CN204428153U - In conjunction with the microwave ablation device of electrical impedance imaging - Google Patents
In conjunction with the microwave ablation device of electrical impedance imaging Download PDFInfo
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- CN204428153U CN204428153U CN201420693839.3U CN201420693839U CN204428153U CN 204428153 U CN204428153 U CN 204428153U CN 201420693839 U CN201420693839 U CN 201420693839U CN 204428153 U CN204428153 U CN 204428153U
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Abstract
In conjunction with the microwave ablation device of electrical impedance imaging, comprising: for carrying out the microwave ablation module of microwave ablation to area for treatment; For the formation of the electrical impedance imaging module of the electrical impedance images of area for treatment; The manipulation main frame be connected with described electrical impedance imaging module electricity with described microwave ablation module.After this utility model utilizes microwave ablation, focus is dewatered, the feature that impedance is risen, measure with Review of Electrical Impedance Tomography, measure size of tumor in real time by Review of Electrical Impedance Tomography, thus microwave ablation scope is judged, microwave ablation process is controlled, and real-time monitoring in art He postoperative can be carried out to patient, without the need to injection of contrast medium, low cost, does not increase the financial burden of patient.
Description
Technical field
This utility model belongs to technical field of medical instruments, is specifically related to a kind of microwave ablation device, particularly relates to the microwave ablation device for tumor micro-wound treatment.
Background technology
Microwave ablation is inserted in tumor tissues by implanted microwave antenna (microwave needle), by microwave radiation, microwave antenna surrounding tissue is heated to 65 DEG C ~ 100 DEG C, tissue is dewatered, and then generation coagulation necrosis, and normal surrounding tissue is unaffected.In the process of tissue dewatering to necrosis, its impedance can be risen, and generally rises to 300 more than Ω from about 50 Ω, and its necrotic zone is a high impedance areas.Microwave ablation device generally includes microwave generator, microwave antenna, microwave control unit, and magnetron generates microwave, and antenna connects microwave generator by low consumption coaxial cable, and is transferred in tissue by magnetron by microwave.Current microwave ablation mainly uses 915MHZ and 2450MHZ two kinds of frequencies.
When carrying out microwave ablation, doctor is under B ultrasonic or CT guide, microwave needle Direct perforantes to tumor locus central area, the microwave magnetic field discharged by microwave needle can make the molecule high speed rotary motion of surrounding, in-house polar molecule high-speed motion thus friction generates heat mutually, rapid temperature increases in tumor, when temperature is raised to about 60 degree under the effect of microwave field, cancer cell proteins qualitative change is solidified, and causes irreversible necrosis.Simultaneously very little on the impact of its hetero-organization, be conducive to the immunity improving patient's body, the diffusion of inhibition tumor cell, reaches the object for the treatment of.
A difficult point of microwave ablation is exactly the scope judging to melt, the existing mode can assessing ablation range is CT enhanced ct scans or uses color ultrasound enhanced ct scans clinically at present, but adopt B ultrasonic enhanced ct scans to need patient's injection of contrast medium, could comparatively Measurement accuracy, CT enhanced ct scans expense costly, and can not be measured in real time.
Utility model content
The purpose of this utility model is to provide a kind of microwave ablation device in conjunction with Review of Electrical Impedance Tomography, after utilizing microwave ablation, focus is dewatered, and the feature that impedance is risen is measured with Review of Electrical Impedance Tomography, realize harmless microwave ablation scope to judge, and can monitor in real time patient.
To achieve these goals, this utility model takes following technical solution:
In conjunction with the microwave ablation device of electrical impedance imaging, comprising: for carrying out the microwave ablation module of microwave ablation to area for treatment; For the formation of the electrical impedance imaging module of the electrical impedance images of area for treatment; The manipulation main frame be connected with described electrical impedance imaging module electricity with described microwave ablation module.
Microwave ablation module of the present utility model comprises microwave needle, the microwave generator be connected with described microwave needle, the microwave control unit that is connected with described microwave generator.
Electrical impedance imaging module of the present utility model comprises electrod-array, the electrode gating unit be connected with described electrod-array, the signal amplification circuit be connected with described electrod-array, the excitation signal generator be connected with described electrode gating unit, the demodulator circuit be connected with described signal amplification circuit, the A/D converting unit be connected with described demodulator circuit, to free the control unit that device and described A/D converting unit be connected with described pumping signal.
Manipulation main frame of the present utility model comprises controller and the display module be connected with described controller respectively and human-computer interaction module, controller receives the data from microwave ablation module and electrical impedance imaging module, and to microwave ablation module and the move instruction of electrical impedance imaging module.
Display module of the present utility model and human-computer interaction module are touching display screen.
Manipulation main frame of the present utility model is connected with described electrical impedance imaging module with described microwave ablation module by serial communication interface.
Electrod-array of the present utility model has 32 and with last electrode.
From above technical scheme, after this utility model utilizes microwave ablation, focus is dewatered, cause pathological tissues to contract in the feature of region impedance rising, measure size of tumor in real time by Review of Electrical Impedance Tomography, thus microwave ablation scope is judged, microwave ablation process is controlled, compared with CT enhanced ct scans, B ultrasonic enhanced ct scans mode, employing Review of Electrical Impedance Tomography can realize the real-time monitoring in art, without the need to injection of contrast medium, low cost, does not increase the financial burden of patient; But also can according to the situation terminating the rear guarded region impedance variation for the treatment of, the treatment situation postoperative to patient carries out continuous care.
Accompanying drawing explanation
Fig. 1 is the structural representation of this utility model embodiment.
Below in conjunction with accompanying drawing, detailed description of the invention of the present utility model is described in more detail.
Detailed description of the invention
Electrical impedance imaging (Electrical Impedance Tomography, be called for short EIT) be the technology that a kind of noninvasive resistivity with object body inside is distributed as the rebuilding body inner tissue image of target, the realization of EIT is generally the electrode by arranging some at body surface, selected electrode applies the electric current of certain pattern, then the voltage of each electrode is measured, again by these known electric currents, voltage data, according to image reconstruction algorithm, construct the impedance image of interior of articles, as the distribution of impedance figure of organism inner tissue, the impedance of organism resistance is with the image of frequency change, organism organ physiological activity (is breathed, heartbeat) time impedance variation image.
When carrying out Microwave Coagulation Therapy, microwave current makes pathological tissues be dewatered in downright bad process, and its impedance can be risen, and rises to 300 more than Ω from about 50 Ω, makes necrotic zone form a high impedance areas.This utility model, by the impedance image of Real-Time Monitoring patient, controls microwave ablation process.
As shown in Figure 1, the microwave ablation device of this utility model embodiment comprises microwave ablation module 1, electrical impedance imaging module 2 and manipulation main frame 3, microwave ablation module 1 is for carrying out microwave ablation to area for treatment, electrical impedance imaging module 2 is for the formation of the electrical impedance images of area for treatment, and microwave ablation module 1 and electrical impedance imaging module 2 are electrically connected with manipulation main frame 3 respectively.Wherein, microwave ablation module 1 comprises microwave needle (microwave antenna) 1-1, microwave generator 1-2 and microwave control unit 1-3.Electrical impedance imaging module 2 comprises electrod-array 2-1, excitation signal generator 2-2, electrode gating unit 2-3, signal amplification circuit 2-4, demodulator circuit 2-5, A/D converting unit 2-6, control unit 2-7.Manipulation main frame 3 comprises controller 3-1, display module 3-2 and human-computer interaction module 3-3.
The microwave control unit 1-3 of microwave ablation module 1 is connected with microwave generator 1-2, and microwave generator 1-2 is connected with microwave needle 1-1 by coaxial cable.Microwave control unit 1-3 controls the power stage of microwave generator 1-2, and the coaxial cable that is conveyed through of microwave power is passed to microwave needle 1-1 by microwave generator 1-2, and microwave needle 1-1 microwave radiation energy carries out ablation to tumor and pathological tissues.Microwave control unit of the present utility model can adopt single-chip microcomputer or MCU, and microwave generator can adopt magnetron or transistor, and above each parts all can adopt the conventional design of prior art, and those skilled in the art are without the need to carrying out the improvement on any software to it.
The electrod-array 2-1 of electrical impedance imaging module 2 has 32 with top electrode (comprising 32), and comprising exciting electrode and measurement electrode, electrod-array 2-1 is connected with signal amplification circuit with electrode gating unit respectively.The exciting electrode of electrod-array is connected with the outfan of exciting current in electrode gating unit, and measurement electrode is connected with the input of signal amplification circuit.Electrod-array 2-1 is connected with excitation signal generator 2-2 by electrode gating unit 2-3, electrode gating unit is switch arrays, electrode gating unit is used for according to exciting electrode corresponding in selected motivation model gate array, current excitation signal is applied to measured target surface, and for according to measurement electrode pair corresponding in selected measurement pattern gate array, extract the voltage signal on measured target surface.The model that electrode gating unit can adopt Maxim to produce is the integrated circuit of MAX306 or MAX336CAI.Excitation signal generator 2-2 is connected with control unit 2-7, excitation signal generator can adopt DDS signal source, excitation signal generator is controlled by control unit 2-7, the weighing apparatus pressure signal that it exports is converted to constant-current source through baric flow change-over circuit, through the exciting electrode of electrode gating one-cell switching, be injected into measured target.
Signal amplification circuit 2-4 is connected with electrod-array 2-1, is sent to demodulator circuit 2-5 after voltage signal measurement electrode recorded amplifies, and demodulator circuit 2-5 demodulates real part and the imaginary part of electrical impedance signal from the voltage signal after amplification.Demodulator circuit 2-5 is connected with A/D converting unit 2-6, analogue signal is converted to digital signal and exports control unit 2-7 to by A/D converting unit 2-6, the data of collection are sent to the controller 3-1 of manipulation main frame 3 by control unit 2-7, carry out process and imaging by controller 3-1 to image data.Signal amplification circuit adopts Programmable Gain Amplifier Circuit, if model is the programmable gain amplifier of MCP6S21, demodulator circuit can adopt digital phase-sensitive demodulation module, A/D converting unit can adopt model to be the modulus conversion chip of AD9238, and control unit can adopt single-chip microcomputer or be made up of FPGA and digital signal processor.
Manipulation main frame 3 is connected by serial communication interface with microwave ablation module 1, electrical impedance imaging module 2, as USB connecting line.Manipulation main frame 3 comprises controller 3-1 and the display module 3-2 that is connected with controller 3-1 and human-computer interaction module 3-3, serial communication interface is electrically connected with controller, in manipulation main frame (controller) and microwave ablation module 1, transmits data/commands between electrical impedance imaging module 2.The electrical impedance images that controller process obtains is shown by display module by manipulation main frame 3, and operational order inputs to controller by human-computer interaction module, and sends microwave ablation module and electrical impedance imaging module to by controller.Manipulation main frame of the present utility model can be common computer PC or operation bench, controller is wherein process chip (CPU or MCU), display module can be display screen, human-computer interaction module adopts keyboard or button etc., during display module employing touching display screen, human-computer interaction module is also integrated in wherein, can show various parameter and electrical impedance images, also can receive the parameter of user input, microwave ablation module and electrical impedance imaging module are controlled.
Work process of the present utility model is as follows:
A., before enforcement microwave ablation, at the electrod-array that the body surface of patient is pasted, enable electrod-array wrap up ablation areas, and the penetrating area of microwave needle is avoided in attachment of electrodes position;
B. input region area S to be ablated, region area to be ablated is the lesion area of corresponding aspect, target setting impedance P;
C. the anti-image-forming module of opening resistor, measures the anti-image of the initial resistance impedance image as a setting of human body, and on the CT faultage image of the lesions position that is added to, shows in the color mode of puppet;
D. microwave needle is thrust in penetrating area, open microwave ablation module, start to melt;
E. in microwave ablation process, electrical impedance imaging module measures the electrical impedance images of new human body in real time, as real-time impedance image, do difference with background impedance image, obtain impedance variation image, analyze high impedance areas (impedance is higher than the region of P) area, namely melted downright bad region area (melting the tomography area of stove), if high impedance areas area is greater than S, and the persistent period exceed the value of regulation, then stop microwave exporting, terminate treatment.
Doctor can according to the ablation parameter such as the time of melting, ablation power and high impedance areas area, and whether comprehensive descision focal ablation scope reaches clinical requirement, stops or continues ablation procedure.Impedance image at the end for the treatment of is called and melts impedance image.After terminating treatment, electrical impedance imaging module continues to guard patient, and the tissue coagulation necrosis caused due to high temperature is an irreversible process, namely melt stove after treatment is finished resistance should not change, if after melting stopping, resistance reduces, then point out local to have edema or internal hemorrhage.
Above embodiment is only in order to illustrate that the technical solution of the utility model is not intended to limit, although be described in detail this utility model with reference to above-described embodiment, those of ordinary skill in the field are to be understood that, still can modify to detailed description of the invention of the present utility model or equivalent replacement, and not departing from any amendment of this utility model spirit and scope or equivalent replacement, it all should be encompassed among right of the present utility model.
Claims (7)
1., in conjunction with the microwave ablation device of electrical impedance imaging, it is characterized in that, comprising:
For carrying out the microwave ablation module of microwave ablation to area for treatment;
For the formation of the electrical impedance imaging module of the electrical impedance images of area for treatment;
The manipulation main frame be connected with described electrical impedance imaging module electricity with described microwave ablation module.
2. as claimed in claim 1 in conjunction with the microwave ablation device of electrical impedance imaging, it is characterized in that: described microwave ablation module comprises microwave needle, the microwave generator be connected with described microwave needle, the microwave control unit that is connected with described microwave generator.
3. as claimed in claim 1 or 2 in conjunction with the microwave ablation device of electrical impedance imaging, it is characterized in that: described electrical impedance imaging module comprises electrod-array, the electrode gating unit be connected with described electrod-array, the signal amplification circuit be connected with described electrod-array, the excitation signal generator be connected with described electrode gating unit, the demodulator circuit be connected with described signal amplification circuit, the A/D converting unit be connected with described demodulator circuit, to free the control unit that device and described A/D converting unit be connected with described pumping signal.
4. as claimed in claim 1 or 2 in conjunction with the microwave ablation device of electrical impedance imaging, it is characterized in that: described manipulation main frame comprises controller and the display module be connected with described controller respectively and human-computer interaction module, controller receives the data from microwave ablation module and electrical impedance imaging module, and to microwave ablation module and the move instruction of electrical impedance imaging module.
5. as claimed in claim 4 in conjunction with the microwave ablation device of electrical impedance imaging, it is characterized in that: described display module and human-computer interaction module are touching display screen.
6. as claimed in claim 1 in conjunction with the microwave ablation device of electrical impedance imaging, it is characterized in that: described manipulation main frame is connected with described electrical impedance imaging module with described microwave ablation module by serial communication interface.
7. as claimed in claim 1 in conjunction with the microwave ablation device of electrical impedance imaging, it is characterized in that: described electrod-array has 32 and with last electrode.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201420693839.3U CN204428153U (en) | 2014-11-17 | 2014-11-17 | In conjunction with the microwave ablation device of electrical impedance imaging |
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| CN201420693839.3U CN204428153U (en) | 2014-11-17 | 2014-11-17 | In conjunction with the microwave ablation device of electrical impedance imaging |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112263323A (en) * | 2020-09-30 | 2021-01-26 | 杭州睿笛生物科技有限公司 | Impedance measuring device, ablation equipment and method for generating impedance map |
| CN112603536A (en) * | 2020-12-29 | 2021-04-06 | 北京华科恒生医疗科技有限公司 | Method and system for generating electrode thermal coagulation parameters in three-dimensional model |
| WO2022048138A1 (en) * | 2020-09-03 | 2022-03-10 | 杭州诺诚医疗器械有限公司 | Living body impedance detection device and radio frequency ablation system |
-
2014
- 2014-11-17 CN CN201420693839.3U patent/CN204428153U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022048138A1 (en) * | 2020-09-03 | 2022-03-10 | 杭州诺诚医疗器械有限公司 | Living body impedance detection device and radio frequency ablation system |
| CN112263323A (en) * | 2020-09-30 | 2021-01-26 | 杭州睿笛生物科技有限公司 | Impedance measuring device, ablation equipment and method for generating impedance map |
| CN112263323B (en) * | 2020-09-30 | 2021-10-08 | 杭州睿笛生物科技有限公司 | Impedance measuring device and ablation equipment |
| CN112603536A (en) * | 2020-12-29 | 2021-04-06 | 北京华科恒生医疗科技有限公司 | Method and system for generating electrode thermal coagulation parameters in three-dimensional model |
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