CN203724206U - Cold and hot knife with drug conveying function and system - Google Patents
Cold and hot knife with drug conveying function and system Download PDFInfo
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- CN203724206U CN203724206U CN201420074065.6U CN201420074065U CN203724206U CN 203724206 U CN203724206 U CN 203724206U CN 201420074065 U CN201420074065 U CN 201420074065U CN 203724206 U CN203724206 U CN 203724206U
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- medicine
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- introducing pipe
- hot cutter
- drug delivery
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Abstract
The utility model provides a cold and hot knife with a drug conveying function and a system. The cold and hot knife comprises a cold and hot knife body, a drug guide tube and an injection unit, one end of the drug guide tube is open while the other end of the same is closed, drug outgoing holes are arranged on the bottom wall and/or the side wall of the drug guide tube, the injection unit is connected with the open end of the drug guide tube, a drug guide tube passage is arranged on the cold and hot knife body, and the drug guide tube is positioned in the drug guide tube passage. On the basis of structure of a conventional cold and hot knife, the drug guide tube capable of conveying drugs is added, so that the cold and hot knife is enabled to be capable of completing cold and hot treatment and can complete conveying of antitumor drugs, treatment effect of the cold and hot knife is improved, application range of the cold and hot knife is widened, and the cold and hot knife is enabled to have better treatment effect on tumors small in diameter and regular in shape and be suitable for treating tumors large in diameter and irregular in shape.
Description
Technical field
This utility model relates to medical instruments field, particularly a kind of cold and hot cutter and system with drug delivery capabilities.
Background technology
Tumor be body under various carcinogenic factor effects, some cells of local organization lose the normal regulation to its growth on gene level, cause its clonal abnormality hypertrophy and the abnormality that forms, generally tumor are divided into the optimum and large class of malignant tumor two.Tumor is to threaten human life and healthy a kind of common disease, and in recent years, the M & M of the cancer that the whole world is caused by tumor is the trend rising year by year, the primary enemy who has leapt to whole world human life's health.
Along with scientific and technical development, the method for the treatment of tumor has a variety of, as tumor operation treatment, chemotherapy of tumors, tumor radiotherapy etc.Conventionally early stage patient can pass through excision, but because cancerous cell and uncontrollable transfer usually cannot be thoroughly removed in operation, therefore operative treatment tumor may after the several years, exist can recurrence and metastatic potential, and traditional operation treatment also exist wound large, hemorrhage many, patient recovers slowly, the hospital stays grow etc. shortcoming.Chemotherapy of tumors is to kill tumor tissues by chemotherapeutics, reaches therapeutic effect, and because chemotherapy is usually systemic administration, chemotherapeutics also has certain injury to human normal cell conventionally, and particularly weakly patient should not adopt embolic chemotherapy.Radiotherapy is to kill tumor tissues by high-energy rays, relatively be applicable to the epidermis cancers such as treatment skin, scale cancer, for human viscera organ's cancer DeGrain, and also can cause very major injury by normal tissue, radiation and chemotherapy is in killing and wounding cancerous cell simultaneously, also will together kill normal cell and immunity (opposing) cell, be prone to toxic and side effects.Therefore not only success rate is not high for traditional remedies, and has a strong impact on patient's orthobiosis, most people's disability.
For better and safer treat tumor, cold and hot cutter technology has obtained development fast in recent years.Cold and hot cutter is a kind of emerging medical apparatus and instruments that is used for the treatment of tumor, and it can be implemented that fast cooling freezes and suddenly heat up tumor tissues, thus destroyed tumor tissue effectively.But existing cold and hot cutter is only applicable to treat the tumor of diameter little (refer generally to diameter and be less than 4cm) and regular shape, for diameter, larger or tumor in irregular shape is difficult to all kill, and tends to like this cause postoperative easy recurrence.
Utility model content
The technical problems to be solved in the utility model is to provide a kind of tumor that is not only applicable to treat the little and regular shape of diameter, and to diameter, large and tumor in irregular shape also can play the cold and hot cutter with drug delivery capabilities and the cold and hot cutter system of good therapeutic effect.
For solving the problems of the technologies described above, this utility model provides a kind of cold and hot cutter with drug delivery capabilities, comprises cold and hot cutter main body, medicine-introducing pipe and injecting unit; One end opening of described medicine-introducing pipe, other end sealing, is provided with medicine outlet hole on the diapire of described medicine-introducing pipe and/or sidewall, and described injecting unit is connected with one end of described medicine-introducing pipe opening; In described cold and hot cutter main body, be provided with medicine-introducing pipe passage, described medicine-introducing pipe is arranged in described medicine-introducing pipe passage.
Preferably, the diameter of described medicine-introducing pipe is 0.5mm～1.0mm.
Preferably, described medicine-introducing pipe passage is positioned on the knife bar of described cold and hot cutter main body.
More preferably, the diameter of described medicine-introducing pipe is 1/10～1/5 of described knife bar diameter.
More preferably, described medicine-introducing pipe passage is the groove on described knife bar outer surface.
More preferably, the cross sectional shape of described groove is the circular arc that is greater than 1/2 circumference, and the diameter of described medicine-introducing pipe passage is than the large 0.01mm～0.05mm of the diameter of described medicine-introducing pipe.
Preferably, described injecting unit is syringe pump.
This utility model also provides a kind of cold and hot cutter system, comprises above-mentioned cold and hot cutter, information acquisition unit, medicine-introducing pipe mobile control unit and control unit with drug delivery capabilities; The tumor information that described control unit collects according to described information acquisition unit, output medicine-introducing pipe rate travel signal and injection rate signal; Described injecting unit is according to the output speed of injection rate signal controlling medicine, and described medicine-introducing pipe mobile control unit is according to the rate travel of medicine-introducing pipe in described medicine-introducing pipe passage described in medicine-introducing pipe rate travel signal controlling.
Preferably, described information acquisition unit is nuclear magnetic resonance analyser.
Preferably, described medicine-introducing pipe mobile control unit is micro machine.
The cold and hot cutter with drug delivery capabilities that this utility model provides has increased medicine-introducing pipe that can delivering medicament on the architecture basics of the cold and hot cutter of tradition, make cold and hot cutter in can completing cold and hot treatment, can also complete the conveying of antitumor drug, therapeutic effect and the scope of application of cold and hot cutter are improved, make cold and hot cutter not only tumor little to diameter and regular shape have therapeutic effect better, and be applicable to treat the large and tumor in irregular shape of diameter.
The cold and hot cutter system that this utility model provides is by the control to injecting unit and medicine-introducing pipe mobile control unit, can ensure that antitumor drug is penetrated in tumor tissues more uniformly, thereby tumor is played to better therapeutic effect, and be easy to realize full-automation, be convenient to promoting the use of of cold and hot cutter system.
Brief description of the drawings
Fig. 1 is the structural representation of the cold and hot cutter embodiment of this utility model band drug delivery capabilities;
Fig. 2 is the structural representation of the medicine-introducing pipe embodiment of the cold and hot cutter of this utility model band drug delivery capabilities;
Fig. 3 is the signal transmission schematic diagram of the cold and hot cutter system embodiment of this utility model.
In figure, indicate as follows:
With cold and hot cutter-1 of drug delivery capabilities, cold and hot cutter main body-11, handle of a knife-11a, knife bar-11b, cutter head-11c, medicine-introducing pipe passage-110, medicine-introducing pipe-12, medicine outlet hole-120, injecting unit-13, information acquisition unit-2, medicine-introducing pipe mobile control unit-3, control unit-4.
Detailed description of the invention
For the above-mentioned purpose, the feature and advantage that make utility model can become apparent more, below detailed description of the invention of the present utility model is described in detail.
A lot of details are set forth in the following description so that fully understand this utility model, but this utility model can also adopt other to be different from alternate manner described here and implement, those skilled in the art can do similar popularization without prejudice to this utility model intension in the situation that, and therefore this utility model is not subject to the restriction of following public specific embodiment.
As depicted in figs. 1 and 2, comprise cold and hot cutter main body 11, medicine-introducing pipe 12 and injecting unit 13 with the cold and hot cutter 1 of drug delivery capabilities, wherein cold and hot cutter main body 11 forms by connecting successively ground handle of a knife 11a, knife bar 11b and cutter head 11c; One end opening of described medicine-introducing pipe 12, other end sealing, on the diapire of described medicine-introducing pipe 12 and/or sidewall, be provided with medicine outlet hole 120, described injecting unit 13 is connected with one end of described medicine-introducing pipe 12 openings, above-mentioned diapire refers to the wall that the face of one end that medicine-introducing pipe 12 seals forms, sidewall refers to the wall that medicine-introducing pipe 12 sides form, and injecting unit 13 is by antitumor drug after one end of medicine-introducing pipe 12 openings is injected, and antitumor drug is exported from medicine outlet hole 120 again; In described cold and hot cutter main body 11, be provided with medicine-introducing pipe passage 110; described medicine-introducing pipe 12 is arranged in described medicine-introducing pipe passage 110; medicine-introducing pipe passage 110 makes the antitumor drug that medicine-introducing pipe 12 is exported can enter tumor tissues with extraneous communicating; the more important thing is the effect of playing protection medicine-introducing pipe 12, thereby extend the service life of medicine-introducing pipe 12.
Wherein, on medicine-introducing pipe 12, the quantity of medicine outlet hole 120 and size are according to real needs setting, and this utility model does not further limit this, on the diapire of medicine-introducing pipe 12 and sidewall, can be provided with medicine outlet hole 120 simultaneously, also can only be positioned on diapire or sidewall.
In the operating process of above-mentioned cold and hot cutter 1 embodiment with drug delivery capabilities, medicine-introducing pipe 12 is along with cold and hot cutter main body 11 enters tumor tissues together, injecting unit 13 injects antitumor drug from one end of medicine-introducing pipe 12 openings, antitumor drug is exported from the medicine outlet hole 120 of medicine-introducing pipe 12 again, enter tumor tissues by medicine-introducing pipe passage 110 with the place of communicating of the external world, at this moment carry out again the cold and hot treatment of cold and hot cutter.The setting of the medicine outlet hole 120 on medicine-introducing pipe 12 not only can reduce the flow resistance of medicine in medicine-introducing pipe 12 effectively, and is conducive to make antitumor drug more evenly to enter rapidly tumor tissues.The time of delivery of antitumor drug can be before cold and hot treatment or after cold and hot treatment or in cold and hot treatment, and preferably, in cold and hot treatment, Drug therapy and cold and hot treatment are carried out simultaneously like this, can play oncotherapy effect better.
The diameter of the disclosed medicine-introducing pipe 12 of this utility model preferably can be 0.5mm～1.0mm, to facilitate, medicine outlet hole 120 is set on medicine-introducing pipe 12.
It should be noted that, the concrete setting position of medicine-introducing pipe passage 110 arranges according to the actual requirements, and certainly in order to facilitate the formation of medicine-introducing pipe passage 110, described medicine-introducing pipe passage 110 is positioned on the knife bar 11b of described cold and hot cutter main body 11.For the ease of medicine-introducing pipe 12 being assemblied in the medicine-introducing pipe passage 110 of cold and hot cutter main body 11, the diameter of described medicine-introducing pipe 12 be preferably described cold and hot cutter main body 11 knife bar 11b diameter 1/10～1/5.
To those skilled in the art, the concrete shape of medicine-introducing pipe passage 110 and size have multiple implementation according to the actual requirements, if medicine-introducing pipe passage 110 is through hole, it is the hole of the medicine-introducing pipe passage 110 upper both ends open of knife bar 11b that is cold and hot cutter main body 11, medicine-introducing pipe 12 is arranged in above-mentioned hole, more preferably also can adopt following detailed description of the invention: described medicine-introducing pipe passage 110 is the groove on described knife bar 11b outer surface, more preferably, the cross sectional shape of described groove is the circular arc that is greater than 1/2 circumference, and the diameter of described medicine-introducing pipe passage 110 is than the large 0.01mm～0.05mm of the diameter of described medicine-introducing pipe 12, medicine-introducing pipe passage 110 is ensureing under the prerequisite of medicine-introducing pipe 12 smooth movements like this, can play coating function to medicine-introducing pipe 12, thereby effectively prevent that medicine-introducing pipe 12 from sustaining damage with tissue collision in the process of knife bar 11b insertion human body, and after antitumor drug exports in medicine-introducing pipe 12, enter tumor tissues by the opening part of medicine-introducing pipe passage 110 again, increase the contact area of antitumor drug and tumor tissues, make antitumor drug more promptly enter into tumor tissues.
Injecting unit 13 can adopt the conventional device in this area, preferably, described injecting unit 13 is for realizing the syringe pump of automatization, at one particularly in embodiment, in order more easily injecting unit 13 to be connected with medicine-introducing pipe 12, between injecting unit 13 and one end of medicine-introducing pipe 12 openings, be connected by conduit.
This utility model also provides a kind of cold and hot cutter system, and it comprises above-mentioned cold and hot cutter 1, information acquisition unit 2, medicine-introducing pipe mobile control unit 3 and control unit 4 with drug delivery capabilities; The tumor information that described control unit 4 collects according to described information acquisition unit 2, output medicine-introducing pipe rate travel signal and injection rate signal; Described injecting unit 13 is according to the output speed of injection rate signal controlling medicine, and described medicine-introducing pipe mobile control unit 3 is according to the rate travel of medicine-introducing pipe 12 in described medicine-introducing pipe passage 110 described in medicine-introducing pipe rate travel signal controlling.
Medicine-introducing pipe mobile control unit 3 is controlled the movement of medicine-introducing pipe 12 in described medicine-introducing pipe passage 110, medicine-introducing pipe 12 can be moved towards the direction of cold and hot cutter main body 11 cutter head 11c in medicine-introducing pipe passage 110, or towards the direction motion away from cold and hot cutter main body 11 cutter head 11c, the concrete direction of motion is selected according to the actual requirements.
In the embodiment of above-mentioned cold and hot cutter system, cold and hot cutter 1 with drug delivery capabilities inserts tumor tissues inside, information acquisition unit 2 gathers tumor information, and send tumor information to control unit 4, the tumor information that control unit 4 collects according to information acquisition unit 2, output medicine-introducing pipe rate travel signal and injection rate signal, injecting unit 13 receives the output speed of controlling medicine after injection rate signal, simultaneously medicine-introducing pipe mobile control unit 3 receives the rate travel of controlling medicine-introducing pipe 12 after medicine-introducing pipe rate travel signal, preferably medicine-introducing pipe 12 can be selected evenly to the direction motion away from cold and hot cutter main body 11 cutter head 11c, to protect better medicine-introducing pipe 12, so, completed rationally and the effectively process of delivering medicament of cold and hot cutter system.The signal transmission schematic diagram of cold and hot cutter system embodiment particularly as shown in Figure 3.
To those skilled in the art, the implementation of control unit 4 can be a central processing unit, the tumor information that control unit 4 collects according to information acquisition unit 2, the process of output medicine-introducing pipe rate travel signal and injection rate signal does not have concrete restriction, can adopt the conventional mode in this area, also can realize by following manner: the shape that tumor information is tumor and positional information, search data base according to the related data of tumor information and draw medicine-introducing pipe rate travel and injection rate, this data base is the data base of relation between the tumor information that draws according to clinical practice experience and medicine-introducing pipe rate travel and injection rate, certainly in order to draw more preferably medicine-introducing pipe rate travel and injection rate, tumor is produced to therapeutic effect better, in above-mentioned tumor information, also can comprise the relevant information such as the type of tumor and/or the period of tumor, or realize by following manner: the shape information that tumor information is tumor, control unit 4 collects minimum of Information generation of tumor according to information acquisition unit 2 and can surround ellipsoid or the ball of tumor tissues, and control unit 4 is tabled look-up or calculates medicine-introducing pipe rate travel and injection rate according to the radius data of the equatorial radius of ellipsoid and polar radius data or ball.
Because the dosage in therapeutic process is determined jointly by drug injection speed and medicine-introducing pipe rate travel, therefore be conducive to reduce antitumor drug and be penetrated into the amount in normal tissue cell, reduce the damage of the normal tissue cell of antitumor drug to tumor periphery, and ensure that antitumor drug is penetrated in tumor tissues uniformly.
The implementation of information acquisition unit 2 and medicine-introducing pipe mobile control unit 2 can have multiple, preferably, information acquisition unit 2 is nuclear magnetic resonance analyser, medicine-introducing pipe mobile control unit 3 is micro machine, and medicine-introducing pipe mobile control unit 3 can be set directly on the outer wall of medicine-introducing pipe 12, or in the handle of a knife 11a of cold and hot cutter main body 11.
Although this utility model is described in conjunction with above embodiment, but this utility model is not defined to above-described embodiment, and be only subject to the restriction of claims, those of ordinary skill in the art can easily modify to it and change, but do not leave essence design of the present utility model and scope.
Claims (10)
1. the cold and hot cutter with drug delivery capabilities, is characterized in that, comprises cold and hot cutter main body, medicine-introducing pipe and injecting unit; One end opening of described medicine-introducing pipe, other end sealing, is provided with medicine outlet hole on the diapire of described medicine-introducing pipe and/or sidewall, and described injecting unit is connected with one end of described medicine-introducing pipe opening; In described cold and hot cutter main body, be provided with medicine-introducing pipe passage, described medicine-introducing pipe is arranged in described medicine-introducing pipe passage.
2. the cold and hot cutter with drug delivery capabilities according to claim 1, is characterized in that, the diameter of described medicine-introducing pipe is 0.5mm～1.0mm.
3. the cold and hot cutter with drug delivery capabilities according to claim 1, is characterized in that, described medicine-introducing pipe passage is positioned on the knife bar of described cold and hot cutter main body.
4. the cold and hot cutter with drug delivery capabilities according to claim 3, is characterized in that, the diameter of described medicine-introducing pipe is 1/10～1/5 of described knife bar diameter.
5. the cold and hot cutter with drug delivery capabilities according to claim 3, is characterized in that, described medicine-introducing pipe passage is the groove on described knife bar outer surface.
6. the cold and hot cutter with drug delivery capabilities according to claim 5, is characterized in that, the cross sectional shape of described groove is the circular arc that is greater than 1/2 circumference, and the diameter of described medicine-introducing pipe passage is than the large 0.01mm～0.05mm of the diameter of described medicine-introducing pipe.
7. the cold and hot cutter with drug delivery capabilities according to claim 1, is characterized in that, described injecting unit is syringe pump.
8. a cold and hot cutter system, is characterized in that, comprises the cold and hot cutter with drug delivery capabilities, information acquisition unit, medicine-introducing pipe mobile control unit and the control unit described in claim 1 to 7 any one; The tumor information that described control unit collects according to described information acquisition unit, output medicine-introducing pipe rate travel signal and injection rate signal; Described injecting unit is according to the output speed of injection rate signal controlling medicine, and described medicine-introducing pipe mobile control unit is according to the rate travel of medicine-introducing pipe in described medicine-introducing pipe passage described in medicine-introducing pipe rate travel signal controlling.
9. cold and hot cutter system according to claim 8, is characterized in that, described information acquisition unit is nuclear magnetic resonance analyser.
10. cold and hot cutter system according to claim 8, is characterized in that, described medicine-introducing pipe mobile control unit is micro machine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420074065.6U CN203724206U (en) | 2014-02-20 | 2014-02-20 | Cold and hot knife with drug conveying function and system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420074065.6U CN203724206U (en) | 2014-02-20 | 2014-02-20 | Cold and hot knife with drug conveying function and system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203724206U true CN203724206U (en) | 2014-07-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420074065.6U Withdrawn - After Issue CN203724206U (en) | 2014-02-20 | 2014-02-20 | Cold and hot knife with drug conveying function and system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203724206U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103767783A (en) * | 2014-02-20 | 2014-05-07 | 中国科学技术大学 | Freezing and heating knife with medicine conveying function and system |
| WO2016165634A1 (en) * | 2015-04-14 | 2016-10-20 | 上海交通大学 | Cold and hot treatment device for melanoma |
-
2014
- 2014-02-20 CN CN201420074065.6U patent/CN203724206U/en not_active Withdrawn - After Issue
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103767783A (en) * | 2014-02-20 | 2014-05-07 | 中国科学技术大学 | Freezing and heating knife with medicine conveying function and system |
| CN103767783B (en) * | 2014-02-20 | 2015-10-28 | 中国科学技术大学 | A kind of cold and hot cutter with drug delivery capabilities and system |
| WO2016165634A1 (en) * | 2015-04-14 | 2016-10-20 | 上海交通大学 | Cold and hot treatment device for melanoma |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20140723 Effective date of abandoning: 20151028 |
|
| C25 | Abandonment of patent right or utility model to avoid double patenting |