CN204325378U - A kind of cell traction culture apparatus - Google Patents

A kind of cell traction culture apparatus Download PDF

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Publication number
CN204325378U
CN204325378U CN201420850076.9U CN201420850076U CN204325378U CN 204325378 U CN204325378 U CN 204325378U CN 201420850076 U CN201420850076 U CN 201420850076U CN 204325378 U CN204325378 U CN 204325378U
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CN
China
Prior art keywords
gag lever
lever post
box
movable plate
cultivation box
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Expired - Fee Related
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CN201420850076.9U
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Chinese (zh)
Inventor
王平
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Weifang Medical University
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Weifang Medical University
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Priority to CN201420850076.9U priority Critical patent/CN204325378U/en
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Publication of CN204325378U publication Critical patent/CN204325378U/en
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Abstract

The utility model belongs to Bioexperiment equipment technical field, particularly relate to a kind of cell traction culture apparatus, comprise cultivation box, cultivate in box and be provided with two movable plates, cultivate box inner bottom part and be provided with elastic silica gel Membrance cuiture face, the two ends in elastic silica gel Membrance cuiture face lay respectively at movable plate and cultivate between box box wall, between movable plate and pressing plate; Cultivation box box wall has been threaded transmission screw, the first gag lever post and the second gag lever post, and transmission screw connects movable plate by union lever, and transmission screw is connected with motor-driven; The two cultivation box box walls vertical with movable plate are equipped with scale.The cell traction culture apparatus that the utility model provides, is driven the position regulating movable plate, and is provided with the first gag lever post and the second gag lever post, accurately can locate the position of movable plate by motor, regulate accurately, economical convenient, can flexible tractive amplitude.

Description

A kind of cell traction culture apparatus
Technical field
The utility model belongs to Bioexperiment equipment technical field, particularly relates to a kind of cell traction culture apparatus.
Background technology
Under the action of mechanical stress, the growth of cell changes, cell fission is bred, this is very common in medical field, the clinical technology that the limbs traction lengthening of orthopedic skin soft-tissue expansion, stretching technique, orthopaedics and the cranium Jaw distraction art of craniomaxillofacial surgery etc. obtain " additionally " tissue by external force stimulus is based on this principle, this type of phenomenon also sees among some pathological changes, as renal glomerulus hypertension makes it hyperplasia etc. to the Pressure stimulation repeatedly of mesangial cell simultaneously.
Modern biotechnology research shows, outside physiological environment can cellular function have an impact, and wherein mechanics factor plays vital effect to the growth of cell, differentiation, development and immune response.Therefore study cell and how to change mechanical stimulation into intracellular electrochemical signals by after tractive, especially Skeletal Muscle Cell and myocardial cell receive publicity increasingly by the reaction after tractive.
Cell is carried out to the principle of tractive, generally use the bio-compatibility such as silica gel good, less, the resilient material that is easy to deformation of self Young's modulus simultaneously, culturing cell thereon, be close to after growth until cell and silica gel material is stretched, thus drive cell traction.
But current cell cultures is all operate in culture dish, there is no the special device that tractive stress is provided for cell cultures, especially economical convenient again can the cell traction culture apparatus of flexible modulation tractive amplitude.
Utility model content
The purpose of this utility model is to provide a kind of cell traction culture apparatus, not only conveniently economical but also can flexible modulation cell traction amplitude.
The utility model realizes like this, a kind of cell traction culture apparatus, comprise cultivation box, two movable plates be oppositely arranged are provided with in described cultivation box, movable plate described in one is connected with one end box wall of described cultivation box, movable plate described in another is slidably mounted on the middle part of described cultivation box and is connected with pressing plate, described cultivation box inner bottom part is being provided with elastic silica gel Membrance cuiture face between movable plate described in two, the one end in described elastic silica gel Membrance cuiture face is at a movable plate and cultivate between box box wall, the other end is between another movable plate and pressing plate, described movable plate is provided with depression, the pressing plate corresponding with described movable plate and cultivate projection box box wall being respectively equipped with and closing with described recesses,
One end box wall that described cultivation box is relative with movable plate runs through and is provided with threaded pipe, threaded pipe internal thread is connected with transmission screw, one end that described transmission screw is positioned at described cultivation box has been rotatably connected union lever, described union lever is connected with movable plate through described pressing plate, be positioned at outside described cultivation box and be provided with motor, described motor and described transmission screw are in transmission connection;
The box wall that described cultivation box is relative with described pressing plate is provided with the first gag lever post and the second gag lever post, described first gag lever post and the second gag lever post screw thread are arranged on box wall, one end that described first gag lever post and the second gag lever post are positioned at outside described cultivation box box is all installed with knob, described first gag lever post is positioned at cultivates one end of box and pressing plate offsets, described second gag lever post is positioned to be cultivated one end of box and slides through described pressing plate and movable plate and be provided with limiting section and movable plate offsets, and the diameter of described limiting section is greater than the diameter of described second gag lever post;
Vertical with described movable plate two cultivate on box box wall and are equipped with scale.
Improve as one, described first gag lever post and the second gag lever post are equipped with three, described first gag lever post and the distribution all triangular in shape of the second gag lever post and the center superposition of the two triangle surrounded, described transmission screw is positioned at described first gag lever post and the second gag lever post surrounds leg-of-mutton center.
As improving further, described first gag lever post and the second gag lever post spaced apart, adjacent described first gag lever post and the second gag lever post and the first gag lever post or the second gag lever post surround leg-of-mutton center the angle that formed of line be 60 degree.
Improve as one, one end that described first gag lever post is positioned at described cultivation box is connected with a limiting plate, and described limiting plate and described movable plate be arranged in parallel.
Owing to adopting technique scheme, the beneficial effects of the utility model are:
Because one end, elastic silica gel Membrance cuiture face is between a movable plate and cultivation box box wall, the other end is between another movable plate and pressing plate, and movable plate is provided with depression, the pressing plate corresponding with movable plate and cultivation box box wall are respectively equipped with the projection of closing with recesses, elastic silica gel Membrance cuiture face is firmly fixed, one end box wall that cultivation box is relative with movable plate runs through and is provided with threaded pipe, threaded pipe internal thread is connected with transmission screw, transmission screw is connected with movable plate by union lever, and transmission screw connects motor, when the mobile movable plate of needs comes tensile elasticity pellosil cultivation face, starter motor, motor rotation drives transmission screw to rotate, transmission screw relative to rotated threaded tubular thus drive movable plate move, when arriving correct position, disable motor, economical convenient again can flexible modulation tractive amplitude, be provided with the first gag lever post and the second gag lever post, movable plate arrives as required position can regulate the position of the first limiting plate or the second limiting plate in advance, offset with the first limiting plate or the second limiting plate after movable plate moves to corresponding position, restrained stretching rate is carried out in accurate control movable plate shift position, effectively prevent stretching transition or stretch not enough, in order to adjust the position of movable plate more exactly, the two cultivation box box walls vertical with movable plate are equipped with scale, by the first gag lever post or the second gag lever post are adjusted to certain scale place, then movable plate position is regulated, regulate accurately.
Because the first gag lever post and the second gag lever post are equipped with three, and be all triangularly arranged and the center superposition of two triangle, transmission screw is positioned at leg-of-mutton center, the position of accurate restriction movable plate, movable plate plate face just do not tilt in can be made to keep simultaneously, ensure stretching accuracy, especially when the first gag lever post and the second gag lever post spaced apart, and adjacent first gag lever post and the second gag lever post and the first gag lever post or the second gag lever post surround leg-of-mutton center the angle that formed of line when being 60 degree, spacing accurate impression is good.
Be connected with a limiting plate because the first gag lever post is positioned at the one end of cultivating box, limiting plate and movable plate be arranged in parallel, the convenient position regulating limiting plate with reference to scale, and then limit the position of movable plate, and operation accurately facilitates.
Accompanying drawing explanation
Fig. 1 is the structural representation of the present embodiment;
Fig. 2 is the present embodiment internal structure schematic diagram;
Fig. 3 is the distribution schematic diagram of the first gag lever post and the second gag lever post in the present embodiment;
Wherein, 1-cultivates box, 2-movable plate, 3-pressing plate, 4-elastic silica gel Membrance cuiture face, and 5-caves in, and 6-is protruding, 7-threaded pipe, 8-transmission screw, 9-union lever, 10-motor, 11-first gag lever post, 12-second gag lever post, 13-limiting section, 14-scale, 15-limiting plate.
Embodiment
In order to make the purpose of this utility model, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the utility model is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the utility model, and be not used in restriction the utility model.
As Fig. 1, Fig. 2 and Fig. 3 jointly shown in, a kind of cell traction culture apparatus, comprise and cultivate box 1, cultivate in box 1 and be provided with two movable plates be oppositely arranged 2, one movable plate 2 is connected with one end box wall cultivating box 1, another movable plate 2 is slidably mounted on the middle part of cultivation box 1 and is connected with pressing plate 3, cultivate box 1 inner bottom part and be provided with elastic silica gel Membrance cuiture face 4 between two movable plates 2, the one end in elastic silica gel Membrance cuiture face 4 is at a movable plate 2 and cultivate between box 1 box wall, the other end is between another movable plate 2 and pressing plate 3, movable plate 2 is provided with depression 5, the pressing plate 3 corresponding with movable plate 2 is respectively equipped with and 5 projections matched 6 that cave in cultivating on box 1 box wall, particularly, depression 5 can be set to groove or shrinkage pool, movable plate 2 and can being bolted between pressing plate 3 and box wall, easy to connect and detachable,
One end box wall that cultivation box 1 is relative with movable plate 2 runs through and is provided with threaded pipe 7, threaded pipe 7 internal thread is connected with transmission screw 8, transmission screw 8 is positioned to be cultivated one end of box 1 and to be rotatably connected union lever 9, union lever 9 is connected with movable plate 2 through pressing plate 3, be positioned to cultivate outside box 1 and be provided with motor 10, motor 10 and transmission screw 8 are in transmission connection, particularly, output terminal and the circumferential transmission of transmission screw 8 of motor 10 are in axial sliding connection, drive transmission screw 8 to rotate when motor 10 operates, transmission screw 8 can axially move freely again simultaneously, in actual use, in order to transmission screw 8 is axially steadily mobile, the screw thread arranged on transmission screw 8 and threaded pipe 7 is two start screw or multi-step thread,
The box wall cultivating box 1 relative with pressing plate 3 is provided with the first gag lever post 11 and the second gag lever post 12, first gag lever post 11 and the second gag lever post 12 screw thread are arranged on box wall, first gag lever post 11 and the second gag lever post 12 are positioned at the one end of cultivating outside box 1 box and are all installed with knob, first gag lever post 11 is positioned at cultivates one end of box 1 and pressing plate 3 offsets, second gag lever post 12 is positioned to be cultivated one end of box 1 and slides through pressing plate 3 and movable plate 2 and be provided with limiting section 13 and offset with movable plate 2, and the diameter of limiting section 13 is greater than the diameter of the second gag lever post 12;
Vertical with movable plate 2 two cultivate on box 1 box wall and are equipped with scale 14.
In the present embodiment, first gag lever post 11 and the second gag lever post 12 are equipped with three, first gag lever post 11 and the distribution all triangular in shape of the second gag lever post 12 and the center superposition of the two triangle surrounded, transmission screw 8 be positioned at the first gag lever post 11 and the second gag lever post 12 surround leg-of-mutton center.
Preferably, the first gag lever post 11 and the second gag lever post 12 spaced apart, adjacent first gag lever post 11 and the second gag lever post 12 and the first gag lever post 11 or the second gag lever post 12 surround leg-of-mutton center the angle α that formed of line be 60 degree.
In the present embodiment, the first gag lever post 11 is positioned at the one end of cultivating box 1 and is connected with a limiting plate 15, and limiting plate 15 and movable plate 2 be arranged in parallel.
The cell traction culture apparatus that the utility model provides, is driven the position regulating movable plate 2, and is provided with the first gag lever post 11 and the second gag lever post 12 by motor 10, accurately can locate the position of movable plate 2, regulate accurately, economical convenient, can flexible tractive amplitude.
The foregoing is only preferred embodiment of the present utility model; not in order to limit the utility model; all do within spirit of the present utility model and principle any amendment, equivalent to replace and improvement etc., all should be included within protection domain of the present utility model.

Claims (4)

1. a cell traction culture apparatus, comprise cultivation box, it is characterized in that, two movable plates be oppositely arranged are provided with in described cultivation box, movable plate described in one is connected with one end box wall of described cultivation box, movable plate described in another is slidably mounted on the middle part of described cultivation box and is connected with pressing plate, described cultivation box inner bottom part is being provided with elastic silica gel Membrance cuiture face between movable plate described in two, the one end in described elastic silica gel Membrance cuiture face is at a movable plate and cultivate between box box wall, the other end is between another movable plate and pressing plate, described movable plate is provided with depression, the pressing plate corresponding with described movable plate and cultivate projection box box wall being respectively equipped with and closing with described recesses,
One end box wall that described cultivation box is relative with movable plate runs through and is provided with threaded pipe, threaded pipe internal thread is connected with transmission screw, one end that described transmission screw is positioned at described cultivation box has been rotatably connected union lever, described union lever is connected with movable plate through described pressing plate, be positioned at outside described cultivation box and be provided with motor, described motor and described transmission screw are in transmission connection;
The box wall that described cultivation box is relative with described pressing plate is provided with the first gag lever post and the second gag lever post, described first gag lever post and the second gag lever post screw thread are arranged on box wall, one end that described first gag lever post and the second gag lever post are positioned at outside described cultivation box box is all installed with knob, described first gag lever post is positioned at cultivates one end of box and pressing plate offsets, described second gag lever post is positioned to be cultivated one end of box and slides through described pressing plate and movable plate and be provided with limiting section and movable plate offsets, and the diameter of described limiting section is greater than the diameter of described second gag lever post;
Vertical with described movable plate two cultivate on box box wall and are equipped with scale.
2. cell traction culture apparatus according to claim 1, it is characterized in that, described first gag lever post and the second gag lever post are equipped with three, described first gag lever post and the distribution all triangular in shape of the second gag lever post and the center superposition of the two triangle surrounded, described transmission screw is positioned at described first gag lever post and the second gag lever post surrounds leg-of-mutton center.
3. cell traction culture apparatus according to claim 2, it is characterized in that, described first gag lever post and the second gag lever post spaced apart, adjacent described first gag lever post and the second gag lever post and the first gag lever post or the second gag lever post surround leg-of-mutton center the angle that formed of line be 60 degree.
4. the cell traction culture apparatus according to Claims 2 or 3, is characterized in that, one end that described first gag lever post is positioned at described cultivation box is connected with a limiting plate, and described limiting plate and described movable plate be arranged in parallel.
CN201420850076.9U 2014-12-26 2014-12-26 A kind of cell traction culture apparatus Expired - Fee Related CN204325378U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420850076.9U CN204325378U (en) 2014-12-26 2014-12-26 A kind of cell traction culture apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201420850076.9U CN204325378U (en) 2014-12-26 2014-12-26 A kind of cell traction culture apparatus

Publications (1)

Publication Number Publication Date
CN204325378U true CN204325378U (en) 2015-05-13

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108795760A (en) * 2018-07-05 2018-11-13 广州市天河诺亚生物工程有限公司 Dynamic 3D culture apparatus and dynamic 3D cultural methods

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108795760A (en) * 2018-07-05 2018-11-13 广州市天河诺亚生物工程有限公司 Dynamic 3D culture apparatus and dynamic 3D cultural methods
CN108795760B (en) * 2018-07-05 2021-08-17 广州市天河诺亚生物工程有限公司 Dynamic 3D culture device and dynamic 3D culture method

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20150513

Termination date: 20161226