CN204261383U - A kind of automatic segmentation collects chromatographic column - Google Patents

A kind of automatic segmentation collects chromatographic column Download PDF

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Publication number
CN204261383U
CN204261383U CN201420680423.8U CN201420680423U CN204261383U CN 204261383 U CN204261383 U CN 204261383U CN 201420680423 U CN201420680423 U CN 201420680423U CN 204261383 U CN204261383 U CN 204261383U
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China
Prior art keywords
fluid reservoir
low level
chromatographic column
automatic segmentation
vanning
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Active
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CN201420680423.8U
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Chinese (zh)
Inventor
张必荣
李秀妮
张敏
张勇
闫高颖
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Shaanxi Tiangu Pharmaceutical Co.,Ltd.
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SHAANXI TEEGOO BIOTECHNOLOGY GROUP Co Ltd
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Abstract

The utility model discloses a kind of automatic segmentation and collect chromatographic column, comprise: high-order fluid reservoir (1), chromatography tank body and low level fluid reservoir (12), the top of low level fluid reservoir is provided with Fractional Collections vanning (10), the bottom of Fractional Collections vanning (10) is provided with multiple circular hole, and these circular holes connect different low level fluid reservoirs (12) respectively, wherein, each circular hole is provided with the ball float (11) of different densities, and described Fractional Collections vanning (10), low level fluid reservoir (12) and ball float (11) form an automatic segmentation gathering-device.After the utility model takes such scheme, eluent component difference in specific gravity is utilized to be collected into different storage tank to the buoyancy difference of different densities ball float respectively to eluent easily.Equipment operating is simple, and equipment cost is little, and very limits also reduces manual operation, and a people can be operated numerous chromatographic column simultaneously simultaneously.

Description

A kind of automatic segmentation collects chromatographic column
Technical field
The novel separation and purification mechanical device relating to a kind of biological products of this application, specifically refers to that automatic segmentation collects chromatographic column.
Background technology
At present, known biological products chromatography column apparatus, collection process carries out tapping Fractional Collections after generally adopting and manually surveying proportion (alcoholic degree) again.
Utility model content
Adopt artificial batch (-type) to measure alcoholic degree to overcome existing Column eluate collection link, have a strong impact on production efficiency, easily draw many deficiencies such as eluent component intersection simultaneously, the utility model provides a kind of automatic segmentation to collect chromatographic column.
It is as follows that the utility model solves the problems of the technologies described above taked technical scheme:
A kind of automatic segmentation collects chromatographic column, comprise: high-order fluid reservoir (1), chromatography tank body and low level fluid reservoir (12), the top of low level fluid reservoir is provided with Fractional Collections vanning (10), the bottom of Fractional Collections vanning (10) is provided with multiple circular hole, and these circular holes connect different low level fluid reservoirs (12) respectively, wherein, each circular hole is provided with the ball float (11) of different densities, and described Fractional Collections vanning (10), low level fluid reservoir (12) and ball float (11) form an automatic segmentation gathering-device.
Further, preferably, described chromatography tank interior is provided with from top to down successively: column cap (4), dehydration cap (5), chromatographic column (6) and resin bed (8), and is provided with form (7) in the outside of chromatography tank body.
Further, preferably, pipeline valve (2) and feed tube (3) is provided with between high-order fluid reservoir (1) and chromatography tank body.
Further, preferably, tapping valve (9) is provided with between chromatography tank body and low level fluid reservoir (12).
After the utility model takes such scheme, eluent component difference in specific gravity is utilized to be collected into different storage tank to the buoyancy difference of different densities ball float respectively to eluent easily.Equipment operating is simple, and equipment cost is little, and very limits also reduces manual operation, and a people can be operated numerous chromatographic column simultaneously simultaneously.
Other features and advantages of the utility model will be set forth in the following description, and, partly become apparent from description, or understand by implementing the utility model.The purpose of this utility model and other advantages realize by structure specifically noted in write description, claims and accompanying drawing and obtain.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the utility model is described in detail, to make above-mentioned advantage of the present utility model definitely.
Fig. 1 is the structural representation that the utility model automatic segmentation collects chromatographic column.
Detailed description of the invention
Below in conjunction with specific embodiment, the utility model is described in detail.
Specifically, a kind of automatic segmentation collects chromatographic column, is made up of high-order fluid reservoir, pipeline valve, feed tube, column cap, dehydration cap, chromatographic column, form, resin, tapping valve, Fractional Collections vanning, ball float, low level fluid reservoir.Described automatic segmentation is collected chromatographic column bleeder valve and is carried out the floating ball device of Fractional Collections from being provided with different according to proportion between low level storage tank.It is applicable to the separation and purification of the column chromatography of biological products.
Wherein, the utility model solves the technical scheme that its technical problem adopts and is: the automatic segmentation be made up of high-order fluid reservoir, pipeline valve, feed tube, column cap, dehydration cap, chromatographic column, form, resin, tapping valve, Fractional Collections vanning, ball float, low level fluid reservoir collects chromatographic column.The Fractional Collections floating ball device that described automatic segmentation collection chromatographic column bleeder valve is different from being provided with foundation proportion between low level storage tank and design, wherein ball float averag density can be arranged according to eluent density, when eluent density is less than ball float density, eluent overflows from liquid spill-way and enters next ball float groove, to reach the object of automatically collecting.
The novel benefit effect of this application is that reasonable in design, compact conformation, automaticity is high, and cost is low, significantly reduces labo r usage, improves separative efficiency simultaneously.
As shown in Figure 1, a kind of automatic segmentation collects chromatographic column, comprise: high-order fluid reservoir 1, chromatography tank body and low level fluid reservoir 12, the top of low level fluid reservoir is provided with Fractional Collections vanning 10, described low level fluid reservoir 12 arranges multiple, the bottom of Fractional Collections vanning 10 is provided with multiple circular hole, and these circular holes connect different low level fluid reservoirs 12 respectively, wherein, each circular hole is provided with the ball float 11 of different densities, and described Fractional Collections vanning 10, low level fluid reservoir 12 and ball float 11 form an automatic segmentation and collect chromatographic column mechanism.
Further, preferably, described chromatography tank interior is provided with from top to down successively: column cap 4, dehydration cap 5, chromatographic column 6 and resin bed 8, and is provided with form 7 in the outside of chromatography tank body.
Further, preferably, pipeline valve 2 and feed tube 3 is provided with between high-order fluid reservoir 1 and chromatography tank body.
Further, preferably, tapping valve 9 is provided with between chromatography tank body and low level fluid reservoir 12.
After the utility model takes such scheme, eluent component difference in specific gravity is utilized to be collected into different storage tank to the buoyancy difference of different densities ball float respectively to eluent easily.Equipment operating is simple, and equipment cost is little, and very limits also reduces manual operation, and a people can be operated numerous chromatographic column simultaneously simultaneously.
Last it is noted that the foregoing is only preferred embodiment of the present utility model, be not limited to the utility model, although be described in detail the utility model with reference to previous embodiment, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.All within spirit of the present utility model and principle, any amendment done, equivalent replacement, improvement etc., all should be included within protection domain of the present utility model.

Claims (4)

1. an automatic segmentation collects chromatographic column, comprise: high-order fluid reservoir (1), chromatography tank body and low level fluid reservoir (12), the top of low level fluid reservoir is provided with Fractional Collections vanning (10), it is characterized in that, the bottom of described Fractional Collections vanning (10) is provided with multiple circular hole, and these circular holes connect different low level fluid reservoirs (12) respectively, wherein, each circular hole is provided with the ball float (11) of different densities, and described Fractional Collections vanning (10), low level fluid reservoir (12) and ball float (11) form an automatic segmentation gathering-device.
2. automatic segmentation according to claim 1 collects chromatographic column, it is characterized in that, described chromatography tank interior is provided with from top to down successively: column cap (4), dehydration cap (5), chromatographic column (6) and resin bed (8), and is provided with form (7) in the outside of chromatography tank body.
3. automatic segmentation according to claim 1 and 2 collects chromatographic column, it is characterized in that, is provided with pipeline valve (2) and feed tube (3) between high-order fluid reservoir (1) and chromatography tank body.
4. automatic segmentation according to claim 1 and 2 collects chromatographic column, it is characterized in that, is provided with tapping valve (9) between chromatography tank body and low level fluid reservoir (12).
CN201420680423.8U 2014-11-14 2014-11-14 A kind of automatic segmentation collects chromatographic column Active CN204261383U (en)

Priority Applications (1)

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CN201420680423.8U CN204261383U (en) 2014-11-14 2014-11-14 A kind of automatic segmentation collects chromatographic column

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Application Number Priority Date Filing Date Title
CN201420680423.8U CN204261383U (en) 2014-11-14 2014-11-14 A kind of automatic segmentation collects chromatographic column

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CN204261383U true CN204261383U (en) 2015-04-15

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105597369A (en) * 2016-03-01 2016-05-25 永州星辰生物科技有限公司 Chromatography tank for artemisinin extraction and efficient pressurized chromatography method thereof
CN108854158A (en) * 2017-05-16 2018-11-23 湖北生物医药产业技术研究院有限公司 Resin column elutes liquor collecting device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105597369A (en) * 2016-03-01 2016-05-25 永州星辰生物科技有限公司 Chromatography tank for artemisinin extraction and efficient pressurized chromatography method thereof
CN108854158A (en) * 2017-05-16 2018-11-23 湖北生物医药产业技术研究院有限公司 Resin column elutes liquor collecting device
CN108854158B (en) * 2017-05-16 2023-11-07 湖北生物医药产业技术研究院有限公司 Resin column eluent collection device

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C14 Grant of patent or utility model
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TR01 Transfer of patent right

Effective date of registration: 20211214

Address after: 723200 Liulin Town, Chenggu County, Hanzhong City, Shaanxi Province

Patentee after: Shaanxi Tiangu Pharmaceutical Co.,Ltd.

Address before: Room 10608, unit 1, building 6, Tsinghua Science Park, No. 65, Keji Second Road, high tech Zone, Xi'an, Shaanxi 710065

Patentee before: SHAANXI TEEGOO BIOTECHNOLOGY GROUP Co.,Ltd.

TR01 Transfer of patent right