CN203958732U - A kind of powder and liquid double-chamber bag production system - Google Patents
A kind of powder and liquid double-chamber bag production system Download PDFInfo
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- CN203958732U CN203958732U CN201420021147.4U CN201420021147U CN203958732U CN 203958732 U CN203958732 U CN 203958732U CN 201420021147 U CN201420021147 U CN 201420021147U CN 203958732 U CN203958732 U CN 203958732U
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- bag
- district
- sterilizing
- chamber
- production system
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 78
- 239000007788 liquid Substances 0.000 title claims abstract description 66
- 239000000843 powder Substances 0.000 title claims abstract description 41
- 230000001954 sterilising effect Effects 0.000 claims abstract description 64
- 238000012856 packing Methods 0.000 claims abstract description 32
- 238000001514 detection method Methods 0.000 claims abstract description 30
- 238000007689 inspection Methods 0.000 claims abstract description 18
- 238000002360 preparation method Methods 0.000 claims abstract description 16
- 238000000034 method Methods 0.000 claims abstract description 10
- 238000007789 sealing Methods 0.000 claims abstract description 10
- 238000001035 drying Methods 0.000 claims abstract description 9
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229910052782 aluminium Inorganic materials 0.000 claims abstract description 8
- 239000004411 aluminium Substances 0.000 claims abstract description 8
- 238000012423 maintenance Methods 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 9
- 230000005540 biological transmission Effects 0.000 claims description 5
- 238000012546 transfer Methods 0.000 claims description 5
- 238000012858 packaging process Methods 0.000 claims description 2
- 238000005538 encapsulation Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 abstract description 8
- 239000000203 mixture Substances 0.000 abstract description 8
- 238000004806 packaging method and process Methods 0.000 abstract description 7
- 238000005516 engineering process Methods 0.000 abstract description 4
- 239000003814 drug Substances 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000009191 jumping Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
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Abstract
The utility model discloses a kind of powder and liquid double-chamber bag production system, in this production system, lower bag of cool bag, liquid chamber leak detection and the rejecting of bad bag, pulvis packing, bag sealing process after bag preparation in dosing, bag embedding, the inspection of liquid chamber lamp, sterilizing, sterilizing-drying, sterilizing are all arranged on to clean area; Produce the auxiliary clean rank clean area needing with auxiliary operation that is arranged on; Aluminium film is covered in the lamp inspection of powder chamber, powder chamber, packaging is arranged on common Production Regional; Its entirety forms the brand-new production system of a letter lid liquor and pulvis production.The technological requirement that the utility model is produced according to the particularity of two chambers bag product self, according to two kinds of formulations, the whole production system of rationally arranging, both realized the production technology of two kinds of formulations had been organically combined, and can improve again space availability ratio, ensured whole production system high-efficiency operation simultaneously.
Description
Technical field
The utility model relates to aseptic medicine production field, refers in particular to powder and liquid double-chamber bag production system.
Background technology
Powder and liquid double-chamber bag product is a kind of medicine that comprises transfusion and two kinds of formulations of pulvis of domestic new research and development, is characterized in filling respectively liquor transfusion and medicine powder with non-PVC infusion bag, forms an entirety, is convenient to clinical use, improves drug safety.Its production process letter lid non-PVC soft bag transfusion produce and pulvis packing two major parts.
Non-PVC soft bag transfusion is produced existing ripe production system, comprising: in dosing, bag embedding, sterilizing, bag preparation, sterilizing, lower bag of sterilizing, lamp are examined, pack and produce the operations such as auxiliary, and its flow process as shown in Figure 1.
Wherein dosing is arranged on C level clean area, and bag embedding is arranged on C+A level clean area, produces the auxiliary clean area that is arranged on the clean rank needing with auxiliary operation, and other is all arranged on common Production Regional.
Pulvis packing also has comparatively ripe technological process production system, comprising: cleaning, dry sterilization, packing, jump a queue, sealing, lamp inspection, packaging and produce the operations such as auxiliary, its flow process is as shown in Figure 2.
Wherein clean and be arranged on C level clean area, dry sterilization, packing, jumping a queue is arranged on B+A level region, roll lid and be arranged on C+A level region, produce the auxiliary clean area that is arranged on the clean rank needing with auxiliary operation, other is all arranged on common Production Regional.
Due to the particularity of two chambers bag product, its production process is not simply by the stack of two kinds of formulation pharmaceutical production systems, the technological requirement of how to produce according to the particularity of two chambers bag product self, according to two kinds of formulations, the whole production system of rationally arranging, both realized the production technology of two kinds of formulations had been organically combined, can improve again space availability ratio, ensure whole production system high-efficiency operation simultaneously, become the problem that technical personnel need to solve.
Utility model content
The problem existing for prior art, the purpose of this utility model is to provide a kind of production system by pulvis and liquor to be optimized the powder and liquid double-chamber bag production system of combination
For achieving the above object, a kind of powder and liquid double-chamber bag production system of the utility model, is all arranged on clean area by lower bag of cool bag, liquid chamber leak detection and the rejecting of bad bag, pulvis packing, bag sealing process after bag preparation in dosing, bag embedding, the inspection of liquid chamber lamp, sterilizing, sterilizing-drying, sterilizing in this production system; Produce the auxiliary clean area that is arranged on the clean rank needing with auxiliary operation; Aluminium film is covered in the lamp inspection of powder chamber, powder chamber, packaging is arranged on common Production Regional; Its entirety forms the brand-new production system of a letter lid liquor and pulvis production.
Further, described production system comprises dosing district, bag embedding district, liquid chamber Deng Jian district, bag area in preparation in sterilizing, sterilizing district, cool bag Xia Dai district after sterilizing, liquid chamber leak detection and bad bag are rejected district, pulvis packing district, bag finalization area, Fen Shidengjian district, Fen Shifulv film district and bagging area, its respectively with described dosing, bag embedding, the inspection of liquid chamber lamp, in sterilizing, bag is prepared, sterilizing-drying, lower bag of cool bag after sterilizing, liquid chamber leak detection and bad bag are rejected, pulvis packing, bag sealing, the lamp inspection of powder chamber, aluminium film is covered in powder chamber, packaging process is corresponding, between each station, be provided with material transfer device.
Further, other the second production auxiliary region being provided with for plant maintenance maintenance, the region in described pulvis packing district; The other first production auxiliary region that is provided with, region in described dosing district, bag embedding district and liquid chamber Deng Jian district; Described liquid chamber leak detection and bad bag are rejected other the 3rd production auxiliary region that is provided with, region in district, bag finalization area, Fen Shidengjian district.
Further, after described sterilizing, cool bag Xia Dai district and liquid chamber leak detection and bad bag are rejected between district and are isolated by air-lock, the air pressure of air-lock is greater than cool bag Xia Dai district after sterilizing, liquid chamber leak detection and bad bag rejects the air pressure of area, to ensure that the air that cool bag Xia Dai district after sterilizing, liquid chamber leak detection and bad bag are rejected Liang Ge region, district does not circulate mutually.
Further, described pulvis packing district be arranged on one be the Special Areas of relative negative pressure with surrounding environment in, the passage place that this Special Areas is connected with surrounding environment is provided with gas curtain fender guard.
Further, after described sterilizing, in cool bag Xia Dai district and sterilizing, the material transmission channels between bag area in preparation is controlled by pressure reduction.
Further, in described dosing district, liquid chamber Deng Jian district, sterilizing, bag area in preparation is C level clean area.
Further, described bag embedding district is C+A level clean area.
Further, after described sterilizing, cool bag Xia Dai district, liquid chamber leak detection and bad bag rejecting district, pulvis packing district, finalization area are B+A level clean area
Further, described Fen Shidengjian district, Fen Shifulv film district, bagging area are common Production Regional.
The technological requirement that the utility model is produced according to the particularity of two chambers bag product self, according to two kinds of formulations, the whole production system of rationally arranging, both realized the production technology of two kinds of formulations had been organically combined, and can improve again space availability ratio, ensured whole production system high-efficiency operation simultaneously.
Brief description of the drawings
Fig. 1 is the flow scheme of non-PVC soft bag transfusion production system in prior art;
Fig. 2 is the flow scheme of pulvis packing production system in prior art;
Fig. 3 is flow scheme of the present utility model;
Fig. 4 is the each operation of the utility model production system schematic diagram of arranging.
Detailed description of the invention
Below, with reference to accompanying drawing, the utility model is more fully illustrated, shown in the drawings of exemplary embodiment of the present utility model.But the utility model can be presented as multiple multi-form, and should not be construed as the exemplary embodiment that is confined to narrate here.But, these embodiment are provided, thereby make the utility model comprehensively with complete, and scope of the present utility model is fully conveyed to those of ordinary skill in the art.
For ease of explanation, here can use such as " on ", the space relative terms such as D score " left side " " right side ", the relation for element shown in instruction diagram or feature with respect to another element or feature.It should be understood that except the orientation shown in figure, spatial terminology is intended to comprise the different azimuth of device in using or operating.For example, if the device in figure is squeezed, be stated as the element that is positioned at other elements or feature D score will be positioned at other elements or feature " on ".Therefore, exemplary term D score can comprise upper and lower orientation both.Device can otherwise be located (90-degree rotation or be positioned at other orientation), and the relative explanation in space used here can correspondingly be explained.
A kind of powder and liquid double-chamber bag production system of the utility model, the production system of pulvis and liquor is optimized to combination, lower bag of cool bag, liquid chamber leak detection, the rejecting of bad bag, pulvis packing, bag sealing process after bag preparation in dosing, bag embedding, the inspection of liquid chamber lamp, sterilizing, sterilizing-drying, sterilizing are all arranged on to clean area; Produce the auxiliary clean area that is arranged on the clean rank needing with auxiliary operation.Aluminium film is covered in the lamp inspection of powder chamber, powder chamber, packaging is arranged on common Production Regional, forms the brand-new production system that a letter lid liquor and pulvis are produced.
As Fig. 3, shown in Fig. 4, corresponding with each operation, the utility model powder and liquid double-chamber bag production system comprises: dosing district 1, bag embedding district 2, liquid chamber Deng Jian district 3, bag area in preparation 5 in sterilizing, sterilizing district 6, cool bag Xia Dai district 7 after sterilizing, liquid chamber leak detection and bad bag are rejected district 9, pulvis packing district 11, bag finalization area 12, Fen Shidengjian district 13, Fen Shifulv film district 14, bagging area 15, the first production auxiliary region 4, the second production auxiliary region 16, the 3rd production auxiliary region 17 stations such as grade, between each station, be provided with material transfer device, and carry out as shown by arrows in FIG. the transmission of material by material transfer device, sterilizing district 6 carries out in special bactericidal unit.
In dosing district 1, liquid chamber Deng Jian district 3, sterilizing, bag area in preparation 5 is C level clean area, bag embedding district 2 is C+A level clean area, after sterilizing, cool bag Xia Dai district 7, liquid chamber leak detection and bad bag rejecting district 9, pulvis packing district 11, finalization area 12 are B+A level clean area, and Fen Shidengjian district 13, Fen Shifulv film district 14, bagging area 15 are common Production Regional.
After sterilizing, in cool bag Xia Dai district 7 and sterilizing, the material transmission channels between bag area in preparation 5 is controlled by pressure reduction, ensures that the outside face of sterilising prods 18 is not contaminated in circulation, course of conveying.
After sterilizing, cool bag Xia Dai district 7 and liquid chamber leak detection and bad bag are rejected between district 9 and are isolated by air-lock 8, the air pressure of air-lock 8 is greater than cool bag Xia Dai district 7 and liquid chamber leak detection and bad bag after sterilizing rejects the air pressure in 9 regions, district, do not circulate mutually with liquid chamber leak detection and bad bag of air of rejecting 9 two regions, district with cool bag Xia Dai district 7 after ensureing sterilizing, be convenient to the control of temperature and humidity in liquid chamber leak detection and bad bag rejecting 9 regions, district.
Pulvis packing district 11 be arranged on one be the Special Areas of relative negative pressure with surrounding environment in; the passage place that this Special Areas is connected with surrounding environment is provided with gas curtain fender guard 10; be convenient to pressure reduction, temperature, the humidity control in this region; both meet the requirement of pulvis packing to environment temperature, humidity, prevented again fly out packing region and to environment of pulvis.
For ease of the plant maintenance maintenance in pulvis packing district 11, reduce the pollution of plant maintenance inspection operation to crucial Production Regional, other the second production auxiliary region 16 that is provided with the cleaning of C level, 11 regions, pulvis packing district.
The clean rank in the first production auxiliary region 4,17 regions, the 3rd production auxiliary region is all by the requirement setting of auxiliary operation.
As shown by arrows in FIG., technological process when the utility model production system is worked is: after bag preparation in dosing, bag embedding, the inspection of liquid chamber lamp, sterilizing, sterilizing-drying, sterilizing, lower bag of cool bag, liquid chamber leak detection are covered aluminium film, packaging with badly bag rejecting, pulvis packing, sealing, the inspection of powder chamber lamp, powder chamber.
The feature of the utility model powder and liquid double-chamber bag production system is:
1) production system of pulvis and liquor is optimized to combination, lower bag of cool bag, liquid chamber leak detection, the rejecting of bad bag, pulvis packing, sealing process after bag preparation in dosing, bag embedding, the inspection of liquid chamber lamp, sterilizing, sterilizing-drying, sterilizing are all arranged on to clean area, the lamp inspection of powder chamber, aluminium film is covered in powder chamber, packaging is arranged on common Production Regional system;
2) liquor lamp inspection operation is mentioned in sterilizing before bag, and this station is placed in C level clean area, in completing liquor Control of Internal Quality, ensure that product external surfaces is not contaminated, produce and create conditions for pulvis;
3) bag in liquor sterilizing is prepared to (sterilizing cup) and be arranged in C level clean area, ensure that product external surfaces is not contaminated in circulation, course of conveying, produce and create conditions for pulvis;
4) lower liquor sterilizing cool bag bag region (chamber after sterilizing) is arranged in B+A level clean area, after sterilizing, between chamber and cup, article transmission channels is controlled by pressure reduction, ensure that sterilising prods outside face is not contaminated in circulation, course of conveying, for powder product quality provides safeguard;
5) leak detection of liquor liquid chamber and bad bag rejecting are arranged in B+A level clean area, and effectively isolate by air-lock is set with the lower bag region of sterilizing cool bag (chamber after sterilizing), air-lock pressure is greater than chamber and liquid chamber leak detection and bad bag after sterilizing and rejects a district, after guarantee sterilizing, chamber and the leak detection of liquor liquid chamber and a bad bag rejecting regional air do not circulate mutually, be convenient to the leak detection of liquor liquid chamber and bad bag rejecting regional temperature, humidity control, and sterilising prods outside face is not contaminated in circulation, course of conveying, for powder product quality provides safeguard;
6) pulvis packing is arranged in B+A clean area, and packaging operation be arranged on one be the Special Areas of relative negative pressure with surrounding environment in, and the passage place being connected with surrounding environment at this Special Areas arranges gas curtain fender guard, be convenient to pressure reduction and warm, the humidity control in packing region, prevent from polluting; Be designed with C level auxiliary region on side, packing region, for dispensing apparatus Maintenance and Repair, reduce Maintenance and Repair and operate the pollution to crucial Production Regional, ensure the required clean environment of pulvis packing, for powder product quality provides safeguard;
7) after sealing, be provided with powder chamber lamp inspection operation, check pulvis packing and seal quality;
8) be provided with powder chamber and cover aluminium membrane process, the medicine that powder is indoor is effectively protected.
Claims (1)
1. a powder and liquid double-chamber bag production system, it is characterized in that, in this production system, cool bag Xia Dai district, liquid chamber leak detection district and bad bag rejecting district, pulvis encapsulation region, bag sealing process district after bag area in preparation, sterilizing-drying district, sterilizing in dosing district, bag embedding district, liquid chamber Deng Jian district, sterilizing are all arranged on to clean area; Production auxiliary region is arranged on the clean rank clean area needing with auxiliary operation; Fen Shidengjian district, Fen Shifulv film district, bagging area are arranged on common Production Regional; Between each station, be provided with material transfer device, its entirety forms the brand-new production system of a letter lid liquor and pulvis production.
2. powder and liquid double-chamber bag production system as claimed in claim 1, it is characterized in that, described production system comprises dosing district, bag embedding district, liquid chamber Deng Jian district, bag area in preparation in sterilizing, sterilizing-drying district, cool bag Xia Dai district after sterilizing, liquid chamber leak detection and bad bag are rejected district, pulvis packing district, bag finalization area, Fen Shidengjian district, Fen Shifulv film district and bagging area, its respectively with dosing, bag embedding, the inspection of liquid chamber lamp, in sterilizing, bag is prepared, sterilizing-drying, lower bag of cool bag after sterilizing, liquid chamber leak detection and bad bag are rejected, pulvis packing, bag sealing, the lamp inspection of powder chamber, aluminium film is covered in powder chamber, packaging process is corresponding, between each station, be provided with material transfer device.
3. powder and liquid double-chamber bag production system as claimed in claim 2, is characterized in that, the other second production auxiliary region being provided with for plant maintenance maintenance, region in described pulvis packing district; The other first production auxiliary region that is provided with, region in described dosing district, bag embedding district and liquid chamber Deng Jian district; Described liquid chamber leak detection and bad bag are rejected other the 3rd production auxiliary region that is provided with, region in district, bag finalization area, Fen Shidengjian district.
4. powder and liquid double-chamber bag production system as claimed in claim 2, it is characterized in that, after described sterilizing, cool bag Xia Dai district and liquid chamber leak detection and bad bag are rejected between district and are isolated by air-lock, the air pressure of air-lock is greater than cool bag Xia Dai district after sterilizing, liquid chamber leak detection and bad bag rejects the air pressure of area, to ensure that the air that cool bag Xia Dai district after sterilizing, liquid chamber leak detection and bad bag are rejected Liang Ge region, district does not circulate mutually.
5. powder and liquid double-chamber bag production system as claimed in claim 2, is characterized in that, described pulvis packing district be arranged on one be the Special Areas of relative negative pressure with surrounding environment in, the passage place that this Special Areas is connected with surrounding environment is provided with gas curtain fender guard.
6. powder and liquid double-chamber bag production system as claimed in claim 2, is characterized in that, after described sterilizing, in cool bag Xia Dai district and sterilizing, the material transmission channels between bag area in preparation is controlled by pressure reduction.
7. powder and liquid double-chamber bag production system as claimed in claim 2, is characterized in that, in described dosing district, liquid chamber Deng Jian district, sterilizing, bag area in preparation is C level clean area.
8. powder and liquid double-chamber bag production system as claimed in claim 2, is characterized in that, described bag embedding district is C+A level clean area.
9. powder and liquid double-chamber bag production system as claimed in claim 2, is characterized in that, after described sterilizing, cool bag Xia Dai district, liquid chamber leak detection and bad bag rejecting district, pulvis packing district, finalization area are B+A level clean area.
10. powder and liquid double-chamber bag production system as claimed in claim 2, is characterized in that, described Fen Shidengjian district, Fen Shifulv film district, bagging area are common Production Regional.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420021147.4U CN203958732U (en) | 2014-01-14 | 2014-01-14 | A kind of powder and liquid double-chamber bag production system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420021147.4U CN203958732U (en) | 2014-01-14 | 2014-01-14 | A kind of powder and liquid double-chamber bag production system |
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| Publication Number | Publication Date |
|---|---|
| CN203958732U true CN203958732U (en) | 2014-11-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420021147.4U Expired - Lifetime CN203958732U (en) | 2014-01-14 | 2014-01-14 | A kind of powder and liquid double-chamber bag production system |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104554910A (en) * | 2015-01-09 | 2015-04-29 | 富阳市福士得食品有限公司 | Packaged food packaging system |
| CN104608973A (en) * | 2015-01-28 | 2015-05-13 | 四川科伦药业股份有限公司 | Full-automatic liquid-liquid multi-chamber bag manufacturing, filling and sealing machine |
| CN105599937A (en) * | 2016-03-09 | 2016-05-25 | 四川科伦药业股份有限公司 | Full-automatic liquid-liquid douche bag making filling-sealing machine |
-
2014
- 2014-01-14 CN CN201420021147.4U patent/CN203958732U/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104554910A (en) * | 2015-01-09 | 2015-04-29 | 富阳市福士得食品有限公司 | Packaged food packaging system |
| CN104608973A (en) * | 2015-01-28 | 2015-05-13 | 四川科伦药业股份有限公司 | Full-automatic liquid-liquid multi-chamber bag manufacturing, filling and sealing machine |
| CN104608973B (en) * | 2015-01-28 | 2016-09-07 | 四川科伦药业股份有限公司 | A kind of Full Automatic Liquid liquid multi-chamber-bag bag making, filling and sealing machine |
| CN105599937A (en) * | 2016-03-09 | 2016-05-25 | 四川科伦药业股份有限公司 | Full-automatic liquid-liquid douche bag making filling-sealing machine |
| CN105599937B (en) * | 2016-03-09 | 2018-02-27 | 四川科伦药业股份有限公司 | A kind of Full Automatic Liquid liquid douche bag bag making, filling and sealing machine |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20141126 |