CN203790303U - Fluid-bed granulator for drug preparation - Google Patents
Fluid-bed granulator for drug preparation Download PDFInfo
- Publication number
- CN203790303U CN203790303U CN201420171597.1U CN201420171597U CN203790303U CN 203790303 U CN203790303 U CN 203790303U CN 201420171597 U CN201420171597 U CN 201420171597U CN 203790303 U CN203790303 U CN 203790303U
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- air
- bed granulator
- cavity
- drying device
- fluid bed
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The utility model provides a fluid-bed granulator for drug preparation, relates to the technical field of drug preparation equipment, and mainly aims to solve the granule drying problem in the fluid-bed granulating process. The fluid-bed granulator comprises a granulating device and a drying device, wherein granules to be dried are conveyed to the drying device by the granulating device through a delivery pipe, and a cyclone separator for separating and collecting the granules blown out of the drying device is arranged between an air outlet of the drying device and an air inlet of the granulating device. The fluid-bed granulator has the benefits that air flow can be well dredged by an air distribution plate, so that the air flow and the drug granule fluidizing state can be more stable, and the drying process of the drug granules is effectively ensured; uniform heat flow can be effectively provided by an upper mesh plate and a lower mesh plate, and the drying process of the drug granules can be more stably and effectively ensured in the fluidizing state.
Description
Technical field
This utility model relates to pharmaceutical technology field, provides a kind of medicine for the preparation of medicine particle to prepare the fluid bed granulator of use.
Background technology
Fluid bed granulator is mainly used in medicine pelletize and coating, its cardinal principle is for to drop into granular material in hopper hermetic container, effect due to thermal current, making powder suspension be fluidisation shape circulates, reach even mixing, spray into the powder in vaporific binding agent wetting container simultaneously, make the powder loose granule that congeals into, in the time of granulating, because thermal current is made highly effective drying to it, moisture content constantly evaporates, powder constantly solidifies, drawing process repeats, form desirable, uniform many micropores spherical particle, in container, once complete mixing, pelletize, dry three operations.
General modern fluid bed granulator; all that steam provides the energy together with heat engine; using air as drying medium; and this fluid bed granulator adopts warm-air pipe to rouse hot blast in mixing granulation chamber; this hot gas source pressure transient traditionally; in mixing granulation chamber, be sometimes not easy to form good fluidized state, carried out negative effect necessarily to powder dry zone.
And existing fluid bed granulator need to provide clean hot-air when work; therefore at air inlet, air filter is all installed; because air filter cannot bear the high temperature air after heater heating; all air filters are all arranged on heater front end; and along with the increase of time, heater is because heated oxide easily produces black foreign material; black foreign material flow to the wind into mixing granulation chamber, thereby pollute medicine.
Utility model content
The purpose of this utility model is to improve a kind ofly can prepare medicine particle, and can carry out moistening medicine particle stable dryly, and in dry run, there will not be the fluid bed granulator because of heater impurity pollution medicine.
This utility model is to achieve these goals by the following technical solutions:
A kind of medicine is prepared the fluid bed granulator of use; comprise granulation device and drying device; granulation device is carried granule to be dried by feed pipe to drying device, is provided with for the granule blowing out from drying device being carried out to the cyclone separator of separated and collected between the air outlet of drying device and the air inlet of granulation device.The public air-blast device of this utility model granulation device and drying device, has saved motor consumption, thereby and can be by through the wind energy of drying device, to granulation device, utilization has reached the object of energy savings.Simultaneously granulation device air inlet is also provided with auxiliary air inlet, when the wind-force of sending here when drying device can not meet granulation device work requirements, can adopt auxiliary air inlet to carry out air blast.
In technique scheme, granulation device comprises cavity, and cavity bottom is provided with air inlet, cavity middle part is for mixing system material chamber, cavity top is provided with suction opeing, and air inlet is provided with cyclonic air flow distribution grid with mixing between system material chamber, mixes between system material chamber and suction opeing and being provided with filtration cloth bag.Being arranged so that of wind airflow-distribution board enters the wind that mixes system material chamber to mix system material indoor from eddy current state from air inlet, makes the medicine powder of processing can access sufficient fluidisation.
In technique scheme, filter cloth bag and fix by cloth bag bracket, and be provided with vibrating device on cloth bag bracket.
In technique scheme, mix system material chamber and be provided with for spraying the shower nozzle of atomized adhesive.
In technique scheme, drying device comprises dry cavity, dry cavity bottom is provided with air outlet, top is provided with air outlet, dry cavity middle part is hothouse, between hothouse and air outlet, be provided with airflow uniform distribution plate, airflow uniform distribution plate comprises lower net orifice plate, ventilation arm and the upper wire orifice plate setting gradually.Airflow uniform distribution plate can be good at dredging flow, makes the fluidized state of air-flow and powder can be more stable, effectively ensures the dry run of powder.Upper wire orifice plate and lower net orifice plate can effectively provide uniform hot-fluid, and fluidized state can the more steady dry run that effectively ensures powder.
The air outlet front end of drying device is disposed with flow stabilizing valve, pressure maintaining valve, air-valve and air filter, and air filter comprises rustless steel card clothing, heater, high efficiency particulate air filter and the roughing efficiency air filter setting gradually.The effect of pressure maintaining valve and flow stabilizing valve is pressure and the flow velocity of air-flow continually and steadily, and it coordinates airflow uniform distribution plate that uniform hot-fluid can be effectively provided, and fluidized state can the more steady dry run that effectively ensures powder.Rustless steel card clothing is arranged on the air outlet of drying device between heater, effectively solved the pollution problem that foreign material that heater produces cause.
In technique scheme, cyclone separator comprises whirlwind cavity, the inlet channel on top, in logical arm, in logical arm from whirlwind cavity top, be inserted into bottom, form inlet channel in the air duct of logical arm outlet, and air duct porch is provided with the oblique sheet of whirlwind.Working time wind energy enters after inlet channel, again after the oblique sheet of whirlwind, form whirlwind eddy current, the drug particles waving with whirlwind eddy current centrifugal from effect under hit the inwall of whirlwind cavity, then under the effect of gravity, drug particles glides along whirlwind cavity inner wall, falls into collection bucket, cyclone separator can effectively have been separated the granule being blown in drying device, has guaranteed to enter the cleaning of the wind before granulation device.
In technique scheme, the inclination angle of cyclonic air flow distribution grid is 45 ° can effectively produce eddy current in granulation device, makes medicine powder fluidized state better.When the inclination angle of the oblique sheet of described whirlwind is 45 °, can effectively produces eddy current, thereby drug particles is carried out to separation.
The beneficial effects of the utility model are: airflow uniform distribution plate can be good at dredging flow, make the fluidized state of air-flow and powder can be more stable, effectively ensure the dry run of powder.Upper wire orifice plate and lower net orifice plate can effectively provide uniform hot-fluid, and fluidized state can the more steady dry run that effectively ensures powder.Being arranged so that of wind airflow-distribution board enters the wind that mixes system material chamber to mix system material indoor from eddy current state from air inlet, makes the medicine powder of processing can access sufficient fluidisation.Airflow uniform distribution plate can be good at dredging flow, makes the fluidized state of air-flow and powder can be more stable, effectively ensures the dry run of powder.Upper wire orifice plate and lower net orifice plate can effectively provide uniform hot-fluid, and fluidized state can the more steady dry run that effectively ensures powder.Working time wind energy enters after inlet channel, again after the oblique sheet of whirlwind, form whirlwind eddy current, the drug particles waving with whirlwind eddy current centrifugal from effect under hit the inwall of whirlwind cavity, then under the effect of gravity, drug particles glides along whirlwind cavity inner wall, falls into collection bucket, cyclone separator can effectively have been separated the granule being blown in drying device, has guaranteed to enter the cleaning of the wind before granulation device.When the inclination angle of the oblique sheet of described whirlwind is 45 °, can effectively produces eddy current, thereby drug particles is carried out to separation.
Accompanying drawing explanation
Fig. 1 is the fluid bed granulator structural representation that a kind of medicine of this utility model is prepared use;
Fig. 2 is airflow uniform distribution plate structure schematic diagram of the present utility model;
Fig. 3 is the oblique chip architecture schematic diagram of whirlwind of the present utility model.
The specific embodiment
Below in conjunction with accompanying drawing 1,2 and 3 and specific embodiment fluid bed granulator that a kind of medicine of this utility model is prepared to use be further described.
The embodiment that a kind of medicine of this utility model is prepared the fluid bed granulator of use is not limited to following examples, within the various variations of making under the prerequisite that does not depart from this utility model aim all belong to protection domain of the present utility model.
This practical information provides a kind of medicine to prepare the fluid bed granulator of use; comprise granulation device and drying device; granulation device is carried granule to be dried by feed pipe 13 to drying device, and the air outlet 17 of drying device and 18 of the air inlets of granulation device are provided with for the granule blowing out from drying device being carried out to the cyclone separator 10 of separated and collected.The public air-blast device of this utility model granulation device and drying device, has saved motor consumption, thereby and can be by through the wind energy of drying device, to granulation device, utilization has reached the object of energy savings.Simultaneously granulation device air inlet 18 is also provided with auxiliary air inlet, when the wind-force of sending here when drying device can not meet granulation device work requirements, can adopt auxiliary air inlet to carry out air blast.
Embodiment 1
The fluid bed granulator that a kind of medicine is prepared use comprises granulation device and drying device; granulation device is carried granule to be dried by feed pipe 13 to drying device, and the air outlet 17 of drying device and 18 of the air inlets of granulation device are provided with for the granule blowing out from drying device being carried out to the cyclone separator 10 of separated and collected.
Granulation device comprises cavity 19, cavity 19 bottoms are provided with air inlet 18, cavity 19 middle parts are for mixing system material chamber 21, cavity 19 tops are provided with suction opeing 16, to be provided with inclination angle be the cyclonic air flow distribution grid 12 of 45 ° to air inlet 18 with mixing 21 of chambers of system material, mixes system material chamber 21 and be provided with filtration cloth bag 14 with 16 of suction opeings.
Filter cloth bag 14 fixing by cloth bag bracket 22, and on cloth bag bracket 22, be provided with vibrating device 15.Mixing system material chamber 21 is provided with for spraying the shower nozzle 23 of atomized adhesive.
Drying device comprises dry cavity 24, dry cavity bottom is provided with air outlet 25, top is provided with air outlet 17, dry cavity 24 middle parts are hothouse 27,25 of hothouse 27 and air outlets are provided with airflow uniform distribution plate 9, and airflow uniform distribution plate 9 comprises lower net orifice plate 91, ventilation arm 92 and the upper wire orifice plate 93 setting gradually.
Air outlet 25 front ends of drying device are disposed with flow stabilizing valve 8, pressure maintaining valve 7, air-valve 6 and air filter, and air filter comprises rustless steel card clothing 5, heater 4, high efficiency particulate air filter 3 and the roughing efficiency air filter 2 setting gradually.
Cyclone separator comprises whirlwind cavity 102, the inlet channel 104 on top, in logical arm 101, in logical arm 101 from whirlwind cavity 102 tops, be inserted into bottom, form inlet channel 104 in the air duct of logical arm 101 outlets, and to be provided with inclination angle be the oblique sheet 103 of whirlwind of 45 ° in air duct porch.
During work, open air blast pump 1, air enters primary filter, mainly filters out the above dust particle of 5 μ m, then passes through high efficiency particulate air filter, particle dust and various float below trapping 0.5um.Then by the air after filtering, give heater heating, heater as produced impurity in life-time service, impurity filters out by rustless steel card clothing 5, finally obtain clean hot blast, clean heat is divided through air-valve 6, then after the effect of pressure maintaining valve and flow stabilizing valve, obtain pressure and the continual and steady air-flow of flow velocity, then give drying device, airflow uniform distribution plate 9 through drying device can be good at dredging flow, make the fluidized state of air-flow and powder can be more stable, effectively ensure the dry run of powder.Upper wire orifice plate and lower net orifice plate can effectively provide uniform hot-fluid, and fluidized state can the more steady dry run that effectively ensures powder.Granule is carried out to dried gas to be sent by the air outlet 17 on the top of drying device, air outlet 17 can be taken some drugs granule out of, therefore air outlet 17 is connected to cyclone separator, working time wind energy enters after inlet channel, again after the oblique sheet 103 of whirlwind, form whirlwind eddy current, the drug particles waving with whirlwind eddy current centrifugal from effect under hit the inwall of whirlwind cavity, then under the effect of gravity, drug particles glides along whirlwind cavity inner wall, fall into collection bucket 11, cyclone separator can effectively have been separated the granule being blown in drying device, guaranteed to enter the cleaning of the wind before granulation device.Wind energy then enters granulation device, after cyclonic air flow distribution grid, gas under the effect of the wind airflow-distribution board 12 of granulation device, make to enter from air inlet mix system material chamber 21 wind within mixing system material chamber 21 from eddy current state, make the medicine powder of processing can access sufficient fluidisation.The binding agent of shower nozzle 23 ejection atomizations simultaneously, material is mixed fully, under the effect of air exhauster, drug dust is captured at filtration cloth bag, when becomeing trapped in, drug powder opens vibrating device a certain amount of time, the powder filtering on cloth bag is shaken off, so repeated, know and granulated.
The beneficial effect of the present embodiment 1 is: airflow uniform distribution plate can be good at dredging flow, makes the fluidized state of air-flow and powder can be more stable, effectively ensures the dry run of powder.Upper wire orifice plate and lower net orifice plate can effectively provide uniform hot-fluid, and fluidized state can the more steady dry run that effectively ensures powder.Being arranged so that of wind airflow-distribution board enters the wind that mixes system material chamber to mix system material indoor from eddy current state from air inlet, makes the medicine powder of processing can access sufficient fluidisation.Airflow uniform distribution plate can be good at dredging flow, makes the fluidized state of air-flow and powder can be more stable, effectively ensures the dry run of powder.Upper wire orifice plate and lower net orifice plate can effectively provide uniform hot-fluid, and fluidized state can the more steady dry run that effectively ensures powder.Working time wind energy enters after inlet channel, again after the oblique sheet of whirlwind, form whirlwind eddy current, the drug particles waving with whirlwind eddy current centrifugal from effect under hit the inwall of whirlwind cavity, then under the effect of gravity, drug particles glides along whirlwind cavity inner wall, falls into collection bucket, cyclone separator can effectively have been separated the granule being blown in drying device, has guaranteed to enter the cleaning of the wind before granulation device.When the inclination angle of the oblique sheet of described whirlwind is 45 °, can effectively produces eddy current, thereby drug particles is carried out to separation.
The fluid bed granulator that a kind of medicine of this utility model is prepared use is not limited to the aforesaid specific embodiment.This utility model expands to any new feature or any new combination disclosing in this manual, and the arbitrary new method disclosing or step or any new combination of process.
Claims (8)
1. a medicine is prepared the fluid bed granulator of use; it is characterized in that: comprise granulation device and drying device; granulation device is carried granule to be dried by feed pipe (13) to drying device, between the air inlet (18) of the air outlet of drying device (17) and granulation device, is provided with cyclone separator (10).
2. a kind of medicine according to claim 1 is prepared the fluid bed granulator of use; it is characterized in that: granulation device comprises cavity (19); cavity (19) bottom is provided with air inlet (18); cavity (19) middle part is for mixing system material chamber (21); cavity (19) top is provided with suction opeing (16); air inlet (18) is provided with cyclonic air flow distribution grid (12) with mixing between system material chamber (21), mixes between system material chamber (21) and suction opeing (16) and being provided with filtration cloth bag (14).
3. a kind of medicine according to claim 2 is prepared the fluid bed granulator of use, it is characterized in that: filter cloth bag (14) fixing by cloth bag bracket (22), and on cloth bag bracket (22), be provided with vibrating device (15).
4. a kind of medicine according to claim 2 is prepared the fluid bed granulator of use, it is characterized in that: mix system material chamber (21) and be provided with shower nozzle (23).
5. a kind of medicine according to claim 1 is prepared the fluid bed granulator of use; it is characterized in that: drying device comprises dry cavity (24); dry cavity bottom is provided with air outlet (25); top is provided with air outlet (17); dry cavity (24) middle part is hothouse (27); between hothouse (27) and air outlet (25), be provided with airflow uniform distribution plate (9), airflow uniform distribution plate (9) comprises lower net orifice plate (91), ventilation arm (92) and the upper wire orifice plate (93) setting gradually.
6. a kind of medicine according to claim 1 is prepared the fluid bed granulator of use; it is characterized in that: the air outlet of drying device (25) front end is disposed with flow stabilizing valve (8), pressure maintaining valve (7), air-valve (6) and air filter, air filter comprises rustless steel card clothing (5), heater (4), high efficiency particulate air filter (3) and the roughing efficiency air filter (2) setting gradually.
7. a kind of medicine according to claim 1 is prepared the fluid bed granulator of use; it is characterized in that: cyclone separator comprises whirlwind cavity (102); the inlet channel on top (104); in logical arm (101); in logical arm (101) from whirlwind cavity (102) top, be inserted into bottom; form inlet channel (104) in the air duct of logical arm (101) outlet, and air duct porch is provided with the oblique sheet of whirlwind (103).
8. according to the arbitrary described a kind of medicine of claim 7 or 2, prepare the fluid bed granulator of use, it is characterized in that: the inclination angle of the oblique sheet of described whirlwind (103) and cyclonic air flow distribution grid (12) is 45 °.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420171597.1U CN203790303U (en) | 2014-04-10 | 2014-04-10 | Fluid-bed granulator for drug preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420171597.1U CN203790303U (en) | 2014-04-10 | 2014-04-10 | Fluid-bed granulator for drug preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203790303U true CN203790303U (en) | 2014-08-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420171597.1U Expired - Fee Related CN203790303U (en) | 2014-04-10 | 2014-04-10 | Fluid-bed granulator for drug preparation |
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| Country | Link |
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| CN (1) | CN203790303U (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104181857A (en) * | 2014-09-11 | 2014-12-03 | 四川科伦药业股份有限公司 | Material leakage linkage control system of fluid bed granulating drier |
| CN104707536A (en) * | 2015-03-16 | 2015-06-17 | 翰林航宇（天津）实业有限公司 | Wet mixing pelletizer internally provided with granulator |
| CN105640775A (en) * | 2016-02-28 | 2016-06-08 | 徐海慧 | Diverse feeding device for producing tablets in batches |
| CN113876585A (en) * | 2021-09-30 | 2022-01-04 | 浙江亚峰药厂有限公司 | Preparation system and process of pediatric paracetamol, atificial cow-bezoar and chlorphenamine maleate granules |
| CN116428843A (en) * | 2023-05-29 | 2023-07-14 | 中国海洋大学 | Quick drying device of brine shrimp ovum |
-
2014
- 2014-04-10 CN CN201420171597.1U patent/CN203790303U/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104181857A (en) * | 2014-09-11 | 2014-12-03 | 四川科伦药业股份有限公司 | Material leakage linkage control system of fluid bed granulating drier |
| CN104181857B (en) * | 2014-09-11 | 2017-12-15 | 四川科伦药业股份有限公司 | A kind of Fluidbedgranulatingdrier material from leakage coordinated control system |
| CN104707536A (en) * | 2015-03-16 | 2015-06-17 | 翰林航宇（天津）实业有限公司 | Wet mixing pelletizer internally provided with granulator |
| CN105640775A (en) * | 2016-02-28 | 2016-06-08 | 徐海慧 | Diverse feeding device for producing tablets in batches |
| CN105640775B (en) * | 2016-02-28 | 2022-03-18 | 青海制药有限公司 | Various feeding device for batch production of medicine granules |
| CN113876585A (en) * | 2021-09-30 | 2022-01-04 | 浙江亚峰药厂有限公司 | Preparation system and process of pediatric paracetamol, atificial cow-bezoar and chlorphenamine maleate granules |
| CN116428843A (en) * | 2023-05-29 | 2023-07-14 | 中国海洋大学 | Quick drying device of brine shrimp ovum |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140827 Termination date: 20150410 |
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| EXPY | Termination of patent right or utility model |