CN203694203U - Electrode separation type dialysis device for treating heavy metal poisoning - Google Patents
Electrode separation type dialysis device for treating heavy metal poisoning Download PDFInfo
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- CN203694203U CN203694203U CN201420021137.0U CN201420021137U CN203694203U CN 203694203 U CN203694203 U CN 203694203U CN 201420021137 U CN201420021137 U CN 201420021137U CN 203694203 U CN203694203 U CN 203694203U
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- dialysis
- heavy metal
- blood
- dialyzer
- electrochemistry
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Abstract
The utility model mainly relates to an electrode separation type dialysis device for treating heavy metal positioning. The device comprises a pulsation pump I, an electrochemistry dialysis column, an ultra-filtration dialyzer, a bubble valve and a pulsation pump II. The electrochemistry dialysis column is partitioned into an anode chamber, a cathode chamber and a blood channel by a positive ion dialysis membrane and a negative ion dialysis membrane, wherein the top end of the anode chamber and the top end of the cathode chamber are communicated with an anode dialysis liquid groove and a cathode dialysis liquid groove respectively, and the two ends of the blood channel are communicated with the pulsation pump I and the ultra-filtration dialyzer respectively. The ultra-filtration dialyzer is partitioned into a dialysis liquid chamber and a blood chamber by an ultra-filtration membrane. A complex generated by heavy metal ions and serum protein in heavy metal poisoning blood is directly dissociated through a static electric field so that the heavy metal ions can be separated from the complex, gather towards the cathode under the action of static electric field force and become heavy metal through the reduction reaction, the heavy metal is deposited to an electrode plate, and the purposes of purifying blood and treating heavy metal poisoning are achieved.
Description
Technical field
this utility model belongs to the medical instruments field for the treatment of heavy metal poisoning, is specifically related to a kind of electrode separation formula dialysis apparatus for the treatment of heavy metal poisoning.
Background technology
The primary treatment method of existing heavy metal poisoning disease is mainly Drug therapy, and its principle is that patient passes through drug administration metal chelating agent, becomes nontoxic complex to excrete by urine with heavy metal of body complexation.The defect of this Therapeutic Method is: 1. metal chelating agent has toxic and side effects; 2. add the load of double kidney and cause even renal failure of injury of kidney, have the uremic danger of formation; 3. treatment cycle length and treatment are not thorough.What is more important is also of no curative effect now, comparatively ripe excretion medicine.
The treatment of heavy metal poisoning disease also has plasmapheresis (Plasma exchange, PE method), plasmapheresis is that the morbid substance in human body or toxin are discarded or by abnormal separating plasma from separating plasma, remove antigen or antibody wherein through immunoadsorption or cooling filtration, more a kind of technology that adds displacement liquid to feed back remaining blood formed element.The main defect of this Therapeutic Method is that blood plasma consumption is large, and expense is too expensive, is difficult for universal.
Another Therapeutic Method of blood purification is blood dialysis (Hemodialysis, HD), i.e. artificial kidney treatment technology.But existing artificial kidney dialysis's equipment is by its biophysical mechanism, complete removing and transhipment to solute and water, its ultimate principle is to remove various endogenouss and exogenous " toxin " in blood by disperse (Diffusion), convection current (Convection) and absorption (Absorption); Remove moisture and the micromolecule toxin of retention in body by ultrafiltration (Ultrafiltration) and infiltration (Osmosis), correct electrolyte and acid base imbalance simultaneously, thereby make organismic internal environment approach the object that normally reaches treatment.Because the heavy metal poisons such as lead, cadmium, chromium, copper, cobalt, magnesium, hydrargyrum, bismuth are the macro-radicals to exist with protein complex form, existing artificial kidney dialysis's equipment can not be by external metal species toxic removal, so can not be used for the treatment of heavy metal poisoning disease.
Utility model content
The purpose of this utility model is for problems of the prior art, a kind of electrode separation formula dialysis apparatus for the treatment of heavy metal poisoning is provided, this device utilizes the electrostatic field force complex that heavy metal ion and serum albumin generate in heavy metal poisoning blood that directly dissociates, heavy metal ion is separated from complex, and assemble to negative electrode under the effect of electrostatic field force, be reduced into heavy metal deposition on battery lead plate, finally reach therefrom separating beavy metal in toxenia liquid, treatment heavy metal poisoning disease object purifies the blood.
The technical scheme that this utility model is realized above-mentioned purpose employing is: a kind of electrode separation formula dialysis apparatus for the treatment of heavy metal poisoning, described device comprises the jerk pump I, electrochemistry dialysis cartridge, ultrafiltration dialysis device, bubble valve and the jerk pump II that connect successively, jerk pump I is connected with the blood drawing pipeline for being connected human body artery blood vessel, and jerk pump II is connected with the Blood transfusion tubeline for being connected human vein blood vessel;
Described electrochemistry dialysis cartridge is separated into three compartments by cation dialyzer and anion dialyzer, be respectively cathode chamber between anode chamber, anion dialyzer and the electrochemistry dialysis cartridge inwall between cation dialyzer and electrochemistry dialysis cartridge inwall and the blood channel between cation dialyzer and anion dialyzer, the top of anode chamber and cathode chamber is communicated with respectively anode dialysis liquid bath and negative electrode dialysis liquid bath, its bottom is all communicated with waste liquid cylinder, and the two ends of blood channel are communicated with jerk pump I and ultrafiltration dialysis device respectively;
Described ultrafiltration dialysis device is separated into dialysis fluid chamber and two of hematology labs compartment by ultrafilter membrane, and hematology lab is communicated with electrochemistry dialysis cartridge and bubble valve, and the top of dialysis fluid chamber and bottom are respectively equipped with ultrafiltration dialysis liquid bath and waste liquid cylinder.
Between described jerk pump I and blood drawing pipeline for being connected human body artery blood vessel, be provided with heparin pump and carbon filter I, heparin pump is connected with blood drawing pipeline.
Between described ultrafiltration dialysis device and bubble valve, be provided with carbon filter II.
The beneficial effects of the utility model
(1) the electrode separation formula dialysis apparatus that this utility model provides utilizes the electrostatic field force complex that heavy metal ion and serum albumin generate in heavy metal poisoning blood that directly dissociates, heavy metal ion is separated from complex, and assemble to negative electrode under the effect of electrostatic field force, be reduced into heavy metal deposition on battery lead plate, finally reach therefrom separating beavy metal in toxenia liquid, purify the blood, treat heavy metal poisoning disease object.
(2) this utility model is serially connected with ultrafiltration dialysis device after electrochemistry is dialysed, and is beneficial to the heavy metal ion in free state in blood to separate from blood, improves the dialysis-effect of device.
(3) core of the present utility model adopts electrode separation formula, and blood flows through from the blood channel in the middle of electrolysis bath, does not directly contact with electrode, avoided blood directly contact with electrode the issuable impact on its activity.
(4) adopt device dialysis that this utility model provides 10-14 hour can be by blood lead concentration the blood lead concentration of the severe intoxication patient more than the 600 μ g/ moderate intoxication state below 300 μ g/L, the condition of illness of reduction of patient greatly.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model;
Reference numeral: 1, jerk pump I, 2, electrochemistry dialysis cartridge, 201, cation dialyzer, 202, anion dialyzer, 203, anode chamber, 204, blood channel, 205, cathode chamber, 206, anode dialysis liquid bath, 207, negative electrode dialysis liquid bath, 208, waste liquid cylinder, 3, ultrafiltration dialysis device, 301, dialysis fluid chamber, 302, hematology lab, 303, ultrafiltration dialysis liquid bath, 4, bubble valve, 5, jerk pump II, 6, heparin pump.
The specific embodiment
By reference to the accompanying drawings this utility model is further explained to explanation: a kind of electrode separation formula dialysis apparatus for the treatment of heavy metal poisoning, described device comprises the jerk pump I 1, electrochemistry dialysis cartridge 2, ultrafiltration dialysis device 3, bubble valve 4 and the jerk pump II 5 that connect successively, between described jerk pump I 1 and blood drawing pipeline for being connected human body artery blood vessel, be provided with heparin pump 6 and carbon filter I, heparin pump 6 is connected with blood drawing pipeline, and jerk pump II 5 is connected with the Blood transfusion tubeline for being connected human vein blood vessel;
Described electrochemistry dialysis cartridge 2 is separated into three compartments by cation dialyzer 201 and anion dialyzer 202, be respectively the anode chamber 203 between cation dialyzer 201 and electrochemistry dialysis cartridge 2 inwalls, cathode chamber 205 between anion dialyzer 202 and electrochemistry dialysis cartridge 2 inwalls, and blood channel 204 between cation dialyzer 201 and anion dialyzer 202, the top of anode chamber 203 and cathode chamber 205 is communicated with respectively anode dialysis liquid bath 206 and negative electrode dialysis liquid bath 207, its bottom is all communicated with waste liquid cylinder 208, the two ends of blood channel 204 are communicated with jerk pump I 1 and ultrafiltration dialysis device 3 respectively, between ultrafiltration dialysis device 3 and bubble valve 4, be provided with carbon filter II,
Described ultrafiltration dialysis device 3 is separated into dialysis fluid chamber 301 and 302 two of hematology labs compartment by ultrafilter membrane, and hematology lab 302 is communicated with electrochemistry dialysis cartridge 2 and bubble valve 4, and the top of dialysis fluid chamber 301 and bottom are respectively equipped with ultrafiltration dialysis liquid bath 303 and waste liquid cylinder 208.
The device treatment heavy metal poisoning that adopts this utility model to provide; can omit renal excretion link; accelerate on the one hand drainage rate; alleviate on the other hand the load of renal excretion heavy metal; be conducive to prevent from being subject to the patient of the poisoning harm of heavy metal poison such as lead, cadmium, chromium to occur that renal function damages, thereby play the effect of effective protection kidney.Analog reslt proves that this device is feasible.
The electrode separation formula dialysis apparatus that this utility model provides can utilize the electrostatic field force complex that heavy metal ion and serum albumin generate in heavy metal poisoning blood that directly dissociates, heavy metal ion is separated from complex, and assemble to negative electrode under the effect of electrostatic field force, be reduced into heavy metal deposition on battery lead plate, finally reach therefrom separating beavy metal in toxenia liquid, treatment heavy metal poisoning disease object purifies the blood.
This utility model is serially connected with ultrafiltration dialysis device 3 after electrochemistry is dialysed, and is beneficial to the heavy metal ion in free state in blood to separate from blood, improves the dialysis-effect of device.
Core of the present utility model adopts electrode separation formula, and blood flows through from the blood channel 204 in the middle of electrolysis bath, does not directly contact with electrode, avoided blood directly contact with electrode the issuable impact on its activity.
Adopt device dialysis that this utility model provides 10-14 hour can be by blood lead concentration the blood lead concentration of the severe intoxication patient more than the 600 μ g/ moderate intoxication state below 300 μ g/L, the condition of illness of reduction of patient greatly.
Claims (3)
1. treat the electrode separation formula dialysis apparatus of heavy metal poisoning for one kind, it is characterized in that: described device comprises the jerk pump I (1), electrochemistry dialysis cartridge (2), ultrafiltration dialysis device (3), bubble valve (4) and the jerk pump II (5) that connect successively, jerk pump I (1) is connected with the blood drawing pipeline for being connected human body artery blood vessel, and jerk pump II (5) is connected with the Blood transfusion tubeline for being connected human vein blood vessel;
Described electrochemistry dialysis cartridge (2) is separated into three compartments by cation dialyzer (201) and anion dialyzer (202), be respectively the anode chamber (203) between cation dialyzer (201) and electrochemistry dialysis cartridge (2) inwall, cathode chamber (205) between anion dialyzer (202) and electrochemistry dialysis cartridge (2) inwall, and blood channel (204) between cation dialyzer (201) and anion dialyzer (202), the top of anode chamber (203) and cathode chamber (205) is communicated with respectively anode dialysis liquid bath (206) and negative electrode dialysis liquid bath (207), its bottom is all communicated with waste liquid cylinder (208), the two ends of blood channel (204) are communicated with jerk pump I (1) and ultrafiltration dialysis device (3) respectively,
Described ultrafiltration dialysis device (3) is separated into dialysis fluid chamber (301) and (302) two of hematology labs compartment by ultrafilter membrane, hematology lab (302) is communicated with electrochemistry dialysis cartridge (2) and bubble valve (4), and the top of dialysis fluid chamber (301) and bottom are respectively equipped with ultrafiltration dialysis liquid bath (303) and waste liquid cylinder (208).
2. a kind of electrode separation formula dialysis apparatus for the treatment of heavy metal poisoning as claimed in claim 1, it is characterized in that: between described jerk pump I (1) and blood drawing pipeline for being connected human body artery blood vessel, be provided with heparin pump (6) and carbon filter I, heparin pump (6) is connected with blood drawing pipeline.
3. a kind of electrode separation formula dialysis apparatus for the treatment of heavy metal poisoning as claimed in claim 1, is characterized in that: between described ultrafiltration dialysis device (3) and bubble valve (4), be provided with carbon filter II.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420021137.0U CN203694203U (en) | 2014-01-14 | 2014-01-14 | Electrode separation type dialysis device for treating heavy metal poisoning |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420021137.0U CN203694203U (en) | 2014-01-14 | 2014-01-14 | Electrode separation type dialysis device for treating heavy metal poisoning |
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| Publication Number | Publication Date |
|---|---|
| CN203694203U true CN203694203U (en) | 2014-07-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420021137.0U Expired - Fee Related CN203694203U (en) | 2014-01-14 | 2014-01-14 | Electrode separation type dialysis device for treating heavy metal poisoning |
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| CN (1) | CN203694203U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751868A (en) * | 2014-01-14 | 2014-04-30 | 河南科技大学 | Electrode separating typed dialyze device for treating heavy metal poisoning |
-
2014
- 2014-01-14 CN CN201420021137.0U patent/CN203694203U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751868A (en) * | 2014-01-14 | 2014-04-30 | 河南科技大学 | Electrode separating typed dialyze device for treating heavy metal poisoning |
| CN103751868B (en) * | 2014-01-14 | 2016-05-11 | 河南科技大学 | A kind of electrode separation formula dialysis apparatus for the treatment of heavy metal poisoning |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140709 Termination date: 20150114 |
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| EXPY | Termination of patent right or utility model |