxial corresponding with described cylinder groove 12, and described mozzle 3 one end is connected in described cylinder groove 12 through described central through hole.Finally, be longitudinally set to tubular (namely the girth of tubular equals the longitudinal length of sleeve plate 2 or control panel 1) and link is sealed after described sleeve plate 2 and described control panel 1 being fitted into one and be connected.After liquid is entered by this cylindrical body, cylinder groove 12 place entered on described control panel 1 through described mozzle 3 starts once to shunt, as shown in Figure 1, stream two is punished by cylinder groove 12, enter in upper and lower two groups of H type guiding gutters 11, second diffluence is carried out in both sides to the left and right, finally carrying out three shuntings again enters in each independently water conservancy diversion module, each independently H type guiding gutter 11 is entered carrying out twice shunting in an independently water conservancy diversion module, the flow direction in H type guiding gutter 11 as shown in Figure 2, finally flowed out by the through hole 13 on H type guiding gutter 11, be injected in separating medium with identical pressure with identical flow.The flow cross-section that the Distance geometry that liquid stream exports from cylinder groove 12 porch to each through hole 13 passes through is long-pending completely equal.Liquid flowing resistance is also completely equal, ensure that the mobile phase transmission time, flow, pressure identical.So, it can be applicable to the liquid current control of industrial major diameter radial chromatography post, the residence time of effective elimination mobile phase on liquid flow sharing system has the defect of significant differences with the increase of radial chromatography column diameter, realize the even original allocation entering radial chromatography post interior media mobile phase, and mobile phase high pressure conveying impact can not be subject to.In addition its structural design is simple, not easily blocks, easily cleaning and Reusability.
The above is only preferred embodiment of the present utility model; should be understood that; for those skilled in the art; under the prerequisite not departing from the utility model know-why; can also make some improvement and modification, these improve and modification also should be considered as protection domain of the present utility model.
Except the technical characteristic described in description, be the known technology of those skilled in the art.
Claims (2)
1. a fluid control apparatus for radial chromatography post, is characterized in that:
Comprise control panel, sleeve plate and mozzle;
Regularly spread configuration multiple H type guiding gutter on an end face of described control panel, each H type guiding gutter is longitudinally arranged, and arranges at the quadripolar corners of each H type guiding gutter the other end that through hole is communicated to described control panel;
Form a water conservancy diversion module by every four by adjacent H type guiding gutter, and four H type guiding gutters in each water conservancy diversion module are communicated to respective transverse center position by " work " font groove lain low;
Described control panel end face is established eight water conservancy diversion modules altogether, and every mutually by adjacent four water conservancy diversion module compositions one group, and symmetrical about the longitudinal center's broken line on control panel end face;
Four water conservancy diversion modules often in group are communicated to respective transverse center position by " work " font groove lain low;
Cylinder groove is established in the end face center being provided with H type guiding gutter at control panel, and longitudinally establishes two groups of water conservancy diversion modules described in the connection of yi word pattern groove to two ends centered by described cylinder groove;
At the center of described sleeve plate, central through hole is set;
Described sleeve plate is fitted in described control panel establish on an end face of H type guiding gutter, described central through hole is coaxially corresponding with described cylinder groove, and described mozzle one end is connected in described cylinder groove through described central through hole;
Described sleeve plate and described control panel are longitudinally set to tubular and link are sealed after fitting into one and be connected.
2. the fluid control apparatus of radial chromatography post according to claim 1, is characterized in that: described sleeve plate adopts 316L stainless steel, and described control panel adopts polytetrafluoroethylene (PTFE) material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420796905.XU CN204428893U (en) | 2014-12-15 | 2014-12-15 | The fluid control apparatus of radial chromatography post |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420796905.XU CN204428893U (en) | 2014-12-15 | 2014-12-15 | The fluid control apparatus of radial chromatography post |
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| CN204428893U true CN204428893U (en) | 2015-07-01 |
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| CN201420796905.XU Active CN204428893U (en) | 2014-12-15 | 2014-12-15 | The fluid control apparatus of radial chromatography post |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104399281A (en) * | 2014-12-15 | 2015-03-11 | 聊城万合工业制造有限公司 | Liquid flow controller for radial chromatographic column |
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2014
- 2014-12-15 CN CN201420796905.XU patent/CN204428893U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104399281A (en) * | 2014-12-15 | 2015-03-11 | 聊城万合工业制造有限公司 | Liquid flow controller for radial chromatographic column |
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