CN203534068U - Freeze dryer for cooling drug preparations - Google Patents
Freeze dryer for cooling drug preparations Download PDFInfo
- Publication number
- CN203534068U CN203534068U CN201320633166.8U CN201320633166U CN203534068U CN 203534068 U CN203534068 U CN 203534068U CN 201320633166 U CN201320633166 U CN 201320633166U CN 203534068 U CN203534068 U CN 203534068U
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- dividing plate
- cooling
- freeze dryer
- spray head
- conduction oil
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Abstract
Provided is a freeze dryer for cooling drug preparations. The freeze dryer for cooling the drug preparations comprises a box body, a freezing unit and a conduction oil conveying device, wherein a plurality of layers of separating plates are arranged inside the box body, a plurality of bottles of preparations are placed on the separating plates, the freezing unit and the hydraulic conduction oil conveying device are connected with the separating plates, and are used for conveying conduction oil to the separating plates to freeze the preparations on the separating plates, and a rotary spray head is arranged on the top of the box body, and is used for spraying water to the preparations on the separating plates to cool the preparations. Due to the fact that a fixed spray head is replaced by the rotary spray head, the rotary spray head can carry out spray cleaning in the box body in a multidirectional, multi-angle and liftable mode, spray cleaning is carried out on each corner of the box body, the cleaning effect is better, and the problem that dead corners on the box body or the separating plates cannot be easily cleaned up is solved; in addition, due to the fact that a cooling system is additionally arranged, and is used for carrying out secondary cooling on the conduction oil, influence of pressure caused by overheated conduction oil on a circulating pump is reduced, and the service life of the circulating pump is effectively prolonged.
Description
Technical field
The utility model relates to medicine cooling device, refers in particular to a kind of freeze dryer for cooling medicine preparation.
Background technology
Vacuum freeze drying also claims freeze-drying, first water-containing materials is freezed to below eutectic temperature, make free water wherein become ice, then, in dry storehouse under suitable vacuum condition, by the method for heating, make ice distillation or make adsorbed water evaporation, from material, overflow and remove, thereby obtaining the technology of dried product.
In sublimation process, in material, having distillation air-flow constantly outwards overflows, under the effect of air-flow, some tiny material fragments will fly away each corner in casing along with air-flow, if do not removed, not only may cause the cross-infection of different material, when more serious, accumulating the time will grow microorganism after long, cause bacterial reproduction, very large to medicine preparation harm, have a strong impact on medicine quality.And existing fixed spray head, spraying range is very little, only can vertically spray casing or partition part region, can not clean a lot of dead angles of casing, therefore, is necessary each corner of casing effectively to clean, and avoids it in corner breed bacteria.On the other hand, circulating in process of conduction oil, when hot oil temperature is too high, will circulating pump be caused to certain pressure, cause it long-term overheated and damage, affect service life and efficiency.
Utility model content
Based on the deficiencies in the prior art, main purpose of the present utility model is to provide a kind of freeze dryer that can effectively clean each corner of casing.
Another main purpose of the present utility model is to provide a kind of temperature that can reduce conduction oil, avoids the freeze dryer of the overheated overvoltage of circulating pump.
The utility model provides a kind of freeze dryer for cooling medicine preparation, comprise casing, freezing unit and conduction oil transmitting device, wherein, described casing is built-in with some layers of dividing plate, on described dividing plate, be placed with some vial formulations, described freezing unit is connected with dividing plate respectively with hydraulic pressure transmitting device, described freezing unit and hydraulic pressure transmitting device are respectively to dividing plate transmission conduction oil, to the preparation on dividing plate, carry out freezing, wherein, described casing top is provided with rotary spray head, cooling to the preparation water spray on dividing plate by rotary spray head.
Preferably, described rotary spray head is assemblied on the top board of casing by elevating lever, it is located between ground floor dividing plate and roof box, by elevating lever, adjust up and down the spacing between spray head and dividing plate, the top board of casing is fixed in described elevating lever one end, the other end is installed rotary spray head, drives rotary spray head to take elevating lever as axle rotates, and makes its mobile height of adjusting spray head up and down.
Preferably, described freeze dryer also further increases cooling system, and described cooling system comprises valve and heat exchanger, and described valve is arranged between freezing unit and dividing plate water inlet end.By cooling system, further conduction oil is carried out to decrease temperature and pressure control, reduce the overheated pressure that circulating pump is caused of conduction oil.
Compared with prior art, a kind of freeze dryer for cooling medicine preparation of the utility model has adopted rotary spray head to substitute fixed spray head, multi-faceted, multi-angle, liftably in casing, spray cleaning, cleaning is sprayed in each corner of casing, cleaning performance is better, has solved the problem that the dead angle on casing or dividing plate is difficult for cleaning up; In addition, have additional cooling system, conduction oil is lowered the temperature again, to reduce the impact of the overheated pressure that circulating pump is brought of conduction oil, effectively extend the life-span of circulating pump.
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of freeze dryer for cooling medicine preparation of the utility model.
The specific embodiment
Shown in Fig. 1, the utility model provides a kind of freeze dryer for cooling medicine preparation, comprise casing 1, freezing unit 2 and conduction oil transmitting device 3, wherein, described casing 1 is built-in with some layers of dividing plate 10, on described dividing plate 10, be placed with some vial formulations, described freezing unit 2 is connected with dividing plate 10 respectively with conduction oil transmitting device 3, described freezing unit 2 and conduction oil transmitting device 3 are respectively to dividing plate 10 transmission conduction oils, to the preparation on dividing plate 10, carry out freezing, wherein, described casing 1 top is provided with rotary spray 4, cooling to the preparation water spray on dividing plate 10 by rotary spray 4.
Wherein, the built-in some layers of dividing plate 10 that are placed with of described casing 1, each dividing plate 10 is parallel to each other, parallel with the base plate of casing 1, between each dividing plate 10, keep a determining deviation, to place, treat that freezing medicine preparation, medicine preparation neatly lie against on each layer of dividing plate 10, by freezing unit, to it, carry conduction oil, so that medicine preparation is freezed.The lifting of described dividing plate 10 boosts to realize by the conduction oil transmitting device 3 conveying liquid force feed transmission on casing 1.The hydraulic oil of high pressure provides by oil pump, by three-way magnetic valve, controls top or the bottom that hydraulic oil enters the piston in oil cylinder, and drivening rod rises or declines.While freeze drying box being carried out to high-temperature sterilization after oil cylinder is parked in a certain position, in-oil cylinder oily expanded by heating oil pressure increases severely, cause after sterilizing three-way magnetic valve stuck and cannot lifting shelf, affect next step operation of freeze dryer, when the oil pressure of oil cylinder is too high, in-oil cylinder part hydraulic oil need to be laid down, just can guarantee the switch motion of magnetic valve.
In preferred embodiment one of the present utility model, the top of described casing 1 is provided with rotary spray 4, described rotary spray 4 is assemblied on the top board of casing 1 by elevating lever, be located between ground floor dividing plate and roof box, by elevating lever, adjust up and down the spacing between rotary spray 4 and dividing plate 10.The top board of casing 1 is fixed in described elevating lever one end, and the other end is installed rotary spray 4, drives rotary spray 4 to take elevating lever and rotates as axle.A described rotary spray 4 connection rinse water, rinse water is by a rotary spray 4 importing casing 1, by described rotary spray 4, to the surrounding of casing, spray rinse water rotatably, effectively to clean each corner of casing, improve efficiency and quality that casing and dividing plate clean, effectively cleaned dead angle.
In preferred embodiment two of the present utility model, described freeze dryer also further increases cooling system 5, and described cooling system 5 is serially connected with between freezing unit 2 and the water inlet end of dividing plate 10.Described freezing unit 2 imports respectively the below of each dividing plate 10 by aqueduct.Described cooling unit 2 comprises heat conduction oil circulating pump 20 and First Heat Exchanger 22, described cooling system 5 comprises valve 50 and the second heat exchanger 52, valve is serially connected with between freezing unit 2 and dividing plate water inlet end, whether the unlatching by by-pass valve control or close, cool through cooling system 5 to control conduction oil.Conduction oil imports each layer of dividing plate by heat conduction oil cylinder, by delivery outlet, transfer to freezing unit 2, by heat conduction oil circulating pump 20, be delivered in First Heat Exchanger 22, external refrigerating system liquid imports in heat exchanger, conduction oil is lowered the temperature, if the temperature of conduction oil is still too high, also can close the valve 50 of cooling system, at this moment, conduction oil transfers in the second heat exchanger 52 of cooling system 5, by cooling water, conduction oil is further lowered the temperature, conduction oil after cooling inputs to the water inlet end of dividing plate again, conduction oil is through reducing temperature twice, while flowing into heat conduction oil circulating pump 20 again, temperature declines, pressure also declines, avoided the overheated heat conduction oil circulating pump 20 of giving of conduction oil to bring larger pressure, effectively protect each unit, extended the life-span of circulating pump.When the temperature of conduction oil is moderate, open the valve 50 of cooling system 5, lead the water inlet end that is back to dividing plate conduction oil direct circulation.According to the temperature of conduction oil, carry out the opening and closing of by-pass valve control, simple.
Medicine carries out vacuum or nitrogen sealing after freeze-drying, and with starvation, if deposit at low temperatures, moisture, air, three factors that affect medicine sex change of temperature are all effectively controlled again, and make medicine can within the longer time, obtain good preservation.
The process of freeze-drying is as follows:
Step 1) first by drug solution at low temperatures (generally below minus 20 degrees) quick freezing become solid, guarantee that all liq all becomes solid, deposits on dividing plate;
Step 2), by vacuum pump apparatus, vacuum state (being generally no more than 40pa) will be kept in body of freeze dryer continuing;
Step 3) is opened box partition and is heated up, and due to vacuum state, in solid matter, moisture is directly sublimed into steam by solid at normal temperatures, and the steam of volatilization is used cold hydrazine equipment to discharge casing in time;
Step 4) is set after requirement completely or extremely until moisture evaporation in solid matter, tamponade in casing under nitrogen protection or vacuum state, outlet.
Claims (7)
1. the freeze dryer for cooling medicine preparation, comprise casing, freezing unit and conduction oil transmitting device, wherein, described casing is built-in with some layers of dividing plate, on described dividing plate, be placed with some vial formulations, described freezing unit is connected with dividing plate respectively with hydraulic pressure transmitting device, described freezing unit and hydraulic pressure transmitting device are respectively to dividing plate transmission conduction oil, to the preparation on dividing plate, carry out freezing, it is characterized in that: described casing top is provided with rotary spray head, cooling to the preparation water spray on dividing plate by rotary spray head.
2. according to claim 1 for the freeze dryer of cooling medicine preparation, it is characterized in that: described rotary spray head is assemblied on the top board of casing by elevating lever, by elevating lever, adjusts up and down the spacing between spray head and dividing plate.
3. according to claim 2 for the freeze dryer of cooling medicine preparation, it is characterized in that: the top board of casing is fixed in described elevating lever one end, the other end is installed rotary spray head, drives rotary spray head to take elevating lever as axle rotation.
4. according to claim 3 for the freeze dryer of cooling medicine preparation, it is characterized in that: described dividing plate parallel arrangement.
5. according to claim 4 for the freeze dryer of cooling medicine preparation, it is characterized in that: described rotary spray head is located between ground floor dividing plate and roof box.
6. according to claim 4 for the freeze dryer of cooling medicine preparation, it is characterized in that: described freeze dryer also further increases cooling system, and described cooling system comprises valve and heat exchanger, described valve is arranged between freezing unit and dividing plate water inlet end.
7. according to claim 6 for the freeze dryer of cooling medicine preparation, it is characterized in that: described freezing unit imports respectively the below of each dividing plate by aqueduct.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320633166.8U CN203534068U (en) | 2013-10-14 | 2013-10-14 | Freeze dryer for cooling drug preparations |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320633166.8U CN203534068U (en) | 2013-10-14 | 2013-10-14 | Freeze dryer for cooling drug preparations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203534068U true CN203534068U (en) | 2014-04-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320633166.8U Expired - Fee Related CN203534068U (en) | 2013-10-14 | 2013-10-14 | Freeze dryer for cooling drug preparations |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203534068U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104132529A (en) * | 2014-07-25 | 2014-11-05 | 上海共和真空技术有限公司 | Conduction oil cooling system and method for triple heat exchange plate-type freeze dryer |
-
2013
- 2013-10-14 CN CN201320633166.8U patent/CN203534068U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104132529A (en) * | 2014-07-25 | 2014-11-05 | 上海共和真空技术有限公司 | Conduction oil cooling system and method for triple heat exchange plate-type freeze dryer |
| CN104132529B (en) * | 2014-07-25 | 2016-05-25 | 上海共和真空技术有限公司 | For the conduction oil cooling means of the board-like freeze dryer of triple heat exchanges |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140409 Termination date: 20141014 |
|
| EXPY | Termination of patent right or utility model |