CN203368895U - PET/SPECT/BNCT three use small medical cyclotron - Google Patents

PET/SPECT/BNCT three use small medical cyclotron Download PDF

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Publication number
CN203368895U
CN203368895U CN 201320413227 CN201320413227U CN203368895U CN 203368895 U CN203368895 U CN 203368895U CN 201320413227 CN201320413227 CN 201320413227 CN 201320413227 U CN201320413227 U CN 201320413227U CN 203368895 U CN203368895 U CN 203368895U
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small
medical cyclotron
injected
sized medical
cyclotron
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CN 201320413227
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周青梅
杰拉德·杜特
彼得·西格
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WUHAN DANGDAI NUCLEAR TECHNOLOGY Co Ltd
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WUHAN DANGDAI NUCLEAR TECHNOLOGY Co Ltd
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Abstract

The utility model discloses a PET/SPECT/BNCT three use small medical cyclotron which comprises an ion source system, an injection system, a high frequency system, a magnet system and a lead out system. An external ion source system is connected with the injection system. A particle is accelerated through the high frequency system, and at the same time is deflected through the magnet system. The injection system injects an intense current beam into the center area of the small medical cyclotron in a matching manner by using a charge neutralizing method. The compact small medical cyclotron provided by the utility model can ensure the volume and the vacuum degree of the accelerator, can greatly improve the current intensity, and can be simultaneously used for PET, SPECT and BNCT.

Description

A kind of PET/SPECT/BNCT tri-small-sized medical cyclotron
Technical field
The utility model relates to the medical cyclotron field, particularly a kind of PET/SPECT/BNCT tri-small-sized medical cyclotron.
Background technology
The small-sized medical cyclotron normally utilizes magnetic field to make charged particle do circumnutation, and through high-frequency electric field, repeatedly accelerate at the volley, educt beaming flow practice shooting to produce the diagnosis such as PET, SPECT or radioisotope use in treatment, and small-sized medical cyclotron that minority being is the is being researched and developed production BNCT neutron that is used for practicing shooting is arranged.Its basic structure comprises ion source system, main magnet system, radio frequency system, extraction system etc.At present such medical cyclotron is generally special purpose, be respectively used to produce PET with, radioisotope or BNCT neutron for SPECT.In malignant tumour, today that the cardiovascular and cerebrovascular disease incidence of disease is more and more higher, gradually can't meet the demand of hospital.
In modern Medical small-sized cyclotron, usually use inner ion source to produce H -ion; Part is used the required stream of accelerator Chang Yinwei of external ion source not high by force, and does not need mounting related components strong to improve stream.There is in addition the part accelerator to adopt the mode that buncher is installed to improve stream strong.But the accelerator for the mA magnitude, the effect of buncher is very limited, and can destroy the neutralization of injecting the line line, make the line envelope increase, bring beam loss, and the installation of buncher increased medical accelerator complexity, increased the volume of accelerator system, and then can't realize the medical cyclotron miniaturization.In large-scale accelerator or even TOKAMAK device, adopt the mode of pressure vessel inert gas injecting to make H -the ion neutralization, but this is not suitable for using on the injection line of compact compact cyclotron.In compact small-sized medical cyclotron field, can guarantee the requirement that the cyclotron volume is little, improve again Beam Current strong, be that those skilled in the art thirst for the technical barrier solved simultaneously, and this application for medical cyclotron is significant.
Summary of the invention
The utility model has overcome the deficiencies in the prior art, and a kind of accelerator volume and vacuum degree of both having guaranteed is provided, and can improve greatly again stream strong, can be simultaneously for the compact small-sized medical cyclotron of PET, SPECT and BNCT.
In order to solve the problems of the technologies described above, the utility model is achieved through the following technical solutions:
A kind of PET/SPECT/BNCT tri-small-sized medical cyclotron, comprise ion source system, injected system, radio frequency system, magnet system and extraction system, external ion source system is connected with injected system, when particle accelerates by radio frequency system, by magnet system deflection, wherein, described injected system adopts the mode of charging neutrality that the high-current beam coupling is injected into to small-sized medical cyclotron center.
Further, described injected system adopts the mode of regulating injection line middle part background gas pressure to realize charging neutrality, and the high-current beam coupling completed in compact small-sized medical cyclotron is injected.
Further, the middle part of the injection line in described injected system background gas pressure is 5 * 10 -5~5 * 10 -6mbar.
Further, described extraction system is 3~8 line extraction systems, and its mode that adopts part to peel off realizes drawing to the line of mA magnitude from μ A magnitude.
Further, described injected system is coaxial with magnet system, and the particle that accelerate is the axial injection from magnet by injected system.
Further, described magnetic pole radius is 0.503m, and magnetic field intensity is 2.0kGs~18.5kGs.
Further, described radio frequency system contains two λ/4 high frequency resonate cavities, and the high frequency frequency is 72.5~73.5MHz, and the high frequency accelerating voltage is 35~45kV.
Further, the terminal of the deflector central orbit of described injected system arrives the starting point of the acceleration equilibrium orbit of radio frequency system, axial coordinate and momentum at this deflector central orbit are zero and radial alignment, make the center line enter corresponding phase space acceptance and focus on, accelerate on radial and axial.
Compared with prior art, the beneficial effects of the utility model are:
Injected system of the present utility model has changed law-current beam/middle high-current beam and has spread the injection mode of use buncher of system, and utilize the charging neutrality principle, effectively suppress space charge effect, realized that the high current of low energy end injects, realized the different couplings that stream is strong of injecting.Particularly, for the compact medical cyclotron, space is comparatively narrow and small, and has under the condition of higher vacuum requirement, adopts and relies on moderate background gas pressure and the poor method of local Vacuum Pressure of control to realize neutral charge.The utility model, by the reasonable coordination of ion source system, injected system etc., can be drawn the high current proton beam up to the 15MeV left and right, can be for the production of the PET radionuclide 18f, 13n, 11c, 15o, can produce the SPECT radionuclide again 64cu, 67ga etc., also can practice shooting simultaneously and produce neutron beam to carry out the BNCT treatment, realized the effect of device three use.
The mode that the utility model is regulated local background's gas pressure does not need to increase the length of injecting line, guarantee medical cyclotron compact conformation, miniaturization, though do not accomplish 100% charging neutrality, can realize more than 95%, thus the injection difficult problem of the low energy 10mA magnitude of solution injected system.
The accompanying drawing explanation
Fig. 1 medical cyclotron structural representation
The sector magnet of Fig. 2 magnet system and the schematic diagram of frequency cavity
1 extraction system one, 2 ion source systems, 3 injected systems, 4 main magnet system, 5 magnetic poles, 6 radio frequency systems, 7 magnet paddy districts, 8 extraction systems two, 9 extraction systems three, 10 extraction systems four
Embodiment
Below in conjunction with accompanying drawing and embodiment, the utility model is described in further detail:
As shown in Figure 1, the primary structure of medical cyclotron that the utility model is carried forms and comprises ion source system 2, injected system 3, main magnet system 4, radio frequency system 6, two-way extraction system 1, extraction system 28, extraction system 39, the extraction system 4 10 etc. peeled off.Wherein ion source system 2 produces the high current negative hydrogen ions, by injected system 3 by H -particle is injected in accelerator and is accelerated.Injected system 3 coaxially arranges with main magnet system 4, negative hydrogen ion from the axial injection of main magnet to accelerator.The accelerating voltage that provides by radio frequency system 6 accelerates, then by extraction system by H -ion is peeled off into proton beam and is drawn.
For example, accelerating H -ion is to the cyclotron of this type of highest energy 15MeV, the magnet arrangement of selecting as shown in Figure 2, include four pairs of magnetic poles 5, each magnetic pole 5 is the straight flange sector structure, forms magnet paddy district 7 between two adjacent magnetic poles 5, in order to radio frequency system 6 to be installed, as equipment such as high frequency resonate cavities, approximately 50 ° of each sector magnetic pole angles, magnetic pole radius 0.503m, the magnetic field range of formation is 2.0kGs~18.5kGs.Radio frequency system comprises two λ/4 high frequency resonate cavities and high frequency transmitter, and harmonic mode is 4, in order to accelerate H -ion, the acceleration frequency is 73MHz, accelerating voltage is 35kV~45kV.
Ion source system 2 can produce the H that stream is 30kV for 1mA~10mA, energy by force -ion, to meet the strong different demands of convection current in the PET/SPECT/BNCT use.The strong H of various flows that injected system 3 produces ion source 2 -the ion beam coupling is injected in accelerator.Injected system 3 adopts the mode of charging neutrality to complete injection and the coupling of high-current beam, and this charging neutrality is rely on the pressure of regulating injected system 3 injection line middle part background gas and utilize the mode of parital vacuum pressure reduction to realize, wherein the pressure of background gas is 5 * 10 -5~5 * 10 -6mbar, for the H of 10mA left and right -line, the pressure of background gas is about 5 * 10 -5mbar.After the vertical injection of ion, by the high-voltage deflection plate, deflect on horizontal plane, the ingehious design of center makes the terminal of deflector central orbit arrive the starting point of accelerating equilibrium orbit, axial coordinate and momentum at this deflector central orbit are zero, to eliminate axial free oscillation, and radial alignment, make the center line enter corresponding phase space acceptance and focus on, accelerate, more than the acceptance of phase space reaches 40 degree on radial and axial.These measures all make the beam loss in accelerator reduce, and have realized that accelerator draws Gao Liuqiang to meet the demand of PET/SPECT/BNCT simultaneously.
The H accelerated -line peels off after two electronics and forms proton beam and draw accelerator by peeling off extraction system, can draw 3~4 bundle proton beams at both direction simultaneously, it is extraction system 1,8,9,10 in Fig. 1, the mode that adopts part to peel off realizes drawing to the line of mA magnitude from μ A magnitude, wherein extraction system 9,10 can be drawn weak current/middle high current to use radionuclide production for PET, and extraction system 1,8 is drawn mA magnitude high current line to produce radionuclide and the neutron beam for SPECT, BNCT.By imperfect Flow Field Numerical component and the imperfect harmonic wave of strict controlling magnetic field, and adopt the control mode of strict stripping film position to peel off to realize part.In addition, this accelerator can be expanded the quantity to 4 of drawing direction, each draws direction can draw 2 proton beams, this accelerator can draw simultaneously 3~8 bundle proton beams with for the production of, shortened and changed the cycle of producing target, improved the production efficiency of accelerator.

Claims (8)

1. PET/SPECT/BNCT tri-a small-sized medical cyclotron, comprise ion source system, injected system, radio frequency system, magnet system and extraction system, external ion source system is connected with injected system, when particle accelerates by radio frequency system, by magnet system deflection, it is characterized in that, described injected system adopts the mode of charging neutrality that the high-current beam coupling is injected into to small-sized medical cyclotron center.
2. according to claim 1 a kind of three use the small-sized medical cyclotron, it is characterized in that, described injected system adopts the mode of regulating injection line middle part background gas pressure to realize charging neutrality, and the high-current beam coupling completed in compact small-sized medical cyclotron is injected.
3. according to claim 2 a kind of three use the small-sized medical cyclotron, it is characterized in that, the injection line middle part background gas pressure in described injected system is 5 * 10 -5~5 * 10 -6mbar.
4. according to claim 1 a kind of three use the small-sized medical cyclotron, it is characterized in that, described extraction system is 3~8 line extraction systems, and its mode that adopts part to peel off realizes drawing to the line of mA magnitude from μ A magnitude.
5. according to claim 1 a kind of three use the small-sized medical cyclotron, it is characterized in that, described injected system is coaxial with magnet system, and the particle that accelerate is the axial injection from magnet by injected system.
6. according to claim 1 a kind of three use the small-sized medical cyclotron, it is characterized in that, described magnetic pole radius is 0.503m, and magnetic field intensity is 2.0kGs~18.5kGs.
7. according to claim 1 a kind of three use the small-sized medical cyclotron, it is characterized in that, described radio frequency system contains two λ/4 high frequency resonate cavities, and the high frequency frequency is 72.5~73.5MHz, and the high frequency accelerating voltage is 35~45kV.
8. a kind of three property small-sized medical cyclotrons according to claim 1, it is characterized in that, the terminal of the deflector central orbit of described injected system arrives the starting point of the acceleration equilibrium orbit of radio frequency system, axial coordinate and momentum at this deflector central orbit are zero and radial alignment, make the center line enter corresponding phase space acceptance and focus on, accelerate on radial and axial.
CN 201320413227 2013-07-12 2013-07-12 PET/SPECT/BNCT three use small medical cyclotron Expired - Fee Related CN203368895U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103327725A (en) * 2013-07-12 2013-09-25 武汉当代核技术有限公司 PET/SPECT/BNCT (positron emission tomography/single photon emission computed tomography/boron neutron capture therapy) three-purpose small medical cyclotron
CN110430657A (en) * 2019-08-08 2019-11-08 合肥中科离子医学技术装备有限公司 Interior pouring-in superconducting cyclotron center fission layer-stepping magnet chock structure

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103327725A (en) * 2013-07-12 2013-09-25 武汉当代核技术有限公司 PET/SPECT/BNCT (positron emission tomography/single photon emission computed tomography/boron neutron capture therapy) three-purpose small medical cyclotron
CN103327725B (en) * 2013-07-12 2016-05-04 武汉当代核技术有限公司 A kind of PET/SPECT/BNCT tri-small-sized medical cyclotron
CN110430657A (en) * 2019-08-08 2019-11-08 合肥中科离子医学技术装备有限公司 Interior pouring-in superconducting cyclotron center fission layer-stepping magnet chock structure
CN110430657B (en) * 2019-08-08 2023-10-13 合肥中科离子医学技术装备有限公司 Internal injection type superconductive cyclotron center distinguishing body layered magnet chock structure

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Granted publication date: 20131225

Termination date: 20170712