The two high pressure cylinder homogenization integrated device of a kind of coaxial line
Technical field
The utility model relates to a kind of cell crushing instrument pressurization homogenization device, particularly relates to the two high pressure cylinder homogenization integrated device of a kind of coaxial line.
Background technology
Cell breaking technology refers to and utilizes outside destroy cytolemma and cell walls, the technology making entocyte comprise object product component to discharge, and is the basis of the nonsecreting type biochemical substances (product) of synthesis in separation and purification cell.In conjunction with the major progress in recombinant DNA technology and tissue culture technique, think that very unobtainable protein now can scale operation in the past.Develop various kinds of cell breaking method at present, to adapt to different purposes and the fragmentation of dissimilar cell walls.Breaking method can be advised and be received as mechanical process and the large class of on-mechanical method two.And the equipment used by mechanical process also has a variety of, and conventional equipment is super high pressure cell crusher, this conventional equipment tool in the fragmentation of biomass cells, medicine, food, milk, makeup, chemical materials, nano material etc., fine dispersion, particle nanometer, emulsification processing has been widely used.The shortcoming that this conventional super high pressure cell crusher exists is: (1) adopts single axle master cylinder, and energy consumption is high; (2) liquid outlet of its pressurization homogenization device is driveed on top, and fluid has some setbacks, and easily has residual; (3) tensimeter of its pressurization homogenization device is directly connected with high pressure chest, high pressure gauge is frequently pulsed, thus easily damages; (4) high-pressure energy release easily produces temperature rise; (5) high pressure homogeneous valve easily weares and teares.Therefore a kind of new pressurization homogenization device of utility model is necessary, to improve aforementioned drawback.
Utility model content
The purpose of this utility model is to provide the two high pressure cylinder homogenization integrated device of a kind of coaxial line, and compact construction, saves part, be beneficial to miniaturization, and energy-conservation.
For achieving the above object, the utility model provides a kind of coaxial line two high pressure cylinder homogenization integrated device, comprise long-cylinder, main adapter sleeve, high pressure cylinder homogeneous main body, attached female connector and short oil cylinder, described main adapter sleeve, high pressure cylinder homogeneous main body, attached female connector and short oil cylinder have two respectively, two described main adapter sleeves, two high pressure cylinder homogeneous main bodys, two attached female connectors and two short oil cylinders are symmetricly set on the two ends of described long-cylinder respectively and all install with long-cylinder coaxial inner conductor, each described high pressure cylinder homogeneous main body connects into entirety by adapter sleeve main described in one and described long-cylinder, each described high pressure cylinder homogeneous main body connects into entirety by female connector attached described in one and corresponding short oil cylinder, the piston rod that alternately can stretch out from its two ends is provided with in described long-cylinder, the two ends of described piston rod connect the pressured column stopper rod in the high pressure chest of high pressure cylinder homogeneous main body described in respectively, homogenizing valve in the inner chamber of each described high pressure cylinder homogeneous main body connects the push rod of short oil cylinder described in respectively
Due to two main adapter sleeves, two high pressure cylinder homogeneous main bodys, two attached female connectors and two short oil cylinders are symmetricly set on the both sides of long-cylinder and install with long-cylinder coaxial inner conductor, thus compact construction, volume is little, be conducive to miniaturization Design, and long-cylinder has the piston rod that alternately can stretch out from its two ends, thus the high pressure cylinder homogeneous body of work on both sides that makes that can replace carries out fragmentation to cell, the high pressure cylinder homogenization integrated device of the use single axle long-cylinder compared to existing technology, the two high pressure cylinder homogenization integrated device economize on electricity of this coaxial line obviously, at least can save energy 30%-40%, energy consumption is reduced greatly.
As further improvement of the utility model, the high pressure chest tail end top of each described high pressure cylinder homogeneous main body is provided with the opening for feed be communicated with high pressure chest, the left side of each described high pressure cylinder homogeneous main body is provided with the tensimeter Link Port be communicated with high pressure chest, the right side of each described high pressure cylinder homogeneous main body be also provided with high pressure cylinder homogeneous main body go out the liquid outlet that sample chamber is communicated with, described liquid outlet with go out to be connected bottom sample chamber and vertically downward and be connected stainless steel spiral coil cooling tube.This structure compared to existing technology middle liquid outlet opens the mode at high pressure cylinder homogeneous body top, and fluid resistance is less, and fluid is more smooth and easy, not easily remains in high pressure cylinder homogeneous main body.
Further improve as of the present utility model, each described opening for feed is connected with an integrated feedstock device, each described integrated feedstock device comprises the second check valve and bin stock cup, the import of the valve seat of described second check valve is directly connected with the bottom of described bin stock cup, the outlet of the valve body of each described second check valve is connected with corresponding opening for feed, and the valve body of described second check valve and described bin stock cup are one-piece construction.This structure can be convenient to sample introduction and exhaust, the structure of the two high pressure cylinder homogenization integrated device of coaxial line can also be made compacter, thus be conducive to miniaturization Design, and can also reduce the loss of material in fragmentation, and easy to operate.
Further improve as of the present utility model, be provided with the first check valve in each described tensimeter Link Port, a part for the valve body of each described first check valve is positioned at corresponding high pressure cylinder homogeneous main body and forms one-piece construction with high pressure cylinder homogeneous main body.This structure can make the structure of the two high pressure cylinder homogenization integrated device of coaxial line compacter, thus is conducive to miniaturization Design, but also can prevent high pressure gauge from pulsing, and avoids high pressure gauge to damage.
Further improve as of the present utility model, each axial line of described high pressure cylinder homogeneous main body and the axial line of the first corresponding check valve and the second check valve intersect vertically.This structure is conducive to tensimeter and accurately detects pressure in high pressure cylinder homogeneous main body, and is conducive to miniaturization Design, but also is more conducive to tensimeter and accurately detects pressure in pressurization homogenization integrated device.
Further improving as of the present utility model, is plane contact sealing between the spool of each described first check valve and valve seat, is also plane contact sealing between the spool of each described second check valve and valve seat.This structure is easy to process, and the good operating stability of the first check valve and the second check valve, long service life.
Improve as another kind of the present utility model, the top of described main adapter sleeve offers subjectivity and examines adjustment window, and bottom offers water cycle window, and the top of described attached female connector offers attached observation adjustment window, and bottom offers attached water cycle window.This structure can conveniently carry out observing and adjust and cooling water circulation.
By following description also by reference to the accompanying drawings, the utility model will become more clear, and these accompanying drawings are for explaining embodiment of the present utility model.
Accompanying drawing explanation
Fig. 1 is the front view of the two high pressure cylinder homogenization integrated device of coaxial line of the present utility model.
Fig. 2 is the left view of the two high pressure cylinder homogenization integrated device of coaxial line of the present utility model.
Fig. 3 is the sectional view of high pressure cylinder homogeneous main body and the first check valve.
The sectional view of the integrated feeding unit of Fig. 4.
Embodiment
With reference now to accompanying drawing, describe embodiment of the present utility model, element numbers similar in accompanying drawing represents similar element.
Please refer to Fig. 1-Fig. 4, the two high pressure cylinder homogenization integrated device of coaxial line of the present utility model comprises the main adapter sleeve of long-cylinder 1, two 2, two high pressure cylinder homogeneous main bodys 3, two attached female connectors 4 and two short oil cylinders 5.The two ends of described long-cylinder 1 are connected to one end of a high pressure cylinder homogeneous main body 3 respectively by a main adapter sleeve 2, the other end of each high pressure cylinder homogeneous main body 3 is connected to a short oil cylinder 5 by an attached female connector 4.Described long-cylinder 1, main adapter sleeve 2, high pressure cylinder homogeneous main body 3, to be all threaded connection between attached female connector 4 and short oil cylinder 5, and the described main adapter sleeve of long-cylinder 1, two 2, two high pressure cylinder homogeneous main bodys 3, two attached female connectors 4 and two short oil cylinder 5 coaxial inner conductors are installed.
Further illustrate, in described long-cylinder 1, be provided with the piston rod that alternately can stretch out from its two ends, in described short oil cylinder 5, be provided with the push rod 51 that can stretch out from its one end.
The top of each described main adapter sleeve 2 offers subjectivity and examines adjustment window 21, and bottom offers water cycle window 22, and the top of each described attached female connector 4 offers attached observation adjustment window 41, and bottom offers attached water cycle window 42.Described subjectivity examines adjustment window 21 and attached observation adjustment window 41 can conveniently carry out observing and adjusting, and described water cycle window 22 and attached water cycle window 42 can facilitate cooling water circulation.
Have the pressured column stopper rod 31 of reciprocally movement in the high pressure chest of each described high pressure cylinder homogeneous main body 3, the two ends of the piston rod of described long-cylinder 1 connect the pressured column stopper rod 31 in the high pressure chest of high pressure cylinder homogeneous main body 3 described in respectively; Homogenizing valve is also had in the inner chamber be communicated with high pressure chest of each described high pressure cylinder homogeneous main body 3, homogenizing valve in the inner chamber of each described high pressure cylinder homogeneous main body 3 connects the push rod 51 of short oil cylinder 5 described in respectively, namely the both sides of high pressure cylinder homogeneous main body 3 adopt two-way cylinder, thus can greatly simplify traditional complete machine structure, reduce web member and check valve, reduce failure rate, be convenient to inspection and accessory maintain and replace.Described long-cylinder 1 is the master cylinder that pressured column stopper rod 31 moves, and described short oil cylinder 5 is attached oil cylinders of controlled fragmentation pressure.The left side of each described high pressure cylinder homogeneous main body 3 is provided with the tensimeter Link Port be communicated with high pressure chest, is provided with the first check valve 6 in described tensimeter Link Port.The high pressure chest tail end top of each described high pressure cylinder homogeneous main body 3 is provided with the opening for feed be communicated with high pressure chest, each described opening for feed is connected with integrated feedstock device 7, thus make integrated feedstock device 7 be connected to the tail end top of corresponding high pressure chest, thus be convenient to sample introduction and exhaust.The right side of each described high pressure cylinder homogeneous main body 3 is also provided with liquid outlet 9, described liquid outlet 9 with go out to be connected bottom sample chamber and vertically downward and be connected stainless steel spiral coil cooling tube 8 (part for stainless steel spiral coil cooling tube 8 is only shown in Fig. 1 and Fig. 2), thus resistance is little, fluid is smooth and easy, not easily remains in high pressure cylinder homogeneous main body.
Illustrate further, each described first check valve 6 comprises the first valve body 61, first spool 62 and the first valve seat 63.Described first spool 62 and described first valve seat 63 are positioned at the passage of described first valve body 61, and are plane contact sealing between described first spool 62 and the first valve seat 63, thus good operating stability, long service life.A part for each described first valve body 61 is positioned at corresponding high pressure cylinder homogeneous main body 3 and forms one-piece construction with described high pressure cylinder homogeneous main body 3, another part is positioned at outside high pressure cylinder homogeneous main body 3, thus the stability of the two high pressure cylinder homogenization integrated device of coaxial line can be improved, prevent high pressure gauge from pulsing, high pressure gauge is avoided to damage, and compact construction, be conducive to miniaturization Design.
Each described integrated feedstock device 7 comprises the second check valve 71 and bin stock cup 72, the axial line of the axial line of each described high pressure cylinder homogeneous main body 3 and the first described check valve, the second check valve 71 intersects vertically, thus be more conducive to tensimeter and accurately detect pressure in pressurization homogenization integrated device, and be conducive to miniaturization Design.Each described second check valve 71 comprises the second valve body 71a, the second spool 71b and the second valve seat 71c.Described second spool 71b and the second valve seat 71c is positioned at the passage of described second valve body 71a, and is plane contact sealing between described second spool 71b and the second valve seat 71c, thus good operating stability, long service life.Described second valve body 71a and described bin stock cup 72 are one-piece construction.Import 711 is provided with in described second valve seat 71c, described import 711 is directly connected with the bottom of described bin stock cup 72, the outlet of each described second valve body 71a is connected with corresponding opening for feed, thus does not need long connecting pipeline, can greatly reduce the loss of sample materials in fragmentation; Meanwhile, directly can insert exhaust with draw point from bin stock cup 72 when the second check valve 71 is vented, operation is very easy easily.Described bin stock cup 72 is provided with bowl cover 73, and described bowl cover 73 is socketed with bin stock cup 72 and is connected, and also can be threaded, and is taken off by described bowl cover 73 during to facilitate and to add sample and described second check valve 71 exhaust gas inside.Described bowl cover 73 is provided with the quick coupling 74 for Rapid Cleaning, to facilitate bin stock cup 72 cleaning operation.
More than in conjunction with most preferred embodiment, the utility model is described, but the utility model is not limited to the embodiment of above announcement, and should contain various carry out according to essence of the present utility model amendment, equivalent combinations.