CN203432927U - Low-field nuclear magnetic resonance probe based on PCB (printed circuit board) planar coil - Google Patents
Low-field nuclear magnetic resonance probe based on PCB (printed circuit board) planar coil Download PDFInfo
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- CN203432927U CN203432927U CN201320405489.1U CN201320405489U CN203432927U CN 203432927 U CN203432927 U CN 203432927U CN 201320405489 U CN201320405489 U CN 201320405489U CN 203432927 U CN203432927 U CN 203432927U
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Abstract
The utility model relates to a low-field NMR (nuclear magnetic resonance) probe based on a PCB (printed circuit board) planar coil. The probe structurally comprises a planar coil, an upper part lead, a first bonding pad, a second bonding pad, a metallized inner through hole, a metallized outer through hole, a bottom part lead and a PCB (printed circuit board) substrate; the outer end of the planar coil is connected with the first bonding pad through the upper part lead; the inner end of the planar coil is connected with the second bonding pad through the metallized inner through hole, the bottom part lead and the metallized outer through hole. The existing NMR probe has the problems of complex process, high cost, long cycle, incapability of batch production, high impedance and the like in the manufacturing process. The NMR probe based on the PCB planar coil, provided by the utility model adopts a PCB technique and has the advantages of simple manufacturing, low cost, short cycle and capability of batch production and the like. The NMR probe based on the PCB planar coil, which is provided by the utility model, is mainly applied to the field of low-field NMR (the main magnetic field B0<=1.4T) and also can be applied to the field of NMR imaging, even the field of high-field NMR, when the self-resonant frequency of the planar coil is in the range of hundreds of mega.
Description
Technical field
The utility model relates to a kind of low NMR probe based on printed circuit board (PCB) (printed circuit board, PCB) planar coil.
Background technology
Nuclear magnetic resonance (nuclear magnetic resonance, NMR) technology is well-known in analysis field because of Non-Destructive Testing, is widely used in chemical structure analysis, molecular dynamics, diagnosing image and other field.In recent years, the magnetic nuclear resonance analyzer that is applied to analyze is towards low cost, high precision, portable future development, and NMR based on malcoils probe is as one of vitals of magnetic nuclear resonance analyzer, the send and receive of signal is had to decisive role.Therefore, find a kind of with low cost, method is simple, highly sensitive, coil that can batch making, becomes the focus of current research.At present, there is many research to relate to making and the application of malcoils.(the Design and analysis of microcoils for NMR microscopy.Journal of Magnetic Resonance Series B such as Peck, 1995.108 (2): p.114-124.) the manual solenoid coil that is wound around on kapillary, coil q performance is higher, but because of manual winding, can not batch making.(the Planar microcoil-based microfluidic NMR probes.Journal of Magnetic Resonance such as Massin, p.242-255.) and (the Multilayer high-aspect-ratio RF coil for NMR applications.Microsystem Technologies such as Hsieh 2003.164 (2):, 2011.17 (8): p.1311-1317.) based on glass substrate, use photoetching and electroplating technology, making is easy to the integrated MEMS (micro electro mechanical system) of microchannel (micro electro mechanic system, MEMS) coil, but loop construction porous and rough surface.(the Afully MEMS-compatible process for3D high aspect ratio micro coils obtained with an automatic wire bonder.Journal of Micromechanics and Microengineering such as Kratt, 2010.20 (1): p.015021.) combined standard MEMS method, adopt automatic lead bonding techniques batch making 3D miniature coils, but the diameter of the bonding line coil that this method makes is confined to the physical strength of photoetching and SU-8 pillar.(the Using microcontact printing to fabricate microcoils on capillaries for high resolution proton nuclear magnetic resonance on nanoliter volumes.Applied Physics Letters such as Rogers, 1997.70 (18): p.2464-2466.) on kapillary, use micro-printing and electro-plating method to make solenoid coil, although method for making is novel, coil impedance performance is very high.(the H-1NMR Detection of superparamagnetic nanoparticles at 1 T using a microcoil and novel tuning circuit.Journal of Magnetic Resonance such as Sillerud, 2006.181 (2): p.181-190.) adopt focused ion beam (focused ion beam, FIB) process technology is made the solenoid miniature coils of diameter 550 μ m, but its cost of manufacture is expensive.(the Adhesive-based liquid metal radio-frequency microcoilfor magnetic resonance relaxometry measurement.Lab on a Chip such as Kong, 2012.) based on heap multilayered stack cut adhesive, make liquid metal miniature coils, because the conductivity of liquid metal gallium is low, coil sensitivity is lower.
Utility model content
Technical matters: to be solved in the utility model be during existing coil is made, there is complex process, cost is high, the cycle is long, can not batch, the problem such as impedance height.
Technical scheme: in order to solve the problems of the technologies described above, the utility model provides that a kind of low cost, fabrication cycle based on PCB planar coil is short, low NMR probe that can mass, this probe is based on PCB technology, and its structure is comprised of planar coil, through hole, lead-in wire and pad.
Low-field nuclear magnetic resonance probe based on printed circuit board (PCB) planar coil of the present utility model be take PCB substrate as substrate, above PCB substrate, be provided with planar coil, top lead-in wire, the first pad and the second pad, the outer end of planar coil is gone between and is connect the first pad by top, and the inner of planar coil is connected with the second pad with metallization accessibke porosity by metallization inner via hole, bottom lead.
PCB backing material adopts glass fibre, insulating material that fabric material and resin do not form.
Be positioned at planar coil, through hole, lead-in wire, pad and be integrally connected, planar coil, through hole, lead-in wire and pad all adopt copper product to make, and the outside surface of metallic copper also can turmeric or gold-plated.
The planform of planar coil is spiral circle, square, hexagon, octagon and n limit shape; N >=4 are even number.
NMR probe is mainly used in low-field nuclear magnetic resonance field (main field B
0≤ 1.4T); When the self-resonant frequency of planar coil is during in hundreds of million scope, also can be applied to even high-field nuclear magnetic resonance field, Magnetic resonance imaging field.
PCB planar coil (1) both can be independent separately with peripheral circuit, adopts spun gold (or aluminium wire) bonding; Also PCB planar coil (1) and peripheral circuit can be integrated and connected on same PCB.
In such scheme, tested liquid sample is put into the kapillary of closed at both ends, and kapillary is directly put into directly over PCB planar coil; Or tested solid sample directly puts on microslide, microslide is directly put into directly over PCB planar coil.
Beneficial effect:
1, this low the NMR probe based on PCB planar coil can realize low cost that the utility model provides, short period, technique be simple, can make by mass.
2, this low the NMR probe based on PCB planar coil that the utility model provides, the metallic copper material of employing makes PCB planar coil resistance value lower.
3, this low the NMR probe based on PCB planar coil that the utility model provides, can apply the sample analysis in low-field nuclear magnetic resonance field, in part situation (self-resonant frequency of planar coil is in hundreds of million scopes), can be applied to even high-field nuclear magnetic resonance field, Magnetic resonance imaging field.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the utility model is further illustrated.
Fig. 1 is that the axle that waits of the utility model structure measures intention.
Fig. 2 is the cross sectional representation of the utility model structure.
Fig. 3 is the vertical view of the utility model structure.
In figure: 1. planar coil, 21. metallization inner via holes, 22. metallization accessibke porosities, 31. tops lead-in wires, 32. bottom leads, 41. first pads, 42. second pads, 5.PCB substrate.The thickness h of planar coil 1, the width w of planar coil 1, the coil-span s of planar coil 1.
Embodiment
For making the purpose of this utility model, technical scheme and advantage clearer, below in conjunction with specific embodiment, and with reference to accompanying drawing, the utility model is further described.
As shown in Figure 1, what the utility model provided is this based on printed circuit board (PCB) (printed circuit board, PCB) low NMR sonde configuration of planar coil, this sonde configuration comprises planar coil 1, metallization inner via hole 21, metallization accessibke porosity 22, top lead-in wire 31, bottom lead 32, the first pad 41, the second pad 42 and PCB substrate 5, the outer end of planar coil 1 is gone between and 31 is connected to the first pad 41 by top, the inner of planar coil 1 is connected to bottom lead 32 through metallization inner via hole 21, through metallization accessibke porosity 22, be connected to the second pad 42 again.
This NMR probe based on PCB is mainly used in low-field nuclear magnetic resonance field (main field B
0≤ 1.4T); When the self-resonant frequency of planar coil is during in hundreds of million scope, can be applied to even high-field nuclear magnetic resonance field, Magnetic resonance imaging field.
As shown in Figure 2, planar coil 1, metallization inner via hole 21, metallization accessibke porosity 22, top lead-in wire 31, bottom lead 32, the first pad 41, the second pad 42 are integrally connected, planar coil 1, metallization inner via hole 21, metallization accessibke porosity 22, top lead-in wire 31, bottom lead 32, the first pad 41 and the second pad 42 all adopt the copper product of Low ESR rate to make, oxidized in order to prevent metallic copper, its outside surface mainly adopts turmeric or gold-plated technology.
As shown in Figure 3, the structure plan of planar coil 1 can adopt classical spiral circular, also can adopt square, hexagon, octagon and n limit shape (n >=4 are even number).
Referring again to Fig. 2, the live width w of planar coil 1 and turn-to-turn distance s should be as far as possible little, in the situation that PCB resolution technique allows, get tens microns; The inner diameter d of planar coil 1
1also should be as far as possible little, specifically depending on the volume size of detected object, make as much as possible the fill factor of planar coil 1 maximize; The thickness h of planar coil 1 generally between 20～50 microns, can be formed by stacking by the thick copper plate of half ounce (or 17.5 microns) thick copper foil layer, an ounce (or 35 microns) and the Gold plated Layer (or turmeric layer) of 38.1 nanometer thickness; The number of turn of planar coil 1 can be passed through the Larmor frequency under concrete application, and calculates the best number of turn in conjunction with signal to noise ratio (S/N ratio) theory.
The course of work of the present utility model is as follows: first on the instrument of network analyzer, adopt L-type resonance matching circuit, by low NMR probe resonance matching to 50 Ω based on PCB planar coil, again the NMR probe after resonance matching is put into permanent magnet (also can be put into superconducting magnet, the self-resonant frequency of sight line circle and determine).Then, tested liquid sample is put into kapillary, and kapillary is sealed at both ends, the kapillary that comprises sample after sealing directly put into planar coil 1 directly over; If tested is solid sample, adopt solid sample put on microslide, and by microslide directly put into planar coil 1 directly over.Sample issues magnetisation in the effect of main field, occurs magnetization vector in macroscopic view, and on microcosmic, in sample, thermal equilibrium state appears in intrinsic atomic nucleus system.Planar coil 1, under the effect of extraneous radio-frequency pulse excitation, produces the radio-frequency field of alternation, and radio-frequency field makes macroscopical magnetization vector occur that upset is until be turned to 90 °; At this moment close radio-frequency pulse, under the effect of relaxation, magnetization vector revert to original thermal equilibrium state again, be that magnetization vector is overturn again and got back to original 0 ° from 90 ° of positions, in this relaxation process, planar coil 1 cutting magnetic line has produced free induction decay (free induction decay, FID) signal.And the FID signal receiving just can obtain corresponding nuclear magnetic resonance time-domain signal or frequency-region signal by low noise amplification, detection and Fourier transform, by these NMR signal, just can carry out structure analysis and Components identification to sample.
Above-described specific embodiment; the purpose of this utility model, technical scheme and beneficial effect are further described; institute is understood that; the foregoing is only specific embodiment of the utility model; be not limited to the utility model; all within spirit of the present utility model and principle, any modification of making, be equal to replacement, improvement etc., within all should being included in protection domain of the present utility model.
Claims (2)
1. the low-field nuclear magnetic resonance based on printed circuit board (PCB) planar coil is popped one's head in, it is characterized in that it is substrate that this probe be take PCB substrate (5), in PCB substrate (5) top, be provided with planar coil (1), top lead-in wire (31), the first pad (41) and the second pad (42), the outer end of planar coil (1) by top go between (31) connect the first pad (41), the inner of planar coil (1) is connected with the second pad (42) by metallization inner via hole (21), bottom lead (32), metallization accessibke porosity (22).
2. the low-field nuclear magnetic resonance based on printed circuit board (PCB) planar coil according to claim 1 is popped one's head in, and the planform that it is characterized in that planar coil (1) is spiral circle, square, hexagon, octagon and n limit shape; N >=4 are even number.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320405489.1U CN203432927U (en) | 2013-07-08 | 2013-07-08 | Low-field nuclear magnetic resonance probe based on PCB (printed circuit board) planar coil |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201320405489.1U CN203432927U (en) | 2013-07-08 | 2013-07-08 | Low-field nuclear magnetic resonance probe based on PCB (printed circuit board) planar coil |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103439354A (en) * | 2013-07-08 | 2013-12-11 | 东南大学 | Low field nuclear magnetic resonance (NMR) probe based on planar coil of printed circuit board |
| CN107076813A (en) * | 2014-03-14 | 2017-08-18 | 通用医疗公司 | For low field, the system and method for multi channel imaging |
-
2013
- 2013-07-08 CN CN201320405489.1U patent/CN203432927U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103439354A (en) * | 2013-07-08 | 2013-12-11 | 东南大学 | Low field nuclear magnetic resonance (NMR) probe based on planar coil of printed circuit board |
| CN107076813A (en) * | 2014-03-14 | 2017-08-18 | 通用医疗公司 | For low field, the system and method for multi channel imaging |
| CN107076813B (en) * | 2014-03-14 | 2021-11-09 | 通用医疗公司 | System and method for low-field, multi-channel imaging |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140212 Termination date: 20150708 |
|
| EXPY | Termination of patent right or utility model |