CN204072169U - Endometrium harvester - Google Patents
Endometrium harvester Download PDFInfo
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- CN204072169U CN204072169U CN201420530113.8U CN201420530113U CN204072169U CN 204072169 U CN204072169 U CN 204072169U CN 201420530113 U CN201420530113 U CN 201420530113U CN 204072169 U CN204072169 U CN 204072169U
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- endometrium
- outer sheath
- tube core
- piston tube
- harvester
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Abstract
The utility model discloses an Endometrium harvester, described endometrium harvester comprises the outer sheath of hollow, piston tube core and handle, the internal diameter of outer sheath and the external diameter of piston tube core match, piston tube core is inserted the hollow bulb of outer sheath and is contacted with wall seamless in outer sheath, one end connecting handle of piston tube core, drawing handle makes to slide in the hollow bulb of piston tube core sheath pipe outside; Wherein, with outer sheath top for starting point is provided with several apertures to the wall of a pipe range of first three point.Endometrium harvester of the present utility model can not be blocked by endometrium when gathering endometrium, the endometrium amount collected is more, effectively ensure that and can isolate inner membrance glandular epithelium/mesenchyme Derived Stem Cells from the endometrium collected, satisfy the demands.This device also can be used for clinical when being suspected to have endometrial biopsy and the carcinoma of endometrium examination of Endometrial Diseases Endometrium draw materials, and replace diagnostic curettage.
Description
Technical field
This utility model relates to an Endometrium harvester, particularly relates to a kind of harvester of Endometrial stem cell.
Background technology
Stem cell, as the pluripotent cell with self replication and directed differentiation ability, day by day demonstrates powerful clinical application potential in mankind's defying age and disease treatment.The main source of current human stem cell is the embryonic stem cell in Cord blood, umbilical cord mesenchyma and amnion mesenchymal source and the bone marrow stem cell of peripheral blood and derived from bone marrow, and these two kinds of stem cell are limited owing to originating, and become scarce resource.Current research finds that Endometrial stem cell is the pluripotent stem cell that human body number is maximum, reach 30 times of bone marrow stem cell, its in-vitro multiplication ability is strong, differentiation potential is large, only 24 hours doubling time, can breed 390 times, go down to posterity 50 times, and immunogenicity is low, substantially without allosome immunologic rejection, do not cause chromosome disorder and tumor generation etc., be therefore considered to the human stem cell of most application prospect.
Endometrium increases organ the most active in human body, is divided into functional layer and basal layer.The former is made up of glandular epithelium and interstitial, changes with Estrogen and progestin in menstrual cycle change of breeding, secrete and come off; Latter wound repairing, hypertrophy after menstrual phase inner membrance comes off form new functional layer.The endometrium of post menopausal and low estrogen women substitutes through exogenous hormones can there is the hypertrophy identical with free period, secrete and change with coming off.In normal menstrual cycle, under the adjustment of hormone, stem cell also periodically goes through stable phase, proliferation period and stage idiophase.Therefore, the stem cell being positioned at endometrium and position, muscle layer boundary and inner membrance basal layer is the driving source that endometrial proliferation is repaired.Collect, be separated the Endometrial stem cell entering the multiplicative stage, In vitro culture can obtain the pluripotent stem cell in a large number with hyperproliferation potential and multiple therapeutical effect, it can be used for defying age, also can be used as that intrauterine is lepthymenia, the treatment means of intimal lesion reparation and endometrium canceration, in the situations such as major disease and unexpected grievous injury such as women's generation tumor, diabetes, Parkinson's disease, heart disease, apoplexy and Liver and kidney, autologous stem cells treatment can be carried out.Except for me, Endometrial stem cell also can be its father and mother, children, relatives and other people health care is provided.
High value is possessed in view of the hyperproliferation of Endometrial stem cell and differentiation potential use, therefore the collection of Endometrial stem cell also just becomes very crucial, for collecting Endometrial stem cell, harvester is normally utilized to gather endometrium, then be separated to obtain inner membrance glandular epithelium/mesenchyme Derived Stem Cells to collecting endometrium, again intimal epithelium/mesenchyme Derived Stem Cells is carried out In vitro culture, goes down to posterity, obtaining can for treating or the stem cell of medicine adornment.But the collection tube of existing endometrium collector is often blocked, the endometrium amount collected is little, causes isolating inner membrance glandular epithelium/mesenchyme Derived Stem Cells in the endometrium sometimes collected, is difficult to satisfy the demands.
Utility model content
For the problems referred to above, the technical problem that this utility model mainly solves is to provide an Endometrium harvester, described endometrium harvester can not be blocked by endometrium when gathering endometrium, the endometrium amount collected is more, effectively ensure that and can isolate inner membrance glandular epithelium/mesenchyme Derived Stem Cells from the endometrium collected, satisfy the demands.
For solving the problems of the technologies described above, the technical solution adopted in the utility model is: provide an Endometrium harvester, described endometrium harvester comprises the outer sheath of hollow, piston tube core and handle, the internal diameter of described outer sheath and the external diameter of described piston tube core match, described piston tube core is inserted the hollow bulb of described outer sheath and is contacted with wall seamless in described outer sheath, one end of described piston tube core connects described handle, and handle described in push-and-pull makes to slide in the hollow bulb of described piston tube core sheath pipe outside; Wherein, with described outer sheath top for starting point is provided with several apertures to the wall of a pipe range of first three point.
The using method of this utility model endometrium harvester is: piston tube core is pushed the hollow bulb of outer sheath by (1), gently inserts uterine cavity through cervix uteri is fond of food that is not salty, (2) make outer sheath sidewall contact palace wall, left and right all directions adherent rotation gently forwards, backwards, makes endometrium be separated with palace wall, (3) top of outer sheath reaches bottom palace, outside slowly pull piston tube core, to be separated with palace wall and the endometrium contacted with outer sheath top is inhaled into the hollow bulb of outer sheath, now, outer sheath top is that the aperture that starting point is arranged on the wall of a pipe range of first three point ensure that outer sheath also makes outer sheath top still keep appropriate negative pressure while not blocked, internal film tissue can continue the hollow bulb being inhaled into outer sheath, harvester is slowly outwards exited in suction limit, limit, until cervix uteri internal orifice level, now the hollow bulb of whole outer sheath is full of endometrium, take out harvester, (4) promoting piston tube core is pushed in the tissue preserration liquid of aseptic pre-cooling by the endometrium in the hollow bulb of outer sheath, 4 DEG C of cryopreservation, Nei Song culturing room process in 2 hours.
Preferably, described outer sheath is straight tube.Trocar sheath is straight tube, and the uterus being suitable for horizontal position uses.
Preferably, the top of described outer sheath is round and smooth.The top of trocar sheath is round and smooth, not easy damaged uterine cavity mucosal tissue when trocar sheath is inserted in uterine cavity.
Preferably, the bottom cover jug of described outer sheath.The bottom cover jug of outer sheath, when using described endometrium harvester, a hand push of operator draws described handle, and another hands pinches handle, and piston tube core described in push-and-pull makes it slide in the hollow bulb of outer sheath so easily.
Preferably, the diameter of described aperture is 1.5 millimeters.Pull described piston tube core aspirate endometrium time, the aperture that diameter is 1.5 millimeters ensure better described outer sheath not blocked while described outer sheath top still keep appropriate negative pressure, internal film tissue can continue the hollow bulb being inhaled into outer sheath.
Preferably, described outer sheath is straight pipe, long 20 centimetres, and external diameter is from 3 millimeters to 6 millimeters, and often increasing by 0.5 millimeter is a yardage.Outer sheath is straight pipe, long 20 centimetres, the thinnest person of external diameter 3 millimeters, and such setting makes outer sheath just can enter in cavity of uterus from cervix uteri mouth without expansion palace, can not produce injury to cervix uteri mouth.External diameter is from 3 millimeters to 6 millimeters, and often increasing by 0.5 millimeter is a yardage, to be applicable to select through pregnant/puerpera's cervix uteri mouth pine person.
Preferably, the foraminate outer sheath part of described tool is set to curved shape.The foraminate outer sheath part of trocar sheath tool is set to curved shape, is more convenient for collecting the endometrium at angle, palace, left and right like this.
The beneficial effects of the utility model are: the collection tube being different from present endometrium collector is often blocked, the situation that the endometrium amount collected is little, endometrium harvester of the present utility model comprises the outer sheath of hollow, piston tube core and hands handle, the internal diameter of described outer sheath and the external diameter of described piston tube core match, described piston tube core is inserted the hollow bulb of described outer sheath and is contacted with wall seamless in described outer sheath, one end of described piston tube core connects described hands handle, when pulling described handle to make to slide in the hollow bulb of described piston tube core sheath pipe outside during suction endometrium, described outer sheath top is that aperture that starting point is arranged on the wall of a pipe range of first three point can also make outer sheath top keep appropriate negative pressure make outer sheath not blocked while, internal film tissue can continue the hollow bulb being inhaled into outer sheath, the hollow bulb of whole outer sheath is made to be full of endometrium.
This device also can be used for clinical when being suspected to have endometrial biopsy and the carcinoma of endometrium examination of Endometrial Diseases Endometrium draw materials, and replace diagnostic curettage.
Accompanying drawing explanation
The endometrium harvester sectional view that Fig. 1 provides for this utility model embodiment;
The endometrium harvester sectional view that Fig. 2 provides for another embodiment of this utility model.
Detailed description of the invention
Below in conjunction with drawings and Examples, this utility model is described in detail.
Embodiment 1
Refer to Fig. 1, endometrium harvester comprises the outer sheath 1 of hollow, piston tube core 2 and handle 3.Outer sheath 1 is straight pipe, and matter is tough, long 20 centimetres, external diameter 3 millimeters.Outer sheath 1 top is round and smooth, with outer sheath 1 top for starting point is provided with to the wall of a pipe range of first three point the aperture 101 that several diameters are 1.5 millimeters.The internal diameter of outer sheath 1 and the external diameter of piston tube core 2 match, piston tube core 2 is inserted the hollow bulb of outer sheath 1 and is contacted with wall seamless in outer sheath 1, between can enter without gas, one end connecting handle 3 of piston tube core 2, drawing handle 3 just can make piston tube core 2 slide in the hollow bulb of outer sheath 1.Piston tube core 2 is the cylindrical tube cores be made up of hard plastic, is connected with handle 3, and piston tube core 2 is isometric with outer sheath 1; Piston tube core 2 is inserted outer sheath 1, and when handle 3 reaches outer sheath 1 bottom margin, the top of piston tube core 2 is just concordant with outer sheath 1 top.
The using method of this utility model endometrium harvester is: piston tube core 2 is pushed the hollow bulb of outer sheath 1 by (1), gently inserts uterine cavity through cervix uteri is fond of food that is not salty, (2) make outer sheath 1 sidewall contact palace wall, left and right all directions adherent rotation gently forwards, backwards, makes endometrium be separated with palace wall, (3) top of outer sheath 1 reaches bottom palace, be pulled outwardly handle 3 slowly pull piston tube core 2, to be separated with palace wall and the endometrium contacted with outer sheath 1 top is inhaled into the hollow bulb of outer sheath 1, now, outer sheath 1 top is that the aperture 101 that starting point is arranged on the wall of a pipe range of first three point ensure that outer sheath 1 also makes outer sheath 1 top still keep appropriate negative pressure while not blocked, internal film tissue can continue the hollow bulb being inhaled into outer sheath 1, harvester is slowly outwards exited in suction limit, limit, until cervix uteri internal orifice level, now the hollow bulb of whole outer sheath 1 is full of endometrium, take out harvester, (4) promoting piston tube core 2 is pushed in the tissue preserration liquid of aseptic pre-cooling by the endometrium in the hollow bulb of outer sheath 1,4 DEG C of cryopreservation, Nei Song culturing room process in 2 hours.
Embodiment 2
Refer to Fig. 2, the endometrium harvester sectional view that another embodiment of this utility model provides, as different from Example 1, endometrium harvester of the present utility model has leader 4 at the bottom of outer sheath 1 cover, and other structures are identical with embodiment 1.When using endometrium harvester of the present utility model, a hand push handle 3 of operator, another hands pinches handle 4, and push-and-pull piston tube core 2 makes it slide in the hollow bulb of outer sheath 1 so more easily.
Those skilled in the art do not depart from essence of the present utility model and spirit, various deformation scheme can be had to realize this utility model, the foregoing is only the better feasible embodiment of this utility model, not thereby interest field of the present utility model is limited to, the equivalent structure change that all utilization this utility model description and accompanying drawing content are done, is all contained within interest field of the present utility model.
Claims (7)
1. an Endometrium harvester, it is characterized in that, described endometrium harvester comprises the outer sheath of hollow, piston tube core and handle, the internal diameter of described outer sheath and the external diameter of described piston tube core match, described piston tube core is inserted the hollow bulb of described outer sheath and is contacted with wall seamless in described outer sheath, one end of described piston tube core connects described handle, and handle described in push-and-pull makes to slide in the hollow bulb of described piston tube core sheath pipe outside; Wherein, with described outer sheath top for starting point is provided with several apertures to the wall of a pipe range of first three point.
2. endometrium harvester according to claim 1, is characterized in that, described outer sheath is straight tube.
3. endometrium harvester according to claim 1, is characterized in that, the top of described outer sheath is round and smooth.
4. endometrium harvester according to claim 1, is characterized in that, the bottom cover jug of described outer sheath.
5. endometrium harvester according to claim 1, is characterized in that, the diameter of described aperture is 1.5 millimeters.
6. the endometrium harvester according to any one of claim 1 ~ 5, is characterized in that, described outer sheath is straight pipe, long 20 centimetres, and external diameter is from 3 millimeters to 6 millimeters, and often increasing by 0.5 millimeter is a yardage.
7. endometrium harvester according to claim 1, is characterized in that, the foraminate outer sheath part of described tool is set to curved shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420530113.8U CN204072169U (en) | 2014-09-16 | 2014-09-16 | Endometrium harvester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420530113.8U CN204072169U (en) | 2014-09-16 | 2014-09-16 | Endometrium harvester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204072169U true CN204072169U (en) | 2015-01-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420530113.8U Expired - Fee Related CN204072169U (en) | 2014-09-16 | 2014-09-16 | Endometrium harvester |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204072169U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106344131A (en) * | 2016-08-31 | 2017-01-25 | 郑州大学第附属医院 | Ovarian tissue section pushing device |
-
2014
- 2014-09-16 CN CN201420530113.8U patent/CN204072169U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106344131A (en) * | 2016-08-31 | 2017-01-25 | 郑州大学第附属医院 | Ovarian tissue section pushing device |
| CN106344131B (en) * | 2016-08-31 | 2019-06-28 | 郑州大学第一附属医院 | A kind of ovary tissue slice driving means |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150107 Termination date: 20170916 |
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| CF01 | Termination of patent right due to non-payment of annual fee |