CN203693604U - Implantable bio-energy blood glucose monitor - Google Patents

Implantable bio-energy blood glucose monitor Download PDF

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Publication number
CN203693604U
CN203693604U CN201320870349.1U CN201320870349U CN203693604U CN 203693604 U CN203693604 U CN 203693604U CN 201320870349 U CN201320870349 U CN 201320870349U CN 203693604 U CN203693604 U CN 203693604U
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China
Prior art keywords
main body
energy
power generation
generating main
blood sugar
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Expired - Fee Related
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CN201320870349.1U
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Chinese (zh)
Inventor
张�浩
曲丹
徐志云
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Priority to CN201320870349.1U priority Critical patent/CN203693604U/en
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Abstract

The utility model provides an implantable bio-energy blood glucose monitor, comprising a sensor for monitoring the blood glucose level, a signal transmission part, a signal reception part and a power generation part, wherein the power generation part comprises a power generation body, adjusting ends, an output electrode, a power storage unit and an encapsulation layer; the power generation body is used for wrapping an aorta, and is of a multi-layer film structure; the power generation body comprises a piezoelectric material layer in the central layer, a first electrode layer and a second electrode layer located respectively at the two sides of the piezoelectric material layer; the adjusting ends are positioned at the two ends of the power generation body and are used for adjusting the length of the power generation body; the output electrode is used for transmitting electrical energy to the power storage unit; the power storage unit is used for storing the electrical energy and supplying power for the blood glucose sensor and the signal transmission part; the encapsulation layer covers the surfaces of the power generation body, the adjusting ends and the output electrode. By applying the implantable bio-energy blood glucose monitor, a battery does not need to be used as a power source any more.

Description

Implantating biological energy blood sugar monitoring instrument
Technical field
This utility model relates to a kind of implantating biological energy blood sugar monitoring instrument, belongs to medical instruments field.
Background technology
Diabetes are commonly encountered diseases and frequently-occurring diseases of middle-older patient, as a kind of lifelong participation disease, still lack the treatment means of thorough radical cure at present.Patient needs regular venous blood samples with Monitoring Blood Glucose level conventionally.Blood sugar monitoring instrument in implantable can Real-Time Monitoring tissue blood sugar concentration, do not need has taking a blood sample of wound property at every turn.But no matter the implanted blood sugar monitoring instrument of which kind of type, all needs to use implantable minicell that electric energy is provided.Once the energy content of battery is exhausted, the replacing battery of just need to again performing the operation.Both can cause on physiology and spiritual misery to patient, and also can increase the financial burden of patient and family thereof.
At inside of human body, flowing of the contractile motion of heart and blood all has stable and continual kinetic energy.If can gather wherein sub-fraction kinetic energy and be converted into electric energy, will be expected to provides electric energy for various implanted blood-sugar detecting instruments.But because heart is human body " electromotor ", inappropriate collection heart kinetic energy will inevitably affect the function of heart, even causes heart and injury.In addition, traditional induction electromotor volume based on Faraday's law is large, complex structure, and uncomfortable zoarium is implanted into.
Utility model content
For addressing the above problem, the implanted blood sugar monitoring instrument that this utility model provides in a kind of implantable and indirect utilization heart biology can be powered, it is characterized in that, comprise for the sensor of Monitoring Blood Glucose level, can wireless transmission Monitoring Data signal emission part, be positioned at external signal receiving part and Power Generation Section.Wherein, Power Generation Section comprises generating main body, adjustable side, output electrode, energy storage unit and encapsulated layer.Wherein, generating main body is used for holding aorta, the mechanical energy being produced when gathering aortectasia, and be converted into electric energy.Generating main body is multi-layer film structure, comprises the piezoelectric material layer that is positioned at central core, and lays respectively at the first electrode layer and the second electrode lay of piezoelectric material layer both sides.Adjustable side is positioned at the two ends of generating main body, for regulating the length of generating main body.Output electrode is used for power delivery to energy storage unit.Energy storage unit is also blood glucose sensor and the power supply of signal emission part for storage of electrical energy.Encapsulated layer is covered in the surface of generating main body, adjustable side and output electrode.
In addition, implantating biological energy blood sugar monitoring instrument of the present utility model can also have such feature: wherein, piezoelectric material layer contains nanoscale piezoelectric, and nanoscale piezoelectric is any one in piezoquartz, piezoelectric ceramics and organic piezopolymer.
In addition, implantating biological energy blood sugar monitoring instrument of the present utility model can also have such feature: wherein, piezoquartz, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
In addition, implantating biological energy blood sugar monitoring instrument of the present utility model can also have such feature: wherein, power storage portion is miniature rechargeable battery or electric capacity.
In addition, implantating biological energy blood sugar monitoring instrument of the present utility model can also have such feature: also comprise that current rectifying and wave filtering circuit is connected between energy storage unit and output electrode.
In addition, implantating biological energy blood sugar monitoring instrument of the present utility model can also have such feature: wherein, and any one during the stitching of fixed form use surgical thread, titanium clamp pincers folder or the binding agent of adjustable side are bonding.
In addition, implantating biological energy blood sugar monitoring instrument of the present utility model can also have such feature: wherein, one end of adjustable side is single latch, the tip of this latch is level and smooth and towards the outside of generating main body, the other end of adjustable side is draw-in groove, inside one side of draw-in groove has the teeth groove matching with latch, and opposite side is plane, and latch and draw-in groove fasten.
In addition, implantating biological energy blood sugar monitoring instrument of the present utility model can also have such feature: wherein, encapsulated layer is using the flexible macromolecule insulant of good biocompatibility as encapsulating material.
In addition, implantating biological energy blood sugar monitoring instrument of the present utility model can also have such feature: Power Generation Section is less than 140mmHg to aortal pressure.
Utility model effect and effect
Implantating biological energy blood sugar monitoring instrument of the present utility model, by implanting the energy that nanoscale piezoelectric produced when gathering aortectasia and being converted into electric energy, as its energy source.Therefore need only heartbeat, this utility model can utilize patient's self bioenergy that electric energy is provided, and has removed from and has used battery necessity as power supply, has solved the problem of changing battery after the energy content of battery is exhausted by operation.
Because this utility model adopts nanoscale piezoelectric as generating main body, not only can effectively the bioenergy in body be converted into electric energy, and volume is small, be more suitable for body and be implanted into.
Because having adopted soft loop configuration, this utility model is paperwrapped in aortal outer wall, and can quantitatively control native system to aortal pressure, therefore mechanical energy that both can be efficiently, produce while gathering aortectasia fully, can not produce obviously impact to cardiac function again.
In addition, because adopting the flexible macromolecule insulant of good biocompatibility, this utility model encapsulates, therefore can be by generating main body and internal milieu isolation, and the pressure that also aorta wall deformation can be produced effectively conduct to piezoelectric.
In addition, utilize the adjustable side capable of regulating generating main body at generating main body two ends to hold aortal tensity, thus the deformation degree of adjustable piezoelectric material and output electric weight.Owing to not containing piezoelectric and electrode layer in adjustable side, therefore use the clamping timing of sutures or titanium can not damage the structure of generating main body again.
And, because generating main body of the present utility model is positioned at aorta outside, directly do not contact with blood, thereby do not have the risk of thrombosis and apoplexy (myocardial infarction or cerebral infarction).
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the implantating biological energy blood sugar monitoring instrument of this utility model embodiment mono-;
Fig. 2 is the schematic diagram of the generating main body of this utility model embodiment mono-;
Fig. 3 is the internal structure profile of the generating main body of this utility model embodiment mono-;
Fig. 4 is the partial enlarged drawing in main body A region of generating electricity in Fig. 3;
Fig. 5 is that the main body of generating electricity in this utility model embodiment mono-is installed on Supraaortic sectional view;
Fig. 6 is that in this utility model embodiment tetra-, adjustable side is the schematic diagram of latch structure; And
Fig. 7 is the circuit diagram of this utility model embodiment mono-.
The specific embodiment
The specific embodiment of blood sugar monitoring instrument of the present utility model is below described with reference to the accompanying drawings,
< embodiment mono->
Fig. 1 is the schematic diagram of the implantating biological energy blood sugar monitoring instrument of this utility model embodiment mono-.As shown in Figure 1, implantating biological energy blood sugar monitoring instrument 100 comprises blood glucose sensor 19, signal emission part 16, Power Generation Section 200 and is positioned at external signal receiving part 300.Power Generation Section 200 comprises generating main body 11, output electrode 14, current rectifying and wave filtering circuit 12 and energy storage unit 13.Generating main body 11 is resilient loop configuration, can be surrounded on aorta 18 around, and generating main body 11 inside have piezoelectric, can utilize aortal deformation to produce electric energy.After the output electrode 14 of generating main body 11, connected current rectifying and wave filtering circuit 12, the electric energy that the main body 11 that makes to generate electricity is exported becomes stable.After energy storage unit 13 is connected in current rectifying and wave filtering circuit 12, for store electrical energy, and the blood glucose sensor 19 and the signal emission part 16 that are implantating biological energy blood sugar monitoring instrument 100 by wire 15 are powered.
Fig. 2 is the schematic diagram of the generating main body of this utility model embodiment mono-.As shown in Figure 2, the shape that the original state of generating main body 11 is open loop, respectively has an adjustable side 23 at the two ends of loop configuration, in the time being arranged on aorta outer wall, two adjustable sides need to be linked together.Outer surface in generating main body 11 and adjustable side 23 is coated with encapsulated layer 22.In generating main body 11, there are two output electrodes 14, for the electric energy output that generating main body 11 is produced.
Fig. 3 is the internal structure profile of the generating main body of this utility model embodiment, as shown in Figure 3, the inside of generating main body 11 is multi-layer film structure, comprise the nanoscale piezoelectric 111 that is positioned at main center's layer, and lay respectively at the first electrode layer 112 and the second electrode lay 113 of piezoelectric both sides.Encapsulated layer 22 adopts the flexible macromolecule insulant with biocompatibility, is covered in the surface of generating main body 11 and output electrode 14, and extends to form each adjustable side 23, both sides to the outside of generating main body 11.
Fig. 4 is the partial enlarged drawing in main body A region of generating electricity in Fig. 3, as shown in Figure 4, is positioned at the nanoscale piezoelectric 111 of generating main body 11 central cores.The high layer materials of conductivity such as the first electrode layer 112 and the second electrode lay 113 employings are golden or silver-colored are made, and are connected with nanoscale piezoelectric 111.
Generating main body 11 is bending circulus under naturalness, and its membrane structure has good elasticity, therefore can be submissive hold aorta.
While implantation in vivo, can generating main body 11 be implanted to aorta around and hold aorta by operating method.Fit tightly again the energy being produced to gather aorta deformation with aortal outer wall by adjusting adjustable side 23 make to generate electricity main body 11.
May increase the workload of heart 17 to aortal excessive compressing, therefore can between generating main body 11 and aorta wall, to measure generating main body 11 to aortal pressure, avoid it to exert an adverse impact to heart by interim placement force sensor.
Because piezoelectric material layer and electrode layer are not contained in the inside of adjustable side 23, therefore, in the time using sutures or titanium folder that the both sides of adjustable side 23 are closed, can not cause damage to generating main body 11.
Fig. 5 is that the main body of generating electricity in this utility model embodiment is installed on Supraaortic sectional view.The work process of implantating biological energy blood sugar monitoring instrument of the present utility model is described below in conjunction with Fig. 1 and Fig. 5.
As shown in Figure 1 and Figure 5, generating main body 11 is surrounded on aorta 18.In the time that heart 17 shrinks, the impact of blood flow is expanded aorta 18, as shown in Figure 5, aorta wall 45 can produce a pressure F to generating main body 11, make piezoelectric material layer 111 that deformation occur, thereby form electric potential difference generation current at its two ends, electric current conducts to output electrode 14 by the first electrode layer 112 and the second electrode lay 113, by entering energy storage unit 13 after current rectifying and wave filtering circuit 12, electric energy energy memory element 13 is miniature rechargeable battery again.Energy storage unit 13 is blood glucose sensor 19 and the signal emission part 16 to implantating biological energy blood sugar monitoring instrument by supply of electrical energy again.
Fig. 7 is the circuit diagram of this utility model embodiment.As shown in Figure 7, generating main body 11 is connected with current rectifying and wave filtering circuit 12, the electric energy that generating main body 11 produces charges to energy storage unit 13 after current rectifying and wave filtering circuit 12, and it is blood glucose sensor and the power supply of signal emission part in the present embodiment that energy storage unit 13 is used to electrical appliance.
< embodiment bis->
In the present embodiment, blood glucose sensor, signal emission part and the generating shape of main body and the setting of adjustable side of implantating biological energy blood sugar monitoring instrument are identical with embodiment mono-, difference part is in the present embodiment, the piezoelectric material layer employing nanoscale piezoceramic material of generating main body.
Another one is distinguished part and is, it is clamping fixed that in the present embodiment, adjustable side adopts titanium.
< embodiment tri->
In the present embodiment, blood glucose sensor, signal emission part and the generating shape of main body and the setting of adjustable side of implantating biological energy blood sugar monitoring instrument are identical with embodiment mono-, difference part is in the present embodiment, the piezoelectric material layer of generating main body adopts piezopolymer, and adjustable side adopts the bonding mode of binding agent to be fixed.
< embodiment tetra->
In the present embodiment, blood glucose sensor, signal emission part and the generating shape of main body and the setting of adjustable side of implantating biological energy blood sugar monitoring instrument are identical with embodiment mono-, difference part is in the present embodiment, as shown in Figure 6, one end of adjustable side 61 is single latch, crown is level and smooth and towards the outside of generating main body, to prevent the tissues such as crown damage heart or aorta.The other end of adjustable side 61 is draw-in groove, and inside one side of draw-in groove has the teeth groove matching with latch, and opposite side is plane.In the time that aorta outer wall is fixed on in Power Generation Section, slowly latch is inserted to draw-in groove, use micro pressure sensor to detect the pressure of generating main body to aorta outer wall simultaneously, slowly tighten up latch, until this pressure reaches 120mmHg-140mmHg.
Certain implantating biological energy blood sugar monitoring instrument of the present utility model is not limited to the design described in above embodiment, and its piezoelectric material layer, electrode layer all can adopt various existing appropriate materials to make with encapsulated layer.

Claims (7)

1. an implantating biological energy blood sugar monitoring instrument, is characterized in that, comprising:
For the sensor of Monitoring Blood Glucose;
For blood glucose level data being radioed to the signal emission part of external receiving system;
For receiving the signal receiving part of described blood glucose level data; And
For the Power Generation Section of described sensor and the power supply of described signal emission part,
Wherein, described Power Generation Section comprises generating main body, adjustable side, output electrode, energy storage unit and encapsulated layer,
Described generating main body is used for holding aorta, the mechanical energy being produced when gathering aortectasia, and be converted into electric energy,
Described generating main body is multi-layer film structure, comprises the piezoelectric material layer that is positioned at central core, and lays respectively at the first electrode layer and the second electrode lay of described piezoelectric material layer both sides,
Described adjustable side is positioned at the two ends of described generating main body, for regulating the length of described generating main body,
Described output electrode for by power delivery to energy storage unit,
Described energy storage unit is also described sensor and the power supply of signal emission part for storage of electrical energy,
Described encapsulated layer is covered in the surface of described generating main body, described adjustable side, described energy storage unit and described output electrode.
2. implantating biological energy blood sugar monitoring instrument as claimed in claim 1, is characterized in that:
Wherein, described power storage portion is miniature rechargeable battery or electric capacity.
3. implantating biological energy blood sugar monitoring instrument as claimed in claim 1, is characterized in that, also comprises:
Current rectifying and wave filtering circuit, is connected between described energy storage unit and described output electrode.
4. implantating biological energy blood sugar monitoring instrument as claimed in claim 1, is characterized in that:
Wherein, the fixed form of described adjustable side use sutures, titanium folder and bonding in any one.
5. implantating biological energy blood sugar monitoring instrument as claimed in claim 1, is characterized in that:
Wherein, one end of described adjustable side is single latch, and the tip of this latch is level and smooth and towards the outside of generating main body, the other end of described adjustable side is draw-in groove, inside one side of draw-in groove has the teeth groove matching with described latch, and opposite side is plane, and described latch and described draw-in groove fasten.
6. implantating biological energy blood sugar monitoring instrument as claimed in claim 1, is characterized in that:
Wherein, described encapsulated layer is using the flexible macromolecule insulant of good biocompatibility as encapsulating material.
7. implantating biological energy blood sugar monitoring instrument as claimed in claim 1, is characterized in that:
Described Power Generation Section is less than 140mmHg to aortal pressure.
CN201320870349.1U 2013-12-26 2013-12-26 Implantable bio-energy blood glucose monitor Expired - Fee Related CN203693604U (en)

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Application Number Priority Date Filing Date Title
CN201320870349.1U CN203693604U (en) 2013-12-26 2013-12-26 Implantable bio-energy blood glucose monitor

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Application Number Priority Date Filing Date Title
CN201320870349.1U CN203693604U (en) 2013-12-26 2013-12-26 Implantable bio-energy blood glucose monitor

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CN203693604U true CN203693604U (en) 2014-07-09

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104739427A (en) * 2013-12-26 2015-07-01 中国人民解放军第二军医大学 Implantable biological energy blood glucose monitor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104739427A (en) * 2013-12-26 2015-07-01 中国人民解放军第二军医大学 Implantable biological energy blood glucose monitor

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140709

Termination date: 20161226

CF01 Termination of patent right due to non-payment of annual fee