CN203989192U - A kind of hemodialysis adsorber - Google Patents

A kind of hemodialysis adsorber Download PDF

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Publication number
CN203989192U
CN203989192U CN201420437079.XU CN201420437079U CN203989192U CN 203989192 U CN203989192 U CN 203989192U CN 201420437079 U CN201420437079 U CN 201420437079U CN 203989192 U CN203989192 U CN 203989192U
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China
Prior art keywords
hemodialysis
end cap
fiber layer
adsorber
chitin fiber
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CN201420437079.XU
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Chinese (zh)
Inventor
李曼
黄志贤
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GUANGZHOU QIJI BIOTECHNOLOGY CO., LTD.
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Steed Biotechnology (guangzhou) Co Ltd
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Abstract

The utility model discloses a kind of hemodialysis adsorber.It comprises housing, is provided with fibrous membrane pipe in housing, and the two ends of housing are connected with respectively tremulous pulse end cap and vein end cap, are provided with chitin fiber layer in vein end cap.Hemodialysis adsorber of the present utility model has increased chitin fiber layer in vein end cap, chitin fiber layer has that good virus killing is antibacterial, infection effect, purify blood and prevented antibacterial infection, there is good anticoagulant functions and biocompatibility simultaneously.

Description

A kind of hemodialysis adsorber
Technical field
This utility model relates to hemodialysis medical instruments field, relates in particular to a kind of hemodialysis adsorber.
Background technology
Hemodialysis is one of acute or chronic renal failure kidneys of patients Replacement Therapy.It is by being drained to external by body inner blood, through one by the dialyser forming without several hollow fibres in, blood to containing the similar electrolyte solution (dialysis solution) of body concentration inside and outside hollow fibre one by one, carry out mass exchange by disperse/convection current, remove metabolic waste in body, maintain electrolyte and acid-base balance; Remove too much moisture in body simultaneously.
Hemodialysis adsorber mainly utilizes the principle of semipermeable membrane, and patient's blood and dialysis solution are introduced to dialyser simultaneously, and both are in the both sides of dialyzer in the other direction flows, by solute gradient, osmotic gradient and the hydraulic pressure gradient of film both sides.Be detained too much moisture to reach to remove in toxin and body, simultaneously required material in added body.Dialyser is mainly made up of supporting construction and dialyzer, and wherein hollow fiber dialyzer is the class dialyser that current clinical use is maximum, effect is best.
Utility model content
For the deficiencies in the prior art, this utility model provides a kind of hemodialysis adsorber, this hemodialysis adsorber has increased chitin fiber layer in vein end cap, chitin fiber layer has that good virus killing is antibacterial, infection effect, purify blood and prevented antibacterial infection, there is good anticoagulant functions and biocompatibility simultaneously.
A kind of hemodialysis adsorber, comprises housing, is provided with fibrous membrane pipe in housing, and the two ends of housing are connected with respectively tremulous pulse end cap and vein end cap, are provided with chitin fiber layer in vein end cap, between chitin fiber layer and the outlet of vein end cap, is provided with filter course.
The macromolecular structure of chitin is identical with the formation of the glucosamine in human body, and there is the human bone of being similar to collagen tissue structure, this dual structure has been given their fabulous biomedical characteristics: it is nontoxic non-stimulated to human body, can be decomposed by the lysozyme in human body and absorb, have good biocompatibility with tissue, it has the functions such as antibacterial, antiinflammatory, hemostasis, analgesia, promotion wound healing.Chitin anti-infectious function, with chitin hexa polyose for the strongest.Micromolecular chitosan has protonated ammonium, the cell membrane effect that protonated ammonium and antibacterial are electronegative, and absorption and coagulation antibacterial, simultaneously penetration cell wall enters in cell, upsets the metabolism of antibacterial and synthesizes and have an antibacterial action.
Preferably, the sidewall of housing is provided with dialysis solution entrance and dialysis solution outlet, and the end of dialysis solution entrance is provided with reclinate drainage plate.
Preferably, the internal diameter of fibrous membrane pipe is 150~165 μ m, and the wall thickness of fibrous membrane pipe is 25~30 μ m.For example fibrous membrane bore can be 150 μ m, 155 μ m, 160 μ m, 165 μ m, and the wall thickness of fibrous membrane pipe can be 25 μ m, 26 μ m, 27 μ m, 28 μ m, 29 μ m, 30 μ m.
Preferably, chitin fiber layer thickness is 50~300 μ m, and filter course thickness is 10~50 μ m.For example chitin fiber layer thickness can be 50 μ m, 100 μ m, 150 μ m, 200 μ m, 250 μ m, 300 μ m, and filter course thickness can be 10 μ m, 20 μ m, 30 μ m, 40 μ m, 50 μ m.
Compared with prior art, the utlity model has following beneficial effect: the hemodialysis adsorber that this utility model provides comprises housing, in housing, be provided with fibrous membrane pipe, the two ends of housing are connected with respectively tremulous pulse end cap and vein end cap, are provided with chitin fiber layer in vein end cap.Hemodialysis adsorber of the present utility model has increased chitin fiber layer in vein end cap, chitin fiber layer has that good virus killing is antibacterial, infection effect, purify blood and prevented antibacterial infection, there is good anticoagulant functions and biocompatibility simultaneously.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model.
Accompanying drawing indicates as follows: 1-housing, 2-tremulous pulse end cap, 3-vein end cap, 11-fibrous membrane pipe, 12-dialysis solution entrance, 13-drainage plate, the outlet of 14-dialysis solution, 31-chitin fiber layer, 32-filter course.
Detailed description of the invention
Below in conjunction with accompanying drawing, this utility model is described in detail.
Referring to Fig. 1, a kind of hemodialysis adsorber of the present embodiment, a kind of hemodialysis adsorber, comprise housing 1, in housing 1, be provided with fibrous membrane pipe 11, the two ends of housing 1 are connected with respectively tremulous pulse end cap 2 and vein end cap 3, are provided with chitin fiber layer 31 in vein end cap 3, between chitin fiber layer 31 and 3 outlets of vein end cap, are provided with filter course 32.Hemodialysis adsorber of the present utility model is at interior chitin fiber layer 31 and the filter course 32 of having increased of vein end cap 3, chitin fiber layer 31 has that good virus killing is antibacterial, infection effect, purify blood and prevented antibacterial infection, there is good anticoagulant functions and biocompatibility simultaneously, filter course 32 further filters impurity, metabolite in blood, guarantees to flow into that blood in human body is clean, free from admixture.
Preferably, the sidewall of housing 1 is provided with dialysis solution entrance 12 and dialysis solution outlet 14, and the end of dialysis solution entrance 12 is provided with reclinate drainage plate 13.Housing 1 internal cavities forms dialysis chamber, drainage plate 13 changes dialysis solution and enters the direction of dialysis chamber, avoid the impact of dialysis solution to fibrous membrane pipe 11, drainage plate 13 is bent downwardly, make dialysis solution be introduced into dialysis chamber bottom, upruss again, has accelerated particularly dialysis chamber bottom dialysis solution circulation in dialysis chamber, has changed, and has improved dialytic efficiency.
Preferably, the internal diameter of fibrous membrane pipe 11 is 150~165 μ m, and wall thickness is 25~30 μ m.In the present embodiment, adopt than the internal diameter of common dialyzer Guan Geng little and wall thickness, therefore under same film area, can obtain little blood volume, in dialysis procedure, there is less transmembrane pressure, therefore material is shorter in the distance that sees through fiber membranous wall in dialysis procedure, removing material is more prone to, and has improved the dialysis-effect of hemodialysis membrane.
Preferably, chitin fiber layer 31 thickness are 50~300 μ m, and filter course 32 thickness are 10~50 μ m.Ensured that kill virus antibacterial, infection, anticoagulant effect of chitin fiber layer 31 do not affect again the flow of blood.
Work process of the present utility model: dialysis solution is accessed to dialysis solution entrance 12, the entrance of blood samples of patients access tremulous pulse end cap 2, blood and the dialysis solution opposite direction that flows, the metabolite of putting aside in blood and too much water utilization fibrous membrane pipe 11 are discharged in dialysis solution, dialysis solution supplements base to correct acidosis, to adjust electrolyte wadding disorderly by fibrous membrane pipe 11 in blood, blood after dialysis is through chitin fiber layer 31 and filter course 32, finally flowed out and entered human body by the outlet of vein end cap 3, the dialysis solution that contains metabolite exports 14 by dialysis solution and discharges.
Applicant's statement, this utility model illustrates detailed structure of the present utility model and technique by above-described embodiment, but this utility model is not limited to above-mentioned detailed structure and technique, do not mean that this utility model must rely on above-mentioned detailed structure and technique could be implemented.Person of ordinary skill in the field should be understood that; to any improvement of the present utility model; the selections of the equivalence replacement to the each raw material of this utility model product and the interpolation of auxiliary element, concrete mode etc., within all dropping on protection domain of the present utility model and open scope.

Claims (6)

1. a hemodialysis adsorber, it is characterized in that, comprise housing (1), in described housing (1), be provided with fibrous membrane pipe (11), the two ends of described housing (1) are connected with respectively tremulous pulse end cap (2) and vein end cap (3), are provided with chitin fiber layer (31) in described vein end cap (3).
2. hemodialysis adsorber according to claim 1, is characterized in that, between described chitin fiber layer (31) and the outlet of described vein end cap (3), is provided with filter course (32).
3. hemodialysis adsorber according to claim 1, it is characterized in that, the sidewall of described housing (1) is provided with dialysis solution entrance (12) and dialysis solution outlet (14), and the end of described dialysis solution entrance (12) is provided with reclinate drainage plate (13).
4. hemodialysis adsorber according to claim 3, is characterized in that, the internal diameter of described fibrous membrane pipe (11) is 150~165 μ m, and wall thickness is 25~30 μ m.
5. hemodialysis adsorber according to claim 1, is characterized in that, described chitin fiber layer (31) thickness is 50~300 μ m.
6. hemodialysis adsorber according to claim 1, is characterized in that, described filter course (32) thickness is 10~50 μ m.
CN201420437079.XU 2014-08-04 2014-08-04 A kind of hemodialysis adsorber Active CN203989192U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420437079.XU CN203989192U (en) 2014-08-04 2014-08-04 A kind of hemodialysis adsorber

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Application Number Priority Date Filing Date Title
CN201420437079.XU CN203989192U (en) 2014-08-04 2014-08-04 A kind of hemodialysis adsorber

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105771014A (en) * 2016-03-29 2016-07-20 艾沃生物科技(苏州)有限公司 Plasma filter capable of adsorbing OFR (oxygen free radical)
CN108114334A (en) * 2016-11-28 2018-06-05 珠海健帆生物科技股份有限公司 Blood purification, blood purification system and its pre- punching method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105771014A (en) * 2016-03-29 2016-07-20 艾沃生物科技(苏州)有限公司 Plasma filter capable of adsorbing OFR (oxygen free radical)
CN108114334A (en) * 2016-11-28 2018-06-05 珠海健帆生物科技股份有限公司 Blood purification, blood purification system and its pre- punching method
CN108114334B (en) * 2016-11-28 2024-01-12 健帆生物科技集团股份有限公司 Blood purifier, blood purifying system and pre-flushing method thereof

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Address after: 510000, 33, science Avenue, Science Town, Guangzhou hi tech Industrial Development Zone, Guangdong, five, 201, 209 rooms

Patentee after: GUANGZHOU QIJI BIOTECHNOLOGY CO., LTD.

Address before: 510000 nine, 333 Jianshe Road, Guangzhou, Guangdong, Guangzhou, China

Patentee before: Steed Biotechnology (Guangzhou) Co., Ltd.