CN106344131A - Ovarian tissue section pushing device - Google Patents
Ovarian tissue section pushing device Download PDFInfo
- Publication number
- CN106344131A CN106344131A CN201610768726.9A CN201610768726A CN106344131A CN 106344131 A CN106344131 A CN 106344131A CN 201610768726 A CN201610768726 A CN 201610768726A CN 106344131 A CN106344131 A CN 106344131A
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- China
- Prior art keywords
- outer tube
- core
- tissue section
- ovary tissue
- pushing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/42—Gynaecological or obstetrical instruments or methods
- A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Abstract
An ovarian tissue section pushing device comprises a pushing core and an outer tube, wherein the outer tube coaxially sleeves the outside of the pushing core; the length of the pushing core is greater than or equal to the length of the outer tube; one end of the pushing core is fixedly connected with a handle; a projection is arranged at the other end of the pushing core and is positioned in the outer tube; and the projection is in sliding fit with the outer tube in a sealed manner. The ovarian tissue section pushing device is simple in structure and convenient to use, and transplanting time of an ovarian tissue section is greatly saved; and because the exposure time of the ovarian tissue section out of the body is short, recovery of an ovarian tissue and fertility of a postoperative patient is facilitated.
Description
Technical field
The present invention relates to tissue transplantation's instrument field, especially relate to a kind of ovary tissue section pusher.
Background technology
Premature ovarian failure refers to the ovarian function failure that women occurred before 40 years old, and Female in child bearing period therefore loses its reproduction and interior
Secretory function, leads to infertile and perimenopausal symptom too early, incidence rate is about 1%.With late marriage and childbirth and national two tire political affairs
The relieving of plan, the quantity of the patient that cannot give birth to because of premature ovarian failure sharply increases.
Research display, ovary tissue transplanting can recover reproductive performance and the endocrine function of chain reaction in patients with premature ovarian.At present,
More ovary tissue is clinically applied to transplant the female patient being mainly used in malignant tumor, before starting chemicotherapy,
Still be there is the temporary transient freezen protective of ovary tissue of normal function, after treatment is finished, then ovary tissue put back in the patient,
To recover endocrine and the reproductive function of her ovaries.
And for chain reaction in patients with premature ovarian although ovarian function exhaustion, but still suffer from residual on a small quantity in a lot of her ovaries
The dormancy primordial follicle deposited.Patient side ovary is excised by laparoscopic technique, is then cut into the section of 1 × 1mm, apply pten
Primordial follicle (the in vitro activation of " dormancy " in gene inhibitor and pi3 kinase activator thing activation ovary tissue
Of dormant follicles, iva), then chain reaction in patients with premature ovarian tunica serosa tubae uterinae is transplanted back in ovary tissue section again
Under, after induced ovulation, obtain mature egg, obtain the hope of fertility after vitro fertilization-embryo implanting.
At present, conventional ovary transplantation technology is that ovary tissue is cut into slices (about 1.1-1.5mm) by laparoscopic use abdomen
Hysteroscope tissue forcepies are piecemeal to be put back in the patient one by one, generally once inserts ovary tissue section about 90- in the patient
120, therefore very time-consuming, about need 2-4 hour, and ovary tissue section in vitro open-assembly time length can affect postoperative
The effect of ovarian function recovery.
Content of the invention
The purpose of the present invention is to be to overcome disadvantages mentioned above, provides a kind of ovary tissue section pusher, ovary group
Knit section to put in above-mentioned pusher, be then injected into transplantation site, structure is simple, easy to use, has saved ovary tissue
The transplant time of section, due to ovary tissue section, open-assembly time is short in vitro, is more beneficial for ovary tissue and postoperative patient life
Educate the recovery of ability.
For reaching above-mentioned purpose, the present invention adopts the following technical scheme that:
A kind of ovary tissue section pusher, including pushing core and outer tube, outer coaxial tube is sheathed on the outside pushing core, pushes
The length of core is more than or equal to the length of outer tube, and the one end pushing core is fixedly connected with handle, and the other end pushing core is conformed with
Portion, in outer tube, jut is slidably matched with the outer seal of tube for protruding part.
Preferably, the described external stability pushing core is provided with spacing preiection, spacing preiection is string configuration, and limits
Position is raised, and along pushing the axially arranged of core, spacing preiection is multiple along the even circumferential setting pushing core, the top of spacing preiection with
The inwall of outer tube is slidably matched.
Preferably, spacing preiection is near jut one end, and the length of spacing preiection is less than the length of outer tube.
Preferably, described outer tube is fixedly connected with spacing catch, the centre of spacing catch at handle one end open
Have a spacing hole, push core and pass from spacing hole, spacing hole with diameter greater than the diameter pushing core and outer less than lobe
Footpath.
Preferably, outer tube is connected to grip part near one end fixed cover of handle.
Preferably, the diameter with diameter greater than outer tube of described handle.
Preferably, described jut is oval shape structure.
Preferably, described outer tube is provided with graduation mark at the position of jut, graduation mark sets along the axial direction of outer tube
Put.
Preferably, the outside of described handle is provided with anti-skid bulge.
Preferably, the length of described outer tube is 35cm-40cm, internal diameter is 1.5mm-2mm, and the length of described push core is
35cm-45cm, a diameter of 1mm-1.5mm, described push core is than outer pipe range 2mm.
The invention has the benefit that 1, structure is simple, easy to use, when greatling save the transplanting that ovary tissue is cut into slices
Between, due to ovary tissue section, open-assembly time is short in vitro, is more beneficial for the recovery of ovary tissue and postoperative patient fertility；
2nd, the end pushing core is provided with jut, quickly tissue slice not only can be pushed to transplantation site, will not simultaneously
Scratch its hetero-organization of transplantation site, play a protective role；
3rd, the outside of outer tube is provided with graduation mark, is easy to accurately arrange the distance pushing core, prevents from pushing excessive air；
4th, the end pushing core is provided with jut, and jut is slidably matched with the inner wall sealing of outer tube, prevents the air of outside
Enter transplantation site it is ensured that the sterile working of transplantation site；
5th, the outside pushing core is provided with spacing preiection, not only can guarantee that push core will not bend change during pushing
Shape, and ensure that push core will not double swerve in outer tube；
6th, outer tube is provided with spacing catch at handle one end open, and push core can be prevented to be completely pulled out of from outer tube.
Brief description
Fig. 1 is the structural representation of the present invention；
Fig. 2 is the a-a sectional view of Fig. 1；
Fig. 3 is the push cored structure schematic diagram of the present invention；
Fig. 4 is the b-b sectional view of Fig. 3；
Fig. 5 is the sectional view of outer tube of the present invention.
Specific embodiment
For the ease of the understanding of those skilled in the art, with reference to embodiment and accompanying drawing, the present invention is done further
Bright, the content not limitation of the invention that embodiment refers to.
As Figure 1-5, a kind of ovary tissue section pusher, including pushing core 1 and outer tube 2, outer tube 2 is coaxially sheathed
In the outside pushing core 1, the length pushing core 1 is more than or equal to the length of outer tube 2, accurate in order to perform the operation, and the present embodiment edge is outer
Graduation mark 6 is provided with the axial direction of pipe 2, outer tube 2 is made up of transparent material.Outer tube 2 arranges limited at handle 3 one end open
Position catch 9, the centre of spacing catch 9 has spacing hole, pushes core 1 and passes from spacing hole, the size of spacing hole is more than
Push diameter and the external diameter less than jut 4 of core 1, spacing catch 9 not only can ensure to push core 1 direction during pushing
Stable, push core 1 can be prevented to be completely pulled out of from outer tube 2 simultaneously.
The one end pushing core 1 is fixedly connected with handle 3, for the ease of operator's operation, the outside of the handle 3 of the present embodiment
It is provided with anti-skid bulge 8, the diameter with diameter greater than outer tube 2 of handle 3, the other end pushing core 1 is conformed with portion 4, does not use
When jut 4 be located at push core 1 inside, the jut 4 of the present embodiment be arranged to oval shape structure it is also possible to be arranged to justify
The material such as spherical structure, it would however also be possible to employ elastomeric material is made, such as medical silica-gel, silicone rubber.Jut 4 is sealed with outer tube 2
It is slidably matched, jut 4 is in close contact with the internal diameter of outer tube 2, and jut 4 slides in the presence of pushing core 1 in outer tube 2.
Hold outer tube 2 for convenience, be connected to grip part 5 in outer tube 2 near one end fixed cover of handle 3.In order to ensure to push core 1 outside
Pipe 2 is internal to be pushed smooth and ensures to push direction, the outside pushing core 1 is provided with spacing preiection 7, spacing preiection 7 is strip
Shape structure, spacing preiection 7 is near one end of jut 4 and axially arranged along push core 1, as shown in figure 4, in the present embodiment
Spacing preiection 7 be four, and along pushing the even circumferential setting of core 1, the inwall of the top of spacing preiection 7 and outer tube 2 slides
Cooperation, spacing preiection 7 plays to be prevented from pushing core 1 flexural deformation during pushing, and prevents from pushing core 1 in the mistake pushing simultaneously
There is jitter deviation in journey.
Outer tube 2 length of the present embodiment is 35cm-40cm, and internal diameter is 1.5mm-2mm, and push core 1 length is 35cm-
45cm, a diameter of 1mm-1.5mm, as long as ensure in practical application to push core 1 2mm longer than outer tube 2.
During concrete operations, pull out a part of distance from outer tube 2 pushing core 1, in order to ensure distance accurately, according to will move
Plant the quantity of ovary tissue section, to determine the suitable distance away from outer tube 2 end for the jut 4 pushing core 1, distance is by outer tube
Graduation mark on 2 tangent with jut 4 end determining, outer tube 2 can not be pulled out apart from excessive by pushing core 1, apart from excessive
Outer tube 2 end is easily made to enter excessive air, the quality of impact ovary tissue section, after determining the distance pushing core 1, ovum
Nest tissue slice (about 1.1-1.5mm) is put on the inner wall of end of outer tube 2 with micro-clipper, and about 20-30 block, then passes through every time
Laparoscopic surgery, the transplantation device that will be equipped with ovary tissue section puts transplantation site into, and pushing push core 1 makes tissue enter transplanting
Position, stops one second, pusher is taken out in then slow rotation.When so greatling save the transplanting that ovary tissue is cut into slices
Between, about 20 minutes, due to ovary tissue section, open-assembly time was short in vitro, was more beneficial for ovary tissue and postoperative patient fertility
The recovery of ability.
Above-described is only embodiments of the invention, and in scheme, the general knowledge here such as known concrete structure and characteristic is not made
Excessive description.It should be pointed out that for a person skilled in the art, on the premise of without departing from present configuration, acceptable
Make some deformation and improve, these also should be considered as protection scope of the present invention, these are implemented all without the impact present invention
Effect and practical applicability.This application claims protection domain should be defined by the content of its claim, in description
Specific embodiment etc. records the content that can be used for explaining claim.
Claims (10)
1. a kind of ovary tissue section pusher it is characterised in that: include pushing core and outer tube, outer coaxial tube is sheathed on push
The outside of core, the length pushing core is more than or equal to the length of outer tube, and the one end pushing core is fixedly connected with handle, pushes the another of core
One end is conformed with portion, and in outer tube, jut is slidably matched with the outer seal of tube for protruding part.
2. a kind of ovary tissue according to claim 1 cut into slices pusher it is characterised in that: the described outside pushing core
It is fixedly installed spacing preiection, spacing preiection is string configuration, and spacing preiection is along axially arranged, the spacing preiection pushing core
Multiple along the even circumferential setting pushing core, the top of spacing preiection is slidably matched with the inwall of outer tube.
3. a kind of ovary tissue section pusher according to claim 2 it is characterised in that: spacing preiection is near projection
Portion one end, and the length of spacing preiection is less than the length of outer tube.
4. according to a kind of arbitrary described ovary tissue section pusher of claim 1-3 it is characterised in that: described outer tube leans on
It is fixedly connected with spacing catch, the centre of spacing catch has spacing hole, pushes core from spacing hole at nearly handle one end open
Pass, spacing hole with diameter greater than push core diameter and less than lobe external diameter.
5. a kind of ovary tissue section pusher according to claim 1 it is characterised in that: outer tube is near the one of handle
End fixed cover is connected to grip part.
6. a kind of ovary tissue section pusher according to claim 1 it is characterised in that: the diameter of described handle is big
Diameter in outer tube.
7. a kind of ovary tissue section pusher according to claim 1 it is characterised in that: described jut is ellipse
Body structure.
8. a kind of ovary tissue section pusher according to claim 1 it is characterised in that: described outer tube is near projection
It is provided with graduation mark, graduation mark is axially arranged along outer tube at the position in portion.
9. a kind of ovary tissue section pusher according to claim 1 it is characterised in that: the outside of described handle sets
There is anti-skid bulge.
10. a kind of ovary tissue section pusher according to claim 1 it is characterised in that: the length of described outer tube
For 35cm-40cm, internal diameter is 1.5mm-2mm, and the length of described push core is 35cm-45cm, a diameter of 1mm-1.5mm, described
Push core than outer pipe range 2mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610768726.9A CN106344131B (en) | 2016-08-31 | 2016-08-31 | A kind of ovary tissue slice driving means |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610768726.9A CN106344131B (en) | 2016-08-31 | 2016-08-31 | A kind of ovary tissue slice driving means |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106344131A true CN106344131A (en) | 2017-01-25 |
| CN106344131B CN106344131B (en) | 2019-06-28 |
Family
ID=57856132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610768726.9A Active CN106344131B (en) | 2016-08-31 | 2016-08-31 | A kind of ovary tissue slice driving means |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106344131B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109330546A (en) * | 2018-11-12 | 2019-02-15 | 浙江大学 | Endoscope with wiping arrangement |
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| DE3613762A1 (en) * | 1986-04-23 | 1987-11-05 | Simmet Ludwig Dr Med Vet | Administration device for injectables, especially for instrumental insemination or transfer of embryos |
| CN2107247U (en) * | 1991-09-24 | 1992-06-17 | 刘兴 | Disposable two-purpose injector |
| CN2472675Y (en) * | 2001-04-20 | 2002-01-23 | 成都市计划生育技术指导所 | Simple embryo transplanter |
| CN2770676Y (en) * | 2004-06-07 | 2006-04-12 | 白登平 | Self-ruined disposable aseptic syringe |
| CN2790415Y (en) * | 2005-04-13 | 2006-06-28 | 阎沈军 | Filter type sperm separator |
| EP1721579A1 (en) * | 2005-05-10 | 2006-11-15 | Hans-Peter Steiner | Embryo transfer catheter |
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| CN201213834Y (en) * | 2008-07-07 | 2009-04-01 | 毕宜法 | Embryo transplantation tube |
| CN201643216U (en) * | 2010-05-10 | 2010-11-24 | 徐静 | Injector |
| GB2492986A (en) * | 2011-07-18 | 2013-01-23 | Shantal Rajah | Syringe with coarse and fine adjustment |
| CN103285464A (en) * | 2012-02-29 | 2013-09-11 | 王祖扬 | Needle head pull-back type needle-replaceable safe self-destruction syringe |
| CN204072169U (en) * | 2014-09-16 | 2015-01-07 | 北京大学深圳医院 | Endometrium harvester |
| US20160302828A1 (en) * | 2013-11-29 | 2016-10-20 | Smiths Medical International Limited | Syringe assemblies |
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2016
- 2016-08-31 CN CN201610768726.9A patent/CN106344131B/en active Active
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1080346B (en) * | 1959-03-24 | 1960-04-21 | Ehrenfried Zimmermann | Device for the artificial insemination of animals, especially cows |
| DE3613762A1 (en) * | 1986-04-23 | 1987-11-05 | Simmet Ludwig Dr Med Vet | Administration device for injectables, especially for instrumental insemination or transfer of embryos |
| CN2107247U (en) * | 1991-09-24 | 1992-06-17 | 刘兴 | Disposable two-purpose injector |
| CN2472675Y (en) * | 2001-04-20 | 2002-01-23 | 成都市计划生育技术指导所 | Simple embryo transplanter |
| CN2770676Y (en) * | 2004-06-07 | 2006-04-12 | 白登平 | Self-ruined disposable aseptic syringe |
| CN2790415Y (en) * | 2005-04-13 | 2006-06-28 | 阎沈军 | Filter type sperm separator |
| EP1721579A1 (en) * | 2005-05-10 | 2006-11-15 | Hans-Peter Steiner | Embryo transfer catheter |
| CN201157598Y (en) * | 2008-02-04 | 2008-12-03 | 王鑫磊 | Skid-proof injector |
| CN201213834Y (en) * | 2008-07-07 | 2009-04-01 | 毕宜法 | Embryo transplantation tube |
| CN201643216U (en) * | 2010-05-10 | 2010-11-24 | 徐静 | Injector |
| GB2492986A (en) * | 2011-07-18 | 2013-01-23 | Shantal Rajah | Syringe with coarse and fine adjustment |
| CN103285464A (en) * | 2012-02-29 | 2013-09-11 | 王祖扬 | Needle head pull-back type needle-replaceable safe self-destruction syringe |
| US20160302828A1 (en) * | 2013-11-29 | 2016-10-20 | Smiths Medical International Limited | Syringe assemblies |
| CN204072169U (en) * | 2014-09-16 | 2015-01-07 | 北京大学深圳医院 | Endometrium harvester |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109330546A (en) * | 2018-11-12 | 2019-02-15 | 浙江大学 | Endoscope with wiping arrangement |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106344131B (en) | 2019-06-28 |
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