CN203786006U - Flow cytometry laser integration device - Google Patents
Flow cytometry laser integration device Download PDFInfo
- Publication number
- CN203786006U CN203786006U CN201420167117.4U CN201420167117U CN203786006U CN 203786006 U CN203786006 U CN 203786006U CN 201420167117 U CN201420167117 U CN 201420167117U CN 203786006 U CN203786006 U CN 203786006U
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- laser
- fiber coupler
- flow cytometry
- laser instrument
- flow cytometer
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- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The utility model discloses a flow cytometry laser integration device which comprises a laser radiation unit as well as an optical fiber coupler, a beam shaping unit and a flowing detection pool which are sequentially arranged along the laser transmission direction. The device has the beneficial effects that by a plurality of laser optical fiber coupling devices, the system structure is easy to adjust, the interference resistance is high, errors caused by laser wavelength shifting can be prevented, and the structure is modularized and is applicable to packaging and production.
Description
Technical field
The utility model relates to technical field of medical instruments, is specially a kind of flow cytometer laser integrating apparatus.
Background technology
Flow cytometer is the advanced science and technology equipment that the multi-door subject technologies such as light harvesting, electronics, fluid mechanics, cytochemistry, biology, immunology and laser and computing machine are integrated, and it is widely used in the fields such as clinical medicine, cytology, biology, microbiology, pharmaceutics, genesiology.Be one of advanced instrument in modern scientific research, be described as " CT " in laboratory.It to the single-row cell in quick streamlined flow state or biologic grain carry out one by one, the technology of multiparameter, qualitative and quantitative analysis or sorting fast, there is the features such as detection speed is fast, measurement parameter is many, image data is large, analysis is comprehensive, separating purity is high, method is flexible.
Existing flow cytometer laser beam integration system is to utilize to close transmission that light microscopic realizes different optical maser wavelengths and the integration of having reflected different wave length laser.Therefore, it is high that existing laser beam merging system has the accuracy requirement of putting, and adjusts difficulty, and structure is dumb, is unfavorable for the modularization of system and is easily subject to the shortcomings such as interference of outside noise.
Utility model content
The purpose of this utility model is to provide a kind of structure that had both been easy to adjust in order to overcome above-mentioned deficiency, has again compared with strong anti-interference ability, prevents the flow cytometer laser integrating apparatus of the error that causes due to laser wavelength drift.
For solving the problems of the technologies described above, realize above-mentioned purpose, the utility model is achieved through the following technical solutions:
A flow cytometer laser integrating apparatus, comprises laser emission unit and flow detection pond, between described laser emission unit and flow detection pond, along laser propagation direction, is docile and obedient inferior be provided with fiber coupler and beam shaping unit.
Further, described laser emission unit comprises at least two parallel placement laser instruments.
Preferably, described fiber coupler comprises at least two input ends and an output terminal, and the number of described input end is identical with the number of laser instrument, described each laser instrument and the coaxial setting respectively of each input end.
Further, described beam shaping unit is by perpendicular to optical axis direction and be docile and obedient time the collimation lens, the first cylindrical mirror, the second cylindrical mirror and the condenser lens that arrange and form.
The utlity model has following beneficial effect:
Adopt coupling device for multiple bunches of laser fiber, make system architecture be easy to adjust, antijamming capability is strong, can prevent the error that causes due to laser wavelength drift, structural module, is applicable to encapsulation, is convenient to produce.
Accompanying drawing explanation
Fig. 1 is fiber coupler schematic diagram
Fig. 2 is laser integration system schematic diagram.
Embodiment
Below in conjunction with drawings and Examples, further illustrate the utility model.
A kind of flow cytometer laser integrating apparatus as shown in Figure 2, comprises laser radiation unit 100, optical fiber coupling device 200, beam shaping unit 300 and flow detection pond 400.Wherein laser emission unit 100 includes a plurality of parallel compact laser instruments 101 of placing, and what in laser emission unit 100, along laser propagation direction, arrange is fiber coupler 200.As shown in Figure 1, optical fiber coupling device 200 includes a plurality of input ends 201, an and output terminal 202, the input end 201 of optical fiber coupling device 200 and laser instrument 101 concentric placement one to one, and keep suitable distance, with guarantee laser beam can with the coupled lens quadrature of input end 201, make laser beam can be coupled into the input end 201 of fiber coupler 200.And by total reflection, transmit and arrive output terminal 202 in optical fiber, the output that realizes multiple laser becomes the output of beam of laser.Be positioned at fiber coupler 200 rears, along direction of beam propagation, it is beam shaping unit 300, it is comprised of collimation lens 301, the first cylindrical mirror 302, the second cylindrical mirror 303 and condenser lens 304, collimation lens 301 is placed in fiber coupler 200 output terminal 202 rears, and perpendicular to optical axis direction, the light of optical fiber coupling device 200 output terminal 202 outputs is collimated into directional light.The first cylindrical mirror 302 different with the second cylindrical mirror 303 curvature and mutually vertical collimation lens 301 rears that are positioned over along optical axis direction, to guarantee light vertical incidence, the first cylindrical mirror 302 and the second cylindrical mirror 303 are mainly used in light beam X-axis and Y direction to carry out compression in various degree, form fluidic cell and detect required oval hot spot.The plano-convex circle lens that place along optical axis direction at the second cylindrical mirror 303 rears is as condenser lens 304, and the optimal spot that forms applicable cell detection for light beam is further compressed exposes to the cell sample stream in flow detection pond 400.
Above-described embodiment is preferably embodiment of the utility model; but embodiment of the present utility model is not restricted to the described embodiments; other any do not deviate from change, the modification done under Spirit Essence of the present utility model and principle, substitutes, combination, simplify; all should be equivalent substitute mode, within being included in protection domain of the present utility model.
Claims (3)
1. a flow cytometer laser integrating apparatus, comprise a plurality of laser instrument (101) and flow detection pond (400) that are parallel to each other and place, it is characterized in that along laser propagation direction, being docile and obedient the inferior fiber coupler (200) that is provided with between described laser instrument (101) and flow detection pond (400), collimation lens (301), the first cylindrical mirror (302), the second cylindrical mirror (303) and condenser lens (304), described fiber coupler (200) comprises at least two input ends (201) and an output terminal (202), the number of described input end (201) is identical with the number of laser instrument (101), described each laser instrument (101) coaxially arranges respectively with each input end (201).
2. flow cytometer laser integrating apparatus according to claim 1, the number that it is characterized in that described laser instrument (101) is two.
3. flow cytometer laser integrating apparatus according to claim 1 and 2, is characterized in that described fiber coupler (200) comprises two input ends (201).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420167117.4U CN203786006U (en) | 2014-04-09 | 2014-04-09 | Flow cytometry laser integration device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420167117.4U CN203786006U (en) | 2014-04-09 | 2014-04-09 | Flow cytometry laser integration device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203786006U true CN203786006U (en) | 2014-08-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420167117.4U Expired - Fee Related CN203786006U (en) | 2014-04-09 | 2014-04-09 | Flow cytometry laser integration device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203786006U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106226224A (en) * | 2016-08-18 | 2016-12-14 | 重庆玖润隆科技有限公司 | A kind of particle analyzer optical system |
-
2014
- 2014-04-09 CN CN201420167117.4U patent/CN203786006U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106226224A (en) * | 2016-08-18 | 2016-12-14 | 重庆玖润隆科技有限公司 | A kind of particle analyzer optical system |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140820 Termination date: 20150409 |
|
| EXPY | Termination of patent right or utility model |