CN203886559U - Interface component for packaging microfluid device - Google Patents
Interface component for packaging microfluid device Download PDFInfo
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- CN203886559U CN203886559U CN201320640193.8U CN201320640193U CN203886559U CN 203886559 U CN203886559 U CN 203886559U CN 201320640193 U CN201320640193 U CN 201320640193U CN 203886559 U CN203886559 U CN 203886559U
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- mouthpiece
- ports
- port
- mouthpiece according
- microfluid
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- Expired - Lifetime
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- 238000004806 packaging method and process Methods 0.000 title 1
- 239000012530 fluid Substances 0.000 claims abstract description 48
- 238000000018 DNA microarray Methods 0.000 claims description 36
- 230000006835 compression Effects 0.000 claims description 11
- 238000007906 compression Methods 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 10
- 238000012856 packing Methods 0.000 claims description 5
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims 1
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 claims 1
- 238000004987 plasma desorption mass spectroscopy Methods 0.000 claims 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 description 10
- 238000000034 method Methods 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 239000004033 plastic Substances 0.000 description 6
- 229920003023 plastic Polymers 0.000 description 6
- 238000007789 sealing Methods 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 3
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 3
- 239000004926 polymethyl methacrylate Substances 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000007711 solidification Methods 0.000 description 2
- 230000008023 solidification Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 208000005189 Embolism Diseases 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000002388 eustachian tube Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229920001684 low density polyethylene Polymers 0.000 description 1
- 239000004702 low-density polyethylene Substances 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 238000004377 microelectronic Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000003032 molecular docking Methods 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229920005573 silicon-containing polymer Polymers 0.000 description 1
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- 210000002700 urine Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Abstract
The utility model relates to an interface component. The interface component comprises a plurality of external ports and a plurality of jointing conduits, wherein the external ports are configured to be communicated with ports of a plurality of fluid conveying platforms; the jointing conduits are configured to be connected with fluid of ports of a plurality of microfluid biological chips; the tolerances of the external ports and/or the jointing conduits are obviously smaller than the tolerance of the ports of the microfluid biological chips.
Description
Technical field
The present invention relates to a kind of mouthpiece for microfluidic device.
Background technology
System based on microfluid has been to use polymer by using glass/silicon polymer to manufacture and evolving.This polymers manufacturing method has substituted from microelectronics industry (MEMS) and has used next technology, makes their manufacture simpler and cheap.The biocompatibility of polymer makes them become a kind of chip lab (LOC) for a lot of diagnostic application or the material of the more attractive of (POC) equipment of looking after of fixing a point is selected.Dimethyl silicone polymer (PDMS), a kind of soft rubber as polymer, in research and development of products and academia as welcome material occur manufacturing/produce microfluidic device, surpass traditional rigid plastics, Merlon (PC) for example, polymethyl methacrylate (PMMA), polypropylene (PP) and polystyrene.Low mainly due to the cost of manufacturing, the micro-fluid chip based on PDMS is suitable for manual machinery processing (manual machining).PDMS also has outstanding optics, machinery and chemical property.And PDMS compares with spray casting has high repeatability and accuracy, this also makes it become the desirable micron requiring with high dimensional accuracy for a large amount of manufactures to time materials of the micro-fluid chip of micron pattern.
Yet, along with decennary the developing rapidly in the past of the equipment based on microfluid, these equipment connections are remained to a kind of technological challenge to the connector product (such as Eustachian tube, syringe pump, force (forcing) pump etc.) of macrocosm.And connector is resize ratio easily, conventionally make the bulky of equipment.The flexible character of adding PDMS makes this problem extremely challenging.The solution that the microfluidic device of ting model need to customize conventionally, does not have the Package Tactics for " a kind of model is applicable to all " of the equipment based on PDMS conventionally.Be different from integrated circuit (IC) chip, the standard of not packing for microfluidic device.
In this regard, when microfluidic device carries out transition from laboratory to business form, PDMS is not desirable material conventionally.The flexible feature of PDMS makes the clamping based on compression very difficult to realize leakproof seal.When being that while having the self-reacting device of integrated fluid conveyor module, the plastic chip that hard material is made is normally preferred by laboratory mechanism evolution.This is because compare with PDMS micro-fluid chip, rigid plastics chip is connected with fluid delivery apparatus easier.Yet it is a large amount of being dropped in the time and money of producing in rigid plastics chip, this is normally to the business-like obstacle of successful micro-fluid chip.Far and away, when microfluidic device is transitioned into commercialization form from laboratory, this is a problem.
Summary of the invention
Put it briefly, the present invention proposes a kind of non-deformable mouthpiece for deformable micro-fluid chip.The port of mouthpiece can be made closed tolerance, and can be easily with chip on high tolerance port match, in the manufacturing, this may have superiority.Therefore, closed tolerance mouthpiece port can easily must match and/or use with fluid delivery platform compression seal.
In concrete manifestation of the present invention, provide a kind of mouthpiece, having comprised:
A plurality of outside ports, are configured to be communicated with (fluidically communicate) with a plurality of port fluids of fluid delivery platform;
A plurality of joint conduits, are configured to be connected with the port fluid of a plurality of microfluid biochips;
Wherein, the tolerance of a plurality of outside ports and/or a plurality of joint conduits is obviously less than the tolerance of a plurality of ports of microfluid biochip.Each of described a plurality of outside ports comprises recess, and described recess is configured to for seal, the group that described seal selects free O type ring, pad and packing ring to form.
A plurality of rib structures that further comprise the inner surface place that is positioned at described mouthpiece.
Further comprise at least one receptor that is positioned at outer surface, described at least one receptor is configured to the manifold of described mouthpiece and described fluid delivery platform to aim at.
Each of described a plurality of joint conduits is conical butt.
Described mouthpiece is configured to seal mutually with non-removable lid.
Described mouthpiece right and wrong are deformable.
Each outside port engages conduit with each be coaxial, and each outside port is configured to the joint catheter fluid coaxial with each and is communicated with.
Described a plurality of ports of a plurality of joint conduits and microfluid biochip closely cooperate to provide leakproof seal.
Each engages the angle of inclination of conduit between 0 °-15 °.
Each open end that engages conduit has than the outer dia of the little 0.1mm-1mm of inside diameter of described a plurality of ports of described microfluid biochip.
Each mouthpiece end that engages conduit has than the outer dia of the large 0.2mm-1.5mm of described a plurality of port diameter of described microfluid biochip.
Further comprise the microfluid biochip being contained in described mouthpiece.
Further comprise that anti-tampering lock is to stop chronically described microfluid biochip to be removed from described mouthpiece.
Described microfluid biochip is to be made by dimethione PDMS or flexible soft polymeric material.
Fluid delivery platform or a diagnostic device, the outside port that the mouthpiece that provides with above-mentioned arbitrary technical scheme is provided forms compression seal.
Accompanying drawing explanation
In order to understand fully the present invention and to be easy to illustrate its actual effect, now by nonrestrictive example of the present invention, be only preferred embodiment described, described description is with reference to the illustrative embodiments of following.
Fig. 1 shows the first perspective view of the mouthpiece of example embodiment.
Fig. 2 shows first photo of mouthpiece.
Fig. 3 shows the second perspective view of mouthpiece.
Fig. 4 shows second photo of mouthpiece.
Fig. 5 shows the front view of the lid that can be used for mouthpiece.
Fig. 6 shows the photo of lid.
Fig. 7 shows the photo of the mouthpiece of lid and parallel placement.
Fig. 8 shows the photo of the mouthpiece of the view reverse side shown in lid and Fig. 7.
Fig. 9 shows the photo for assessment of the manifold mechanism of mouthpiece.
Figure 10 shows the schematic diagram for pressure test mechanism.
Figure 11 shows the photo of the pressure test mechanism of Figure 10.
Figure 12 (a) to (d) shows a series of photos of connecting interface part and biochip.
Figure 13 shows the photo of the mouthpiece of bearing compression.
Figure 14 shows the cutaway view of the mouthpiece of the manifold that is connected to fluid delivery platform, and described mouthpiece is born compression.
The specific embodiment
Embodiment can provide a kind of mouthpiece with port, allows the microfluidic device based on PDMS be easy to and be connected reliably with fluid delivery platform.Described mouthpiece can overcome the problem of bringing when needing fluid delivery platform and microfluidic device based on PDMS is connected.Therefore, mouthpiece can be used as the basis that relates to the economic solution of microfluidic device for all.
With reference to figure 1-8, the various views of the mouthpiece 20 with port are provided, show figure or the photo of the assembly/part separately of mouthpiece 20.Mouthpiece 20 comprises a plurality of outside ports 22, is configured to be communicated with a plurality of fluid delivery platform (not shown) fluids.Especially, a plurality of outside ports 22 are typically connected with the manifold being integrated on the instrument of fluid delivery platform, such as, for example, force (forcing) pump, syringe pump etc.Each of a plurality of outside ports 22 comprises recess 24, is configured to adhere to O type ring 26.Alternative, pad, packing ring or analog when bearing compression for leakproof seal is provided.O type ring 26 is for providing the sealing of manifold.Diameter/the degree of depth of recess is less than the about 0.2-0.6mm of outer dia of O type ring 26, to guarantee that O type ring can be sitting in each recess 24 tightly.Mouthpiece 20 also comprises and is positioned at least one receptor (receptor) 34 of outer surface 36 with the manifold of calibration interface part 20 and fluid delivery platform.
Mouthpiece 20 also comprises a plurality of joint conduits 28, is configured to be communicated with the port fluid of a plurality of microfluid biochips 50.Each of a plurality of joint conduits 28 is conical butt, and each joint conduit 28 is coaxial with outside port 22.Each outside port 22 is configured to be communicated with each coaxial joint conduit 28 fluid.Outside port 22 provides and in mouthpiece 20, leads to the through hole that engages conduit 28.Port (being particularly integrated in the instrument of fluid delivery platform) on the manifold of these outside port 22 alignment fluid delivery platforms, fluid is communicated with microfluid biochip 50 and fluid delivery platform.It in microfluid biochip 50 is arbitrary liquid or gas that described fluid can be pumped into.Described fluid can be the biological sample being pumped into for the micro-fluid chip 50 of diagnostic application, for example, and blood, saliva, leural effusion, urine etc.
Each of the port of each of a plurality of joint conduits 28 and a plurality of micro-fluid chip 50 closely cooperates to provide leakproof seal.Figure 12 shows outside port 22 and engages the passage 25 that conduit 28 shares a homogeneous diameter.Yet outside port 22 and the diameter that engages conduit 28 can be different, for example, as long as can keep suitable flow velocity (0.01-5ml/min) to avoid turbulent flow.In addition keep outside port 22 and engage the relative diameter uniformly of conduit 28, having avoided damaging the high shear environment of cell.An open end 29 that engages conduit 28 is compared with mouthpiece end 27, has less diameter.In solidification process, due to the contraction of material, a plurality of ports 49 of microfluid biochip 50 are distortions.As shown in Figure 12 (a)-(d), in engaging process, open end 29 is impelled deformable port 49 to closely cooperate and the leakproof seal of docking port part end 27 is provided.
Because microfluid biochip 50 is made by PDMS conventionally, as shown in Figure 8, when microfluid biochip aligns with a kind of suitable mode and mouthpiece 20, each of a plurality of ports 49 of microfluid biochip 50 applicable to each of (being closely tied in) a plurality of joint conduits 28 so that leakproof seal to be provided.
Microfluid biochip 50 can be of different sizes (thickness, range, width).The outer surface that it should be understood that 4 joint conduits 28 also can serve as the alignment feature of microfluid biochip 50.The degree of depth of the insertion of a plurality of ports 49 of assembling (closely cooperating) microfluid biochip 50 when engaging conduit 28 (be inserted into chip 50 each port each engage the degree of depth of conduit 28) is definite by the thickness of PDMS mould and the height of mouthpiece 20.
Each zone of reasonableness that engages the angle of inclination of conduit 28 is between 0 °-15 °.Each engage conduit 28 for conical butt and have be less than port 49 diameter, outer end diameter at 0.1mm to the open end 29 between 1mm.Each engages conduit 28 and closely cooperates with port 49, makes them can insert the 50-90% of the thickness of microfluid biochip 50.The outer dia of the mouthpiece end 27 of each joint conduit 28, between 0.2mm-1.5mm, is greater than the diameter of port 49, to guarantee engaging good compression seal between conduit 28 and port 49.
Should be understood that, a plurality of outside ports 22 are more easily implemented to closely cooperating of microfluid biochip 50 than a plurality of joint conduits 28 to the connection of manifold.This is mainly that microscopic dimensions and the flexibility of the port 49 of microfluid biochip 50 cause larger difficulty due to when engaging conduit 28 pairing with mouthpiece 20 a plurality of.The position of a plurality of outside ports 22 and a plurality of joint conduits 28 is fixed in mouthpiece 20.In view of the port 49 of microfluid biochip 50 is flexibly, the port 49 of microfluid biochip 50 can closely cooperate and be fixed to the upper with a plurality of conduits 28 that engage that adhere to, to guarantee that mouthpiece 20 can circulate for fluid between fluid delivery platform and microfluid biochip 50.In this respect, the tolerance (relating to physical arrangement) of a plurality of outside ports 22 and a plurality of joint conduits 28 is than the tolerance (relating to physical arrangement) of the port 49 of a plurality of microfluid biochips 50 (being easier to distortion in solidifying) little (more accurate or reliably) significantly.Therefore,, due to the little tolerance of outside port 22 and joint conduit 28, the high deformation of a plurality of ports 49 can regulate.The tolerance of PDMS thickness is ± 0.5mm.In solidification process, due to the contraction of the 2-5% of PDMS, also can reach ± 0.5mm of the tolerance of a plurality of ports.According to the Tool and Die Technology and the material that use, in all directions, in can be controlled at ± 0.1mm of the dimensional tolerance of mouthpiece 20.
Mouthpiece 20 use rigid plastics are made, for example, and PC, PMMA, PVC, HDPE, LDPE, PS, PP etc.Use the economic method with extensibility easily to manufacture mouthpiece 20, for example, injection moulding or other plastic moulds technology.Mouthpiece 20 right and wrong are deformable, at inner surface 32 places of mouthpiece 20, also comprise a plurality of rib structures 30.A plurality of rib structures 30 at inner surface 32 provide structural rigidity, and when bearing high compression load, stop the infringement to the microfluid biochip 50 adhering to of subsiding and therefore causing of mouthpiece 20.This is vital, because in order to reach good sealing between mouthpiece 20 and micro-fluid chip 50, high compressive load is absolutely necessary.There is no mouthpiece 20, for applying constant load to micro-fluid chip 50, micro-fluid chip 50 not being produced significant deformation and damaged will be a challenge.
Once micro flow chip 50 closely cooperates with mouthpiece 20, mouthpiece 20 is subsequently with lid 60 sealings (being shown in Fig. 5 and Fig. 6).As shown in Figure 12 (a), in assembling process, micro-fluid chip 50 roughly manually aligns with a plurality of conduits 28 that engage.As shown in Figure 12 (b), then chip 50 is crushed on and engages on conduit 28 so that deformable port 49 can be closely cooperated forcibly.As shown in Figure 12 (c), final lid 60 approaches with constraint micro flow chip 50.Use is integrated at least one anti-tampering lock 62 of lid 60, and the constraint (lock) that lid 60 can be long-term is on mouthpiece 20.This will guarantee reliability and stop recycling.According to the thickness of chip 50, from compression, be fitted to the process that engages conduit 28, it likely suspends.Mouthpiece 20 can be that standard specification is to be applicable to the scope of the different moulds of chip 50 like this.For higher force applications, the bottom that it also can be designed to push lid 60 inside can not separate to guarantee in use to seal.
Figure 12 (d), 13 and 14 shows the mouthpiece of just bearing compression 20 of the manifold 10 that is connected to fluid delivery platform.O type ring 26 is compressed, therefore, provides the sealing of the high reliability from manifold 10 to micro-fluid chip 50.
Carry out the maximum pressure of test to determine that mouthpiece 20 can be born.Use aluminium (as shown in Figure 9) manufacture manifold 99 with imitate the typical automated system based on microfluid mouthpiece.As shown in Figure 10, in test, described manifold 99 connects initial syringe 100 and pressure gauge 120.Practical set-up has been shown in Figure 11.The initial syringe 100 of the full air of punching drives the embolism (with adapter assembling) of water-filled secondary syringe 110.Allow to increase the pressure stimulating in syringe 110.The pressure gauge 120 that can measure 200kPa uses 3 logical T connectors to be connected to measure the pressure increasing in secondary syringe 110.In test, the load of 30N is applied to manifold 99, and primary injector 100 allows pump speed at 10ml/min, and the pressure of system can be monitored.Fault in operation is returned after error condition, and primary injector 100 also has the maximum pressure rating of 200kPa.Use above-mentioned device, the mouthpiece 20 illustrating is successfully used in bearing the pressure up to 200kPa in the end 15 minutes.Described mechanism for testing can be for the quality control of test proof and the mouthpiece 20 of principle in manufacture/assembling.
Be understandable that, mouthpiece 20 can provide 1 or more advantage:
-can provide based on the selectable sealing without obstruction generally popular in adhesive/glue;
-cost is low, because mouthpiece 20 can be made by economic method and material;
-repeatability, because mouthpiece 20 can adequately protect and the close-fitting microfluid biochip 50 of mouthpiece 20;
-low dead volume, during due to use mouthpiece 20, the loss of aforesaid liquid can be minimized, when working with low sample volume and expensive reagent, is important;
-can bear the high pressure of about 200kPa, it guarantees good sealing between mouthpiece 20 and micro-fluid chip 50; With
-extendible manufacture, due to the low cost of product.
Although preferred embodiment of the present invention has been described in above-mentioned explanation, related technical staff in the art it will be appreciated that, in multiple variation or the modification in detail that can draw without departing from the invention design or structure.
Claims (16)
1. a mouthpiece, comprising:
A plurality of outside ports, are configured to be communicated with a plurality of port fluids of fluid delivery platform;
A plurality of joint conduits, are configured to be connected with a plurality of port fluids of microfluid biochip;
It is characterized in that, the tolerance of a plurality of outside ports and/or a plurality of joint conduits is obviously less than the tolerance of a plurality of ports of microfluid biochip.
2. mouthpiece according to claim 1, is characterized in that, each of described a plurality of outside ports comprises recess, and described recess is configured to for seal, the group that described seal selects free O type ring, pad and packing ring to form.
3. mouthpiece according to claim 1, is characterized in that, further comprises a plurality of rib structures at the inner surface place that is positioned at described mouthpiece.
4. mouthpiece according to claim 1, is characterized in that, further comprises at least one receptor that is positioned at outer surface, and described at least one receptor is configured to the manifold of described mouthpiece and described fluid delivery platform to aim at.
5. mouthpiece according to claim 1, is characterized in that, each of described a plurality of joint conduits is conical butt.
6. mouthpiece according to claim 1, is characterized in that, described mouthpiece is configured to seal mutually with non-removable lid.
7. mouthpiece according to claim 1, is characterized in that, described mouthpiece right and wrong are deformable.
8. mouthpiece according to claim 1, is characterized in that, each outside port engages conduit with each be coaxial, and each outside port is configured to the joint catheter fluid coaxial with each and is communicated with.
9. mouthpiece according to claim 1, is characterized in that, described a plurality of ports of a plurality of joint conduits and microfluid biochip closely cooperate to provide leakproof seal.
10. mouthpiece according to claim 1, is characterized in that, each engages the angle of inclination of conduit between 0 °-15 °.
11. mouthpiece according to claim 1, is characterized in that, each open end that engages conduit has than the outer dia of the little 0.1mm-1mm of inside diameter of described a plurality of ports of described microfluid biochip.
12. mouthpiece according to claim 1, is characterized in that, each mouthpiece end that engages conduit has than the outer dia of the large 0.2mm-1.5mm of described a plurality of port diameter of described microfluid biochip.
13. mouthpiece according to claim 1, is characterized in that, further comprise the microfluid biochip being contained in described mouthpiece.
14. mouthpiece according to claim 13, is characterized in that, further comprise that anti-tampering lock is to stop chronically described microfluid biochip to be removed from described mouthpiece.
15. mouthpiece according to claim 13, is characterized in that, described microfluid biochip is to be made by dimethione PDMS or flexible soft polymeric material.
16. 1 kinds of fluid delivery platforms or diagnostic device, is characterized in that, is configured to and forms compression seal according to the outside port of the mouthpiece described in claim 1-15 any one.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320640193.8U CN203886559U (en) | 2013-10-16 | 2013-10-16 | Interface component for packaging microfluid device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320640193.8U CN203886559U (en) | 2013-10-16 | 2013-10-16 | Interface component for packaging microfluid device |
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| Publication Number | Publication Date |
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| CN203886559U true CN203886559U (en) | 2014-10-22 |
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| CN201320640193.8U Expired - Lifetime CN203886559U (en) | 2013-10-16 | 2013-10-16 | Interface component for packaging microfluid device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112041070A (en) * | 2018-05-15 | 2020-12-04 | 宝洁公司 | Microfluidic cartridge and microfluidic delivery device comprising same |
-
2013
- 2013-10-16 CN CN201320640193.8U patent/CN203886559U/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112041070A (en) * | 2018-05-15 | 2020-12-04 | 宝洁公司 | Microfluidic cartridge and microfluidic delivery device comprising same |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CU01 | Correction of utility model |
Correction item: Drawings Correct: Deleted text with figure 5-8 False: Figure 5-8 with text Number: 43 Page: Description Volume: 30 |
|
| RECT | Rectification | ||
| CP01 | Change in the name or title of a patent holder |
Address after: Singapore Singapore Patentee after: Bioengineering Co.,Ltd. Address before: Singapore Singapore Patentee before: CLEARBRIDGE BIOMEDICS Pte. Ltd. |
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| CP01 | Change in the name or title of a patent holder | ||
| CX01 | Expiry of patent term |
Granted publication date: 20141022 |
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| CX01 | Expiry of patent term |