CN203988366U - A kind of for the online device detecting of artificial organ surface blood coagulation - Google Patents
A kind of for the online device detecting of artificial organ surface blood coagulation Download PDFInfo
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- CN203988366U CN203988366U CN201420228507.8U CN201420228507U CN203988366U CN 203988366 U CN203988366 U CN 203988366U CN 201420228507 U CN201420228507 U CN 201420228507U CN 203988366 U CN203988366 U CN 203988366U
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- optical sensor
- blood coagulation
- fibre optical
- blood
- artificial organ
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Abstract
The utility model discloses a kind of for the online device detecting of artificial organ surface blood coagulation, by Fibre Optical Sensor is set on artificial organ, luminous source optical fiber emits beam and injects clear coat, and in the time there is no blood, light receives at the inner also received optical fiber of total reflection that occurs of anticoagulant coatings; In the time having blood flow to cross anticoagulant coatings surface, blood forms liquid film and covers anticoagulant coatings surface, and part refraction can occur light, and the light that reception optical fiber receives can weaken, judge blood coagulation situation according to receiving the strong and weak of signal and whether stablizing, judgement early and detection blood coagulation.By Fibre Optical Sensor being fixed on below anticoagulant coatings, anticoagulant coatings can effectively be protected Fibre Optical Sensor, ensures high reliability and the service life of Fibre Optical Sensor.Adopt the mode of array to be uniformly distributed in the surface of artificial organ Fibre Optical Sensor, can judge more accurately the position of concrete blood coagulation, a situation arises better to judge blood coagulation, promptly and accurately give doctor's feedback information.
Description
Technical field
This utility model belongs to medical checkout equipment technical field, is specifically related to a kind of for the online device detecting of artificial organ surface blood coagulation.
Background technology
Artificial organ is the Prosthesis who temporarily or permanently replaces some organ major function of health.Use and have more widely: 1. artificial lung (oxygenator) test lung is carried out the device of O2 and CO2 exchange, makes body include the venous oxygen that oxygen is low be combined into the arterial blood high containing oxygen by oxygenator.2. artificial heart (blood pump).The device that replaces cardiac ejection function, structure is similar to pump, can drive blood flow to overcome resistance along one-way flow.Artificial heart and artificial lung are collectively referred to as heart-lung machine, in nineteen fifty-three first for human body, are mainly applicable to complicated operation on heart.3. artificial kidney (hemodialyzer).Artificial organ has a wide range of applications in medical science, is significant for the treatment of suffering from the afunction of various tissues, organ or the patient of dysfunction disease.Widen the approach of disease treatment, increased the chance that patient is rescued, and still continued that increasing patient is benefited.
In artificial organ, taking artificial heart as example, also have biocompatibility issues with tissue, blood etc., wherein artificial organ surface contacts the blood coagulation problem causing with blood, and artificial organ and human body are all existed to very large harm.Blood coagulation is the chemical chain reaction process of series of complex, has the mechanism that maintains blood proper flow in human body, neither hemorrhage, also can not cause thrombosis.But, when body whole body or local blood coagulation system are strengthened or anticoagulation system weakens, fibrinolytic (thrombolytic) ability declines or anti-fibrinolytic strengthens, for example, under the effect of some inducement (having the existence of artificial organ), just may cause the thrombosis of thrombosis or formation can not be cleared out external, blood is ubiquitous, and thrombosis or thromboembolism can occur in any position of health, causes that vascular flow obviously reduces one group of disease of interrupting even completely.If thrombosis occurs in tremulous pulse, can cause organ or tissue's severe ischemic of blood supply or blood flow to interrupt, as cerebral blood supply insufficiency, unstable angina pectoris; Also can cause organ or tissue because of ischemia necrosis, as acute myocardial infarction, apoplexy.If thrombosis occurs in vein, as deep venous thrombosis of lower limbs can cause lower limb blood backflow obstacle, cause edema and impaired function of vein etc.
Thromboembolism is established thrombosis in heart or blood vessel, and after coming off, antegrade blood flow stops up the syndrome of other important organ blood vessels.As patients with atrial fibrillation often has thrombosis in left atrium.Once thrombosis comes off, can get lodged in cerebrovascular by antegrade blood flow, cause cerebral tissue necrosis (cerebral embolism); Deep vein thrombosis of lower extremity comes off, and can stop up pulmonary artery (pulmonary infarction), causes acute right heart failure, serious caused death.
If the disease that some are caused by blood coagulation or thrombosis is controlled at pathogenetic " upstream " stage of disease, judgement early and detection blood coagulation, the meaning of preventing for these major diseases is so by self-evident.
After material is as foreign body implant into body, cause such as thrombosis, inflammation, toxic reaction and many bad reactions such as carcinogenic.Wherein in the time that implant contacts with blood, by protedogenous product absorption and hematoblastic sticking.It is generally acknowledged, after embedded material contacts with blood, its protein and lipid are adsorbed on material surface, because the conformation of these molecules changes, cause each composition in blood to interact, thereby bring out the intrinsic coagulation reaction with thrombin activation; Then there is the cell component such as platelet, erythrocyte and be attached to protein surface, the platelet generation degeneration that those are sticked will discharge the III factor and impels the activation of blood coagulation system, generation blood coagulation reaction, and then form thrombosis, the formation of Intravascular Thrombus also can cause fatal consequence.Therefore, the bio-medical material of artificial blood vessel, artificial heart haematodocha, prosthetic heart valve film, artificial lung etc. not only will have the elasticity similar to human vas and ductility and good fatigue durability etc., more to there is good anticoagulant property antibacterium adhesion, do not produce thrombosis at material surface, do not cause platelet, the infection centered by biomaterial does not occur.
Artificial organ and blood contacting surface mainly adopt the material with anticoagulant property to process or apply on surface at present, manufacturing cost and the difficulty of organ are not only increased, but also can not play anticoagulant function completely, once generation blood coagulation, only have to just reflecting by clinical manifestation when more serious, often patient is caused to great misery and serious consequence.
Therefore, in view of above problem, be necessary to propose a kind of Hemostasis examination device, can judge more accurately the position of concrete blood coagulation, a situation arises better judge blood coagulation, promptly and accurately to doctor's feedback information, the disease that blood coagulation or thrombosis can be caused is controlled at pathogenetic " upstream " stage of disease, judgement early and detection blood coagulation, guarantee patient's health.
Utility model content
In view of this, it is a kind of for the online device detecting of artificial organ surface blood coagulation that this utility model provides, by Fibre Optical Sensor is set, according to the strong and weak of light signal fed back and whether stablize and can better judge blood coagulation a situation arises, the accurate position that judge concrete blood coagulation, promptly and accurately to doctor's feedback information, the disease that blood coagulation or thrombosis can be caused is controlled at pathogenetic " upstream " stage of disease, judgement early and detection blood coagulation, guarantee patient's health.
What propose according to the purpose of this utility model is a kind of for the online device detecting of artificial organ surface blood coagulation, this device comprises Fibre Optical Sensor, described Fibre Optical Sensor is fixed on the surface of described artificial organ, the outside of described Fibre Optical Sensor is coated with one deck anticoagulant coatings, and described Fibre Optical Sensor is equally distributed multiple;
Described Fibre Optical Sensor comprises luminous source optical fiber and reception optical fiber, and described anticoagulant coatings is clear coat.
Preferably, described Fibre Optical Sensor is array format distribution.
Compared with prior art, the disclosed advantage for the online device detecting of artificial organ surface blood coagulation of this utility model is:
1, by Fibre Optical Sensor is set on artificial organ, luminous source optical fiber emits beam and injects clear coat, and in the time there is no blood, light receives at the inner also received optical fiber of total reflection that occurs of anticoagulant coatings; In the time having blood flow to cross anticoagulant coatings surface, blood forms liquid film and covers anticoagulant coatings surface, and part refraction can occur light, and the light that reception optical fiber receives can weaken, judge blood coagulation situation according to receiving the strong and weak of signal and whether stablizing, judgement early and detection blood coagulation.
2, by Fibre Optical Sensor being fixed on below anticoagulant coatings, anticoagulant coatings can effectively be protected Fibre Optical Sensor, ensures high reliability and the service life of Fibre Optical Sensor.
3, Fibre Optical Sensor is adopted the mode of array be uniformly distributed in the surface of artificial organ, can judge more accurately the position of concrete blood coagulation, a situation arises better to judge blood coagulation, promptly and accurately give doctor's feedback information.
Brief description of the drawings
In order to be illustrated more clearly in this utility model embodiment or technical scheme of the prior art, to the accompanying drawing of required use in embodiment or description of the Prior Art be briefly described below, apparently, accompanying drawing in the following describes is only embodiment more of the present utility model, for those of ordinary skill in the art, do not paying under the prerequisite of creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 is the disclosed a kind of structural representation for the online device detecting of artificial organ surface blood coagulation of this utility model.
Fig. 2 is not for there is no the out-of-date a of blood flow place's light incident figure.
Light incident figure in a place when Fig. 3 is blood coagulation.
Fig. 4 is the local scattergram that amplifies of Fibre Optical Sensor.
The title of the numeral in figure or the corresponding component of alphabetical representative:
1, artificial organ 2, anticoagulant coatings 3, Fibre Optical Sensor 4, sludged blood
A, luminous source optical fiber B, reception optical fiber
Detailed description of the invention
Artificial organ and blood contacting surface mainly adopt the material with anticoagulant property to process or apply on surface at present, manufacturing cost and the difficulty of organ are not only increased, but also can not play anticoagulant function completely, once generation blood coagulation, only have to just reflecting by clinical manifestation when more serious, often patient is caused to great misery and serious consequence.
This utility model is for deficiency of the prior art, provide a kind of for the online device detecting of artificial organ surface blood coagulation, by Fibre Optical Sensor is set, according to the strong and weak of optical signal and whether stablize and can better judge blood coagulation a situation arises, the accurate position that judge concrete blood coagulation, promptly and accurately to doctor's feedback information, the disease that blood coagulation or thrombosis can be caused is controlled at pathogenetic " upstream " stage of disease, judgement early and detection blood coagulation, guarantee patient's health.
To be clearly and completely described the technical solution of the utility model by detailed description of the invention below.Obviously, described embodiment is only this utility model part embodiment, instead of whole embodiment.Based on the embodiment in this utility model, those of ordinary skill in the art are not making the every other embodiment obtaining under creative work prerequisite, all belong to the scope of this utility model protection.
As shown in Figure 1, for the online device detecting of artificial organ surface blood coagulation, this device comprises Fibre Optical Sensor 3, and Fibre Optical Sensor 3 is fixed on the surface of artificial organ 1, the outside of Fibre Optical Sensor 3 is coated with one deck anticoagulant coatings 2, and Fibre Optical Sensor 3 is equally distributed multiple.
Fibre Optical Sensor 3 comprises luminous source optical fiber A and reception optical fiber B, and anticoagulant coatings is clear coat.Form sensing system by adopting clear coat to coordinate with Fibre Optical Sensor, realize the object that detects blood coagulation by reflection ray.Concrete principle is as follows:
As shown in Figure 2,3, luminous source optical fiber emits beam and injects clear coat, and in the time there is no blood, light receives at the inner also received optical fiber of total reflection that occurs of clear coat; In the time having blood flow to cross clear coat surface, blood formation liquid film covers the surface of clear coat, and part refraction can occur light, and the light that reception optical fiber receives can weaken, but the signal receiving is a more stable value; In the time having blood coagulation to occur, the absorption difference of thrombin to light, can not change incident light wavelength, and obvious variation can occur the light intensity receiving, thereby judges the situation that blood coagulation occurs, and feeds back to timely doctor and carries out diagnosis in early stage.
Wherein, anticoagulant coatings can be diamond coatings, and diamond coatings is good anticoagulant material, realizes anticoagulation characteristic, avoid blood to produce blood coagulation phenomenon on its surface, but also other anticoagulant materials of anticoagulant coatings does not specifically limit.
In addition, cover completely Fibre Optical Sensor by anticoagulant coatings is set, avoided Fibre Optical Sensor to contact with the direct of blood, effectively protect Fibre Optical Sensor, ensure high reliability and the long service life of Fibre Optical Sensor.
As shown in Figure 4, Fibre Optical Sensor is array format and distributes, and can judge more accurately the position of concrete blood coagulation, and a situation arises better to judge blood coagulation, promptly and accurately give doctor's feedback information.
Artificial organ adopts the materials processing with anticoagulant property.
Artificial organ surface Hemostasis examination method, concrete steps are as follows:
(1), machine-shaping artificial organ, and be fixedly installed Fibre Optical Sensor on the surface of artificial organ, and Fibre Optical Sensor is array distribution;
(2), apply a side anticoagulant coatings in the outside of Fibre Optical Sensor, cover Fibre Optical Sensor completely, and anticoagulant coatings is clear coat, between Fibre Optical Sensor and this clear coat, form sensing system;
(3), artificial organ is applied in human body, luminous source optical fiber emits beam and injects clear coat, and in the time there is no blood, light total reflection occurs and received optical fiber receives clear coat is inner; In the time having blood flow to cross clear coat surface, blood formation liquid film covers the surface of clear coat, and part refraction can occur light, and the light that reception optical fiber receives can weaken, but the signal receiving is a more stable value; In the time having blood coagulation to occur, the absorption difference of different thrombins to light, can change incident light wavelength, and obvious variation can occur the light intensity receiving, thereby judges the situation that blood coagulation occurs;
(4), will receive signal feedback output, offer doctor and carry out judgement in early stage and diagnosis and treatment, the mode of Fibre Optical Sensor employing array, can accurately judge the particular location of artificial organ blood coagulation.
The utility model discloses a kind of for the online device detecting of artificial organ surface blood coagulation, by Fibre Optical Sensor is set on artificial organ, luminous source optical fiber emits beam and injects clear coat, and in the time there is no blood, light receives at the inner also received optical fiber of total reflection that occurs of anticoagulant coatings; In the time having blood flow to cross anticoagulant coatings surface, blood forms liquid film and covers anticoagulant coatings surface, and part refraction can occur light, and the light that reception optical fiber receives can weaken, judge blood coagulation situation according to receiving the strong and weak of signal and whether stablizing, judgement early and detection blood coagulation.
By Fibre Optical Sensor being fixed on below anticoagulant coatings, anticoagulant coatings can effectively be protected Fibre Optical Sensor, ensures high reliability and the service life of Fibre Optical Sensor.
Adopt the mode of array to be uniformly distributed in the surface of artificial organ Fibre Optical Sensor, can judge more accurately the position of concrete blood coagulation, a situation arises better to judge blood coagulation, promptly and accurately give doctor's feedback information.
To the above-mentioned explanation of the disclosed embodiments, make professional and technical personnel in the field can realize or use this utility model.To be apparent for those skilled in the art to the multiple amendment of these embodiment, General Principle as defined herein can, in the situation that not departing from spirit or scope of the present utility model, realize in other embodiments.Therefore, this utility model will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Claims (3)
1. the device for the online detection of artificial organ surface blood coagulation, it is characterized in that, this device comprises Fibre Optical Sensor, described Fibre Optical Sensor is fixed on the surface of described artificial organ, the outside of described Fibre Optical Sensor is coated with one deck anticoagulant coatings, and described Fibre Optical Sensor is equally distributed multiple;
Described Fibre Optical Sensor comprises luminous source optical fiber and reception optical fiber, and described anticoagulant coatings is clear coat;
Described clear coat and Fibre Optical Sensor corresponding matching arrange, and form by judging that reflection ray power judges the sensing system of blood coagulation.
2. the device for the online detection of artificial organ surface blood coagulation as claimed in claim 1, is characterized in that, described Fibre Optical Sensor is array format and distributes.
3. the device for the online detection of artificial organ surface blood coagulation as claimed in claim 1, is characterized in that, described anticoagulant coatings covers Fibre Optical Sensor completely, is mediate contact between described Fibre Optical Sensor and blood.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420228507.8U CN203988366U (en) | 2014-05-06 | 2014-05-06 | A kind of for the online device detecting of artificial organ surface blood coagulation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420228507.8U CN203988366U (en) | 2014-05-06 | 2014-05-06 | A kind of for the online device detecting of artificial organ surface blood coagulation |
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| Publication Number | Publication Date |
|---|---|
| CN203988366U true CN203988366U (en) | 2014-12-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420228507.8U Expired - Fee Related CN203988366U (en) | 2014-05-06 | 2014-05-06 | A kind of for the online device detecting of artificial organ surface blood coagulation |
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| Country | Link |
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| CN (1) | CN203988366U (en) |
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2014
- 2014-05-06 CN CN201420228507.8U patent/CN203988366U/en not_active Expired - Fee Related
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141210 Termination date: 20170506 |