CN204237803U - A kind of adjust ph borate buffer substrate tablet - Google Patents

A kind of adjust ph borate buffer substrate tablet Download PDF

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Publication number
CN204237803U
CN204237803U CN201420118992.3U CN201420118992U CN204237803U CN 204237803 U CN204237803 U CN 204237803U CN 201420118992 U CN201420118992 U CN 201420118992U CN 204237803 U CN204237803 U CN 204237803U
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CN
China
Prior art keywords
tablet
cross
boric acid
borate
adjust
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201420118992.3U
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Chinese (zh)
Inventor
梁玉明
贾伟青
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TIANJIN BAILUNSI BIOLOGICAL TECHNOLOGY Co Ltd
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TIANJIN BAILUNSI BIOLOGICAL TECHNOLOGY Co Ltd
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Filing date
Publication date
Application filed by TIANJIN BAILUNSI BIOLOGICAL TECHNOLOGY Co Ltd filed Critical TIANJIN BAILUNSI BIOLOGICAL TECHNOLOGY Co Ltd
Priority to CN201420118992.3U priority Critical patent/CN204237803U/en
Application granted granted Critical
Publication of CN204237803U publication Critical patent/CN204237803U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model relates to a kind of adjust ph borate buffer substrate tablet, described tablet is that cross section is rounded, square, rhombus, cruciate flower shape thin slice, consisting of of tablet: described major ingredient is boric acid; Described auxiliary material is borax; Described disintegrating agent is cross-linked amylose, Microcrystalline Cellulose or polyvinylpolypyrrolidone etc., and described tackiness agent is cross-linked amylose, Microcrystalline Cellulose, polyvinylpyrrolidone, partly-hydrolysed polyvinyl alcohol, amylopectin.The application prepares a kind of pH damping fluid first and regulates borate buffering tablet, by precise boric acid, borate and auxiliary agent, after mixing, compressing tablet is made by a certain percentage, material composition is fixed, and the crystal water of boric acid is immutable, secures the ratio between the content of often kind of composition and composition, ensure that the stability of pH value during each use, the phenomenon that the PH that the environmental factors of effective eliminating causes is inaccurate, ensures carrying out smoothly of experiment, and the accuracy of result.

Description

A kind of adjust ph borate buffer substrate tablet
Technical field
The utility model belongs to chemicals technical field, relates to the auxiliary reagent in biology, medical science and chemical test, specifically provides a kind of adjust ph borate buffer substrate tablet.
Background technology
Buffered soln is a kind of solution can resisted pH when adding a small amount of acid or alkali and change.PH buffered soln to maintaining biological normal ph, normal physiological context plays an important role.Most cell only can carry out activity within the scope of very narrow pH, and needs buffer system to resist the pH change occurred in metabolic process.
Buffered soln is auxiliary reagent conventional in biology, medical science and chemical experiment, and frequency of utilization is high, usually uses and once just needs oneself preparation once, and therefore prepare buffer salt solution and seem very numerous and diverse time-consuming, workload is large
Borate buffer solution (BBS) is one of biomedical the most frequently used buffer system, by chemical reagent such as precise boric acid, borates, be mixed by a certain percentage, and it is high to reagent requirement content, crystal water is accurate, structure does not change, especially at borax under different humidity, under degree different condition that there was dampness in the air, its crystal water is unfixed, so the buffered soln prepared with general reagent level borax, pH has very big error, so a kind of method finding simple and quick preparation buffered soln is very important.
Utility model content
The purpose of this utility model is to overcome the deficiencies in the prior art part, a kind of adjust ph borate buffer substrate tablet is provided, adopt pressed disc technique, prepare auxiliary reagent experiment reaction environment soda acid situation being played to shock absorption, the plurality of advantages such as tablet has plug and play, is easy to storage and custody, preparation method is simple and quick.
The technical scheme that the utility model realizes object is as follows:
A kind of adjust ph borate buffer substrate tablet, described tablet is that cross section is rounded, square, rhombus, cruciate flower shape thin slice.
And the thickness of described thin slice is 1-10mm.
And the moiety of described thin slice is: major ingredient, auxiliary material, disintegrating agent, tackiness agent.
And described major ingredient is boric acid; Described auxiliary material is borax; Described disintegrating agent is cross-linked amylose, Microcrystalline Cellulose or polyvinylpolypyrrolidone etc., and described tackiness agent is cross-linked amylose, Microcrystalline Cellulose, polyvinylpyrrolidone, partly-hydrolysed polyvinyl alcohol, amylopectin.
And, there is bubble in described thin slice.
The beneficial effects of the utility model are as follows:
1, the application prepares a kind of pH damping fluid first and regulates borate buffering tablet, by precise boric acid, borate and auxiliary agent, after mixing, compressing tablet is made by a certain percentage, material composition is fixed, and the crystal water of boric acid is immutable, secures the ratio between the content of often kind of composition and composition, ensure that the stability of the value of pH during each use, the phenomenon that the pH that the environmental factors of effective eliminating causes is inaccurate, ensures carrying out smoothly of experiment, and the accuracy of result.
2, the borate buffering tablet that prepared by the application belongs to model of instant use once to turn it on, as long as in the solvent of fixed volume, drops into tablet, just can dissolve rapidly, the buffered soln of the pH value accurate stable needed for can obtaining, use and easy, reduce the duplication of labour, reduce labour intensity, increase work efficiency.
3, the borate buffering tablet that the application provides is easy to storage and custody, and be easy to carry transport, is convenient to pack, extends the storage life, reduces and produce and use cost.
4, the preparation that the borate that the application provides cushions tablet is simple and quick, and preparation process does not relate to high-temperature high-voltage reaction, can carry out suitability for industrialized production.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model:
Fig. 2 is the sectional view of the alveolate thin slice of inner band;
Fig. 3 is structural representation of the present utility model;
Fig. 4 is the utility model preparation of sections artwork;
Fig. 5 is for being structural representation of the present utility model.
Embodiment
Below in conjunction with accompanying drawing, also by specific embodiment, the utility model is described in further detail, and following examples are descriptive, are not determinate, can not limit protection domain of the present utility model with this.
A kind of adjust ph borate cushions tablet, cross section is the thin slice of circular 1 or square 3, can also be made other as ellipse, the thin slice such as rectangle, rhombus, in order to increase dissolution rate, in circle or square sheet, fill small bubbles 2, it is cruciate flower shape or dentation that tablet can also be prepared into cross section, which increase surface-area, add dissolution rate.The thickness of thin slice is that 1-10mm is the most suitable, dissolves very fast like this.
Preparation of sections method steps is as follows:
1, purifying dry major ingredient, auxiliary material, get 100-200 order particle;
2, precise main materials and auxiliary materials, tackiness agent, disintegrating agent, major ingredient-boric acid, auxiliary material-borax, disintegrating agent-cross-linked amylose, Microcrystalline Cellulose, polyvinylpolypyrrolidone etc., tackiness agent-cross-linked amylose, Microcrystalline Cellulose, polyvinylpyrrolidone, partly-hydrolysed polyvinyl alcohol, amylopectin etc.
3, coupling mixing, stirs;
4, adjustment tabletting machine pressure, compressing tablet, pressure 2-4 ton;
5, weigh, test passes;
6, pack.
Several concrete method for preparing slices is below provided.
Embodiment 1
A kind of pH8.2 borate (BBS) cushions tablet, and preparation method is as follows:
(1), by weight being 4:3.3:1.8:0.2, take boric acid, borax, Repone K, each some weight of cross-linked amylose successively respectively, such as: take boric acid 40g, borax 33g, Repone K 18g, cross-linked amylose 2g, coupling mixing and stirring;
(2) on tabletting machine, be pressed into tablet, pressing pressure is 3 tons, suppresses 30, and the heavy 3.1g of every sheet, boronic acid containing, borax, Repone K, cross-linked amylose, its part by weight is followed successively by 4:3.3:1.8:0.2.
During use, a slice preparation 500ml solution, its pH=8.2.
Embodiment 2
A kind of pH7.4 borate (BBS) cushions tablet, and preparation process is as follows:
(1), by weight being 5.6:0.95:1.8:0.25, take boric acid, borax, Repone K, each some weight of cross-linked amylose successively respectively, such as: take boric acid 56g, borax 9.5g, Repone K 18g, cross-linked amylose 2.5g, coupling mixing and stirring;
(2) on tabletting machine, be pressed into tablet, pressing pressure is 4 tons, and suppress 40, every sheet 2.15g, boronic acid containing, borax, Repone K, cross-linked amylose, its part by weight is followed successively by 5.6:0.95:1.8:0.25.
During use, a slice preparation 500ml solution, its pH=7.4.
Embodiment 3
A kind of pH9.0 borate (BBS) cushions tablet, and preparation method is as follows:
(1), by weight being 1.25:7.65:1.0:0.3, take boric acid, borax, Repone K, each some weight of cross-linked amylose successively respectively, such as: take boric acid 12.5g, borax 76.5g, Repone K 10g, cross-linked amylose 3g, coupling mixing and stirring;
(2) on tabletting machine, be pressed into tablet, pressing pressure is 3 tons, and suppress 40, every sheet 2.55g, boronic acid containing, borax, Repone K, cross-linked amylose, its part by weight is followed successively by 1.25:7.65:1.0:0.3.
During use, a slice preparation 500ml solution, its pH=9.0.

Claims (1)

1. an adjust ph borate buffer substrate tablet, is characterized in that: described tablet is that cross section is rounded, square, rhombus, cruciate flower shape thin slice, the thickness of described thin slice is 1-10mm, has bubble in described thin slice.
CN201420118992.3U 2014-03-17 2014-03-17 A kind of adjust ph borate buffer substrate tablet Expired - Fee Related CN204237803U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420118992.3U CN204237803U (en) 2014-03-17 2014-03-17 A kind of adjust ph borate buffer substrate tablet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201420118992.3U CN204237803U (en) 2014-03-17 2014-03-17 A kind of adjust ph borate buffer substrate tablet

Publications (1)

Publication Number Publication Date
CN204237803U true CN204237803U (en) 2015-04-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201420118992.3U Expired - Fee Related CN204237803U (en) 2014-03-17 2014-03-17 A kind of adjust ph borate buffer substrate tablet

Country Status (1)

Country Link
CN (1) CN204237803U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108456050A (en) * 2018-01-24 2018-08-28 天津水泥工业设计研究院有限公司 A kind of pelletizing additives of the production rounded grain mineral fertilizer of low cost

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108456050A (en) * 2018-01-24 2018-08-28 天津水泥工业设计研究院有限公司 A kind of pelletizing additives of the production rounded grain mineral fertilizer of low cost

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150401

Termination date: 20160317

CF01 Termination of patent right due to non-payment of annual fee