CN203310799U - Blood glucose test strip with multiple working electrodes - Google Patents
Blood glucose test strip with multiple working electrodes Download PDFInfo
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- CN203310799U CN203310799U CN2013202861909U CN201320286190U CN203310799U CN 203310799 U CN203310799 U CN 203310799U CN 2013202861909 U CN2013202861909 U CN 2013202861909U CN 201320286190 U CN201320286190 U CN 201320286190U CN 203310799 U CN203310799 U CN 203310799U
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Abstract
The utility model belongs to the technical field of biological sensing and in particular relates to a blood glucose test strip with multiple working electrodes. The blood glucose test strip is formed by a substrate layer (2), an electrode layer (3) with at least two working electrodes, an enzyme layer (4), a covering layer (5) and an upper spacer layer (6) for protecting the upper end of the covering layer, which fit with one another from bottom to top. The blood glucose test strip can be used for simultaneously testing the blood glucose concentration and averaging by the multiple working electrodes, and the test result is more accurate.
Description
Technical field
The utility model belongs to the biosensor technique field, is specifically related to the blood sugar test paper that a kind of multiplex (MUX) makes electrode.
Background technology
Commercially available blood glucose meter major part is all electrochemical process now, the Momentary electronic produced during glucose response in enzyme and blood is captured by electron mediator, electronics forms electric current under the effect of voltage, blood glucose meter detection electric current the blood glucose value that electric current is changed in blood show, therefore, the accuracy of blood glucose meter test result is relevant with the electrode material on test strip for blood-sugar to a great extent.
Current most of blood sugar test paper is to use graphite (carbon) as induction electrode, and a part is used silver electrode, and it is to use palladium electrode that sub-fraction is arranged.While using graphite electrode, the easy corroding electrode of sweat on hand or cosmetics, and have influence on the blood sugar test accuracy.
While measuring blood sugar, need on corresponding electrode, apply constant DC voltage, by the weak current of accurate measurement reaction zone enzyme with the generation of glucose generation redox reaction, and according to the relation of current value and blood sugar concentration, inverse goes out corresponding blood sugar concentration.
Present commercial electrochemical blood sugar test paper roughly divides two classes: two electrode structures and three-electrode structure, two electrode structures are comprised of a working electrode and a contrast electrode, and three-electrode structure consists of a working electrode, a contrast electrode and a trigger electrode.Two electrode structures and three-electrode structure respectively have the merits and demerits of oneself, two electrode structures are made simple, but easily occur that there is no fully to mix a result produced with regard to the beginning sense data inaccurate due to reagent and sample, in three-electrode structure, the design of trigger electrode can well be avoided this problem.But be that two electrodes or three electrodes all only have a working electrode, that is to say that each measurement all only produces a data result, can't judge whether this data result is accurate.
The utility model content
For the deficiencies in the prior art, the utility model aims to provide the blood sugar test paper that a kind of multiplex (MUX) makes electrode, and this working electrode employing gold electrode, and this blood sugar test paper adopts multiplex (MUX) to make electrode and measures simultaneously blood sugar concentration and average, and measurement result is more accurate.
For achieving the above object, the technical solution of the utility model is:
A kind of multiplex (MUX) makes the blood sugar test paper of electrode, comprises substrate layer, by substrate layer, the electrode layer that comprises at least two working electrodes, enzyme layer, overlayer with for the protection of the upper spacer layer of overlayer upper end, is sticked to form successively from the bottom to top.
Described electrode layer is preferably the gold electrode layer.
Described substrate layer preferably adopts the substrate layer of any one material in poly terephthalic acid diethylester, Polyvinylchloride, polypropylene.
Described electrode layer is preferably by working electrode a, contrast electrode, working electrode b, trigger electrode and connection electrode connect to form, and by near extremely order far away, are working electrode a, contrast electrode, working electrode b, trigger electrode and connection electrode according to the distance on the top from the end of sucking blood successively; Connect the insertion end place that electrode is arranged on electrode layer.
Described overlayer upper end preferably has pore.
Below utility model is further explained and illustrates:
This strip comprises: substrate 2, electrode layer 3, enzyme layer 4, overlayer 5, upper partition 6
(1) substrate 2: adopt a kind of in poly terephthalic acid diethylester (PET), Polyvinylchloride (PVC), polypropylene (PP);
(2) electrode layer 3: use the material selection gold, the technology by laser splash forms uniform gold layer at substrate surface, and adopts the means of laser beam marking to depict the electrode lines on the gold layer.For graphite electrode, the oxidation resistance of gold is very strong, and gold electrode is corrosion-resistant, should not be subjected to the impact of an outer environment, can prevent that the interference of the various radiation such as mobile phone, stable performance are lasting, and electric conductivity, sensing capabilities are fabulous, and accuracy is high.The sheet resistance of material with carbon element is 15～20 Ω, and the sheet resistance of ag material is 10～15 m Ω, and the sheet resistance of gold copper-base alloy can reach below 10 m Ω.According to Ohm law, under constant voltage, the sheet resistance of material is less, and current value is larger.Therefore, use gold than use silver and graphite electrode, can obtain more obvious current value as induction electrode, calculate corresponding blood glucose concentration value also more accurate.
Electrode system comprises that at least two working electrodes, reference electrode 11, trigger electrode 10 and one connect electrode 7.Wherein two working electrodes are used for, with two electrode pairs of reference electrode formation, a blood sample is carried out to twice measurement, the data that finally show on corresponding blood glucose meter are the mean value of this twice measurement result, and the design of two working electrodes can improve the accuracy of blood glucose measurement greatly.
(3) the enzyme layer 4, namely reaction zone.
(4) overlayer 5: be used for the part of covers electrode layer, the front end of this overlayer 5 has a pore 12, air when being used for discharging blood and entering siphon passage, wherein the part of pore 12 unlapped electrode layers forms the reaction zone with an openend, namely the zone that arranges of enzyme layer.
(5) upper partition 6: be positioned at tectal upper end, be used for the protective reaction district not to be subjected to the interference of external environment.
Compared with prior art, advantage of the present utility model is:
1, the design of at least two working electrodes, by measuring repeatedly blood glucose value result, the automatic repeatedly measurement result of instrument compares, and comparative result is averaged in the error allowed band, therefore can greatly reduce the error of blood glucose measurement, improve the accuracy of blood glucose measurement.
2, adopt gold electrode, corrosion-resistant, be not subject to the impact of an outer environment, can prevent that the interference of the various radiation such as mobile phone, stable performance are lasting, electric conductivity, sensing capabilities are fabulous, and accuracy is high.
3, the design of trigger electrode can be avoided not filling the blood glucose value that whole reaction zone causes and measuring inaccurate due to blood.
The accompanying drawing explanation
Fig. 1 is the blood sugar test paper hierarchy schematic diagram from the bottom to top that multiplex (MUX) of the present utility model makes electrode;
Fig. 2 is the one-piece construction schematic diagram of the multiplex (MUX) of the present utility model blood sugar test paper of making electrode;
Wherein 1 is the finished product blood sugar test paper; The 2nd, substrate layer; The 3rd, electrode layer; The 4th, enzyme layer (namely reaction zone); The 5th, overlayer; The 6th, upper spacer layer; The 7th, connect electrode; The 8th, working electrode a; The 9th, working electrode b; The 10th, trigger electrode; The 11st, contrast electrode; The 12nd, pore; The 13rd, the end of sucking blood; The 14th, insertion end; The 15th, dielectric film.
Embodiment
Below in conjunction with embodiment, the utility model is described further.
As depicted in figs. 1 and 2, a kind of multiplex (MUX) makes the blood sugar test paper of electrode, comprises substrate layer 1, by substrate layer 2, the electrode layer 3 that comprises two working electrodes, enzyme layer 4, overlayer 5 with for the protection of the upper spacer layer 6 of overlayer upper end, is sticked to form successively from the bottom to top.
Described electrode layer 2 is the gold electrode layer.
Described substrate layer 1 adopts the substrate layer of any one material in poly terephthalic acid diethylester, Polyvinylchloride, polypropylene.
Described electrode layer 3 is by working electrode a8, contrast electrode 11, working electrode b9, trigger electrode 10 and connect electrode 7 and connect to form, and according to the distance on the top from the end 13 of sucking blood by near to order far away be working electrode a8, contrast electrode 11, working electrode b9, trigger electrode 10 and connection electrode 7 successively; Connect insertion end 14 places that electrode 7 is arranged on electrode layer 3.
By the suck blood design of end 13 asymmetric trapezium structures of test paper, can facilitate the user to judge fast test paper suck blood end and the position of insertion end and the two ends up and down of differentiation test paper.And in user's measuring process, it is mouthfuls 16 more easily found that this design can make to suck blood, and make mouthful 16 drops of blood of more easily locating on finger tip of sucking blood.
Application:
The step of measuring the glucose in blood value with the utility model test paper is:
A, this test paper insertion end 14 that faces up is inserted in corresponding blood glucose meter, test paper and instrument form loop, instrument Auto Power On;
B, from sucking blood, mouthfuls 16 enter reaction zone (namely the enzyme layer 4) when blood sample, contact successively working electrode a8, reference electrode 11, working electrode b9, trigger electrode 10, the enzyme reagent generation redox reaction of the glucose in blood and reaction zone, record one group of current data between working electrode a8 and reference electrode 11, between working electrode b9 and reference electrode 11, record second group of current data, these two groups of data calculate corresponding blood-sugar content through the processing of corresponding blood glucose meter.
Claims (4)
1. a multiplex (MUX) makes the blood sugar test paper of electrode, comprise substrate layer (1), it is characterized in that, by substrate layer (2), the electrode layer (3) that comprises two working electrodes, enzyme layer (4), overlayer (5) with for the protection of the upper spacer layer (6) of overlayer upper end, be sticked to form successively from the bottom to top; Described electrode layer (3) is by working electrode a(8), contrast electrode (11), working electrode b(9), trigger electrode (10) and connect electrode (7) and connect to form, and according to the distance on the top from the end (13) of sucking blood, be working electrode a(8 successively by order far away closely extremely), contrast electrode (11), working electrode b(9), trigger electrode (10) and connection electrode (7); Connection electrode (7) is arranged on the insertion end (14) of electrode layer (3) and locates.
2. the multiplex (MUX) makes the blood sugar test paper of electrode according to claim 1, it is characterized in that, described electrode layer (2) is the gold electrode layer.
3. according to the described multiplex (MUX) of claim 1 or 2, make the blood sugar test paper of electrode, it is characterized in that, described substrate layer (1) adopts the substrate layer of any one material in poly terephthalic acid diethylester, Polyvinylchloride, polypropylene.
4. according to the described multiplex (MUX) of claim 1 or 2, make the blood sugar test paper of electrode, it is characterized in that, there is pore (12) described overlayer (5) upper end.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013202861909U CN203310799U (en) | 2013-05-23 | 2013-05-23 | Blood glucose test strip with multiple working electrodes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013202861909U CN203310799U (en) | 2013-05-23 | 2013-05-23 | Blood glucose test strip with multiple working electrodes |
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| Publication Number | Publication Date |
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| CN203310799U true CN203310799U (en) | 2013-11-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2013202861909U Expired - Fee Related CN203310799U (en) | 2013-05-23 | 2013-05-23 | Blood glucose test strip with multiple working electrodes |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105510391A (en) * | 2014-09-22 | 2016-04-20 | 英科新创(厦门)科技有限公司 | Electrode type blood sugar test strip |
| CN105973946A (en) * | 2016-05-05 | 2016-09-28 | 四川拉雅微科技有限公司 | High-precision blood sugar test paper with hematokrit measurement and compensation function |
| CN109115853A (en) * | 2018-09-26 | 2019-01-01 | 贵州拉雅科技有限公司 | A kind of high-precision uric acid electrochemistry test paper with hematocrit compensation |
| CN109142488A (en) * | 2018-09-26 | 2019-01-04 | 贵州拉雅科技有限公司 | A kind of electrochemistry test paper and its application method with impedance identification |
| CN109270142A (en) * | 2018-09-26 | 2019-01-25 | 贵州拉雅科技有限公司 | A kind of high-precision total cholesterol electrochemistry test paper with hematocrit compensation |
-
2013
- 2013-05-23 CN CN2013202861909U patent/CN203310799U/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105510391A (en) * | 2014-09-22 | 2016-04-20 | 英科新创(厦门)科技有限公司 | Electrode type blood sugar test strip |
| CN105510391B (en) * | 2014-09-22 | 2018-08-24 | 英科新创(厦门)科技有限公司 | A kind of electric pole type blood glucose strip |
| CN105973946A (en) * | 2016-05-05 | 2016-09-28 | 四川拉雅微科技有限公司 | High-precision blood sugar test paper with hematokrit measurement and compensation function |
| CN109115853A (en) * | 2018-09-26 | 2019-01-01 | 贵州拉雅科技有限公司 | A kind of high-precision uric acid electrochemistry test paper with hematocrit compensation |
| CN109142488A (en) * | 2018-09-26 | 2019-01-04 | 贵州拉雅科技有限公司 | A kind of electrochemistry test paper and its application method with impedance identification |
| CN109270142A (en) * | 2018-09-26 | 2019-01-25 | 贵州拉雅科技有限公司 | A kind of high-precision total cholesterol electrochemistry test paper with hematocrit compensation |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131127 Termination date: 20140523 |