CN204134550U - A kind of device for the mixing of magnetic particle - Google Patents
A kind of device for the mixing of magnetic particle Download PDFInfo
- Publication number
- CN204134550U CN204134550U CN201420557217.8U CN201420557217U CN204134550U CN 204134550 U CN204134550 U CN 204134550U CN 201420557217 U CN201420557217 U CN 201420557217U CN 204134550 U CN204134550 U CN 204134550U
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- CN
- China
- Prior art keywords
- mixing
- rotating shaft
- pressuring plate
- motor
- elastic pressuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/201—Holders therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/22—Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/275—Mixing the contents of independent containers, e.g. test tubes with means for transporting test tubes to and from the stirring device
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
- B01F35/42—Clamping or holding arrangements for mounting receptacles on mixing devices
- B01F35/422—Clamping or holding arrangements for mounting receptacles on mixing devices having a jaw-type or finger-type shape
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00534—Mixing by a special element, e.g. stirrer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00564—Handling or washing solid phase elements, e.g. beads
Abstract
The utility model discloses a kind of for magnetic particle mixing device, comprise brshless DC motor, motor cabinet, band bearing eccentric shaft, mixing rotating shaft and mixing head; Described brshless DC motor is arranged on described motor cabinet, the rotating shaft of brshless DC motor is connected through the eccentric shaft of motor cabinet with band bearing, the eccentric shaft of described band bearing, mixing rotating shaft and mixing head are connected successively, and mixing head rest is lived reaction cup and rotated, and realizes mixing.By arranging elastic pressuring plate mechanism, can effectively prevent reaction cup from ejecting from putting hole in blending process; Total is simple, easy for installation, can carry out simply with the magnetic separation system of chemiluminescence immune assay equipment and be combined closely, complete mixing function, without the need to peripheral hardware blending system separately again.
Description
Technical field
The utility model relates to a kind of device for the mixing of magnetic particle.
Background technology
Along with the development of magnetic particle technology, chemiluminescence immunoassay technology obtains applying more and more widely in medical industry.Automatic chemiluminescence immunoassay equipment, in test process, needs to use nanometer magnetic bead and antibody, antigen combine, and nanometer magnetic bead and antibody, antigen need the remaining liquid in cleaning reaction cup after combining, this will have Magneto separate mechanism; But a lot of projects of present chemiluminescence immune assay need to carry out secondary to the material in reaction cup hatches, and this just needs evenly mixing device and carries out mixing action to the magnetic particle in reaction cup and reagent etc.At present, in Full-automatic chemiluminescence apparatus device, most of Magneto separate mechanisms peripheral hardware evenly mixing device, makes chemiluminescence immune assay flow process lengthen; And can not space be made full use of.If evenly mixing device can be provided with in Magneto separate mechanism, when carrying out the motion flow of a certain station, mixing motion flow can be carried out simultaneously, the equipment speed of service so just can be made faster, make analysis process more terse, improve analysis efficiency.
Utility model content
Technical problem to be solved in the utility model is that Magneto separate mechanism completes mixing by peripheral hardware evenly mixing device, adds equipment cost, and motion flow is long affects the problems such as efficiency.
For a device for magnetic particle mixing, comprise brshless DC motor 1, motor cabinet 2, the eccentric shaft 3 of band bearing, mixing rotating shaft 5 and mixing 7;
Described brshless DC motor 1 is arranged on described motor cabinet 2, the rotating shaft of brshless DC motor 1 is connected through the eccentric shaft 3 of motor cabinet 2 with band bearing, the eccentric shaft 3 of described band bearing, mixing rotating shaft 5 and mixing 7 is connected successively, and mixing head rest is lived reaction cup 30 and rotated, and realizes mixing.
[evenly mixing device of the present utility model is integrated in Magneto separate mechanism, when reaction cup moves to mixing position, the mixing head be positioned at below reaction cup carries out eccentric rotary, thus makes reaction cup carry out eccentric rotary thus make the material in reaction cup carry out mixing mixing; ]
Also comprise climbing lifting mechanism, described climbing lifting mechanism comprises low order climbing block 8 and high-order climbing block 9;
Be arranged on the mixing 7 of mixing station between described low order climbing block and described high-order climbing block;
The peak of described low order climbing block and the minimum point of high-order climbing block all with mix parallel;
Reaction cup with in dial movement process along low order climbing block climb rise to mixing station mixing head on, climb to rise to get a glass station along high-order climbing block.
[rotary motion of climbing block and rotating disk forms climbing lifting action, without the need to other lifting mechanism lifting reaction cup.】
The surface of described climbing lifting mechanism and the bottom arc surface of reaction cup tangent.
[along with the rotational response cup arc surface of rotating disk is along climbing block surface sliding, along with the face with climbing block raises, progressively lifting.】
Described mixing machine device is provided with mixing seat 6, and mixing seat is fixed on motor cabinet 2; Described mixing rotating shaft, through mixing seat, between mixing seat and mixing rotating shaft, mixing rotating shaft is set with Compress Spring 4.
Described evenly mixing device is also provided with elastic pressuring plate external member 10, and described elastic pressuring plate external member 10 comprises elastic pressuring plate mount pad 11, extension spring 12, blind rivet 13, compressing tablet 14, second bearing pin 15 and adjustment screw 16;
Described elastic pressuring plate mount pad 11 is fixed on the installing plate 21 of Magneto separate mechanism 20, described compressing tablet 14 is connected with elastic pressuring plate mount pad 11 by bearing pin 15, described adjustment screw 16 screws in elastic pressuring plate mount pad 11 by described compressing tablet 14 jack-up, extension spring 12 one end is hooked on compressing tablet 14, and the other end hooks the blind rivet 13 be fixed on elastic pressuring plate mount pad 11;
Described compressing tablet offers adjustment hole 17, change the height of adjustment screw through adjustment hole 17; The diameter of described adjustment hole 17 is larger than the internal diameter of adjustment screw 16, and less than the external diameter of adjustment screw;
Described adjustment screw is holding screw.
[inner hexagon spanner is utilized to pass adjustment hole 17 turn adjustment screw, change the screw-in depth of adjustment screw in elastic pressuring plate mount pad, thus change the angle of compressing tablet and horizontal plane, namely the pivot angle of compressing tablet 17 is regulated, reaction cup is made to arrive mixing position smoothly along compressing tablet direction, in blending process, compressing tablet blocks reaction cup, prevents reaction cup in blending process from ejecting from putting hole.】
Beneficial effect
A kind of device for the mixing of magnetic particle that the utility model proposes, comprises brshless DC motor 1, motor cabinet 2, the eccentric shaft 3 of band bearing, mixing rotating shaft 5 and mixing 7; Described brshless DC motor 1 is arranged on described motor cabinet 2, the rotating shaft of brshless DC motor 1 is connected through the eccentric shaft 3 of motor cabinet 2 with band bearing, the eccentric shaft 3 of described band bearing, mixing rotating shaft 5 and mixing 7 is connected successively, and mixing head rest is lived reaction cup 30 and rotated, and realizes mixing.
Evenly mixing device of the present utility model is integrated in Magneto separate mechanism, and when reaction cup moves to mixing position, the mixing head be positioned at below reaction cup carries out eccentric rotary, thus makes reaction cup carry out eccentric rotary thus make the material in reaction cup carry out mixing mixing; The lifting climbing block of ingehious design, can reaction cup segmentation lifting, first arrives mixing height, then is lifted to and gets cup height, getting the convenient pickup in cup position, without the need to other lifting mechanism lifting reaction cup.
By the setting of elastic pressuring plate mechanism, in blending process, effectively prevent reaction cup from ejecting from putting hole; Total is simple, easy for installation, can carry out simply with the magnetic separation system of chemical illumination immunity analysis instrument device and be combined closely, complete mixing function, without the need to peripheral hardware blending system separately again.
Accompanying drawing explanation
Fig. 1 is the schematic diagram that evenly mixing device of the present utility model is integrated in Magneto separate mechanism;
Fig. 2 is the evenly mixing device schematic diagram except elastic pressuring plate external member and climbing block of the present utility model, and wherein, (a) is stereogram, and (b) is profile;
Fig. 3 is elastic pressuring plate external member schematic diagram of the present utility model, and wherein, (a) is stereogram, and (b) is profile;
Fig. 4 is climbing block close-up schematic view of the present utility model;
Label declaration:
1-brshless DC motor, 2-motor cabinet, 3-are with the eccentric shaft of bearing, 4-Compress Spring, 5-to mix rotating shaft, 7-mixing head, 6-mixing seat, 8-low order climbing block, 9-high-order climbing block, 10-elastic pressuring plate external member, 11-elastic pressuring plate mount pad, 12-extension spring, 13-blind rivet, 14-compressing tablet, 15-second bearing pin, 16-adjustment screw, 17-adjustment hole, 20-Magneto separate mechanism, 21-installing plate, 30-reaction cup.
Detailed description of the invention
Below in conjunction with drawings and Examples, the utility model is described further.
As shown in Figure 1, Figure 2, Figure 3 and Figure 4, a kind of device for the mixing of magnetic particle, comprises brshless DC motor 1, motor cabinet 2, the eccentric shaft 3 of band bearing, mixing rotating shaft 5 and mixing 7;
Described brshless DC motor 1 is arranged on described motor cabinet 2, the rotating shaft of brshless DC motor 1 is connected through the eccentric shaft 3 of motor cabinet 2 with band bearing, the eccentric shaft 3 of described band bearing, mixing rotating shaft 5 and mixing 7 is connected successively, and mixing head rest is lived reaction cup and rotated, and realizes mixing.
[evenly mixing device of the present utility model is integrated in Magneto separate mechanism, when reaction cup moves to mixing position, the mixing head be positioned at below reaction cup carries out eccentric rotary, thus makes reaction cup carry out eccentric rotary thus make the material in reaction cup carry out mixing mixing; ]
Also comprise climbing lifting mechanism, described climbing lifting mechanism comprises low order climbing block 8 and high-order climbing block 9;
Be arranged on the mixing 7 of mixing station between described low order climbing block and described high-order climbing block;
The peak of described low order climbing block and the minimum point of high-order climbing block all with mix parallel;
Reaction cup with in dial movement process along low order climbing block climb rise to mixing station mixing head on, climb to rise to get a glass station along high-order climbing block.
[rotary motion of climbing block and rotating disk forms climbing lifting mechanism, without the need to other lifting mechanism lifting reaction cup.】
The surface of described climbing lifting mechanism and the bottom arc surface of reaction cup tangent.
[along with the rotational response cup arc surface of rotating disk is along climbing block surface sliding, along with the face with climbing block raises, progressively lifting.】
Described mixing mechanism is provided with mixing seat 6, and mixing seat is fixed on motor cabinet 2; Described mixing rotating shaft, through mixing seat, between mixing seat and mixing rotating shaft, mixing rotating shaft is set with Compress Spring 4.
Described mixing mechanism is also provided with elastic pressuring plate external member 10, and described elastic pressuring plate external member 10 comprises elastic pressuring plate mount pad 81, extension spring 12, blind rivet 13, compressing tablet 14, second bearing pin 15 and adjustment screw 16;
Described elastic pressuring plate mount pad 11 is fixed on the installing plate 21 of Magneto separate mechanism 20, described compressing tablet 14 is connected with elastic pressuring plate mount pad 11 by bearing pin 15, described adjustment screw 16 screws in elastic pressuring plate mount pad 11 by described compressing tablet 14 jack-up, extension spring 12 one end is hooked on compressing tablet 14, and the other end hooks the blind rivet 13 be fixed on elastic pressuring plate mount pad 11;
Described compressing tablet offers adjustment hole 17, change the height of adjustment screw through adjustment hole 17; The diameter of described adjustment hole 17 is larger than the internal diameter of adjustment screw 16, and less than the external diameter of adjustment screw;
Described adjustment screw is holding screw.
[inner hexagon spanner is utilized to pass adjustment hole 17 turn adjustment screw, change the screw-in depth of adjustment screw in elastic pressuring plate mount pad, thus change the angle of compressing tablet and horizontal plane, namely the pivot angle of compressing tablet 14 is regulated, reaction cup is made to arrive mixing position smoothly along compressing tablet direction, in blending process, compressing tablet blocks reaction cup, prevents reaction cup in blending process from ejecting from putting hole.】
The lifting climbing block of ingehious design, can reaction cup segmentation lifting, first arrives mixing height, then is lifted to and gets cup height, getting the convenient pickup in cup position, without the need to other lifting mechanism lifting reaction cup.
By the setting of elastic pressuring plate mechanism, in blending process, effectively prevent reaction cup from ejecting from putting hole; Total is simple, easy for installation, can carry out simply with the magnetic separation system of chemiluminescence immune assay equipment and be combined closely, complete mixing function, without the need to peripheral hardware blending system separately again.
Be understandable that; for the person of ordinary skill of the art; can make other various corresponding change and distortion according to the technical solution of the utility model and technical conceive, and all these change and be out of shape the protection domain that all should belong to the accompanying claim of the utility model.
Claims (5)
1. the device for the mixing of magnetic particle, it is characterized in that, comprise brshless DC motor (1), motor cabinet (2), the eccentric shaft (3) being with bearing, mixing rotating shaft (5) and mixing head (7);
Described brshless DC motor (1) is arranged on described motor cabinet (2), the rotating shaft of brshless DC motor (1) is connected through the eccentric shaft (3) of motor cabinet (2) with band bearing, the eccentric shaft (3) of described band bearing, mixing rotating shaft (5) and mixing head (7) are connected successively, mixing head rest is lived reaction cup (30) and is rotated, and realizes mixing.
2. the device for the mixing of magnetic particle according to claim 1, is characterized in that, also comprise climbing lifting mechanism, and described climbing lifting mechanism comprises low order climbing block (8) and high-order climbing block (9);
Be arranged on the mixing head (7) of mixing station between described low order climbing block and described high-order climbing block;
The peak of described low order climbing block and the minimum point of high-order climbing block all with mix parallel;
Reaction cup with in dial movement process along low order climbing block climb rise to mixing station mixing head on, climb to rise to get a glass station along high-order climbing block.
3. according to claim 2 for magnetic particle mixing device, it is characterized in that, the surface of described climbing lifting mechanism and the bottom arc surface of reaction cup tangent.
4. the device for the mixing of magnetic particle according to claim 1, is characterized in that, described evenly mixing device is provided with mixing seat (6), and mixing seat is fixed on motor cabinet (2); Described mixing rotating shaft, through mixing seat, between mixing seat and mixing rotating shaft, mixing rotating shaft is set with Compress Spring (4).
5. the device for the mixing of magnetic particle according to claim 4, it is characterized in that, described evenly mixing device is also provided with elastic pressuring plate external member (10), described elastic pressuring plate external member (10) comprises elastic pressuring plate mount pad (11), extension spring (12), blind rivet (13), compressing tablet (14), the second bearing pin (15) and adjustment screw (16);
Described elastic pressuring plate mount pad (11) is fixed on the installing plate (21) of Magneto separate mechanism (20), described compressing tablet (14) is connected with elastic pressuring plate mount pad (1) by bearing pin (15), described adjustment screw (16) screws in elastic pressuring plate mount pad (11) by described compressing tablet (14) jack-up, extension spring (12) one end is hooked on compressing tablet (14), and the other end hooks the blind rivet (13) be fixed on elastic pressuring plate mount pad (11);
Described compressing tablet offers adjustment hole (17), change the height of adjustment screw through adjustment hole (17); The diameter of described adjustment hole (17) is larger than the internal diameter of adjustment screw (16), and less than the external diameter of adjustment screw;
Described adjustment screw is holding screw.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420557217.8U CN204134550U (en) | 2014-09-25 | 2014-09-25 | A kind of device for the mixing of magnetic particle |
| PCT/EP2015/072177 WO2016046403A1 (en) | 2014-09-25 | 2015-09-25 | Device for mixing magnetic particles and liquid in a reaction cup, adapted to be used in an apparatus for separation, washing and mixing of the contents of said reaction cup, in an immunoanalyzer system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420557217.8U CN204134550U (en) | 2014-09-25 | 2014-09-25 | A kind of device for the mixing of magnetic particle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204134550U true CN204134550U (en) | 2015-02-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420557217.8U Active CN204134550U (en) | 2014-09-25 | 2014-09-25 | A kind of device for the mixing of magnetic particle |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN204134550U (en) |
| WO (1) | WO2016046403A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105445481A (en) * | 2015-12-15 | 2016-03-30 | 苏州长光华医生物医学工程有限公司 | Reactant shaking device |
| CN106621985A (en) * | 2016-10-29 | 2017-05-10 | 芜湖市恒浩机械制造有限公司 | Four-station synchronous stirring device |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107870115A (en) * | 2017-10-26 | 2018-04-03 | 苏州立禾生物医学工程有限公司 | A kind of oscillating uniform device |
| CN107907700B (en) * | 2017-12-18 | 2023-09-05 | 杭州凯坤科技有限公司 | Full-automatic chemical luminescence analyzer |
| CN110514824A (en) * | 2019-09-24 | 2019-11-29 | 重庆科斯迈生物科技有限公司 | To suction chemical illumination immunity analysis instrument washing system |
| CN113198359A (en) * | 2021-04-30 | 2021-08-03 | 河南省人民医院 | Special medicine oscillator for nursing |
| CN113335930B (en) * | 2021-06-15 | 2022-11-11 | 中元汇吉生物技术股份有限公司 | Recovery device for reaction vessel |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3061280A (en) * | 1959-04-06 | 1962-10-30 | Kraft Scient Corp | Apparatus for mixing fluent material |
| JPS6081B2 (en) * | 1982-07-26 | 1985-01-05 | サヌキ工業株式会社 | automatic extraction device |
| US4845025A (en) * | 1987-11-10 | 1989-07-04 | Coulter Corporation | Biological sample mixing apparatus and method |
| ATE74795T1 (en) * | 1988-05-09 | 1992-05-15 | Gene Trak Systems | DEVICE FOR MIXING AT LEAST ONE AQUEOUS SUBSTANCE. |
| US5813759A (en) * | 1996-07-03 | 1998-09-29 | Dade International Inc. | Method and apparatus for vortex mixing using centrifugal force |
| CN103599898B (en) * | 2013-10-29 | 2015-11-25 | 北京利德曼生化股份有限公司 | Full-automatic chemiluminescence immunoassay analysis meter magnetic bead cleaning device |
-
2014
- 2014-09-25 CN CN201420557217.8U patent/CN204134550U/en active Active
-
2015
- 2015-09-25 WO PCT/EP2015/072177 patent/WO2016046403A1/en active Application Filing
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105445481A (en) * | 2015-12-15 | 2016-03-30 | 苏州长光华医生物医学工程有限公司 | Reactant shaking device |
| CN105445481B (en) * | 2015-12-15 | 2017-12-12 | 苏州长光华医生物医学工程有限公司 | A kind of reactant oscillating uniform device |
| CN106621985A (en) * | 2016-10-29 | 2017-05-10 | 芜湖市恒浩机械制造有限公司 | Four-station synchronous stirring device |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016046403A1 (en) | 2016-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20211231 Address after: No. 15, Avenue II, torio Emmanuelle, Milan, Italy Patentee after: Genetic Technology Co.,Ltd. Address before: 518101 No. 128, floor 1, zone 1, block B, famous and excellent product procurement center, 168 Baoyuan Road, Bao'an District, Shenzhen, Guangdong Province Patentee before: ALTERGON ITALIA S.R.L. |
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| TR01 | Transfer of patent right |